Gene: Ago1 (argonaute RISC catalytic component 1) Rattus norvegicus
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Symbol: Ago1
Name: argonaute RISC catalytic component 1
Description: ENCODES a protein that exhibits core promoter binding (ortholog); double-stranded RNA binding (ortholog); miRNA binding (ortholog); INVOLVED IN miRNA loading onto RISC involved in gene silencing by miRNA (ortholog); miRNA mediated inhibition of translation (ortholog); miRNA metabolic process (ortholog); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); genetic disease (ortholog); malignant mesothelioma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); micro-ribonucleoprotein complex (ortholog); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: argonaute 1, RISC catalytic component; Eif2c1; eukaryotic translation initiation factor 2C, 1; LOC313594; protein argonaute-1
Orthologs:
Homo sapiens (human) : AGO1 (argonaute RISC component 1)  HGNC  Alliance
Mus musculus (house mouse) : Ago1 (argonaute RISC catalytic subunit 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago1 (argonaute RISC catalytic component 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AGO1 (argonaute RISC catalytic component 1)
Canis lupus familiaris (dog) : AGO1 (argonaute RISC catalytic component 1)
Sus scrofa (pig) : AGO1 (argonaute RISC catalytic component 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05144,444,390 - 144,479,430 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05148,214,328 - 148,246,407 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45145,797,436 - 145,829,516 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15145,806,727 - 145,840,972 (-)NCBI
Celera5137,218,551 - 137,248,255 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ago1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304619
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE