Ctps1 (CTP synthase 1) - Rat Genome Database

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Gene: Ctps1 (CTP synthase 1) Rattus norvegicus
Analyze
Symbol: Ctps1
Name: CTP synthase 1
RGD ID: 1311060
Description: Predicted to enable CTP synthase activity and identical protein binding activity. Predicted to be involved in lymphocyte proliferation and pyrimidine-containing compound biosynthetic process. Predicted to be active in cytoophidium and cytoplasm. Human ortholog(s) of this gene implicated in immunodeficiency 24. Orthologous to human CTPS1 (CTP synthase 1); PARTICIPATES IN beta-ureidopropionase deficiency pathway; de novo pyrimidine biosynthetic pathway; dihydropyrimidinase deficiency pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CTP synthase; Ctps; cytidine 5'-triphosphate synthase; LOC313560
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: RGD1562143  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25134,125,022 - 134,154,155 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5134,125,025 - 134,154,180 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5136,853,019 - 136,882,151 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05138,609,477 - 138,638,609 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05138,630,096 - 138,659,228 (-)NCBIRnor_WKY
Rnor_6.05139,475,934 - 139,505,065 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5139,475,934 - 139,505,065 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05143,259,189 - 143,288,320 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45141,136,686 - 141,165,817 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15141,141,913 - 141,189,364 (-)NCBI
Celera5132,680,893 - 132,710,010 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
2-butoxyethanol  (ISO)
3-chloropropane-1,2-diol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
aconitine  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
beauvericin  (ISO)
belinostat  (ISO)
benzalkonium chloride  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dioxygen  (ISO)
enniatin  (ISO)
enzyme inhibitor  (ISO)
fenpyroximate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glutathione  (EXP)
indole-3-methanol  (EXP)
ivermectin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
orphenadrine  (EXP)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
pentachlorophenol  (ISO)
phenobarbital  (ISO)
phosgene  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
theophylline  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tremolite asbestos  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
Triptolide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Identification of novel cellular targets in biliary tract cancers using global gene expression technology. Hansel DE, etal., Am J Pathol. 2003 Jul;163(1):217-29.
4. De novo synthesis of pyrimidine nucleotides; emerging interfaces with signal transduction pathways. Huang M and Graves LM, Cell Mol Life Sci. 2003 Feb;60(2):321-36.
5. Alteration of gene expression during nasopharyngeal carcinogenesis revealed by oligonucleotide microarray after microdissection of tumor tissue and normal epithelia from nasopharynx. Liu ZQ, etal., Chin Med J (Engl). 2009 Feb 20;122(4):437-43.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:16179339   PMID:19946888   PMID:24008161   PMID:24870241   PMID:25223282   PMID:25416956  


Genomics

Comparative Map Data
Ctps1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25134,125,022 - 134,154,155 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5134,125,025 - 134,154,180 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5136,853,019 - 136,882,151 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.05138,609,477 - 138,638,609 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.05138,630,096 - 138,659,228 (-)NCBIRnor_WKY
Rnor_6.05139,475,934 - 139,505,065 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5139,475,934 - 139,505,065 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05143,259,189 - 143,288,320 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45141,136,686 - 141,165,817 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15141,141,913 - 141,189,364 (-)NCBI
Celera5132,680,893 - 132,710,010 (-)NCBICelera
Cytogenetic Map5q36NCBI
CTPS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38140,979,696 - 41,012,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl140,979,300 - 41,012,565 (+)EnsemblGRCh38hg38GRCh38
