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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Kazn | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | KAZN (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KAZN mRNA | CTD | PMID:22079256 | Kazn | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Kazn (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of KAZN mRNA | CTD | PMID:36331819 | Kazn | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Kazn (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of KAZN mRNA | CTD | PMID:22206623 | Kazn | Rat | 17beta-estradiol | multiple interactions | ISO | KAZN (Homo sapiens) | 6480464 | [Estradiol binds to ESR2 protein] which results in increased expression of KAZN mRNA and [Estradiol co-treated with Progesterone] results in decreased expression of KAZN mRNA | CTD | PMID:20404318 and PMID:20660070 | Kazn | Rat | 17beta-estradiol | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | Estradiol results in increased expression of KAZN mRNA | CTD | PMID:23019147 more ... | Kazn | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Kazn (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of KAZN mRNA | CTD | PMID:26377647 | Kazn | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KAZN mRNA | CTD | PMID:33387578 | Kazn | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KAZN mRNA | CTD | PMID:32109520 | Kazn | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | KAZN (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of KAZN gene | CTD | PMID:31601247 | Kazn | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Kazn (Mus musculus) | 6480464 | bisphenol S affects the methylation of KAZN gene | CTD | PMID:31683443 | Kazn | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of KAZN mRNA | CTD | PMID:24780913 | Kazn | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of KAZN mRNA | CTD | PMID:31881176 | Kazn | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of KAZN mRNA | CTD | PMID:28959563 | Kazn | Rat | aflatoxin B1 | increases methylation | ISO | KAZN (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of KAZN gene | CTD | PMID:27153756 | Kazn | Rat | aflatoxin B1 | affects methylation | ISO | KAZN (Homo sapiens) | 6480464 | Aflatoxin B1 affects the methylation of KAZN intron | CTD | PMID:30157460 | Kazn | Rat | Aflatoxin B2 alpha | increases methylation | ISO | KAZN (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of KAZN intron | CTD | PMID:30157460 | Kazn | Rat | amphotericin B | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | Amphotericin B analog results in increased expression of KAZN mRNA | CTD | PMID:28534445 | Kazn | Rat | aristolochic acid A | decreases expression | ISO | KAZN (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of KAZN mRNA | CTD | PMID:33212167 | Kazn | Rat | arsane | affects methylation | ISO | KAZN (Homo sapiens) | 6480464 | Arsenic affects the methylation of KAZN gene | CTD | PMID:25304211 | Kazn | Rat | arsenic atom | affects methylation | ISO | KAZN (Homo sapiens) | 6480464 | Arsenic affects the methylation of KAZN gene | CTD | PMID:25304211 | Kazn | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of KAZN gene | CTD | PMID:35440735 | Kazn | Rat | benzo[a]pyrene | increases expression | ISO | Kazn (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of KAZN mRNA | CTD | PMID:32417428 | Kazn | Rat | benzo[a]pyrene | affects methylation | ISO | KAZN (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of KAZN intron | CTD | PMID:30157460 | Kazn | Rat | benzo[a]pyrene | decreases methylation | ISO | KAZN (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of KAZN promoter | CTD | PMID:27901495 | Kazn | Rat | benzo[b]fluoranthene | increases expression | ISO | Kazn (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of KAZN mRNA | CTD | PMID:26377693 | Kazn | Rat | benzo[e]pyrene | affects methylation | ISO | KAZN (Homo sapiens) | 6480464 | benzo(e)pyrene affects the methylation of KAZN intron | CTD | PMID:30157460 | Kazn | Rat | bisphenol A | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | bisphenol A results in increased expression of KAZN mRNA | CTD | PMID:23019147 and PMID:36828454 | Kazn | Rat | bisphenol A | decreases expression | ISO | KAZN (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of KAZN mRNA | CTD | PMID:36232920 | Kazn | Rat | bisphenol A | multiple interactions | ISO | KAZN (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of KAZN gene | CTD | PMID:31601247 | Kazn | Rat | bisphenol A | decreases methylation | ISO | Kazn (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of KAZN promoter | CTD | PMID:27312807 | Kazn | Rat | bisphenol A | increases methylation | ISO | Kazn (Mus musculus) | 6480464 | bisphenol A results in increased methylation of KAZN promoter | CTD | PMID:27312807 | Kazn | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of KAZN mRNA | CTD | PMID:25181051 | Kazn | Rat | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of KAZN protein | CTD | PMID:28903499 | Kazn | Rat | butanal | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of KAZN mRNA | CTD | PMID:26079696 | Kazn | Rat | caffeine | decreases phosphorylation | ISO | KAZN (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of KAZN protein | CTD | PMID:35688186 | Kazn | Rat | carbon nanotube | increases expression | ISO | Kazn (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Kazn | Rat | chlormequat chloride | increases expression | EXP | | 6480464 | Chlormequat results in increased expression of KAZN protein | CTD | PMID:34958886 | Kazn | Rat | clobetasol | decreases expression | ISO | Kazn (Mus musculus) | 6480464 | Clobetasol results in decreased expression of KAZN mRNA | CTD | PMID:27462272 | Kazn | Rat | copper(II) sulfate | decreases expression | ISO | KAZN (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of KAZN mRNA | CTD | PMID:19549813 | Kazn | Rat | cyclosporin A | decreases expression | ISO | KAZN (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of KAZN mRNA | CTD | PMID:25562108 | Kazn | Rat | dibenz[a,h]anthracene | increases expression | ISO | Kazn (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:26377693 | Kazn | Rat | Dibutyl phosphate | affects expression | ISO | KAZN (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of KAZN mRNA | CTD | PMID:37042841 | Kazn | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of KAZN mRNA | CTD | PMID:21266533 | Kazn | Rat | dicrotophos | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | dicrotophos results in increased expression of KAZN mRNA | CTD | PMID:28302478 | Kazn | Rat | doxorubicin | affects response to substance | ISO | KAZN (Homo sapiens) | 6480464 | KAZN protein affects the susceptibility to Doxorubicin | CTD | PMID:16217747 | Kazn | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of KAZN mRNA | CTD | PMID:29391264 | Kazn | Rat | ethanol | multiple interactions | ISO | Kazn (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of KAZN mRNA | CTD | PMID:30319688 | Kazn | Rat | ethanol | affects expression | ISO | Kazn (Mus musculus) | 6480464 | Ethanol affects the expression of KAZN mRNA | CTD | PMID:30319688 | Kazn | Rat | ethanol | affects splicing | ISO | Kazn (Mus musculus) | 6480464 | Ethanol affects the splicing of KAZN mRNA | CTD | PMID:30319688 | Kazn | Rat | folic acid | decreases expression | ISO | Kazn (Mus musculus) | 6480464 | Folic Acid results in decreased expression of KAZN mRNA | CTD | PMID:25629700 | Kazn | Rat | formaldehyde | decreases expression | ISO | KAZN (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of KAZN mRNA | CTD | PMID:20655997 | Kazn | Rat | FR900359 | affects phosphorylation | ISO | KAZN (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of KAZN protein | CTD | PMID:37730182 | Kazn | Rat | fulvestrant | multiple interactions | ISO | KAZN (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of KAZN gene | CTD | PMID:31601247 | Kazn | Rat | genistein | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | Genistein results in increased expression of KAZN mRNA | CTD | PMID:23019147 | Kazn | Rat | ketamine | increases expression | EXP | | 6480464 | Ketamine results in increased expression of KAZN mRNA | CTD | PMID:20080153 | Kazn | Rat | lipopolysaccharide | multiple interactions | ISO | KAZN (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of KAZN mRNA | CTD | PMID:35811015 | Kazn | Rat | malathion | decreases expression | ISO | KAZN (Homo sapiens) | 6480464 | Malathion results in decreased expression of KAZN mRNA | CTD | PMID:37047231 | Kazn | Rat | methapyrilene | affects methylation | ISO | KAZN (Homo sapiens) | 6480464 | Methapyrilene affects the methylation of KAZN intron | CTD | PMID:30157460 | Kazn | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of KAZN gene | CTD | PMID:35440735 | Kazn | Rat | methyl methanesulfonate | decreases expression | ISO | KAZN (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of KAZN mRNA | CTD | PMID:23649840 | Kazn | Rat | mitomycin C | affects response to substance | ISO | KAZN (Homo sapiens) | 6480464 | KAZN protein affects the susceptibility to Mitomycin | CTD | PMID:16217747 | Kazn | Rat | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | decreases expression | ISO | KAZN (Homo sapiens) | 6480464 | N more ... | CTD | PMID:12756304 | Kazn | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of KAZN gene | CTD | PMID:33148267 | Kazn | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Kazn (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of KAZN mRNA | CTD | PMID:37995155 | Kazn | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Kazn (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of KAZN mRNA | CTD | PMID:36331819 | Kazn | Rat | perfluorooctanoic acid | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of KAZN mRNA | CTD | PMID:36326898 | Kazn | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of KAZN gene | CTD | PMID:33148267 | Kazn | Rat | potassium chromate | decreases expression | ISO | KAZN (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of KAZN mRNA | CTD | PMID:22079256 | Kazn | Rat | potassium chromate | multiple interactions | ISO | KAZN (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KAZN mRNA | CTD | PMID:22079256 | Kazn | Rat | progesterone | multiple interactions | ISO | KAZN (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of KAZN mRNA | CTD | PMID:20660070 | Kazn | Rat | propanal | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of KAZN mRNA | CTD | PMID:26079696 | Kazn | Rat | quercetin | decreases expression | ISO | KAZN (Homo sapiens) | 6480464 | Quercetin results in decreased expression of KAZN mRNA | CTD | PMID:21632981 | Kazn | Rat | raloxifene | multiple interactions | ISO | KAZN (Homo sapiens) | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KAZN mRNA | CTD | PMID:19059307 | Kazn | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | KAZN (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of KAZN mRNA | CTD | PMID:35811015 | Kazn | Rat | sodium arsenite | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of KAZN mRNA and sodium arsenite results in increased expression of KAZN protein | CTD | PMID:21925251 and PMID:34032870 | Kazn | Rat | sodium arsenite | decreases expression | ISO | KAZN (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of KAZN mRNA | CTD | PMID:38568856 | Kazn | Rat | sodium arsenite | affects methylation | ISO | KAZN (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of KAZN gene | CTD | PMID:28589171 | Kazn | Rat | tamoxifen | multiple interactions | ISO | KAZN (Homo sapiens) | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in decreased expression of KAZN mRNA | CTD | PMID:19059307 | Kazn | Rat | tetraphene | increases expression | ISO | Kazn (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of KAZN mRNA | CTD | PMID:26377693 | Kazn | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of KAZN mRNA | CTD | PMID:33387578 | Kazn | Rat | trichostatin A | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | trichostatin A results in increased expression of KAZN mRNA | CTD | PMID:24935251 | Kazn | Rat | trimellitic anhydride | decreases expression | ISO | Kazn (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of KAZN mRNA | CTD | PMID:19042947 | Kazn | Rat | triphenyl phosphate | affects expression | ISO | KAZN (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of KAZN mRNA | CTD | PMID:37042841 | Kazn | Rat | uranium atom | affects expression | ISO | KAZN (Homo sapiens) | 6480464 | Uranium affects the expression of KAZN mRNA | CTD | PMID:15672453 | Kazn | Rat | valproic acid | affects expression | ISO | Kazn (Mus musculus) | 6480464 | Valproic Acid affects the expression of KAZN mRNA | CTD | PMID:17292431 | Kazn | Rat | valproic acid | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of KAZN mRNA | CTD | PMID:23179753 more ... | Kazn | Rat | vincaleukoblastine | affects response to substance | ISO | KAZN (Homo sapiens) | 6480464 | KAZN protein affects the susceptibility to Vinblastine | CTD | PMID:16217747 | Kazn | Rat | zearalenone | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | Zearalenone results in increased expression of KAZN mRNA | CTD | PMID:36828454 | Kazn | Rat | zinc sulfate | increases expression | ISO | KAZN (Homo sapiens) | 6480464 | Zinc Sulfate results in increased expression of KAZN mRNA | CTD | PMID:12756304 | |