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Gene: Tp73 (tumor protein p73) Rattus norvegicus
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Symbol: Tp73
Name: tumor protein p73
Description: Exhibits sequence-specific DNA binding activity. Involved in several processes, including activation of MAPK activity; positive regulation of apoptotic process; and regulation of neurogenesis. Localizes to the chromatin; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in breast cancer; lung cancer; nephroblastoma; and renal cell carcinoma. Orthologous to human TP73 (tumor protein p73); PARTICIPATES IN Ras mediated signaling pathway; altered p53 signaling pathway; measles pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 2-acetamidofluorene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: P73; transformation related protein 73; Trp73
Orthologs:
Homo sapiens (human) : TP73 (tumor protein p73)  HGNC  Alliance
Mus musculus (house mouse) : Trp73 (transformation related protein 73)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tp73 (tumor protein p73)
Pan paniscus (bonobo/pygmy chimpanzee) : TP73 (tumor protein p73)
Canis lupus familiaris (dog) : TP73 (tumor protein p73)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tp73 (tumor protein p73)
Sus scrofa (pig) : TP73 (tumor protein p73)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05171,355,876 - 171,415,354 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5171,355,876 - 171,415,354 (-)Ensembl
Rnor_5.05174,843,033 - 174,868,415 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.05174,889,051 - 174,901,875 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45170,848,979 - 171,078,739 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15170,861,458 - 170,885,614 (-)NCBI
Celera5162,833,132 - 162,892,871 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tp73
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307083
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.