Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Plch2 (phospholipase C, eta 2) Rattus norvegicus
Symbol: Plch2
Name: phospholipase C, eta 2
Description: Predicted to have phosphatidylinositol phospholipase C activity. Predicted to be involved in several processes, including inositol trisphosphate biosynthetic process; phosphatidylinositol-mediated signaling; and release of sequestered calcium ion into cytosol. Predicted to localize to the plasma membrane. Orthologous to human PLCH2 (phospholipase C eta 2); INTERACTS WITH valproic acid; 2,2',4,4',5,5'-hexachlorobiphenyl (ortholog); 2,2',5,5'-tetrachlorobiphenyl (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2; LOC313756; RGD1304675; similar to FLJ00414 protein
Homo sapiens (human) : PLCH2 (phospholipase C eta 2)  HGNC  Alliance
Mus musculus (house mouse) : Plch2 (phospholipase C, eta 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plch2 (phospholipase C eta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCH2 (phospholipase C eta 2)
Canis lupus familiaris (dog) : PLCH2 (phospholipase C eta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plch2 (phospholipase C eta 2)
Sus scrofa (pig) : PLCH2 (phospholipase C eta 2)
Chlorocebus sabaeus (African green monkey) : PLCH2 (phospholipase C eta 2)
Heterocephalus glaber (naked mole-rat) : Plch2 (phospholipase C eta 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05172,386,400 - 172,455,965 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5172,388,598 - 172,424,081 (-)Ensembl
Rnor_5.05175,842,358 - 175,871,763 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45171,786,340 - 171,815,148 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15171,796,834 - 171,825,402 (-)NCBI
Celera5163,750,666 - 163,780,119 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Plch2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304675
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.