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Gene: PTPRU (protein tyrosine phosphatase receptor type U) Pan paniscus

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Symbol:

PTPRU

Name:

protein tyrosine phosphatase receptor type U

RGD ID:

11947171

Description:

ENCODES a protein that exhibits beta-catenin binding (inferred); histone H2AXY142 phosphatase activity (inferred); non-membrane spanning protein tyrosine phosphatase activity (inferred); INVOLVED IN animal organ regeneration (ortholog); homotypic cell-cell adhesion (ortholog); protein dephosphorylation (ortholog); ASSOCIATED WITH Dwarfism (ortholog); Experimental Diabetes Mellitus (ortholog); hypertension (ortholog); FOUND IN cell-cell junction (inferred); membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC100974128; LOC100985291; LOC103783254; protein tyrosine phosphatase, receptor type, U; receptor-type tyrosine-protein phosphatase U; receptor-type tyrosine-protein phosphatase U-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	197,516,640 - 197,606,767 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	196,635,952 - 196,726,070 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	28,507,078 - 28,597,154 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	29,556,675 - 29,623,247 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	29,551,912 - 29,622,104 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Dwarfism (ISO)

Experimental Diabetes Mellitus (ISO)

hypertension (ISO)

membranous glomerulonephritis (ISO)

nephrosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ regeneration (ISO)

chromatin remodeling (IEA)

homotypic cell-cell adhesion (IEA,ISO)

negative regulation of canonical Wnt signaling pathway (IEA)

negative regulation of cell migration (IEA)

negative regulation of cell population proliferation (IEA)

positive regulation of cell-cell adhesion mediated by cadherin (IEA)

protein dephosphorylation (ISO)

protein localization to cell surface (IEA)

response to glucocorticoid (ISO)

Cellular Component

cell-cell junction (IEA)

membrane (IEA)

Molecular Function

beta-catenin binding (IEA)

histone H2AXY142 phosphatase activity (IEA)

non-membrane spanning protein tyrosine phosphatase activity (IEA)

phosphoprotein phosphatase activity (IEA)

protein binding (ISO)

protein tyrosine phosphatase activity (IEA)

protein tyrosine phosphatase activity, metal-dependent (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

PTPRU
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	197,516,640 - 197,606,767 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	196,635,952 - 196,726,070 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	28,507,078 - 28,597,154 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	29,556,675 - 29,623,247 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	29,551,912 - 29,622,104 (+)	Ensembl	panpan1.1		panPan2

PTPRU
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	29,236,522 - 29,326,800 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	29,236,516 - 29,326,813 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	29,563,034 - 29,653,312 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	29,435,634 - 29,525,903 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	29,383,643 - 29,473,927	NCBI
Celera	1	27,959,180 - 28,049,910 (+)	NCBI		Celera
Cytogenetic Map	1	p35.3	NCBI
HuRef	1	27,814,346 - 27,905,164 (+)	NCBI		HuRef
CHM1_1	1	29,678,424 - 29,768,677 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	29,079,179 - 29,169,454 (+)	NCBI		T2T-CHM13v2.0

Ptpru
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	131,495,768 - 131,565,617 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	131,495,768 - 131,565,599 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	131,768,457 - 131,838,306 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	131,768,457 - 131,838,288 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	131,324,372 - 131,394,193 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	131,040,533 - 131,110,354 (-)	NCBI		MGSCv36	mm8
Celera	4	129,928,568 - 129,998,810 (-)	NCBI		Celera
Cytogenetic Map	4	D2.3	NCBI
cM Map	4	64.5	NCBI

Ptpru
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	149,234,624 - 149,308,857 (-)	NCBI		GRCr8
mRatBN7.2	5	143,950,542 - 144,024,791 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	143,950,965 - 144,024,768 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	146,656,411 - 146,730,321 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	148,426,261 - 148,500,169 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	148,413,833 - 148,488,044 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	149,922,374 - 149,996,352 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	149,922,352 - 149,996,334 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	153,601,160 - 153,675,514 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	150,612,095 - 150,695,183 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	150,660,034 - 150,668,570 (-)	NCBI
Celera	5	142,397,414 - 142,468,771 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Ptpru
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	8,223,692 - 8,296,769 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	8,223,773 - 8,296,769 (+)	NCBI	ChiLan1.0	ChiLan1.0

PTPRU
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	71,284,979 - 71,363,253 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	71,285,851 - 71,363,691 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	67,861,226 - 67,939,839 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	71,844,918 - 71,923,499 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	71,844,933 - 71,923,492 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	68,673,740 - 68,752,383 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	69,681,824 - 69,760,389 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	70,679,504 - 70,758,203 (-)	NCBI		UU_Cfam_GSD_1.0

Ptpru
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	47,268,246 - 47,438,405 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	13,197,786 - 13,263,362 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	13,197,786 - 13,263,187 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PTPRU
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	86,137,737 - 86,228,145 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	86,137,743 - 86,228,148 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	80,024,234 - 80,106,252 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PTPRU
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	103,497,681 - 103,586,494 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	103,498,839 - 103,586,348 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	12,943,572 - 13,032,266 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ptpru
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	12,994,521 - 13,073,251 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	12,994,562 - 13,072,723 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008953442	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959699	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959710	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959719	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095802	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095822	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095835	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063593431	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000002225 ⟹ ENSPPAP00000000527

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	29,551,912 - 29,622,104 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000002228 ⟹ ENSPPAP00000000530

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	29,551,912 - 29,622,104 (+)	Ensembl

RefSeq Acc Id:

XM_008953442 ⟹ XP_008951690

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,583,115 (-)	NCBI
NHGRI_mPanPan1	1	196,635,952 - 196,702,396 (-)	NCBI
Mhudiblu_PPA_v0	1	28,530,692 - 28,597,154 (+)	NCBI
PanPan1.1	1	29,556,675 - 29,623,247 (+)	NCBI

Sequence:

