Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ago3 (argonaute RISC catalytic component 3) Rattus norvegicus
Analyze
Symbol: Ago3
Name: argonaute RISC catalytic component 3
Description: Predicted to have RNA binding activity and endoribonuclease activity, cleaving miRNA-paired mRNA. Predicted to be involved in several processes, including RNA metabolic process; gene silencing by miRNA; and positive regulation of NIK/NF-kappaB signaling. Predicted to localize to several cellular components, including the RISC complex; RISC-loading complex; and nuclear lumen. Orthologous to human AGO3 (argonaute RISC catalytic component 3); PARTICIPATES IN microRNA pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: argonaute 3, RISC catalytic component; Eif2c3; eukaryotic translation initiation factor 2C, 3; LOC313593; protein argonaute-3
Orthologs:
Homo sapiens (human) : AGO3 (argonaute RISC catalytic component 3)  HGNC  Alliance
Mus musculus (house mouse) : Ago3 (argonaute RISC catalytic subunit 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago3 (argonaute RISC catalytic component 3)
Pan paniscus (bonobo/pygmy chimpanzee) : AGO3 (argonaute RISC catalytic component 3)
Canis lupus familiaris (dog) : AGO3 (argonaute RISC catalytic component 3)
Sus scrofa (pig) : AGO3 (argonaute RISC catalytic component 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05144,355,792 - 144,436,509 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5144,364,269 - 144,436,509 (-)Ensembl
Rnor_5.05148,131,514 - 148,203,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45145,713,438 - 145,779,165 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15145,722,862 - 145,796,791 (-)NCBI
Celera5137,138,867 - 137,210,660 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ago3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309163
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.