Ctps1 (CTP synthase 1) - Rat Genome Database

Name: Ctps1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Ctps1 (CTP synthase 1) Rattus norvegicus

Analyze

Symbol:

Ctps1

Name:

CTP synthase 1

RGD ID:

1311060

Description:

Predicted to enable CTP synthase activity and identical protein binding activity. Predicted to be involved in lymphocyte proliferation and pyrimidine-containing compound biosynthetic process. Predicted to be active in cytoophidium and cytoplasm. Human ortholog(s) of this gene implicated in immunodeficiency 24. Orthologous to human CTPS1 (CTP synthase 1); PARTICIPATES IN beta-ureidopropionase deficiency pathway; de novo pyrimidine biosynthetic pathway; dihydropyrimidinase deficiency pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CTP synthase; Ctps; cytidine 5'-triphosphate synthase; LOC313560

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CTPS1 (CTP synthase 1)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ctps (cytidine 5'-triphosphate synthase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ctps1 (CTP synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CTPS1 (CTP synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CTPS1 (CTP synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ctps1 (CTP synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CTPS1 (CTP synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CTPS1 (CTP synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ctps1 (CTP synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CTPS2 (CTP synthase 2)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	CTPS1 (CTP synthase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ctps (cytidine 5'-triphosphate synthase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ctps1a (CTP synthase 1a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ctps1b (CTP synthase 1b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CTPsyn	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	URA7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	URA8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ctps-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Related Pseudogenes:

RGD1562143

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	134,125,022 - 134,154,155 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	134,125,025 - 134,154,180 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	136,853,019 - 136,882,151 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	5	138,609,477 - 138,638,609 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	5	138,630,096 - 138,659,228 (-)	NCBI	Rnor_WKY
Rnor_6.0	5	139,475,934 - 139,505,065 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	139,475,934 - 139,505,065 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	143,259,189 - 143,288,320 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	141,136,686 - 141,165,817 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	141,141,913 - 141,189,364 (-)	NCBI
Celera	5	132,680,893 - 132,710,010 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

biliary tract benign neoplasm (ISO)

Charcot-Marie-Tooth disease dominant intermediate C (ISO)

immunodeficiency 24 (ISO)

Nasopharyngeal Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,6-tribromophenol (ISO)

2-butoxyethanol (ISO)

3-chloropropane-1,2-diol (EXP)

4-hydroxyphenyl retinamide (ISO)

5-fluorouracil (ISO)

aconitine (EXP)

acrolein (ISO)

acrylamide (EXP)

aflatoxin B1 (EXP,ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

antimycin A (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

atrazine (ISO)

beauvericin (ISO)

belinostat (ISO)

benzalkonium chloride (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

caffeine (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

coumarin (ISO)

coumestrol (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

deguelin (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

dichloroacetic acid (ISO)

diclofenac (ISO)

dioxygen (ISO)

enniatin (ISO)

enzyme inhibitor (ISO)

fenpyroximate (ISO)

flutamide (EXP)

folic acid (ISO)

furan (EXP)

genistein (ISO)

gentamycin (EXP)

glafenine (EXP)

glutathione (EXP)

indole-3-methanol (EXP)

ivermectin (ISO)

L-methionine (ISO)

lead diacetate (ISO)

lipopolysaccharide (ISO)

menadione (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

orphenadrine (EXP)

ozone (ISO)

paracetamol (EXP)

paraquat (EXP)

pentachlorophenol (ISO)

phenobarbital (ISO)

phosgene (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

propanal (ISO)

propiconazole (ISO)

quercetin (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

tamoxifen (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (ISO)

theophylline (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

tremolite asbestos (ISO)

trichostatin A (ISO)

trimellitic anhydride (ISO)

Triptolide (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

'de novo' CTP biosynthetic process (IEA)

B cell proliferation (ISO)

biological_process (ND)

CTP biosynthetic process (IBA,ISO)

glutamine metabolic process (IEA)

pyrimidine nucleobase biosynthetic process (IBA)

T cell proliferation (ISO)

Cellular Component

cellular_component (ND)

cytoophidium (IBA,ISO)

cytoplasm (IBA)

Molecular Function

ATP binding (IEA)

CTP synthase activity (IBA,ISO)

identical protein binding (IBA,ISO)

molecular_function (ND)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

beta-ureidopropionase deficiency pathway (ISO)

de novo pyrimidine biosynthetic pathway (ISO)

dihydropyrimidinase deficiency pathway (ISO)

gemcitabine pharmacodynamics pathway (ISO)

gemcitabine pharmacokinetics pathway (ISO)

mitochondrial neurogastrointestinal encephalopathy syndrome pathway (ISO)

orotic aciduria 1 pathway (ISO)

pyrimidine metabolic pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Identification of novel cellular targets in biliary tract cancers using global gene expression technology.	Hansel DE, etal., Am J Pathol. 2003 Jul;163(1):217-29.
4.	De novo synthesis of pyrimidine nucleotides; emerging interfaces with signal transduction pathways.	Huang M and Graves LM, Cell Mol Life Sci. 2003 Feb;60(2):321-36.
5.	Alteration of gene expression during nasopharyngeal carcinogenesis revealed by oligonucleotide microarray after microdissection of tumor tissue and normal epithelia from nasopharynx.	Liu ZQ, etal., Chin Med J (Engl). 2009 Feb 20;122(4):437-43.
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:16179339	PMID:19946888	PMID:24008161	PMID:24870241	PMID:25223282	PMID:25416956

Genomics

Comparative Map Data

Ctps1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	134,125,022 - 134,154,155 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	134,125,025 - 134,154,180 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	136,853,019 - 136,882,151 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	5	138,609,477 - 138,638,609 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	5	138,630,096 - 138,659,228 (-)	NCBI	Rnor_WKY
Rnor_6.0	5	139,475,934 - 139,505,065 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	139,475,934 - 139,505,065 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	143,259,189 - 143,288,320 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	141,136,686 - 141,165,817 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	141,141,913 - 141,189,364 (-)	NCBI
Celera	5	132,680,893 - 132,710,010 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

CTPS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	40,979,696 - 41,012,565 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	1	40,979,300 - 41,012,565 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	41,445,368 - 41,478,237 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	41,217,594 - 41,250,822 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	41,114,535 - 41,147,321	NCBI
Celera	1	39,727,935 - 39,761,156 (+)	NCBI		Celera
Cytogenetic Map	1	p34.2	NCBI
HuRef	1	39,562,096 - 39,595,318 (+)	NCBI		HuRef
CHM1_1	1	41,560,914 - 41,594,145 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	40,849,069 - 40,881,929 (+)	NCBI		T2T-CHM13v2.0

Ctps
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	120,397,065 - 120,427,473 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	120,397,065 - 120,427,473 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	120,539,868 - 120,570,276 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	120,539,868 - 120,570,276 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	120,212,473 - 120,242,881 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	120,037,501 - 120,067,899 (-)	NCBI		MGSCv36	mm8
Celera	4	119,256,495 - 119,286,990 (-)	NCBI		Celera
Cytogenetic Map	4	D2.1	NCBI
cM Map	4	56.52	NCBI

Ctps1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955537	774,002 - 813,254 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955537	773,664 - 811,084 (+)	NCBI	ChiLan1.0	ChiLan1.0

CTPS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	41,592,069 - 41,624,455 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	41,592,509 - 41,624,455 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	40,275,581 - 40,308,421 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

CTPS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	2,067,767 - 2,093,014 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	2,067,763 - 2,093,014 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	2,326,992 - 2,356,330 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	2,158,160 - 2,187,539 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	2,158,162 - 2,187,530 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	2,063,812 - 2,093,145 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	2,123,983 - 2,153,311 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	2,139,372 - 2,168,710 (-)	NCBI		UU_Cfam_GSD_1.0

Ctps1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	56,777,925 - 56,808,428 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	22,602,800 - 22,633,169 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936474	22,611,037 - 22,633,208 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CTPS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	170,201,751 - 170,233,016 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	170,201,749 - 170,233,105 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	157,249,352 - 157,280,709 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CTPS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	91,905,452 - 91,938,188 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	91,901,771 - 91,937,819 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	24,943,247 - 24,976,031 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ctps1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624892	376,800 - 421,850 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ctps1
110 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	116
Count of miRNA genes:	88
Interacting mature miRNAs:	105
Transcripts:	ENSRNOT00000013899
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	59793399	143070159	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
631527	Tls1	T-lymphoma susceptibility QTL 1	0	0.001	thymus integrity trait (VT:0010555)	post-insult time to onset of T-cell lymphoma (CMO:0001907)	5	90450144	135450144	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	94858972	143070159	Rat
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	97059760	147465714	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	97570330	136479578	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	120740824	143608494	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	120740824	151018848	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
1300122	Wbc1	White blood cell count QTL 1	2.75		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	5	125392826	139989768	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	129132428	143070159	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	129132447	151006154	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat

Markers in Region

D5Got70

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	134,219,040 - 134,219,222 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	139,569,942 - 139,570,123	NCBI	Rnor6.0
Rnor_5.0	5	143,351,318 - 143,351,499	UniSTS	Rnor5.0
RGSC_v3.4	5	141,230,451 - 141,230,633	RGD	RGSC3.4
RGSC_v3.4	5	141,230,452 - 141,230,633	UniSTS	RGSC3.4
RGSC_v3.1	5	141,235,678 - 141,235,859	RGD
Celera	5	132,774,272 - 132,774,453	UniSTS
RH 3.4 Map	5	876.9	UniSTS
RH 3.4 Map	5	876.9	RGD
RH 2.0 Map	5	876.2	RGD
Cytogenetic Map	5	q36	UniSTS

RH142657

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	134,149,908 - 134,150,107 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	139,500,821 - 139,501,019	NCBI	Rnor6.0
Rnor_5.0	5	143,284,076 - 143,284,274	UniSTS	Rnor5.0
RGSC_v3.4	5	141,161,573 - 141,161,771	UniSTS	RGSC3.4
Celera	5	132,705,781 - 132,705,979	UniSTS
RH 3.4 Map	5	902.4	UniSTS
Cytogenetic Map	5	q36	UniSTS

Ctps

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	2,343,957 - 2,344,033 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	1,937,052 - 1,937,127	NCBI	Rnor6.0
Rnor_5.0	10	825,082 - 825,157	UniSTS	Rnor5.0
RGSC_v3.4	10	2,066,901 - 2,066,976	UniSTS	RGSC3.4
RGSC_v3.4	10	1,303,184 - 1,303,259	UniSTS	RGSC3.4
Celera	10	1,372,059 - 1,372,134	UniSTS
Cytogenetic Map	10	q11	UniSTS
Cytogenetic Map	5	q36	UniSTS

BF408166

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	134,208,718 - 134,208,838 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	139,559,621 - 139,559,740	NCBI	Rnor6.0
Rnor_5.0	5	143,341,056 - 143,341,175	UniSTS	Rnor5.0
RGSC_v3.4	5	141,219,730 - 141,219,849	UniSTS	RGSC3.4
Celera	5	132,764,029 - 132,764,148	UniSTS
RH 3.4 Map	5	874.9	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	41	25	19	25	8	11	74	28	41	11	8
Low			16	16		16				7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001134873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238781	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC129237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC161954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ210258	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000013899 ⟹ ENSRNOP00000013899

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	134,125,025 - 134,154,180 (-)	Ensembl
Rnor_6.0 Ensembl	5	139,475,934 - 139,505,065 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000098430 ⟹ ENSRNOP00000083296

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	134,125,025 - 134,154,126 (-)	Ensembl

RefSeq Acc Id:

NM_001134873 ⟹ NP_001128345

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	134,125,022 - 134,154,155 (-)	NCBI
Rnor_6.0	5	139,475,934 - 139,505,065 (-)	NCBI
Rnor_5.0	5	143,259,189 - 143,288,320 (-)	NCBI
RGSC_v3.4	5	141,136,686 - 141,165,817 (-)	RGD
Celera	5	132,680,893 - 132,710,010 (-)	RGD

