(-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 epigallocatechin gallate inhibits the reaction [Oxygen deficiency results in decreased expression of MFN2 mRNA] more ... CTD PMID:28478070 (-)-epigallocatechin 3-gallate increases response to substance EXP 6480464 MFN2 protein results in increased susceptibility to epigallocatechin gallate CTD PMID:28478070 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO RGD:732569 6480464 o, p'-DDT results in increased expression of MFN2 mRNA CTD PMID:19371625 1,2-dichloroethane increases expression ISO RGD:732570 6480464 ethylene dichloride results in increased expression of MFN2 mRNA CTD PMID:28960355 1,2-dimethylhydrazine multiple interactions ISO RGD:732570 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MFN2 mRNA CTD PMID:22206623 1,2-dimethylhydrazine decreases expression ISO RGD:732570 6480464 1, 2-Dimethylhydrazine results in decreased expression of MFN2 mRNA CTD PMID:22206623 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:732569 6480464 2 more ... CTD PMID:30714368 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732570 6480464 Tetrachlorodibenzodioxin affects the expression of MFN2 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of MFN2 mRNA CTD PMID:33387578 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of MFN2 mRNA CTD PMID:21346803 2-tert-butylhydroquinone multiple interactions EXP 6480464 2-tert-butylhydroquinone inhibits the reaction [thallium nitrate results in decreased expression of MFN2 protein] CTD PMID:31726083 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of MFN2 protein CTD PMID:31726083 3,4-methylenedioxymethamphetamine increases expression ISO RGD:732570 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of MFN2 mRNA CTD PMID:20188158 3-chloropropane-1,2-diol decreases expression ISO RGD:732569 6480464 alpha-Chlorohydrin results in decreased expression of MFN2 protein CTD PMID:33651226 , PMID:35149085 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of MFN2 protein CTD PMID:34915118 3-chloropropane-1,2-diol multiple interactions EXP 6480464 Diosgenin inhibits the reaction [alpha-Chlorohydrin results in decreased expression of MFN2 protein] CTD PMID:35149085 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of MFN2 protein CTD PMID:33651226 , PMID:35149085 3-chloropropane-1,2-diol multiple interactions ISO RGD:732569 6480464 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in decreased expression of MFN2 protein], Diosgenin inhibits the reaction [alpha-Chlorohydrin results in decreased expression of MFN2 protein] CTD PMID:33651226 , PMID:35149085 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of MFN2 mRNA CTD PMID:36041667 4,4'-sulfonyldiphenol increases expression ISO RGD:732569 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of MFN2 protein CTD PMID:34186270 4,4'-sulfonyldiphenol affects methylation ISO RGD:732570 6480464 bis(4-hydroxyphenyl)sulfone affects the methylation of MFN2 gene CTD PMID:31683443 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of MFN2 mRNA CTD PMID:21346803 4-DAMP(1+) decreases expression EXP 6480464 4-diphenylacetoxy-1, 1-dimethylpiperidinium results in decreased expression of MFN2 protein CTD PMID:27491814 4-phenylbutyric acid increases expression EXP 6480464 4-phenylbutyric acid results in increased expression of MFN2 protein CTD PMID:33651226 4-phenylbutyric acid multiple interactions ISO RGD:732569 6480464 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in decreased expression of MFN2 protein] CTD PMID:33651226 5-fluorouracil affects expression ISO RGD:732569 6480464 Fluorouracil affects the expression of MFN2 mRNA CTD PMID:16584549 5-fluorouracil increases expression ISO RGD:732569 6480464 Fluorouracil results in increased expression of MFN2 protein CTD PMID:30518710 5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid increases expression ISO RGD:732569 6480464 acipimox results in increased expression of MFN2 mRNA CTD PMID:25352640 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO RGD:732570 6480464 6-chloro-2 more ... CTD PMID:34738708 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of MFN2 mRNA CTD PMID:31881176 acetylleucyl-leucyl-norleucinal multiple interactions ISO RGD:732570 6480464 acetylleucyl-leucyl-norleucinal inhibits the reaction [Acetaminophen results in decreased expression of and results in increased cleavage of MFN2 protein] CTD PMID:35713544 aflatoxin B1 increases methylation ISO RGD:732569 6480464 Aflatoxin B1 results in increased methylation of MFN2 intron CTD PMID:30157460 AICA ribonucleotide multiple interactions EXP 6480464 AICA ribonucleotide inhibits the reaction [Acetaminophen results in decreased expression of MFN2 protein], AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of MFN2 protein] CTD PMID:27792760 aldehydo-D-glucose multiple interactions EXP 6480464 cinnamic acid inhibits the reaction [Glucose results in decreased expression of MFN2 protein] more ... CTD PMID:27684054 , PMID:30144576 aldehydo-D-glucose multiple interactions ISO RGD:732569 6480464 [Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA, Melatonin affects the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA] CTD PMID:33962019 aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of MFN2 protein CTD PMID:30144576 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of MFN2 protein CTD PMID:27684054 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of MFN2 mRNA, Tretinoin results in increased expression of MFN2 protein CTD PMID:17151820 all-trans-retinoic acid increases expression ISO RGD:732569 6480464 Tretinoin results in increased expression of MFN2 mRNA CTD PMID:33167477 alloxan multiple interactions EXP 6480464 imisopasem manganese inhibits the reaction [Alloxan results in decreased expression of MFN2 protein] CTD PMID:28483572 alloxan decreases expression EXP 6480464 Alloxan results in decreased expression of MFN2 protein CTD PMID:28483572 alpha-D-galactose increases expression EXP 6480464 Galactose results in increased expression of MFN2 protein CTD PMID:28302704 alpha-D-galactose multiple interactions ISO RGD:732569 6480464 MIR34A mRNA promotes the reaction [Galactose results in increased expression of MFN2 protein] CTD PMID:28302704 alpha-D-galactose increases expression ISO RGD:732569 6480464 Galactose results in increased expression of MFN2 protein CTD PMID:28302704 AM-251 decreases expression ISO RGD:732569 6480464 AM 251 results in decreased expression of MFN2 mRNA CTD PMID:16500647 amiodarone increases expression ISO RGD:732570 6480464 Amiodarone results in increased expression of MFN2 mRNA CTD PMID:24489787 amlodipine increases expression EXP 6480464 Amlodipine results in increased expression of MFN2 mRNA, Amlodipine results in increased expression of MFN2 protein CTD PMID:25464244 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of MFN2 mRNA CTD PMID:16483693 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of MFN2 mRNA CTD PMID:30779732 aristolochic acid A increases expression ISO RGD:732569 6480464 aristolochic acid I results in increased expression of MFN2 mRNA CTD PMID:33212167 arsenite(3-) increases expression ISO RGD:732570 6480464 arsenite results in increased expression of MFN2 mRNA CTD PMID:24960579 arsenous acid increases expression ISO RGD:732570 6480464 Arsenic Trioxide results in increased expression of MFN2 protein CTD PMID:29867492 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of MFN2 protein CTD PMID:29867492 arsenous acid multiple interactions ISO RGD:732570 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of MFN2 protein] CTD PMID:29867492 arsenous acid multiple interactions EXP 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of MFN2 protein] CTD PMID:29867492 atorvastatin calcium multiple interactions EXP 6480464 Atorvastatin inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of MFN2 protein] CTD PMID:24721408 ATP multiple interactions EXP 6480464 MFN2 protein inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased chemical synthesis of Adenosine Triphosphate] CTD PMID:24898700 ATP multiple interactions ISO RGD:732569 6480464 MFN2 protein inhibits the reaction [TNF protein results in decreased chemical synthesis of Adenosine Triphosphate] CTD PMID:24898700 ATP increases chemical synthesis ISO RGD:732570 6480464 MFN2 protein results in increased chemical synthesis of Adenosine Triphosphate CTD PMID:25416777 ATP decreases response to substance ISO RGD:732570 6480464 MFN2 results in decreased susceptibility to Adenosine Triphosphate deficiency CTD PMID:22292091 azide multiple interactions ISO RGD:732569 6480464 MFN2 protein inhibits the reaction [Azides results in increased activity of BAX protein] CTD PMID:21160028 azide decreases response to substance ISO RGD:732569 6480464 MFN2 protein results in decreased susceptibility to Azides CTD PMID:21160028 benzo[a]pyrene decreases methylation ISO RGD:732569 6480464 Benzo(a)pyrene results in decreased methylation of MFN2 5' UTR CTD PMID:27901495 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of MFN2 protein CTD PMID:35940284 benzo[a]pyrene multiple interactions EXP 6480464 ramelteon inhibits the reaction [Benzo(a)pyrene results in increased expression of MFN2 protein] CTD PMID:35940284 benzo[a]pyrene affects methylation ISO RGD:732569 6480464 Benzo(a)pyrene affects the methylation of MFN2 intron, Benzo(a)pyrene affects the methylation of MFN2 promoter CTD PMID:27901495 , PMID:30157460 benzo[a]pyrene diol epoxide I increases expression ISO RGD:732569 6480464 7 more ... CTD PMID:35940284 benzo[e]pyrene decreases methylation ISO RGD:732569 6480464 benzo(e)pyrene results in decreased methylation of MFN2 intron CTD PMID:30157460 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:732570 6480464 Diethylhexyl Phthalate results in decreased expression of MFN2 protein CTD PMID:31408635 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:732570 6480464 Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of MFN2 protein], PRDX5 protein inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of MFN2 protein] CTD PMID:31408635 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of MFN2 mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:732569 6480464 bisphenol A results in increased expression of MFN2 protein CTD PMID:34186270 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of MFN2 mRNA CTD PMID:36041667 bisphenol A decreases expression ISO RGD:732570 6480464 bisphenol A results in decreased expression of MFN2 mRNA CTD PMID:34186417 bisphenol A increases expression ISO RGD:732570 6480464 bisphenol A results in increased expression of MFN2 mRNA CTD PMID:33221593 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of MFN2 gene CTD PMID:28505145 bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of MFN2 mRNA CTD PMID:36041667 butanal decreases expression ISO RGD:732569 6480464 butyraldehyde results in decreased expression of MFN2 mRNA CTD PMID:26079696 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of MFN2 mRNA CTD PMID:25388156 cadmium atom multiple interactions ISO RGD:732569 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MFN2 mRNA CTD PMID:35301059 cadmium atom multiple interactions ISO RGD:732570 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MFN2 protein CTD PMID:34952138 cadmium dichloride multiple interactions ISO RGD:732570 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of MFN2 protein CTD PMID:34952138 cadmium dichloride multiple interactions ISO RGD:732569 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MFN2 mRNA CTD PMID:35301059 Calpeptin multiple interactions ISO RGD:732570 6480464 calpeptin inhibits the reaction [Acetaminophen results in decreased expression of and results in increased cleavage of MFN2 protein], calpeptin inhibits the reaction [CAPN1 protein results in increased degradation of MFN2 protein] CTD PMID:25416777 , PMID:35713544 Calpeptin multiple interactions EXP 6480464 calpeptin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of MFN2 protein] CTD PMID:25416777 Calpeptin multiple interactions ISO RGD:732569 6480464 calpeptin inhibits the reaction [CAPN1 protein results in increased degradation of MFN2 protein] CTD PMID:25416777 Candesartan cilexetil increases expression EXP 6480464 candesartan cilexetil results in increased expression of MFN2 mRNA, candesartan cilexetil results in increased expression of MFN2 protein CTD PMID:25464244 , PMID:27085127 carnosic acid multiple interactions ISO RGD:732569 6480464 salvin inhibits the reaction [Oxidopamine results in decreased expression of MFN2 protein] CTD PMID:31705926 Carnosol multiple interactions ISO RGD:732570 6480464 carnosol inhibits the reaction [Dietary Fats results in decreased expression of MFN2 protein] more ... CTD PMID:34678374 CCCP multiple interactions EXP 6480464 BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein], Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein CTD PMID:24879156 CCCP multiple interactions ISO RGD:732569 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and affects the localization of MFN2 protein CTD PMID:28940366 cisplatin multiple interactions ISO RGD:732570 6480464 MFN2 protein inhibits the reaction [Cisplatin results in increased activity of BAX protein] CTD PMID:21160028 cisplatin decreases response to substance ISO RGD:732570 6480464 MFN2 protein results in decreased susceptibility to Cisplatin CTD PMID:21160028 cobalt dichloride affects expression ISO RGD:732569 6480464 cobaltous chloride affects the expression of MFN2 mRNA alternative form CTD PMID:19320972 corticosterone decreases expression EXP 6480464 Corticosterone results in decreased expression of MFN2 mRNA CTD PMID:22244747 crocidolite asbestos affects expression ISO RGD:732569 6480464 Asbestos, Crocidolite affects the expression of MFN2 mRNA CTD PMID:17331233 cyclosporin A increases methylation ISO RGD:732569 6480464 Cyclosporine results in increased methylation of MFN2 promoter CTD PMID:27989131 D-glucose multiple interactions EXP 6480464 cinnamic acid inhibits the reaction [Glucose results in decreased expression of MFN2 protein] more ... CTD PMID:27684054 , PMID:30144576 D-glucose multiple interactions ISO RGD:732569 6480464 [Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA, Melatonin affects the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA] CTD PMID:33962019 D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of MFN2 protein CTD PMID:30144576 D-glucose increases expression EXP 6480464 Glucose results in increased expression of MFN2 protein CTD PMID:27684054 desferrioxamine B multiple interactions ISO RGD:732569 6480464 [Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA, Melatonin affects the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA] CTD PMID:33962019 diarsenic trioxide multiple interactions ISO RGD:732570 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of MFN2 protein] CTD PMID:29867492 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of MFN2 protein CTD PMID:29867492 diarsenic trioxide increases expression ISO RGD:732570 6480464 Arsenic Trioxide results in increased expression of MFN2 protein CTD PMID:29867492 diarsenic trioxide multiple interactions EXP 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of MFN2 protein] CTD PMID:29867492 diclofenac decreases expression EXP 6480464 Diclofenac results in decreased expression of MFN2 protein CTD PMID:27792760 diclofenac multiple interactions EXP 6480464 AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of MFN2 protein] CTD PMID:27792760 diosgenin multiple interactions ISO RGD:732569 6480464 Diosgenin inhibits the reaction [alpha-Chlorohydrin results in decreased expression of MFN2 protein] CTD PMID:35149085 diosgenin multiple interactions EXP 6480464 Diosgenin inhibits the reaction [alpha-Chlorohydrin results in decreased expression of MFN2 protein] CTD PMID:35149085 dioxygen decreases expression EXP 6480464 Oxygen deficiency results in decreased expression of MFN2 mRNA, Oxygen deficiency results in decreased expression of MFN2 protein CTD PMID:26593335 more ... dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of MFN2 mRNA more ... CTD PMID:24721408 more ... dioxygen multiple interactions ISO RGD:732570 6480464 [Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of MFN2 protein, genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of MFN2 protein] CTD PMID:28477916 dizocilpine maleate multiple interactions EXP 6480464 Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of MFN2 protein] CTD PMID:25416777 dorsomorphin decreases expression EXP 6480464 dorsomorphin results in decreased expression of MFN2 protein CTD PMID:27491814 dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [sappanone A inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of MFN2 protein]] CTD PMID:34358556 dorsomorphin multiple interactions ISO RGD:732570 6480464 dorsomorphin inhibits the reaction [Resveratrol results in increased expression of MFN2 mRNA] CTD PMID:17438283 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of MFN2 mRNA, Doxorubicin results in decreased expression of MFN2 protein CTD PMID:19915844 more ... doxorubicin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Doxorubicin results in decreased expression of MFN2 protein] CTD PMID:29966675 doxorubicin decreases expression ISO RGD:732569 6480464 Doxorubicin results in decreased expression of MFN2 mRNA, Doxorubicin results in decreased expression of MFN2 protein CTD PMID:29729358 , PMID:29803840 doxorubicin increases expression ISO RGD:732570 6480464 Doxorubicin results in increased expression of MFN2 mRNA CTD PMID:28710503 doxorubicin multiple interactions ISO RGD:732570 6480464 [resveratrol co-treated with Doxorubicin] results in increased expression of MFN2 protein more ... CTD PMID:23695218 , PMID:28710503 efavirenz increases expression ISO RGD:732569 6480464 efavirenz results in increased expression of MFN2 mRNA CTD PMID:28940366 entinostat decreases expression ISO RGD:732569 6480464 entinostat results in decreased expression of MFN2 mRNA CTD PMID:27188386 epoxiconazole decreases expression ISO RGD:732570 6480464 epoxiconazole results in decreased expression of MFN2 mRNA CTD PMID:35436446 ethanol increases degradation ISO RGD:732570 6480464 Ethanol results in increased degradation of MFN2 protein CTD PMID:25460735 ethanol affects splicing ISO RGD:732570 6480464 Ethanol affects the splicing of MFN2 mRNA CTD PMID:30319688 ethanol multiple interactions ISO RGD:732570 6480464 NR1H4 gene mutant form inhibits the reaction [Ethanol results in increased degradation of MFN2 protein] CTD PMID:25460735 excitatory amino acid agonist decreases response to substance ISO RGD:732569 6480464 MFN2 protein results in decreased susceptibility to Excitatory Amino Acid Agonists CTD PMID:25416777 excitatory amino acid agonist multiple interactions ISO RGD:732569 6480464 MFN2 protein inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of CASP3 protein modified form] CTD PMID:25416777 excitatory amino acid agonist multiple interactions EXP 6480464 1 more ... CTD PMID:25416777 excitatory amino acid agonist decreases expression EXP 6480464 Excitatory Amino Acid Agonists results in decreased expression of MFN2 protein CTD PMID:25416777 excitatory amino acid agonist decreases response to substance ISO RGD:732570 6480464 MFN2 protein results in decreased susceptibility to Excitatory Amino Acid Agonists CTD PMID:25416777 excitatory amino acid agonist decreases response to substance EXP 6480464 MFN2 protein results in decreased susceptibility to Excitatory Amino Acid Agonists CTD PMID:25416777 excitatory amino acid agonist decreases expression ISO RGD:732570 6480464 Excitatory Amino Acid Agonists results in decreased expression of MFN2 protein CTD PMID:25416777 fenbendazole increases expression ISO RGD:732569 6480464 Fenbendazole results in increased expression of MFN2 mRNA CTD PMID:35569513 fenofibrate multiple interactions ISO RGD:732569 6480464 Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein] CTD PMID:32730863 ferulic acid multiple interactions EXP 6480464 ferulic acid inhibits the reaction [Streptozocin results in decreased expression of MFN2 protein] CTD PMID:31029786 finasteride increases expression EXP 6480464 Finasteride results in increased expression of MFN2 mRNA CTD PMID:24136188 flutamide increases expression EXP 6480464 Flutamide results in increased expression of MFN2 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:732570 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MFN2 mRNA CTD PMID:22206623 fructose multiple interactions ISO RGD:732569 6480464 [Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein, Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein] CTD PMID:32730863 galactose increases expression EXP 6480464 Galactose results in increased expression of MFN2 protein CTD PMID:28302704 galactose multiple interactions ISO RGD:732569 6480464 MIR34A mRNA promotes the reaction [Galactose results in increased expression of MFN2 protein] CTD PMID:28302704 galactose increases expression ISO RGD:732569 6480464 Galactose results in increased expression of MFN2 protein CTD PMID:28302704 Genipin multiple interactions ISO RGD:732570 6480464 genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of MFN2 protein] CTD PMID:28477916 genistein increases expression ISO RGD:732569 6480464 Genistein results in increased expression of MFN2 mRNA CTD PMID:19371625 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of MFN2 mRNA CTD PMID:22061828 , PMID:33387578 ginsenoside Rg1 multiple interactions EXP 6480464 ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in decreased expression of MFN2 mRNA], ginsenoside Rg1 inhibits the reaction [Oxygen deficiency results in decreased expression of MFN2 protein] CTD PMID:26593335 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of MFN2 mRNA CTD PMID:24136188 glucose increases expression EXP 6480464 Glucose results in increased expression of MFN2 protein CTD PMID:27684054 glucose multiple interactions ISO RGD:732569 6480464 [Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA, Melatonin affects the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA] CTD PMID:33962019 glucose decreases expression EXP 6480464 Glucose results in decreased expression of MFN2 protein CTD PMID:30144576 glucose multiple interactions EXP 6480464 cinnamic acid inhibits the reaction [Glucose results in decreased expression of MFN2 protein] more ... CTD PMID:27684054 , PMID:30144576 GW 4064 multiple interactions ISO RGD:732570 6480464 GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of MFN2 mRNA] CTD PMID:28223344 hexadecanoic acid multiple interactions ISO RGD:732569 6480464 [Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein, Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein] CTD PMID:32730863 hexadecanoic acid multiple interactions ISO RGD:732570 6480464 carnosol inhibits the reaction [Palmitic Acid results in decreased expression of MFN2 protein] more ... CTD PMID:34678374 hexadecanoic acid decreases expression ISO RGD:732570 6480464 Palmitic Acid results in decreased expression of MFN2 protein CTD PMID:34678374 homocysteine decreases expression ISO RGD:732569 6480464 Homocysteine results in decreased expression of MFN2 protein CTD PMID:33751715 Honokiol multiple interactions EXP 6480464 honokiol inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of MFN2 protein], SIRT3 protein affects the reaction [honokiol inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of MFN2 protein]] CTD PMID:34752757 hydrogen peroxide multiple interactions EXP 6480464 MFN2 protein mutant form inhibits the reaction [ALB protein modified form results in increased abundance of Hydrogen Peroxide] CTD PMID:27997345 isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of MFN2 protein CTD PMID:26692091 , PMID:27491814 ivermectin decreases expression ISO RGD:732569 6480464 Ivermectin results in decreased expression of MFN2 protein CTD PMID:32959892 lamivudine multiple interactions ISO RGD:732570 6480464 [Zidovudine co-treated with Lamivudine] results in increased expression of MFN2 mRNA CTD PMID:18313992 lenvatinib affects expression EXP 6480464 lenvatinib affects the expression of MFN2 mRNA CTD PMID:34019861 linuron decreases expression EXP 6480464 Linuron results in decreased expression of MFN2 mRNA CTD PMID:28705778 lovastatin multiple interactions ISO RGD:732570 6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased expression of MFN2 mRNA] CTD PMID:28710503 mabuterol multiple interactions EXP 6480464 [mabuterol co-treated with 3-(2 more ... CTD PMID:31009640 manganese(II) chloride decreases expression ISO RGD:732570 6480464 manganese chloride results in decreased expression of MFN2 mRNA, manganese chloride results in decreased expression of MFN2 protein CTD PMID:28539244 , PMID:34738708 manganese(II) chloride multiple interactions ISO RGD:732570 6480464 6-chloro-2 more ... CTD PMID:34738708 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of MFN2 protein], Melatonin inhibits the reaction [Doxorubicin results in decreased expression of MFN2 protein] CTD PMID:26882442 , PMID:29966675 melatonin increases expression ISO RGD:732569 6480464 Melatonin results in increased expression of MFN2 mRNA CTD PMID:33962019 melatonin multiple interactions ISO RGD:732569 6480464 Melatonin affects the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of MFN2 mRNA] CTD PMID:33962019 metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [Glucose results in decreased expression of MFN2 protein] CTD PMID:30144576 methapyrilene decreases methylation ISO RGD:732569 6480464 Methapyrilene results in decreased methylation of MFN2 intron CTD PMID:30157460 methidathion decreases expression ISO RGD:732570 6480464 methidathion results in decreased expression of MFN2 mRNA CTD PMID:34813904 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [ALB protein modified form results in decreased expression of MFN2 protein] CTD PMID:27997345 N-acetyl-L-cysteine multiple interactions ISO RGD:732570 6480464 Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of MFN2 protein] CTD PMID:31408635 N-acetylsphingosine decreases response to substance EXP 6480464 MFN2 protein results in decreased susceptibility to N-acetylsphingosine CTD PMID:18006463 N-hexadecanoylsphingosine increases expression ISO RGD:732570 6480464 N-palmitoylsphingosine results in increased expression of MFN2 mRNA CTD PMID:28223344 N-hexadecanoylsphingosine multiple interactions ISO RGD:732570 6480464 [N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of MFN2 mRNA, ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of MFN2 mRNA] CTD PMID:28223344 nitrogen dioxide multiple interactions ISO RGD:732570 6480464 [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN2 protein CTD PMID:27521637 NSC 23766 multiple interactions ISO RGD:732570 6480464 NSC 23766 inhibits the reaction [Doxorubicin results in increased expression of MFN2 mRNA] CTD PMID:28710503 okadaic acid increases expression EXP 6480464 Okadaic Acid results in increased expression of MFN2 protein CTD PMID:26732598 oxidopamine multiple interactions ISO RGD:732569 6480464 salvin inhibits the reaction [Oxidopamine results in decreased expression of MFN2 protein] CTD PMID:31705926 oxidopamine decreases expression ISO RGD:732569 6480464 Oxidopamine results in decreased expression of MFN2 protein CTD PMID:31705926 paclitaxel decreases expression EXP 6480464 Paclitaxel results in decreased expression of MFN2 mRNA CTD PMID:28587902 paracetamol affects expression ISO RGD:732570 6480464 Acetaminophen affects the expression of MFN2 mRNA CTD PMID:17562736 paracetamol multiple interactions ISO RGD:732570 6480464 Acetaminophen results in decreased expression of and results in increased cleavage of MFN2 protein more ... CTD PMID:35713544 paracetamol multiple interactions EXP 6480464 AICA ribonucleotide inhibits the reaction [Acetaminophen results in decreased expression of MFN2 protein] CTD PMID:27792760 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of MFN2 mRNA, Acetaminophen results in decreased expression of MFN2 protein CTD PMID:27792760 , PMID:33387578 paracetamol decreases expression ISO RGD:732569 6480464 Acetaminophen results in decreased expression of MFN2 mRNA CTD PMID:21420995 paraquat multiple interactions ISO RGD:732569 6480464 MFN2 inhibits the reaction [Paraquat results in increased phosphorylation of MAPK8 protein], MFN2 inhibits the reaction [Paraquat results in increased phosphorylation of MAPK9 protein] CTD PMID:28215578 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:732570 6480464 perfluorooctane sulfonic acid results in decreased expression of MFN2 protein CTD PMID:28288859 perfluorooctanoic acid increases expression ISO RGD:732569 6480464 perfluorooctanoic acid results in increased expression of MFN2 protein CTD PMID:26879310 perindopril increases expression EXP 6480464 Perindopril results in increased expression of MFN2 mRNA, Perindopril results in increased expression of MFN2 protein CTD PMID:25464244 phenethyl caffeate multiple interactions ISO RGD:732570 6480464 [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of MFN2 mRNA, GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of MFN2 mRNA] CTD PMID:28223344 phenylephrine decreases expression EXP 6480464 Phenylephrine results in decreased expression of MFN2 mRNA, Phenylephrine results in decreased expression of MFN2 protein CTD PMID:17499311 , PMID:20886221 phenylephrine multiple interactions EXP 6480464 CAT protein inhibits the reaction [Phenylephrine results in decreased expression of MFN2 protein] more ... CTD PMID:20886221 pirinixic acid increases expression ISO RGD:732570 6480464 pirinixic acid results in increased expression of MFN2 mRNA CTD PMID:18301758 potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of MFN2 protein CTD PMID:32980475 pyrroloquinoline quinone multiple interactions EXP 6480464 PQQ Cofactor inhibits the reaction [Rotenone results in decreased expression of MFN2 mRNA] CTD PMID:30240821 pyrroloquinoline quinone multiple interactions ISO RGD:732569 6480464 PQQ Cofactor inhibits the reaction [Rotenone affects the localization of MFN2 protein], PQQ Cofactor inhibits the reaction [Rotenone results in decreased expression of MFN2 mRNA] CTD PMID:30240821 reactive oxygen species decreases chemical synthesis ISO RGD:732570 6480464 MFN2 protein results in decreased chemical synthesis of Reactive Oxygen Species CTD PMID:25416777 reactive oxygen species multiple interactions ISO RGD:732569 6480464 MFN2 protein inhibits the reaction [TNF protein results in increased chemical synthesis of Reactive Oxygen Species] CTD PMID:24898700 reactive oxygen species multiple interactions EXP 6480464 MFN2 protein inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased chemical synthesis of Reactive Oxygen Species] CTD PMID:24898700 regorafenib increases expression EXP 6480464 regorafenib results in increased expression of MFN2 mRNA CTD PMID:33166663 resveratrol increases expression ISO RGD:732569 6480464 resveratrol results in increased expression of MFN2 mRNA CTD PMID:19371625 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Rotenone results in decreased expression of MFN2 mRNA], resveratrol inhibits the reaction [Rotenone results in decreased expression of MFN2 protein] CTD PMID:26770656 resveratrol increases expression ISO RGD:732570 6480464 resveratrol results in increased expression of MFN2 mRNA CTD PMID:17438283 resveratrol multiple interactions ISO RGD:732570 6480464 6-chloro-2 more ... CTD PMID:17438283 more ... rotenone decreases expression ISO RGD:732570 6480464 Rotenone results in decreased expression of MFN2 mRNA CTD PMID:23186747 rotenone increases expression EXP 6480464 Rotenone results in increased expression of MFN2 protein CTD PMID:35544339 rotenone increases expression ISO RGD:732569 6480464 Rotenone results in increased expression of MFN2 protein CTD PMID:31926197 rotenone affects localization ISO RGD:732569 6480464 Rotenone affects the localization of MFN2 protein CTD PMID:30240821 rotenone multiple interactions ISO RGD:732569 6480464 polydatin inhibits the reaction [Rotenone results in increased expression of MFN2 protein] more ... CTD PMID:28940366 more ... rotenone decreases expression ISO RGD:732569 6480464 Rotenone results in decreased expression of MFN2 mRNA, Rotenone results in decreased expression of MFN2 protein CTD PMID:24792327 , PMID:30240821 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of MFN2 mRNA, Rotenone results in decreased expression of MFN2 protein CTD PMID:26770656 , PMID:30240821 rotenone multiple interactions EXP 6480464 PQQ Cofactor inhibits the reaction [Rotenone results in