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Gene: Cyp4a2 (cytochrome P450, family 4, subfamily a, polypeptide 2) Rattus norvegicus
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Symbol: Cyp4a2
Name: cytochrome P450, family 4, subfamily a, polypeptide 2
Description: Exhibits alkane 1-monooxygenase activity; arachidonic acid binding activity; and arachidonic acid monooxygenase activity. Involved in several processes, including fatty acid metabolic process; icosanoid biosynthetic process; and response to hormone. Localizes to the intracellular membrane-bounded organelle. Biomarker of autosomal recessive polycystic kidney disease; PARTICIPATES IN cytochrome P450 monooxygenase mediated pathway of arachidonic acid metabolism; linoleic acid metabolic pathway; arachidonic acid metabolic pathway; INTERACTS WITH (2-trans,6-trans)-farnesol; 1-naphthyl isothiocyanate; 2,2,2-tetramine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cyp4a11; CYPIVA2; cytochrome P-450 K-2; cytochrome P450 4A2; cytochrome P450 4A2-like; cytochrome P450 K-5; cytochrome P450, subfamily 4A, polypeptide 11; Cytochrome P450, subfamily IVA, polypeptide 11; cytochrome P450-LA-omega 2; lauric acid omega-hydroxylase; LOC100365231; long-chain fatty acid omega-monooxygenase; P-450 IV4AII; P-450 K-2; P450 K-5; P450-LA-omega 2
Orthologs:
No known orthologs. homologs ...
Allele / Splice: Cyp4a2em1Mcwi  
Genetic Models: SS-Chr 5BN-Cyp4a2em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05134,196,910 - 134,207,888 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05137,989,327 - 138,000,302 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45135,765,673 - 135,773,006 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15135,553,026 - 135,778,567 (-)NCBI
Cytogenetic Map5q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp4a2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2479
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.