Sequence:

show sequence

CGCCTCTCAGAAAGACGGCTGGCGCATGCGGCCCGGCTGAGCACTGGCTCCGCGAGCCTCACCG
CGCGCGCGTCGGCCTTGCTGTGGCTGACACGAGACTCTGAAGCCGGCTCCAGGTTAAAAGAAAA
ATGAAGTACATTCTAGTTACTGGTGGTGTTATATCAGGAATTGGAAAAGGAGTTATCGCCAGCA
GTGTGGGCACAATACTCAAGTCATGCGGTTTACATGTAACGTCAATTAAAATTGACCCCTATAT
TAACATCGATGCAGGAACATTCTCTCCTTATGAACATGGAGAAGTCTTTGTGCTGGATGATGGT
GGAGAAGTTGACCTTGACTTGGGAAACTATGAGCGGTTCCTTGATATCCGCCTCACCAAGGACA
ATAACCTGACCACAGGGAAGATATACCAGTACGTCATTAACAAGGAGCGCAAAGGAGATTACTT
AGGGAAAACTGTTCAGGTTGTCCCTCACATCACAGATGCAATTCAAGAGTGGGTGATGAGACAG
GCGTTAATACCTGTAGACGAAGATGGCTTAGAACCTCAAGTGTGTGTTATTGAGCTTGGTGGCA
CAGTGGGAGACATTGAAAGCATGCCCTTCATTGAGGCCTTCCGCCAGTTCCAGTTCAAGGTCAA
GAAGGAGAACTTTTGTAATATCCATGTCAGTCTGGTTCCTCAGCCAAGTTCAACAGGGGAACAG
AAGACAAAACCCACTCAGAACAGTGTTCGGGAACTTAGAGGACTCGGGCTGTCTCCAGACTTAG
TGGTGTGCAGATGCTCAAATCCTCTTGACACATCTGTGAAAGAGAAAATATCAATGTTCTGCCA
TGTGGAACCTGAACAAGTGATCTGCGTTCACGACGTCTCATCCATCTACCGGGTGCCCTTGCTG
TTAGAAGAGCAAGGGGTGGTGGACTACTTTCTTCGGAGACTCGACCTTCCCGTTGAGAGACAGT
CACGGAAGATGCTGATGAAGTGGAAGGAGATGGCAGACAGATATGATCGCTTGCTGGAGACCTG
CTCTATCGCTCTTGTGGGCAAATACACCAAATTCTCAGATTCGTATGCCTCTGTCATTAAAGCT
CTAGAGCACTCTGCATTGGCTATTAACCACAAGTTGGAGATCAAGTACATCGATTCCACAGACC
TGGAGCCGAGCACCCTGCAGGAAGAGCCTGTGCGCTACCATGAGGCCTGGCAGAAGCTCTGCAG
TGCTCATGGAGTGCTGGTTCCAGGAGGATTTGGTGTTCGGGGAACAGAAGGGAAAATTCAAGCA
ATTGCCTGGGCTCGGAAACAGAAGAAGCCTTTTTTGGGTGTGTGCTTAGGAATGCAGCTAGCAG
TGGTAGAATTTTCAAGAAATGTGCTGGGATGGCAAGATGCCAATTCTACAGAGTTTGACCCTAA
GACTAGTCATCCTGTGGTCATAGACATGCCAGAGCATAACCCTGGGCAAATGGGAGGAACCATG
AGGCTGGGCAAGAGGAGAACCCTGTTCCAGACCAAGAACTCAGTCATGAGGAAACTCTATGGAG
ACACAGACTACTTGGAAGAAAGGCACCGCCACCGATTTGAGGTGAATCCAGTCCTGAAAAAGTG
CTTGGAAGAGCAAGGCTTGAAGTTTGTTGGCCAGGATGTTGAAGGCGAGAGGATGGAGATCGTG
GAGCTGGAAGACCATCCGTTTTTCGTTGGAGTGCAGTATCACCCCGAGTTCCTGTCCAGGCCAA
TCAAGCCCTCCCCACCCTACTTTGGCCTCCTCCTGGCCTCTGTGGGGCGGCTCCCACATTACCT
TCAGAAAGGTTGCCGGCTGTCACCCAGGGACACTTACAGTGACAGAAGTGGGAGCAGCTCCCCT
GACTCTGAAATCACTGAACTGAAGTTTCCATCAATAAGTCAGGACTGATCTGGATGATTCTTCA
AGAAAGCTTTCAACTTTTGATAGTTTATAACTATGATTTTACACCCTGGCTTTTGACACTTCTT
TTAAATTATGTTTTTATTAAGATTATTTTATTATGGGGGAAAGGCATTTGGAAAACTTTGTCAC
TTGCATGTTCCGTCATTTATACTGGATCCTGCAACACATGTATTTGTGCCACAATACCTTTGCA
GTTTGTGTGCTTCTACGATAGGAAGCAGGACTCTGGAGGGGACCTGATGGTGGCCACTGGCTGG
ATATCAACCTTGCTTTTCCAACCACTTGGGTCACGGTCATTGGAATGAATTGCTGTTATTTCCC
TGGGGTGCCAGGACTCCAGTGCTGGGCTGTAACTGGGTGTTGCTGGGGTCTCAGTGCTGCTGAG
CTTTAGGGGACTAGATGCCAGCCATGGTTGCCCTCACCATCCAGAGGGCTGTTTGGTTCTTTGG
CACATCAGGCAAGCTGTGTCTGTATAAAGTGTCACATAAAAACCCTGGGTCTCTGGCTACACTT
TCAGTTCCTGGGGCTGAGAAAACTCCTTGCATCAAGGGGTCAAGAAACAAGGAATTTTAGGGTA
ACTGGTTCTAAAGCCCTCTCTTGTGTGTGCACATTGATTTGAGGGTATGTTTTCTTCAGAATGG
TGTTAGTGCAGTTGAGATGCAATTTGAAGTTATTTTCTTAATGTGACATAGCCATGGGCATGGC
CATGTGCGTACAATATGGTGGCTGACTTGATGTATACTCCTAACTTAATAAATAATGTGCAACC
ATC