decreased expression of MFN2 mRNA] more ... CTD PMID:26770656 , PMID:30240821 ruthenium red multiple interactions EXP 6480464 Ruthenium Red inhibits the reaction [Phenylephrine results in decreased expression of MFN2 protein] CTD PMID:20886221 Salvianolic acid A multiple interactions ISO RGD:732570 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of MFN2 protein] CTD PMID:29867492 Salvianolic acid A multiple interactions EXP 6480464 salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of MFN2 protein] CTD PMID:29867492 sevoflurane multiple interactions EXP 6480464 sevoflurane inhibits the reaction [Oxygen deficiency inhibits the reaction [Glucose results in increased expression of MFN2 protein]], sevoflurane inhibits the reaction [Oxygen deficiency results in decreased expression of MFN2 protein] CTD PMID:27684054 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide results in decreased expression of MFN2 mRNA CTD PMID:31034866 sodium arsenite multiple interactions ISO RGD:732569 6480464 MFN2 protein affects the reaction [sodium arsenite results in decreased expression of GPX4 protein] more ... CTD PMID:32593899 sodium arsenite increases expression ISO RGD:732569 6480464 sodium arsenite results in increased expression of MFN2 mRNA CTD PMID:34032870 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of MFN2 protein CTD PMID:31029786 streptozocin multiple interactions ISO RGD:732570 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA, NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA] CTD PMID:33812996 streptozocin multiple interactions EXP 6480464 ferulic acid inhibits the reaction [Streptozocin results in decreased expression of MFN2 protein] more ... CTD PMID:27997345 , PMID:31029786 sulfur dioxide multiple interactions ISO RGD:732570 6480464 [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in decreased expression of MFN2 protein CTD PMID:27521637 tamoxifen decreases expression ISO RGD:732570 6480464 Tamoxifen results in decreased expression of MFN2 mRNA CTD PMID:17555576 tauroursodeoxycholic acid multiple interactions ISO RGD:732570 6480464 ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of MFN2 mRNA] CTD PMID:28223344 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of MFN2 protein CTD PMID:26882442 tetrachloromethane decreases expression ISO RGD:732570 6480464 Carbon Tetrachloride results in decreased expression of MFN2 mRNA CTD PMID:31919559 tetrachloromethane multiple interactions ISO RGD:732570 6480464 [Carbon Tetrachloride co-treated with STF 083010] results in decreased expression of MFN2 mRNA CTD PMID:30538632 tetrachloromethane multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of MFN2 protein] CTD PMID:26882442 thapsigargin increases expression ISO RGD:732569 6480464 Thapsigargin results in increased expression of MFN2 mRNA CTD PMID:28940366 thapsigargin increases expression ISO RGD:732570 6480464 Thapsigargin results in increased expression of MFN2 mRNA CTD PMID:28223344 titanium dioxide increases expression ISO RGD:732570 6480464 titanium dioxide results in increased expression of MFN2 mRNA CTD PMID:29264374 trans-cinnamic acid multiple interactions EXP 6480464 cinnamic acid inhibits the reaction [Glucose results in decreased expression of MFN2 protein] CTD PMID:30144576 trans-piceid multiple interactions ISO RGD:732569 6480464 polydatin inhibits the reaction [Rotenone results in increased expression of MFN2 protein] CTD PMID:31926197 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of MFN2 mRNA CTD PMID:19448997 , PMID:33387578 Triptolide decreases expression ISO RGD:732570 6480464 triptolide results in decreased expression of MFN2 protein CTD PMID:30836114 Triptolide multiple interactions ISO RGD:732570 6480464 mitoquinone inhibits the reaction [triptolide results in decreased expression of MFN2 protein] CTD PMID:30836114 valproic acid decreases expression ISO RGD:732569 6480464 Valproic Acid results in decreased expression of MFN2 mRNA, Valproic Acid results in decreased expression of MFN2 protein CTD PMID:29501571 vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of MFN2 gene CTD PMID:31682807 zearalenone increases expression ISO RGD:732569 6480464 Zearalenone results in increased expression of MFN2 mRNA CTD PMID:19371625 zidovudine multiple interactions ISO RGD:732570 6480464 [Zidovudine co-treated with Lamivudine] results in increased expression of MFN2 mRNA CTD PMID:18313992 zinc atom multiple interactions ISO RGD:732569 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of MFN2 mRNA CTD PMID:18593933 zinc(0) multiple interactions ISO RGD:732569 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of MFN2 mRNA CTD PMID:18593933