Cnr2 (cannabinoid receptor 2) - Rat Genome Database

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Gene: Cnr2 (cannabinoid receptor 2) Rattus norvegicus
Analyze
Symbol: Cnr2
Name: cannabinoid receptor 2
RGD ID: 619713
Description: Exhibits cannabinoid receptor activity. Involved in several processes, including negative regulation of GABAergic synaptic transmission; negative regulation of mast cell activation; and negative regulation of nitric-oxide synthase activity. Localizes to dendrite; extrinsic component of cytoplasmic side of plasma membrane; and neuronal cell body. Used to study Huntington's disease; arthritis; and sciatic neuropathy. Biomarker of pancreatitis. Orthologous to human CNR2 (cannabinoid receptor 2); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cannabinoid receptor 2 (macrophage); cannabinoid receptor 2 gene; CB-2; CB2; CB2 receptor; CB2C; CNR2C; peripheral cannabinoid receptor; rCB2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25148,125,222 - 148,151,548 (+)NCBI
Rnor_6.0 Ensembl5154,260,062 - 154,268,126 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05154,242,010 - 154,268,126 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05158,006,539 - 158,032,977 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45154,674,754 - 154,702,552 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15154,709,561 - 154,712,096 (+)NCBI
Celera5146,533,227 - 146,558,688 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-arachidonoylglycerol  (ISO)
3',5'-cyclic AMP  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-Hydroxy-N-desmethyltamoxifen  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
actinomycin D  (ISO)
afimoxifene  (ISO)
ammonium chloride  (EXP)
anandamide  (EXP,ISO)
arachidonic acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
Cannabichromene  (ISO)
cannabidiol  (ISO)
cannabigerol  (ISO)
celastrol  (ISO)
citalopram  (EXP)
cobalt dichloride  (EXP)
cocaine  (ISO)
colforsin daropate hydrochloride  (ISO)
copper(II) sulfate  (ISO)
Delta(9)-tetrahydrocannabinolic acid  (ISO)
dextran sulfate  (ISO)
dibenzofuran  (ISO)
dioxygen  (EXP)
doxorubicin  (EXP)
fipronil  (EXP)
folic acid  (ISO)
gemcitabine  (ISO)
guanosine 5'-[gamma-thio]triphosphate  (ISO)
HU-308  (EXP,ISO)
hydrogen peroxide  (ISO)
Ibudilast  (EXP)
ibuprofen  (ISO)
imipramine  (EXP)
indazoles  (ISO)
indoles  (ISO)
Interferon beta-1b  (ISO)
L-ascorbic acid  (ISO)
lipopolysaccharide  (ISO)
mechlorethamine  (ISO)
medroxyprogesterone acetate  (ISO)
Methanandamide  (ISO)
methapyrilene  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nabilone  (EXP,ISO)
p-menthan-3-ol  (ISO)
paclitaxel  (EXP)
paeoniflorin  (EXP)
palmitoyl ethanolamide  (EXP,ISO)
paracetamol  (ISO)
paraquat  (EXP)
piperidines  (ISO)
poly(I:C)  (EXP)
pyrazoles  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quetiapine fumarate  (ISO)
ricinoleic acid  (ISO)
rimonabant  (ISO)
rotenone  (EXP)
sarin  (ISO)
SB 203580  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
SR 144528  (EXP,ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
WIN 55212-2  (EXP,ISO)

References

References - curated
1. Brown SM, etal., Biochim Biophys Acta 2002 Jul 19;1576(3):255-64.
2. Brusco A, etal., Synapse. 2008 Dec;62(12):944-9.
3. Carlisle SJ, etal., Int Immunopharmacol 2002 Jan;2(1):69-82.
4. Cella M, etal., Placenta. 2008 Aug;29(8):699-707. Epub 2008 Jun 18.
5. Chen L, etal., J Pain. 2009 Jul;10(7):732-9. Epub 2009 May 5.
6. Clayton N, etal., Pain 2002 Apr;96(3):253-60.
7. De Filippis D, etal., Br J Pharmacol. 2008 Aug;154(8):1672-9. Epub 2008 Jun 16.
8. Duncan M, etal., Am J Physiol Gastrointest Liver Physiol. 2008 Jul;295(1):G78-G87. Epub 2008 May 15.
9. Esposito G, etal., J Biol Chem 2002 Dec 27;277(52):50348-54.
10. Garcia-Ovejero D, etal., Neurobiol Dis. 2009 Jan;33(1):57-71. Epub 2008 Sep 30.
11. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
12. GOA data from the GO Consortium
13. Griffin G, etal., J Pharmacol Exp Ther 2000 Mar;292(3):886-94.
14. Hajrasouliha AR, etal., Eur J Pharmacol. 2008 Jan 28;579(1-3):246-52. Epub 2007 Oct 5.
15. Hu B, etal., Pain. 2009 Jun;143(3):206-12. Epub 2009 Apr 3.
16. Kurjak M, etal., Neuropeptides. 2008 Oct-Dec;42(5-6):623-32. Epub 2008 Oct 1.
17. Linari G, etal., Pharmacol Res. 2009 Mar;59(3):207-14. Epub 2008 Nov 27.
18. Lunn CA, etal., Immunopharmacol Immunotoxicol. 2007;29(3-4):387-401.
19. MGD data from the GO Consortium
20. Morgan NH, etal., Neuropharmacology. 2009 Sep;57(4):356-68. Epub 2009 Jul 16.
21. NCBI rat LocusLink and RefSeq merged data July 26, 2002
22. Onaivi ES, etal., Ann N Y Acad Sci. 2008 Oct;1139:434-49.
23. RGD automated data pipeline
24. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
25. RGD automated import pipeline for gene-chemical interactions
26. Sagredo O, etal., Glia. 2009 Aug 15;57(11):1154-67.
27. Torres E, etal., J Neurochem. 2010 Jan 12.
28. Zhang J, etal., Eur J Neurosci 2003 Jun;17(12):2750-4.
Additional References at PubMed
PMID:12477932   PMID:15277313   PMID:15317842   PMID:15525273   PMID:15728830   PMID:16356641   PMID:16472786   PMID:17045344   PMID:17356307   PMID:17499236   PMID:17545311   PMID:17585904  
PMID:18308297   PMID:18469844   PMID:18578993   PMID:18991892   PMID:19115376   PMID:19357281   PMID:19476641   PMID:19496827   PMID:19860893   PMID:20627823   PMID:20665820   PMID:20803619  
PMID:21443454   PMID:21486787   PMID:21595923   PMID:22198001   PMID:22331871   PMID:22366450   PMID:22490961   PMID:22532560   PMID:22683515   PMID:22791651   PMID:22795792   PMID:23081739  
PMID:23152849   PMID:23219970   PMID:23592773   PMID:23657829   PMID:23711022   PMID:23711495   PMID:23738526   PMID:24005231   PMID:24041123   PMID:24963491   PMID:25348153   PMID:25374096  
PMID:25504573   PMID:25894754   PMID:25895887   PMID:25963415   PMID:26470810   PMID:26833913   PMID:26880264   PMID:27013280   PMID:27261088   PMID:27285468   PMID:27769788   PMID:27935269  
PMID:28336953   PMID:28364261   PMID:28431968   PMID:28837063   PMID:28843453   PMID:28899427   PMID:29197803   PMID:29791076   PMID:30022523   PMID:30793435   PMID:31139184   PMID:31446615  
PMID:31472278   PMID:31697924   PMID:31894322   PMID:31981721   PMID:33809047  


Genomics

Comparative Map Data
Cnr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25148,125,222 - 148,151,548 (+)NCBI
Rnor_6.0 Ensembl5154,260,062 - 154,268,126 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05154,242,010 - 154,268,126 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05158,006,539 - 158,032,977 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45154,674,754 - 154,702,552 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15154,709,561 - 154,712,096 (+)NCBI
Celera5146,533,227 - 146,558,688 (+)NCBICelera
Cytogenetic Map5q36NCBI
CNR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl123,870,515 - 23,913,362 (-)EnsemblGRCh38hg38GRCh38
GRCh38123,870,515 - 23,913,362 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37124,197,005 - 24,239,852 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,073,047 - 24,112,404 (-)NCBINCBI36hg18NCBI36
Build 34123,945,765 - 23,985,123NCBI
Celera122,529,091 - 22,570,596 (-)NCBI
Cytogenetic Map1p36.11NCBI
HuRef122,452,107 - 22,493,123 (-)NCBIHuRef
CHM1_1124,313,205 - 24,352,708 (-)NCBICHM1_1
Cnr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394135,622,500 - 135,647,530 (+)NCBIGRCm39mm39
GRCm39 Ensembl4135,622,705 - 135,647,518 (+)Ensembl
GRCm384135,895,189 - 135,920,219 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4135,895,394 - 135,920,207 (+)EnsemblGRCm38mm10GRCm38
MGSCv374135,451,319 - 135,476,130 (+)NCBIGRCm37mm9NCBIm37
MGSCv364135,167,559 - 135,192,283 (+)NCBImm8
Celera4134,096,250 - 134,121,016 (+)NCBICelera
Cytogenetic Map4D3NCBI
Cnr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554523,763,742 - 3,795,069 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554523,763,742 - 3,795,069 (-)NCBIChiLan1.0ChiLan1.0
CNR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1124,046,009 - 24,135,236 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl124,050,008 - 24,051,090 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0123,066,153 - 23,108,065 (-)NCBIMhudiblu_PPA_v0panPan3
CNR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,640,636 - 75,662,000 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,658,999 - 75,660,126 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha272,229,153 - 72,230,280 (+)NCBI
ROS_Cfam_1.0276,199,651 - 76,221,314 (+)NCBI
UMICH_Zoey_3.1273,040,679 - 73,041,806 (+)NCBI
UNSW_CanFamBas_1.0274,047,309 - 74,048,436 (+)NCBI
UU_Cfam_GSD_1.0275,053,153 - 75,054,280 (+)NCBI
Cnr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505843,193,178 - 43,215,797 (-)NCBI
SpeTri2.0NW_0049364749,019,044 - 9,020,110 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl681,659,165 - 81,692,550 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1681,659,162 - 81,692,550 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2675,363,944 - 75,366,948 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNR2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120108,777,793 - 108,815,738 (+)NCBI
ChlSab1.1 Ensembl20108,813,579 - 108,814,661 (+)Ensembl
Vero_WHO_p1.0NW_0236660337,526,675 - 7,569,788 (-)NCBI
Cnr2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247648,388,375 - 8,422,961 (-)NCBI

Position Markers
D19S605  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25148,135,526 - 148,137,137 (+)MAPPER
Rnor_6.05154,252,110 - 154,253,720NCBIRnor6.0
Rnor_5.05158,016,579 - 158,018,189UniSTSRnor5.0
RGSC_v3.45154,685,273 - 154,686,883UniSTSRGSC3.4
Celera5146,542,955 - 146,544,565UniSTS
Cytogenetic Map5q36UniSTS
UniSTS:495964  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25148,149,222 - 148,149,430 (+)MAPPER
Rnor_6.05154,265,801 - 154,266,008NCBIRnor6.0
Rnor_5.05158,030,564 - 158,030,771UniSTSRnor5.0
RGSC_v3.45154,700,227 - 154,700,434UniSTSRGSC3.4
Celera5146,556,579 - 146,556,786UniSTS
Cytogenetic Map5q36UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540777918154732375Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)547745646167946134Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)561612600168109659Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)571552569157225114Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)584963058173504662Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5102945579154732228Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111278451156278451Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112279412157279412Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112279412157279412Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112279412157279412Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112279412157279412Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112279412157279412Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114140832159140832Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114140832159140832Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116767924161767924Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116767924161767924Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116767924161767924Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116767924161767924Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125455818157225114Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5128687766173687766Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5131077716173707219Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132551937173707219Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133943857173707219Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133943857173707219Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5134197905173707219Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5134502140157212422Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5134712342173707219Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5134712342173707219Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5136354114173707219Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136640731173707219Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138154677172402610Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5142307322173707219Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5142309061173707219Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149029982173687766Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5149568588167739697Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5149832180164807402Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5150340838164298744Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5150360936167946134Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:548
Count of miRNA genes:241
Interacting mature miRNAs:312
Transcripts:ENSRNOT00000012342, ENSRNOT00000074998
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 6 6 11 6 1
Low 43 51 35 8 35 4 4 62 35 41 10 4
Below cutoff 1 4 7 12 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001164142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001164143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_020543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC135901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF176350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF218846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF286721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF286722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC107941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ694960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ694961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JN420349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX494784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000012342   ⟹   ENSRNOP00000012342
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5154,265,097 - 154,268,126 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000074998   ⟹   ENSRNOP00000066697
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5154,260,062 - 154,268,124 (+)Ensembl
RefSeq Acc Id: NM_001164142   ⟹   NP_001157614
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25148,143,482 - 148,151,548 (+)NCBI
Rnor_6.05154,260,062 - 154,268,126 (+)NCBI
Rnor_5.05158,006,539 - 158,032,977 (+)NCBI
RGSC_v3.45154,674,754 - 154,702,552 (+)RGD
Celera5146,550,845 - 146,558,688 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001164143   ⟹   NP_001157615
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25148,125,629 - 148,151,548 (+)NCBI
Rnor_6.05154,242,214 - 154,268,126 (+)NCBI
Rnor_5.05158,006,539 - 158,032,977 (+)NCBI
RGSC_v3.45154,674,754 - 154,702,552 (+)RGD
Celera5146,533,227 - 146,558,688 (+)RGD
Sequence:
RefSeq Acc Id: NM_020543   ⟹   NP_065418
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25148,148,519 - 148,151,548 (+)NCBI
Rnor_6.05154,265,097 - 154,268,126 (+)NCBI
Rnor_5.05158,006,539 - 158,032,977 (+)NCBI
RGSC_v3.45154,674,754 - 154,702,552 (+)RGD
Celera5146,555,875 - 146,558,688 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593603   ⟹   XP_017449092
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05154,242,010 - 154,268,126 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039110686   ⟹   XP_038966614
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25148,142,964 - 148,151,548 (+)NCBI
RefSeq Acc Id: XM_039110687   ⟹   XP_038966615
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25148,125,224 - 148,151,548 (+)NCBI
RefSeq Acc Id: XM_039110688   ⟹   XP_038966616
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25148,125,224 - 148,151,548 (+)NCBI
RefSeq Acc Id: XM_039110689   ⟹   XP_038966617
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25148,125,222 - 148,151,548 (+)NCBI
RefSeq Acc Id: XM_039110690   ⟹   XP_038966618
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25148,142,951 - 148,151,053 (+)NCBI
RefSeq Acc Id: XR_005504534
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25148,142,964 - 148,150,872 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_065418   ⟸   NM_020543
- Peptide Label: isoform 2
- UniProtKB: Q9QZN9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001157615   ⟸   NM_001164143
- Peptide Label: isoform 1
- UniProtKB: Q9QZN9 (UniProtKB/Swiss-Prot),   C6G964 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157614   ⟸   NM_001164142
- Peptide Label: isoform 1
- UniProtKB: Q9QZN9 (UniProtKB/Swiss-Prot),   C6G964 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449092   ⟸   XM_017593603
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000012342   ⟸   ENSRNOT00000012342
RefSeq Acc Id: ENSRNOP00000066697   ⟸   ENSRNOT00000074998
RefSeq Acc Id: XP_038966617   ⟸   XM_039110689
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038966616   ⟸   XM_039110688
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038966615   ⟸   XM_039110687
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038966618   ⟸   XM_039110690
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038966614   ⟸   XM_039110686
- Peptide Label: isoform X1
Protein Domains
G_PROTEIN_RECEP_F1_2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694160
Promoter ID:EPDNEW_R4684
Type:single initiation site
Name:Cnr2_1
Description:cannabinoid receptor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05154,260,074 - 154,260,134EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619713 AgrOrtholog
Ensembl Genes ENSRNOG00000009260 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000012342 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000066697 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012342 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000074998 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Canbinoid_rcpt_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cnbnoid_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:57302 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 57302 ENTREZGENE
PANTHER PTHR22750:SF10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB CNR2 RGD
PhenoGen Cnr2 PhenoGen
PRINTS CANABINOID2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CANNABINOIDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt C6G964 ENTREZGENE, UniProtKB/TrEMBL
  CNR2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q9EP74 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-12 Cnr2  cannabinoid receptor 2  Cnr2  cannabinoid receptor 2 (macrophage)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-02-24 Cnr2  cannabinoid receptor 2 (macrophage)  Cnr2  cannabinoid receptor 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-02-01 Cnr2  cannabinoid receptor 2  Cnr2  cannabinoid receptor 2 (macrophage)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Cnr2  cannabinoid receptor 2 (macrophage)    cannabinoid receptor 2 gene  Name updated 1299863 APPROVED
2002-08-07 Cnr2  cannabinoid receptor 2 gene      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in activated peritoneal macrophages and microglia in brain cortex 632457
gene_homology has high homology to mouse and human homologs except for divergence in the carboxy terminal region, which is involved in regulation of receptor desensitization 632455
gene_homology aa sequence shares 93% identity with mouse Cnr2 and 81% with human CNR2 632458
gene_physical_interaction binds to adenylate cyclase 632458
gene_process may modulate nitrous oxide (NO) levels in CNS neurons 632454
gene_process may be involved with nociceptive pain and/or inflammatory hypersensitivity 632456
gene_process may be involved with nociceptive pain and/or inflammatory hypersensitivity 1299243
gene_process activates mitogen-activated protein (MAP) kinase 632455
gene_protein predicted protein contains 410 aa residues 632455
gene_regulation expression levels are modulated by cellular activation state 632457
gene_transcript contains 3 exons interrupted by 2 introns 632455