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Gene: Kdm1a (lysine demethylase 1A) Rattus norvegicus
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Symbol: Kdm1a
Name: lysine demethylase 1A
Description: Exhibits chromatin binding activity and transcription factor binding activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; cellular response to cAMP; and nervous system development. Localizes to the nuclear chromatin. Biomarker of breast cancer; diabetic retinopathy; schizophrenia; and transient cerebral ischemia. Orthologous to human KDM1A (lysine demethylase 1A); PARTICIPATES IN histone modification pathway; Notch signaling pathway; INTERACTS WITH aldehydo-D-glucose; bisphenol A; D-glucose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: amine oxidase (flavin containing) domain 2; Aof2; Kdm1; LOC500569; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; lysine-specific histone demethylase 1A; neuroprotective protein 3; RGD1562975; similar to AOF2 protein
Orthologs:
Homo sapiens (human) : KDM1A (lysine demethylase 1A)  HGNC  Alliance
Mus musculus (house mouse) : Kdm1a (lysine (K)-specific demethylase 1A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm1a (lysine demethylase 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM1A (lysine demethylase 1A)
Canis lupus familiaris (dog) : KDM1A (lysine demethylase 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm1a (lysine demethylase 1A)
Sus scrofa (pig) : KDM1A (lysine demethylase 1A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05154,909,003 - 154,965,171 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05158,674,383 - 158,730,358 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45155,299,289 - 155,358,404 (-)NCBIRGSC3.4rn4RGSC3.4
Celera5147,184,121 - 147,238,797 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Kdm1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562975
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.