Clcn6 (chloride voltage-gated channel 6) - Rat Genome Database

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Gene: Clcn6 (chloride voltage-gated channel 6) Rattus norvegicus
Analyze
Symbol: Clcn6
Name: chloride voltage-gated channel 6
RGD ID: 1305379
Description: Predicted to enable voltage-gated chloride channel activity. Involved in response to mechanical stimulus. Predicted to be located in membrane. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in coronary artery disease. Orthologous to human CLCN6 (chloride voltage-gated channel 6); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: chloride channel 6; chloride channel, voltage-sensitive 6; chloride transport protein 6; H(+)/Cl(-) exchange transporter 6; LOC295586
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Clcn6em2Mcwi  
Genetic Models: SS-Clcn6em2Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85163,715,593 - 163,748,301 (-)NCBIGRCr8
mRatBN7.25158,434,299 - 158,465,174 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5158,434,299 - 158,465,059 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5161,151,048 - 161,181,808 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05162,978,934 - 163,010,217 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05162,935,283 - 162,966,566 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05164,811,815 - 164,844,554 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,811,816 - 164,844,586 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05168,469,718 - 168,502,323 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45165,079,773 - 165,110,594 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15165,090,327 - 165,120,752 (-)NCBI
Celera5156,716,141 - 156,746,803 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Identifying multiple causative genes at a single GWAS locus. Flister MJ, etal., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Chloride channels and the reactions of cells to topography. Tobasnick G and Curtis AS, Eur Cell Mater. 2001 Dec 13;2:49-61.
7. The rs3737964 single-nucleotide polymorphism of the chloride channel-6 gene as a risk factor for coronary heart disease. Zhang L, etal., Mol Genet Genomic Med. 2015 Jul 14;3(6):537-42. doi: 10.1002/mgg3.163. eCollection 2015 Nov.
Additional References at PubMed
PMID:17897319   PMID:33390052   PMID:35927940  


Genomics

Comparative Map Data
Clcn6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85163,715,593 - 163,748,301 (-)NCBIGRCr8
mRatBN7.25158,434,299 - 158,465,174 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5158,434,299 - 158,465,059 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5161,151,048 - 161,181,808 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05162,978,934 - 163,010,217 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05162,935,283 - 162,966,566 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05164,811,815 - 164,844,554 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,811,816 - 164,844,586 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05168,469,718 - 168,502,323 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45165,079,773 - 165,110,594 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15165,090,327 - 165,120,752 (-)NCBI
Celera5156,716,141 - 156,746,803 (-)NCBICelera
Cytogenetic Map5q36NCBI
CLCN6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,806,191 - 11,843,130 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl111,806,096 - 11,848,079 (+)EnsemblGRCh38hg38GRCh38
GRCh37111,866,248 - 11,903,187 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,788,794 - 11,825,788 (+)NCBINCBI36Build 36hg18NCBI36
Celera110,979,829 - 11,016,824 (+)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef111,021,210 - 11,058,258 (+)NCBIHuRef
CHM1_1111,854,047 - 11,891,095 (+)NCBICHM1_1
T2T-CHM13v2.0111,350,275 - 11,387,211 (+)NCBIT2T-CHM13v2.0
Clcn6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394148,088,716 - 148,123,270 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4148,088,716 - 148,123,278 (-)EnsemblGRCm39 Ensembl
GRCm384148,004,259 - 148,038,813 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4148,004,259 - 148,038,821 (-)EnsemblGRCm38mm10GRCm38
MGSCv374147,380,593 - 147,412,876 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364146,850,284 - 146,882,567 (-)NCBIMGSCv36mm8
Celera4150,272,852 - 150,305,364 (-)NCBICelera
Cytogenetic Map4E1NCBI
cM Map478.67NCBI
Clcn6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554862,064,916 - 2,096,317 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554862,066,317 - 2,096,317 (-)NCBIChiLan1.0ChiLan1.0
CLCN6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21216,380,834 - 216,418,073 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11215,026,384 - 215,063,498 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0110,568,222 - 10,605,459 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1111,785,643 - 11,822,505 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,785,643 - 11,822,505 (+)Ensemblpanpan1.1panPan2
CLCN6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1284,410,740 - 84,443,874 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl284,413,612 - 84,445,033 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha280,943,970 - 80,978,766 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0285,075,630 - 85,110,501 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl285,075,631 - 85,108,811 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1281,824,232 - 81,859,027 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0282,824,152 - 82,858,937 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0283,886,934 - 83,921,795 (-)NCBIUU_Cfam_GSD_1.0
Clcn6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505834,813,213 - 34,844,601 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936474637,978 - 669,833 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936474637,930 - 669,383 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLCN6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl671,881,972 - 71,916,029 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1671,881,912 - 71,915,016 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2665,791,512 - 65,825,675 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CLCN6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120119,948,442 - 119,987,553 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20119,948,448 - 119,987,419 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605423,816,466 - 23,855,604 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Clcn6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248181,151,981 - 1,184,616 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248181,151,981 - 1,184,648 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Clcn6
185 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:136
Count of miRNA genes:103
Interacting mature miRNAs:118
Transcripts:ENSRNOT00000011287
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat


Genetic Models
This gene Clcn6 is modified in the following models/strains:
SS-Clcn6em2Mcwi    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000011287   ⟹   ENSRNOP00000011287
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5158,434,299 - 158,465,059 (-)Ensembl
Rnor_6.0 Ensembl5164,811,816 - 164,844,586 (-)Ensembl
RefSeq Acc Id: NM_001106479   ⟹   NP_001099949
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85163,717,439 - 163,748,198 (-)NCBI
mRatBN7.25158,434,299 - 158,465,059 (-)NCBI
Rnor_6.05164,813,662 - 164,844,421 (-)NCBI
Rnor_5.05168,469,718 - 168,502,323 (-)NCBI
RGSC_v3.45165,079,773 - 165,110,594 (-)RGD
Celera5156,716,141 - 156,746,803 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239378   ⟹   XP_006239440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85163,715,593 - 163,747,944 (-)NCBI
mRatBN7.25158,434,804 - 158,464,826 (-)NCBI
Rnor_6.05164,811,815 - 164,844,192 (-)NCBI
Rnor_5.05168,469,718 - 168,502,323 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109375   ⟹   XP_038965303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85163,722,509 - 163,748,301 (-)NCBI
mRatBN7.25158,439,370 - 158,465,174 (-)NCBI
RefSeq Acc Id: XM_039109377   ⟹   XP_038965305
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85163,715,593 - 163,729,510 (-)NCBI
mRatBN7.25158,434,804 - 158,446,373 (-)NCBI
RefSeq Acc Id: XR_592730
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85163,720,409 - 163,748,293 (-)NCBI
mRatBN7.25158,437,269 - 158,465,168 (-)NCBI
Rnor_6.05164,816,648 - 164,844,554 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001099949 (Get FASTA)   NCBI Sequence Viewer  
  XP_006239440 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965303 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965305 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL81090 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011287.6
RefSeq Acc Id: NP_001099949   ⟸   NM_001106479
- UniProtKB: D4A3H5 (UniProtKB/TrEMBL),   A6IU39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239440   ⟸   XM_006239378
- Peptide Label: isoform X1
- UniProtKB: D4A3H5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011287   ⟸   ENSRNOT00000011287
RefSeq Acc Id: XP_038965305   ⟸   XM_039109377
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038965303   ⟸   XM_039109375
- Peptide Label: isoform X2
Protein Domains
CBS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3H5-F1-model_v2 AlphaFold D4A3H5 1-870 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305379 AgrOrtholog
BioCyc Gene G2FUF-39200 BioCyc
Ensembl Genes ENSRNOG00000008345 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011287.7 UniProtKB/TrEMBL
Gene3D-CATH 3.10.580.10 UniProtKB/TrEMBL
  Clc chloride channel UniProtKB/TrEMBL
InterPro CBS_dom_sf UniProtKB/TrEMBL
  Cl-channel/antiporter UniProtKB/TrEMBL
  Cl-channel_core UniProtKB/TrEMBL
  Cl-channel_volt-gated UniProtKB/TrEMBL
  Cl_channel-6 UniProtKB/TrEMBL
  Cysta_beta_synth_core UniProtKB/TrEMBL
KEGG Report rno:295586 UniProtKB/TrEMBL
NCBI Gene 295586 ENTREZGENE
PANTHER CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER UniProtKB/TrEMBL
  H(+)_CL(-) EXCHANGE TRANSPORTER 6 UniProtKB/TrEMBL
Pfam CBS UniProtKB/TrEMBL
  Voltage_CLC UniProtKB/TrEMBL
PhenoGen Clcn6 PhenoGen
PRINTS CLCHANNEL UniProtKB/TrEMBL
  CLCHANNEL6 UniProtKB/TrEMBL
PROSITE CBS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008345 RatGTEx
SMART CBS UniProtKB/TrEMBL
Superfamily-SCOP Cl-channel_core UniProtKB/TrEMBL
  SSF54631 UniProtKB/TrEMBL
UniProt A6IU39 ENTREZGENE, UniProtKB/TrEMBL
  D4A3H5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Clcn6  chloride channel, voltage-sensitive 6  LOC680079  similar to Chloride channel protein 6 (ClC-6)  Data merged from RGD:1596809 1643240 APPROVED
2012-07-05 LOC680079  similar to Chloride channel protein 6 (ClC-6)  LOC680079  similar to Chloride channel protein 6 (ClC-6)  Gene reactivated at release of RGSC5.0 assembly 2298974 REACTIVATED
2008-04-30 Clcn6  chloride channel 6   Clcn6_predicted  chloride channel 6 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-20 LOC680079  similar to Chloride channel protein 6 (ClC-6)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Clcn6_predicted  chloride channel 6 (predicted)      Symbol and Name status set to approved 70820 APPROVED