show sequence

GGGGCCGGCAGGGTGTCGCTGGGGCGCTATCTGAAGATGGGCCTGTGGAAATGGCAGTGGCCCA
GCCGGGATGAGATCTGATCTAGGGGTCGGGGCTGGCTTCGAGGGGGACGGACAGGGTCAAGAGC
CCCCAACTCCCATCGCGCCCCCACAGCTGCTGCGTGCTGGCCCCACCTACCTCATCATCCAGCT
AAACACCAACTCCATCATTGGCGACGGGCCGATCGTGCGCAAGGAGATTGAGTACCGCATGGCG
CGCGGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAGACCTACAAGCTGTGGCACCTCGACC
CCGACACAGAGTATGAGATCAGCGTGCTGCTCACGCGTCCCGGAGACGGCGGCACTGGCCGCCC
TGGGCCACCCCTCATCAGCCGCACCAAATGCGCAGAGCCCATGAGGGCCCCCAAAGGCCTGGCT
TTTGCTGAGATCCAGGCCCGCCAGCTGACCCTGCAGTGGGAACCACTGGGCTACAACGTGACGC
GTTGCCACACCTATACTGTGTCGCTGTGCTATCACTACACCCTGGGCAGCAGCCACAATCAGAC
CATCCGAGAGTGTGTGAAGACAGAGCAAGGTGTCAGCCGCTACACCATCAAGAACCTGCTGCCC
TATCGGAACGTTCACGTGAGGCTTGTCCTCACTAACCCTGAGGGGCGCAAAGAGGGCAAGGAGG
TCACTTTCCAGACGGATGAGGATGTGCCCAGTGGGATTGCAGCCGAGTCCCTGACCTTCACTCC
ACTGGAGGACATGATCTTCCTCAAGTGGGAGGAGCCCCAGGAGCCCAATGGTCTCATCACCCAG
TATGAGATCAGCTACCAGAGCATCGAGTCATCAGACCCGGCAGTGAACGTGCCAGGCCCACGAC
GTACCATCTCCAAGCTCCGCAATGAGACCTACCATGTCTTCTCCAACCTGCACCCAGGCACCAC
CTACCTATTCTCCGTGCGAGCCCGCACAGGCAAAGGCTTCGGCCAGGCGGCACTCACTGAGATA
ACCACTAACATCTCTGCTCCCAGCTTTGATTATGCCGACATGCCGTCACCCCTGGGCGAGTCTG
AGAACACCATCACCGTGCTGCTGAGGCCGGCACAGGGCCGCGGTGCGCCCATCAGTGTGTACCA
GGTGATTGTGGAGGAGGAGCGGGCGCGGAGGCTGCGGCGGGAGCCAGGTGGACAGGACTGCTTC
CCAGTGCCATTGACCTTCGAGGCGGCGCTGGCCCGAGGCCTGGTGCACTACTTCGGGGCCGAAC
TGGTGGCCAGCAGTCTACCTGAGGCCATGCCCTTTACCGTGGGTGACAACCAGACCTACCGAGG
CTTCTGGAACCCACCACTTGAGCCTAGGAAGGCCTATCTCATCTACTTCCAGGCAGCAAGCCAC
CTGAAGGGGGAGACCCGGCTGAATTGCATCCGCATTGCCAGGAAAGCTGCCTGCAAGGAAAGCA
AGCGGCCCCTGGAGGTGTCCCAGAGATCGGAGGAGATGGGGCTTATCCTGGGCATCTGTGCAGG
GGGGCTTGCTGTCCTCATCCTTCTCCTGGGTGCCATCATTGTCATCATCCGCAAAGGGAGAGAC
CACTATGCCTACTCCTACTACCCGAAGCCGGTGAACATGACCAAGGCCACCGTCAACTACCGCC
AGGAGAAGACACACATGATGAGCGCCGTGGACCGCAGCTTCACAGACCAGAGCACCCTGCAGGA
GGACGAGCGGCTGGGCCTGTCCTTCATGGACACCCATGGCTACAGCACCCGGGGAGACCAGCGC
AGCGGTGGGGTCACTGAGGCCAGCAGCCTCCTGGGGGGCTCCCCGAGGCGTCCCTGTGGCCGGA
AGGGCTCCCCATACCACACGGGGCAGCTGCACCCTGCGGTGCGTGTCGCAGACCTTCTGCAGCA
CATCAACCAGATGAAGACGGCCGAGGGTTACGGCTTCAAGCAGGAGTATGAGAGCTTCTTTGAA
GGCTGGGACGCCACAAAGAAGAAAGACAAGGTCAAGGGCAGCCGGCAGGAGCCAATGCCTGCCT
ATGATCGGCACCGAGTGAAACTGCACCCGATGCTGGGAGACCCCAATGCCGACTACATTAATGC
CAACTACATAGATATTCGGATAAACCGAGAAGGTTACCACAGGTCAAACCACTTCATAGCCACT
CAAGGGCCGAAGCCTGAGATGGTCTACGACTTCTGGCGTATGGTGTGGCAGGAGCACTGTTCCA
GCATCGTCATGATCACCAAGCTGGTCGAGGTGGGCAGGGTGAAATGCTCACGGTATTGGCCGGA
GGACTCAGACACCTACGGGGACATCAAGATTACGCTGGTGAAGACAGAGACCCTGGCTGAGTAT
GTCGTGCGCACTTTTGCCCTGGAGCGGAGAGGCTACTCTGCCCGGCACGAGGTCCGCCAGTTCC
ACTTCACAGCGTGGCCAGAGCATGGCGTCCCCTACCACGCCACGGGGCTGCTGGCTTTCATCCG
GCGCGTGAAGGCCTCCACCCCACCTGATGCCGGGCCCATTGTCATCCACTGCAGCGCGGGCACC
GGCCGCACAGGTTGCTATATCGTCCTGGATGTGATGCTGGACATGGCAGAGTGTGAGGGCGTCG
TGGACATTTACAACTGTGTGAAGACTCTCTGCTCCCGGCGTGTCAACATGATCCAGACTGAGGA
GCAGTACATCTTCATTCATGATGCAATCCTGGAGGCCTGCCTGTGTGGGGAGACCACCATCCCT
GTCAGTGAGTTCAAGGCCACCTACAAGGAGATGATCCGCATTGATCCTCAGAGTAATTCCTCCC
AGCTGCGGGAAGAGTTCCAGACGCTGAACTCGGTCACCCCGCCACTGGACGTGGAGGAGTGCAG
CATCGCCCTGTTGCCCCGGAACCGCGACAAGAACCGCAGCATGGACGTCCTGCCACCCGACCGC
TGCCTGCCCTTCCTCATCTCCACTGATGGGGACCCCAACAACTACATTAATGCAGCCCTGACTG
ACAGCTACACACGGAGTGCGGCCTTCATCGTGACCCTGCACCCGCTGCAGAGCACCACGCCCGA
CTTCTGGCGGCTGGTCTACGATTACGGGTGCACCTCCATCGTCATGCTCAACCAGCTGAACCAG
TCCAACTCCGCCTGGCCCTGCCTGCAGTACTGGCCAGAGCCAGGCCGGCAGCAATATGGCCTCA
TGGAGGTGGAGTTTATGTCGGGCACAGCTGATGAAGACTTAGTGGCTCGAGTCTTCCGGGTGCA
GAACATCTCTCGGTTGCAGGAGGGGCACCTGCTGGTGCGGCACTTCCAGTTCCTGCGCTGGTCT
GCATACCGGGACACACCTGACTCCAAGAAGGCCTTCTTGCACCTGCTGGCTGAGGTGGACAAGT
GGCAGGCCGAGAGTGGGGATGGGCGCACCATCGTGCACTGCCTAAACGGGGGAGGACGCAGCGG
CACCTTCTGCGCCTGCGCCACGGTCCTGGAGATGATCCGCTGCCACAACTTGGTGGACGTTTTC
TTTGCTGCCAAAACCCTCCGGAACTACAAACCCAACATGGTGGAGACCATGGATCAGTACCACT
TTTGCTACGATGTGGCCCTGGAGTACTTGGAGGGGCTGGAGTCAAGATAGCGGGGCCCTGGCCT
GGGGCACCCACTGCACACTCAGGGCCAGACCCACCATCCTGGACTGGCGAGGAAGATCAGTGCC
TCCTGCTCTGCCCAAACACACTCCCATGGGGCAAGCACTGGAGTGGATGCTGGGCTATCTTGCT
CCCCCTTCCACTGTGGGTAGGGCCTTTCGCTTGTCCCATGGGCAGGTGGTGGGCCAAGGAGGAG
CTTAGCAAGTCTGCAGCCCAGCCCCACCTCCATAGGGTCCTGCAGGCCTGTGCTGAGAGGCCTG
GCGCTGCCTGGCAGAGTGACAAAGGCTCAGGACGGCTGGCTCTGGGGGACTCAGGCCAAACCCC
TTGGCACCATCCTGGCTTTTGGCAGGAATGAGTGAGGCCCTGCAGAGAGCATCCCAGGCCAAGG
TTCCCACTCAGCCTGCCCCCTCTGCATGTGGGTAGAGGATGTACTGGGACTTGGCATTTAGGAT
TCCATCTGGCCCAGCCCCTGAAGGTCCTGGGGAAGCAGGACTCAATTCTGAATAGCCAGTGGGG
CACACTGACTGTCCTCCCCAGGGGAACTGCAGCGCCCTCCTCCCCACTGCCCCCTGCAGCCCCT
GGGATATTTTGCTCACTATCCCTCCCCACTTGCTTCCCTGATATGTGCTCTGAGCTTCCCTGAA
CCAGGATCTGCCTATTACTGCTGTGCCCCATGGGGGGCTCCTTCCCTGCCTGAGGCACTGTTGC
AGAATGAAGTCACCTCGCCCCCCTCTTCCTTTAATCTTCAGGCCTCACTGGCCTGTCCTGCTCA
GCTTGGGCCAGTGACAATCTGCAAGGCTGAACAACAGCCCCTGGGGTTGAGGCCCCTGTGGCTC
CTGGTCAGGCTGCCCATTGTGGGGAGGGGCAGTGTTAGAGCAGGGCTGGTCATACCCTCTGGAG
TTCAGAGGAAGAGGTAGGACCAGTGCTTTTTTGTTTCTTTTGTTATTTTTGGTTGGGTGGGTGG
GAAGGTCTCTTTAAAATGGGGCAGGCCACACCCCCATTCCGTGCCTCAATTTCCCCATCTATAA
ACTGTAGATATGACTACTGACCTACCTCGCAGGGGGCTGTGGGGAGGCATAAGCTGATGTTTGT
AAAGCGCTTTGTAAATAAACGTGCTCTCTGAATGCCACAGA

hide sequence

RefSeq Acc Id:

XM_034959699 ⟹ XP_034815590

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,606,741 (-)	NCBI
NHGRI_mPanPan1	1	196,635,952 - 196,726,004 (-)	NCBI
Mhudiblu_PPA_v0	1	28,507,095 - 28,597,154 (+)	NCBI

RefSeq Acc Id:

XM_034959704 ⟹ XP_034815595

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,606,741 (-)	NCBI
NHGRI_mPanPan1	1	196,635,952 - 196,726,017 (-)	NCBI
Mhudiblu_PPA_v0	1	28,507,084 - 28,597,154 (+)	NCBI

RefSeq Acc Id:

XM_034959705 ⟹ XP_034815596

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,606,741 (-)	NCBI
NHGRI_mPanPan1	1	196,635,952 - 196,726,004 (-)	NCBI
Mhudiblu_PPA_v0	1	28,507,096 - 28,597,154 (+)	NCBI

RefSeq Acc Id:

XM_034959709 ⟹ XP_034815600

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,606,741 (-)	NCBI
NHGRI_mPanPan1	1	196,635,952 - 196,726,017 (-)	NCBI
Mhudiblu_PPA_v0	1	28,507,078 - 28,597,154 (+)	NCBI

RefSeq Acc Id:

XM_034959710 ⟹ XP_034815601

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,606,767 (-)	NCBI
NHGRI_mPanPan1	1	196,635,952 - 196,726,070 (-)	NCBI
Mhudiblu_PPA_v0	1	28,507,084 - 28,597,154 (+)	NCBI

RefSeq Acc Id:

XM_034959717 ⟹ XP_034815608

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,605,313 (-)	NCBI
NHGRI_mPanPan1	1	196,635,952 - 196,724,611 (-)	NCBI
Mhudiblu_PPA_v0	1	28,508,483 - 28,597,154 (+)	NCBI

RefSeq Acc Id:

XM_034959719 ⟹ XP_034815610

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,598,560 (-)	NCBI
NHGRI_mPanPan1	1	196,635,952 - 196,717,859 (-)	NCBI
Mhudiblu_PPA_v0	1	28,515,233 - 28,597,154 (+)	NCBI

RefSeq Acc Id:

XM_055095802 ⟹ XP_054951777

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,606,741 (-)	NCBI
NHGRI_mPanPan1	1	196,635,952 - 196,726,004 (-)	NCBI

RefSeq Acc Id:

XM_055095822 ⟹ XP_054951797

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,606,741 (-)	NCBI
NHGRI_mPanPan1	1	196,635,952 - 196,726,003 (-)	NCBI

RefSeq Acc Id:

XM_055095835 ⟹ XP_054951810

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,583,115 (-)	NCBI
NHGRI_mPanPan1	1	196,635,952 - 196,702,396 (-)	NCBI

RefSeq Acc Id:

XM_063593431 ⟹ XP_063449501

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	197,516,640 - 197,606,741 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_008951690	(Get FASTA)	NCBI Sequence Viewer
	XP_034815590	(Get FASTA)	NCBI Sequence Viewer
	XP_034815595	(Get FASTA)	NCBI Sequence Viewer
	XP_034815596	(Get FASTA)	NCBI Sequence Viewer
	XP_034815600	(Get FASTA)	NCBI Sequence Viewer
	XP_034815601	(Get FASTA)	NCBI Sequence Viewer
	XP_034815608	(Get FASTA)	NCBI Sequence Viewer
	XP_034815610	(Get FASTA)	NCBI Sequence Viewer
	XP_054951777	(Get FASTA)	NCBI Sequence Viewer
	XP_054951797	(Get FASTA)	NCBI Sequence Viewer
	XP_054951810	(Get FASTA)	NCBI Sequence Viewer
	XP_063449501	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000000527.1
	ENSPPAP00000000530.1

RefSeq Acc Id:	XP_008951690 ⟸ XM_008953442
- Peptide Label:	isoform X10
- UniProtKB:	A0A2R8Z6U7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRSDLGVGAGFEGDGQGQEPPTPIAPPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEIEYRMARG PWAEVHAVSLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLISRTKCAEPMRAPKGLAFA EIQARQLTLQWEPLGYNVTRCHTYTVSLCYHYTLGSSHNQTIRECVKTEQGVSRYTIKNLLPYR NVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGIAAESLTFTPLEDMIFLKWEEPQEPNGLITQYE ISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLHPGTTYLFSVRARTGKGFGQAALTEITT NISAPSFDYADMPSPLGESENTITVLLRPAQGRGAPISVYQVIVEEERARRLRREPGGQDCFPV PLTFEAALARGLVHYFGAELVASSLPEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAASHLK GETRLNCIRIARKAACKESKRPLEVSQRSEEMGLILGICAGGLAVLILLLGAIIVIIRKGRDHY AYSYYPKPVNMTKATVNYRQEKTHMMSAVDRSFTDQSTLQEDERLGLSFMDTHGYSTRGDQRSG GVTEASSLLGGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYESFFEGW DATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDIRINREGYHRSNHFIATQG PKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWPEDSDTYGDIKITLVKTETLAEYVV RTFALERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGR TGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGETTIPVS EFKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCL PFLISTDGDPNNYINAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSN SAWPCLQYWPEPGRQQYGLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLLVRHFQFLRWSAY RDTPDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFA AKTLRNYKPNMVETMDQYHFCYDVALEYLEGLESR hide sequence

