Gene: Pla2g2a (phospholipase A2 group IIA) Rattus norvegicus
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Symbol: Pla2g2a
Name: phospholipase A2 group IIA
Description: ENCODES a protein that exhibits calcium-dependent phospholipase A2 activity; phospholipase A2 activity (ortholog); phospholipid binding (ortholog); INVOLVED IN phospholipid metabolic process; phosphatidic acid metabolic process (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN glypican signaling pathway; indometacin pharmacodynamics pathway; indometacin pharmacodynamics pathway; ASSOCIATED WITH Acute Lung Injury; Adrenal Insufficiency; Spinal Cord Injuries; FOUND IN perinuclear region of cytoplasm; secretory granule; endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose; 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: eted enzyme type IIA phospholipase A2; GIIC sPLA2; group IIA phospholipase A2; phosphatidylcholine 2-acylhydrolase 2A; phospholipase A2, group IIA (platelets, synovial fluid); phospholipase A2, membrane associated; platelet phospholipase A2; sPLA2
Orthologs:
Homo sapiens (human) : PLA2G2A (phospholipase A2 group IIA)  HGNC  Alliance
Mus musculus (house mouse) : Pla2g2a (phospholipase A2, group IIA (platelets, synovial fluid))  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : PLA2G2A (phospholipase A2 group IIA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pla2g2a (phospholipase A2 group IIA)
Sus scrofa (pig) : PLA2G2A (phospholipase A2 group IIA)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05157,282,650 - 157,285,295 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05161,024,039 - 161,026,650 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45157,654,786 - 157,657,360 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15157,664,332 - 157,667,400 (+)NCBI
Celera5149,464,001 - 149,466,577 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pla2g2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620857
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE