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Gene: Ppt1 (palmitoyl-protein thioesterase 1) Rattus norvegicus
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Symbol: Ppt1
Name: palmitoyl-protein thioesterase 1
Description: Predicted to have palmitoyl-(protein) hydrolase activity and palmitoyl-CoA hydrolase activity. Predicted to be involved in several processes, including endocytosis; positive regulation of endocytosis; and protein catabolic process. Localizes to several cellular components, including the lysosome; neuronal cell body; and synaptic vesicle. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 1. Orthologous to human PPT1 (palmitoyl-protein thioesterase 1); PARTICIPATES IN fatty acid elongation pathway; INTERACTS WITH 3H-1,2-dithiole-3-thione; ammonium chloride; bexarotene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: palmitoyl-protein hydrolase 1; palmitoyl-protein thioesterase; Ppt; PPT-1
Orthologs:
Homo sapiens (human) : PPT1 (palmitoyl-protein thioesterase 1)  HGNC  Alliance
Mus musculus (house mouse) : Ppt1 (palmitoyl-protein thioesterase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppt1 (palmitoyl-protein thioesterase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PPT1 (palmitoyl-protein thioesterase 1)
Canis lupus familiaris (dog) : PPT1 (palmitoyl-protein thioesterase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppt1 (palmitoyl-protein thioesterase 1)
Sus scrofa (pig) : PPT1 (palmitoyl-protein thioesterase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05140,538,260 - 140,558,163 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5140,538,260 - 140,558,162 (+)Ensembl
Rnor_5.05144,329,263 - 144,349,162 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45142,153,498 - 142,173,401 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15142,158,725 - 142,179,598 (+)NCBI
Celera5133,659,813 - 133,679,711 (+)NCBICelera
Cytogenetic Map5q36NCBI
RH 3.4 Map5890.0RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ppt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61994
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.