RefSeq Acc Id:	XP_034815600 ⟸ XM_034959709
- Peptide Label:	isoform X6
- UniProtKB:	A0A2R8ZAN0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034815595 ⟸ XM_034959704
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R8Z6U7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034815601 ⟸ XM_034959710
- Peptide Label:	isoform X7
- UniProtKB:	A0A2R8ZAN0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034815590 ⟸ XM_034959699
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8Z6U7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034815596 ⟸ XM_034959705
- Peptide Label:	isoform X5
- UniProtKB:	A0A2R8ZAN0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034815608 ⟸ XM_034959717
- Peptide Label:	isoform X8
- UniProtKB:	A0A2R8Z6U7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034815610 ⟸ XM_034959719
- Peptide Label:	isoform X8
- UniProtKB:	A0A2R8Z6U7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSPPAP00000000527 ⟸ ENSPPAT00000002225

Ensembl Acc Id:

ENSPPAP00000000530 ⟸ ENSPPAT00000002228

RefSeq Acc Id:	XP_054951777 ⟸ XM_055095802
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R8Z6U7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054951797 ⟸ XM_055095822
- Peptide Label:	isoform X9
- UniProtKB:	A0A2R8ZAN0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054951810 ⟸ XM_055095835
- Peptide Label:	isoform X11
- UniProtKB:	A0A2R8ZAN0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063449501 ⟸ XM_063593431
- Peptide Label:	isoform X4
- UniProtKB:	A0A2R8Z6U7 (UniProtKB/TrEMBL)

Protein Domains

Fibronectin type-III MAM Tyrosine specific protein phosphatases Tyrosine-protein phosphatase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000001262	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000002225.1	UniProtKB/TrEMBL
	ENSPPAT00000002228.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.200	UniProtKB/TrEMBL
	2.60.40.10	UniProtKB/TrEMBL
	3.90.190.10	UniProtKB/TrEMBL
InterPro	ConA-like_dom_sf	UniProtKB/TrEMBL
	FN3_dom	UniProtKB/TrEMBL
	FN3_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	MAM_dom	UniProtKB/TrEMBL
	Prot-tyrosine_phosphatase-like	UniProtKB/TrEMBL
	PTPase_domain	UniProtKB/TrEMBL
	R-tyr_protein_phosphatases	UniProtKB/TrEMBL
	Tyr_Pase_AS	UniProtKB/TrEMBL
	Tyr_Pase_cat	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_dom	UniProtKB/TrEMBL
NCBI Gene	LOC100985291	ENTREZGENE
PANTHER	PROTEIN-TYROSINE-PHOSPHATASE-RELATED	UniProtKB/TrEMBL
	SUSHI DOMAIN-CONTAINING PROTEIN 1	UniProtKB/TrEMBL
Pfam	fn3	UniProtKB/TrEMBL
	MAM	UniProtKB/TrEMBL
	Y_phosphatase	UniProtKB/TrEMBL
PRINTS	MAMDOMAIN	UniProtKB/TrEMBL
	PRTYPHPHTASE	UniProtKB/TrEMBL
PROSITE	FN3	UniProtKB/TrEMBL
	MAM_1	UniProtKB/TrEMBL
	MAM_2	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_1	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_2	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_PTP	UniProtKB/TrEMBL
SMART	FN3	UniProtKB/TrEMBL
	MAM	UniProtKB/TrEMBL
	PTPc	UniProtKB/TrEMBL
	PTPc_motif	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49265	UniProtKB/TrEMBL
	SSF49899	UniProtKB/TrEMBL
	SSF52799	UniProtKB/TrEMBL
UniProt	A0A2R8Z6U7	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R8ZAN0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-07-01	PTPRU	protein tyrosine phosphatase receptor type U	LOC100985291	receptor-type tyrosine-protein phosphatase U	Symbol and/or name change	5135510	APPROVED
2020-06-11	LOC100985291	receptor-type tyrosine-protein phosphatase U	LOC103783254	receptor-type tyrosine-protein phosphatase U-like	Data merged from RGD:11944321	737654	PROVISIONAL
2020-06-11	LOC100985291	receptor-type tyrosine-protein phosphatase U	LOC100974128	receptor-type tyrosine-protein phosphatase U-like	Data merged from RGD:11899599	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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