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Gene: Park7 (Parkinsonism associated deglycase) Rattus norvegicus
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Symbol: Park7
Name: Parkinsonism associated deglycase
Description: Predicted to have several functions, including DNA-binding transcription factor binding activity; enzyme binding activity; and transition metal ion binding activity. Involved in several processes, including cellular response to lipopolysaccharide; maternal process involved in female pregnancy; and negative regulation of NMDA glutamate receptor activity. Localizes to several cellular components, including endoplasmic reticulum; membrane raft; and sperm head. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease; Parkinson's disease 7; cerebral infarction; and middle cerebral artery infarction. Orthologous to human PARK7 (Parkinsonism associated deglycase); PARTICIPATES IN Parkinson's disease pathway; INTERACTS WITH 1-bromopropane; 15-deoxy-Delta(12,14)-prostaglandin J2; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CAP1; contraception-associated protein 1; DJ-1; Dj1; fertility protein SP22; maillard deglycase; Parkinson disease (autosomal recessive, early onset) 7; parkinson disease protein 7 homolog; parkinson protein 7; protein/nucleic acid deglycase DJ-1; SP22
Orthologs:
Homo sapiens (human) : PARK7 (Parkinsonism associated deglycase)  HGNC  Alliance
Mus musculus (house mouse) : Park7 (Parkinson disease (autosomal recessive, early onset) 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Park7 (Parkinsonism associated deglycase)
Pan paniscus (bonobo/pygmy chimpanzee) : PARK7 (Parkinsonism associated deglycase)
Canis lupus familiaris (dog) : PARK7 (Parkinsonism associated deglycase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Park7 (Parkinsonism associated deglycase)
Sus scrofa (pig) : PARK7 (Parkinsonism associated deglycase)
Chlorocebus sabaeus (African green monkey) : PARK7 (Parkinsonism associated deglycase)
Heterocephalus glaber (naked mole-rat) : Park7 (Parkinsonism associated deglycase)
more info ...
Related Pseudogenes: LOC365828   LOC689000   RGD1560648  
Allele / Splice: Park7em1Sage  
Genetic Models: LE-Park7em1Sage-/- LE-Park7em1Sage
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05167,982,438 - 168,004,724 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5167,982,439 - 168,004,724 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05171,559,202 - 171,582,476 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45168,050,149 - 168,061,616 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15168,060,336 - 168,071,804 (-)NCBI
Celera5159,607,648 - 159,630,713 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Park7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621808
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.