hide sequence

RefSeq Acc Id:

XM_006238781 ⟹ XP_006238843

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	134,125,033 - 134,153,891 (-)	NCBI
Rnor_6.0	5	139,475,934 - 139,504,782 (-)	NCBI
Rnor_5.0	5	143,259,189 - 143,288,320 (-)	NCBI

Sequence:

show sequence

GGAGTGGGGCGGGCAGTCCCGGAACGCGAGGTGCCGGCTCCCGCGCGCCGGCCGCGTGGCCCGG
CTGAGGAGAGGGGCCGAGTCGGGCGGCGCCGGCAGCCGGACTTGGTTAAAAGAAAAATGAAGTA
CATTCTAGTTACTGGTGGTGTTATATCAGGAATTGGAAAAGGAGTTATCGCCAGCAGTGTGGGC
ACAATACTCAAGTCATGCGGTTTACATGTAACGTCAATTAAAATTGACCCCTATATTAACATCG
ATGCAGGAACATTCTCTCCTTATGAACATGGAGAAGTCTTTGTGCTGGATGATGGTGGAGAAGT
TGACCTTGACTTGGGAAACTATGAGCGGTTCCTTGATATCCGCCTCACCAAGGACAATAACCTG
ACCACAGGGAAGATATACCAGTACGTCATTAACAAGGAGCGCAAAGGAGATTACTTAGGGAAAA
CTGTTCAGGTTGTCCCTCACATCACAGATGCAATTCAAGAGTGGGTGATGAGACAGGCGTTAAT
ACCTGTAGACGAAGATGGCTTAGAACCTCAAGTGTGTGTTATTGAGCTTGGTGGCACAGTGGGA
GACATTGAAAGCATGCCCTTCATTGAGGCCTTCCGCCAGTTCCAGTTCAAGGTCAAGAAGGAGA
ACTTTTGTAATATCCATGTCAGTCTGGTTCCTCAGCCAAGTTCAACAGGGGAACAGAAGACAAA
ACCCACTCAGAACAGTGTTCGGGAACTTAGAGGACTCGGGCTGTCTCCAGACTTAGTGGTGTGC
AGATGCTCAAATCCTCTTGACACATCTGTGAAAGAGAAAATATCAATGTTCTGCCATGTGGAAC
CTGAACAAGTGATCTGCGTTCACGACGTCTCATCCATCTACCGGGTGCCCTTGCTGTTAGAAGA
GCAAGGGGTGGTGGACTACTTTCTTCGGAGACTCGACCTTCCCGTTGAGAGACAGTCACGGAAG
ATGCTGATGAAGTGGAAGGAGATGGCAGACAGATATGATCGCTTGCTGGAGACCTGCTCTATCG
CTCTTGTGGGCAAATACACCAAATTCTCAGATTCGTATGCCTCTGTCATTAAAGCTCTAGAGCA
CTCTGCATTGGCTATTAACCACAAGTTGGAGATCAAGTACATCGATTCCACAGACCTGGAGCCG
AGCACCCTGCAGGAAGAGCCTGTGCGCTACCATGAGGCCTGGCAGAAGCTCTGCAGTGCTCATG
GAGTGCTGGTTCCAGGAGGATTTGGTGTTCGGGGAACAGAAGGGAAAATTCAAGCAATTGCCTG
GGCTCGGAAACAGAAGAAGCCTTTTTTGGGTGTGTGCTTAGGAATGCAGCTAGCAGTGGTAGAA
TTTTCAAGAAATGTGCTGGGATGGCAAGATGCCAATTCTACAGAGTTTGACCCTAAGACTAGTC
