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Gene: Cnr2 (cannabinoid receptor 2) Rattus norvegicus
Symbol: Cnr2
Name: cannabinoid receptor 2
Description: Exhibits cannabinoid receptor activity. Involved in several processes, including negative regulation of GABAergic synaptic transmission; negative regulation of mast cell activation; and negative regulation of nitric-oxide synthase activity. Localizes to dendrite; extrinsic component of cytoplasmic side of plasma membrane; and neuronal cell body. Used to study Huntington's disease; arthritis; and sciatic neuropathy. Biomarker of pancreatitis. Orthologous to human CNR2 (cannabinoid receptor 2); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cannabinoid receptor 2 (macrophage); cannabinoid receptor 2 gene; CB-2; CB2; CB2 receptor; CB2C; CNR2C; peripheral cannabinoid receptor; rCB2
Homo sapiens (human) : CNR2 (cannabinoid receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Cnr2 (cannabinoid receptor 2 (macrophage))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cnr2 (cannabinoid receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CNR2 (cannabinoid receptor 2)
Canis lupus familiaris (dog) : CNR2 (cannabinoid receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cnr2 (cannabinoid receptor 2)
Sus scrofa (pig) : CNR2 (cannabinoid receptor 2)
Chlorocebus sabaeus (African green monkey) : CNR2 (cannabinoid receptor 2)
Heterocephalus glaber (naked mole-rat) : Cnr2 (cannabinoid receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05154,242,010 - 154,268,126 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5154,260,062 - 154,268,126 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05158,006,539 - 158,032,977 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45154,674,754 - 154,702,552 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15154,709,561 - 154,712,096 (+)NCBI
Celera5146,533,227 - 146,558,688 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cnr2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619713
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.