Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pla2g2a (phospholipase A2 group IIA) Rattus norvegicus
Symbol: Pla2g2a
Name: phospholipase A2 group IIA
Description: Exhibits calcium-dependent phospholipase A2 activity. Involved in phospholipid metabolic process. Localizes to perinuclear region of cytoplasm and secretory granule. Human ortholog(s) of this gene implicated in cholecystolithiasis; colorectal cancer; gastroesophageal reflux disease; and human immunodeficiency virus infectious disease. Orthologous to human PLA2G2A (phospholipase A2 group IIA); PARTICIPATES IN glypican signaling pathway; indometacin pharmacodynamics pathway; indometacin pharmacodynamics pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2-amino-2-deoxy-D-glucopyranose.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: eted enzyme type IIA phospholipase A2; GIIC sPLA2; group IIA phospholipase A2; phosphatidylcholine 2-acylhydrolase 2A; phospholipase A2, group IIA (platelets, synovial fluid); phospholipase A2, membrane associated; platelet phospholipase A2; sPLA2
Homo sapiens (human) : PLA2G2A (phospholipase A2 group IIA)  HGNC  Alliance
Mus musculus (house mouse) : Pla2g2a (phospholipase A2, group IIA (platelets, synovial fluid))  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : PLA2G2A (phospholipase A2 group IIA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pla2g2a (phospholipase A2 group IIA)
Sus scrofa (pig) : PLA2G2A (phospholipase A2 group IIA)
Chlorocebus sabaeus (African green monkey) : PLA2G2A (phospholipase A2 group IIA)
Heterocephalus glaber (naked mole-rat) : Pla2g2a (phospholipase A2 group IIA)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05157,282,650 - 157,285,295 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,282,669 - 157,285,328 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05161,024,039 - 161,026,650 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45157,654,786 - 157,657,360 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15157,664,332 - 157,667,400 (+)NCBI
Celera5149,464,001 - 149,466,577 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pla2g2a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620857
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.