ATCCTGTGGTCATAGACATGCCAGAGCATAACCCTGGGCAAATGGGAGGAACCATGAGGCTGGG
CAAGAGGAGAACCCTGTTCCAGACCAAGAACTCAGTCATGAGGAAACTCTATGGAGACACAGAC
TACTTGGAAGAAAGGCACCGCCACCGATTTGAGGTGAATCCAGTCCTGAAAAAGTGCTTGGAAG
AGCAAGGCTTGAAGTTTGTTGGCCAGGATGTTGAAGGCGAGAGGATGGAGATCGTGGAGCTGGA
AGACCATCCGTTTTTCGTTGGAGTGCAGTATCACCCCGAGTTCCTGTCCAGGCCAATCAAGCCC
TCCCCACCCTACTTTGGCCTCCTCCTGGCCTCTGTGGGGCGGCTCCCACATTACCTTCAGAAAG
GTTGCCGGCTGTCACCCAGGGACACTTACAGTGACAGAAGTGGGAGCAGCTCCCCTGACTCTGA
AATCACTGAACTGAAGTTTCCATCAATAAGTCAGGACTGATCTGGATGATTCTTCAAGAAAGCT
TTCAACTTTTGATAGTTTATAACTATGATTTTACACCCTGGCTTTTGACACTTCTTTTAAATTA
TGTTTTTATTAAGATTATTTTATTATGGGGGAAAGGCATTTGGAAAACTTTGTCACTTGCATGT
TCCGTCATTTATACTGGATCCTGCAACACATGTATTTGTGCCACAATACCTTTGCAGTTTGTGT
GCTTCTACGATAGGAAGCAGGACTCTGGAGGGGACCTGATGGTGGCCACTGGCTGGATATCAAC
CTTGCTTTTCCAACCACTTGGGTCACGGTCATTGGAATGAATTGCTGTTATTTCCCTGGGGTGC
CAGGACTCCAGTGCTGGGCTGTAACTGGGTGTTGCTGGGGTCTCAGTGCTGCTGAGCTTTAGGG
GACTAGATGCCAGCCATGGTTGCCCTCACCATCCAGAGGGCTGTTTGGTTCTTTGGCACATCAG
GCAAGCTGTGTCTGTATAAAGTGTCACATAAAAACCCTGGGTCTCTGGCTACACTTTCAGTTCC
TGGGGCTGAGAAAACTCCTTGCATCAAGGGGTCAAGAAACAAGGAATTTTAGGGTAACTGGTTC
TAAAGCCCTCTCTTGTGTGTGCACATTGATTTGAGGGTATGTTTTCTTCAGAATGGTGTTAGTG
CAGTTGAGATGCAATTTGAAGTTATTTTCTTAATGTGACATAGCCATGGGCATGGCCATGTGCG
TACAATATGGTGGCTGACTTGATGTATACTCCTAACTTAATAAATAATGTGCAACCATC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001128345	(Get FASTA)	NCBI Sequence Viewer
	XP_006238843	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI61954	(Get FASTA)	NCBI Sequence Viewer
	EDL80336	(Get FASTA)	NCBI Sequence Viewer
	EDL80337	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001128345 ⟸ NM_001134873

- UniProtKB:

B1WC02 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKYILVTGGVISGIGKGVIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDG
GEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQ
ALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKKENFCNIHVSLVPQPSSTGEQ
KTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLL
LEEQGVVDYFLRRLDLPVERQSRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKA
LEHSALAINHKLEIKYIDSTDLEPSTLQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQA
IAWARKQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPKTSHPVVIDMPEHNPGQMGGTM
RLGKRRTLFQTKNSVMRKLYGDTDYLEERHRHRFEVNPVLKKCLEEQGLKFVGQDVEGERMEIV
ELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLPHYLQKGCRLSPRDTYSDRSGSSSP
DSEITELKFPSISQD

hide sequence

RefSeq Acc Id:	XP_006238843 ⟸ XM_006238781
- Peptide Label:	isoform X1
- UniProtKB:	B1WC02 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKYILVTGGVISGIGKGVIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDG GEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQ ALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKKENFCNIHVSLVPQPSSTGEQ KTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLL LEEQGVVDYFLRRLDLPVERQSRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKA LEHSALAINHKLEIKYIDSTDLEPSTLQEEPVRYHEAWQKLCSAHGVLVPGGFGVRGTEGKIQA IAWARKQKKPFLGVCLGMQLAVVEFSRNVLGWQDANSTEFDPKTSHPVVIDMPEHNPGQMGGTM RLGKRRTLFQTKNSVMRKLYGDTDYLEERHRHRFEVNPVLKKCLEEQGLKFVGQDVEGERMEIV ELEDHPFFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLPHYLQKGCRLSPRDTYSDRSGSSSP DSEITELKFPSISQD hide sequence

RefSeq Acc Id:

ENSRNOP00000013899 ⟸ ENSRNOT00000013899

RefSeq Acc Id:

ENSRNOP00000083296 ⟸ ENSRNOT00000098430

Protein Domains

CTP_synth_N GATase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B1WC02-F1-model_v2	AlphaFold	B1WC02	1-591	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693990

Promoter ID:

EPDNEW_R4514

Type:

initiation region

Name:

Ctps1_1

Description:

CTP synthase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	139,505,023 - 139,505,083	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311060	AgrOrtholog
BioCyc Gene	G2FUF-40069	BioCyc
BioCyc Pathway	CITRULBIO-PWY [L-citrulline biosynthesis]	BioCyc
	GLUTAMINDEG-PWY [L-glutamine degradation I]	BioCyc
	PWY-5921 [glutaminyl-tRNAgln biosynthesis via transamidation]	BioCyc
	PWY-7176 [UTP and CTP de novo biosynthesis]	BioCyc
	PWY-7185 [UTP and CTP dephosphorylation I]	BioCyc
Ensembl Genes	ENSRNOG00000009963	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000013899	ENTREZGENE
	ENSRNOP00000013899.5	UniProtKB/TrEMBL
	ENSRNOP00000083296.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000013899	ENTREZGENE
	ENSRNOT00000013899.6	UniProtKB/TrEMBL
	ENSRNOT00000098430.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
	3.40.50.880	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9027103	IMAGE-MGC_LOAD
InterPro	Class_I_gatase-like	UniProtKB/TrEMBL
	CTP_synthase	UniProtKB/TrEMBL
	CTP_synthase_N	UniProtKB/TrEMBL
	GATase1_CTP_Synthase	UniProtKB/TrEMBL
	GATASE_1	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
KEGG Report	rno:313560	UniProtKB/TrEMBL
MGC_CLONE	MGC:187755	IMAGE-MGC_LOAD
NCBI Gene	313560	ENTREZGENE
PANTHER	PyrG_synth	UniProtKB/TrEMBL
Pfam	CTP_synth_N	UniProtKB/TrEMBL
	GATase	UniProtKB/TrEMBL
PhenoGen	Ctps1	PhenoGen
Superfamily-SCOP	SSF52317	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
TIGRFAMs	PyrG	UniProtKB/TrEMBL
UniProt	A0A8I5ZZ52_RAT	UniProtKB/TrEMBL
	B1WC02	ENTREZGENE, UniProtKB/TrEMBL
	F7F0L0_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-07-16	Ctps1	CTP synthase 1	Ctps	CTP synthase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-26	Ctps	CTP synthase	Ctps	cytidine 5'-triphosphate synthase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Ctps	cytidine 5'-triphosphate synthase	Ctps_predicted	cytidine 5'-triphosphate synthase (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Ctps_predicted	cytidine 5'-triphosphate synthase (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)