GRCh37141,445,368 - 41,478,237 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36141,217,594 - 41,250,822 (+)NCBINCBI36Build 36hg18NCBI36
Build 34141,114,535 - 41,147,321NCBI
Celera139,727,935 - 39,761,156 (+)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef139,562,096 - 39,595,318 (+)NCBIHuRef
CHM1_1141,560,914 - 41,594,145 (+)NCBICHM1_1
T2T-CHM13v2.0140,849,069 - 40,881,929 (+)NCBIT2T-CHM13v2.0
Ctps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394120,397,065 - 120,427,473 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4120,397,065 - 120,427,473 (-)EnsemblGRCm39 Ensembl
GRCm384120,539,868 - 120,570,276 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4120,539,868 - 120,570,276 (-)EnsemblGRCm38mm10GRCm38
MGSCv374120,212,473 - 120,242,881 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364120,037,501 - 120,067,899 (-)NCBIMGSCv36mm8
Celera4119,256,495 - 119,286,990 (-)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map456.52NCBI
Ctps1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955537774,002 - 813,254 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955537773,664 - 811,084 (+)NCBIChiLan1.0ChiLan1.0
CTPS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1141,592,069 - 41,624,455 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl141,592,509 - 41,624,455 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0140,275,581 - 40,308,421 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CTPS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1152,067,767 - 2,093,014 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl152,067,763 - 2,093,014 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha152,326,992 - 2,356,330 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0152,158,160 - 2,187,539 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl152,158,162 - 2,187,530 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1152,063,812 - 2,093,145 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0152,123,983 - 2,153,311 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0152,139,372 - 2,168,710 (-)NCBIUU_Cfam_GSD_1.0
Ctps1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505856,777,925 - 56,808,428 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647422,602,800 - 22,633,169 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493647422,611,037 - 22,633,208 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTPS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6170,201,751 - 170,233,016 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16170,201,749 - 170,233,105 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26157,249,352 - 157,280,709 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CTPS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12091,905,452 - 91,938,188 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2091,901,771 - 91,937,819 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603324,943,247 - 24,976,031 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctps1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624892376,800 - 421,850 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ctps1
110 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:116
Count of miRNA genes:88
Interacting mature miRNAs:105
Transcripts:ENSRNOT00000013899
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5120740824143608494Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5125392826139989768Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5129132428143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat

Markers in Region
D5Got70  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25134,219,040 - 134,219,222 (+)MAPPERmRatBN7.2
Rnor_6.05139,569,942 - 139,570,123NCBIRnor6.0
Rnor_5.05143,351,318 - 143,351,499UniSTSRnor5.0
RGSC_v3.45141,230,451 - 141,230,633RGDRGSC3.4
RGSC_v3.45141,230,452 - 141,230,633UniSTSRGSC3.4
RGSC_v3.15141,235,678 - 141,235,859RGD
Celera5132,774,272 - 132,774,453UniSTS
RH 3.4 Map5876.9UniSTS
RH 3.4 Map5876.9RGD
RH 2.0 Map5876.2RGD
Cytogenetic Map5q36UniSTS
RH142657  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25134,149,908 - 134,150,107 (+)MAPPERmRatBN7.2
Rnor_6.05139,500,821 - 139,501,019NCBIRnor6.0
Rnor_5.05143,284,076 - 143,284,274UniSTSRnor5.0
RGSC_v3.45141,161,573 - 141,161,771UniSTSRGSC3.4
Celera5132,705,781 - 132,705,979UniSTS
RH 3.4 Map5902.4UniSTS
Cytogenetic Map5q36UniSTS
Ctps  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2102,343,957 - 2,344,033 (+)MAPPERmRatBN7.2
Rnor_6.0101,937,052 - 1,937,127NCBIRnor6.0
Rnor_5.010825,082 - 825,157UniSTSRnor5.0
RGSC_v3.4102,066,901 - 2,066,976UniSTSRGSC3.4
RGSC_v3.4101,303,184 - 1,303,259UniSTSRGSC3.4
Celera101,372,059 - 1,372,134UniSTS
Cytogenetic Map10q11UniSTS
Cytogenetic Map5q36UniSTS
BF408166  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25134,208,718 - 134,208,838 (+)MAPPERmRatBN7.2
Rnor_6.05139,559,621 - 139,559,740NCBIRnor6.0
Rnor_5.05143,341,056 - 143,341,175UniSTSRnor5.0
RGSC_v3.45141,219,730 - 141,219,849UniSTSRGSC3.4
Celera5132,764,029 - 132,764,148UniSTS
RH 3.4 Map5874.9UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 41 25 19 25 8 11 74 28 41 11 8
Low 16 16 16 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000013899   ⟹   ENSRNOP00000013899
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5134,125,025 - 134,154,180 (-)Ensembl
Rnor_6.0 Ensembl5139,475,934 - 139,505,065 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098430   ⟹   ENSRNOP00000083296
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5134,125,025 - 134,154,126 (-)Ensembl
RefSeq Acc Id: NM_001134873   ⟹   NP_001128345
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25134,125,022 - 134,154,155 (-)NCBI
Rnor_6.05139,475,934 - 139,505,065 (-)NCBI
Rnor_5.05143,259,189 - 143,288,320 (-)NCBI
RGSC_v3.45141,136,686 - 141,165,817 (-)RGD
Celera5132,680,893 - 132,710,010 (-)RGD
Sequence:
RefSeq Acc Id: XM_006238781   ⟹   XP_006238843
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25134,125,033 - 134,153,891 (-)NCBI
Rnor_6.05139,475,934 - 139,504,782 (-)NCBI
Rnor_5.05143,259,189 - 143,288,320 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001128345 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238843 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI61954 (Get FASTA)   NCBI Sequence Viewer  
  EDL80336 (Get FASTA)   NCBI Sequence Viewer  
  EDL80337 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001128345   ⟸   NM_001134873
- UniProtKB: B1WC02 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238843   ⟸   XM_006238781
- Peptide Label: isoform X1
- UniProtKB: B1WC02 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000013899   ⟸   ENSRNOT00000013899
RefSeq Acc Id: ENSRNOP00000083296   ⟸   ENSRNOT00000098430
Protein Domains
CTP_synth_N   GATase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1WC02-F1-model_v2 AlphaFold B1WC02 1-591 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693990
Promoter ID:EPDNEW_R4514
Type:initiation region
Name:Ctps1_1
Description:CTP synthase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05139,505,023 - 139,505,083EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311060 AgrOrtholog
BioCyc Gene G2FUF-40069 BioCyc
BioCyc Pathway CITRULBIO-PWY [L-citrulline biosynthesis] BioCyc
  GLUTAMINDEG-PWY [L-glutamine degradation I] BioCyc
  PWY-5921 [glutaminyl-tRNAgln biosynthesis via transamidation] BioCyc
  PWY-7176 [UTP and CTP de novo biosynthesis] BioCyc
  PWY-7185 [UTP and CTP dephosphorylation I] BioCyc
Ensembl Genes ENSRNOG00000009963 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000013899 ENTREZGENE
  ENSRNOP00000013899.5 UniProtKB/TrEMBL
  ENSRNOP00000083296.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013899 ENTREZGENE
  ENSRNOT00000013899.6 UniProtKB/TrEMBL
  ENSRNOT00000098430.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  3.40.50.880 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9027103 IMAGE-MGC_LOAD
InterPro Class_I_gatase-like UniProtKB/TrEMBL
  CTP_synthase UniProtKB/TrEMBL
  CTP_synthase_N UniProtKB/TrEMBL
  GATase1_CTP_Synthase UniProtKB/TrEMBL
  GATASE_1 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:313560 UniProtKB/TrEMBL
MGC_CLONE MGC:187755 IMAGE-MGC_LOAD
NCBI Gene 313560 ENTREZGENE
PANTHER PyrG_synth UniProtKB/TrEMBL
Pfam CTP_synth_N UniProtKB/TrEMBL
  GATase UniProtKB/TrEMBL
PhenoGen Ctps1 PhenoGen
Superfamily-SCOP SSF52317 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
TIGRFAMs PyrG UniProtKB/TrEMBL
UniProt A0A8I5ZZ52_RAT UniProtKB/TrEMBL
  B1WC02 ENTREZGENE, UniProtKB/TrEMBL
  F7F0L0_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-07-16 Ctps1  CTP synthase 1  Ctps  CTP synthase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Ctps  CTP synthase  Ctps  cytidine 5'-triphosphate synthase   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ctps  cytidine 5'-triphosphate synthase   Ctps_predicted  cytidine 5'-triphosphate synthase (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ctps_predicted  cytidine 5'-triphosphate synthase (predicted)      Symbol and Name status set to approved 70820 APPROVED