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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628843
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mfn2
Name: mitofusin 2
Acc ID: CHEBI:18721
Term: 3-chloropropane-1,2-diol
Definition: A chloropropane-1,2-diol that is propane-1,2-diol substituted by a chloro group at position 3.
Chemical ID: MESH:D000517
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mfn2decreases expressionEXP 6480464CTDalpha-Chlorohydrin results in decreased expression of MFN2 proteinPMID:33651226 PMID:35149085
Mfn2increases expressionEXP 6480464CTDalpha-Chlorohydrin results in increased expression of MFN2 proteinPMID:34915118
Mfn2multiple interactionsEXP 6480464CTDDiosgenin inhibits the reaction [alpha-Chlorohydrin results in decreased expression of MFN2 protein]PMID:35149085
Mfn2decreases expressionISOMFN2 (Homo sapiens)6480464CTDalpha-Chlorohydrin results in decreased expression of MFN2 proteinPMID:33651226 PMID:35149085
Mfn2multiple interactionsISOMFN2 (Homo sapiens)6480464CTD4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in decreased expression of MFN2 protein]; Diosgenin inhibits the reaction [alpha-Chlorohydrin results in decreased expression of MFN2 protein]PMID:33651226 PMID:35149085
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