Zfp933 (zinc finger protein 933) - Rat Genome Database

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Gene: Zfp933 (zinc finger protein 933) Rattus norvegicus
Analyze
Symbol: Zfp933
Name: zinc finger protein 933
RGD ID: 1586231
Description: Predicted to enable metal ion binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II; INTERACTS WITH 1,2-dichloroethane (ortholog); 2,2',4,4',5,5'-hexachlorobiphenyl (ortholog); 2,2',5,5'-tetrachlorobiphenyl (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AC097784.1; LOC691280; similar to Zinc finger protein 180 (HHZ168); zinc finger protein 431
RGD Orthologs
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85163,548,058 - 163,570,132 (-)NCBIGRCr8
mRatBN7.25158,264,875 - 158,285,036 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5158,266,878 - 158,285,000 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.05164,644,438 - 164,665,455 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,646,666 - 164,648,328 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.05168,304,896 - 168,323,445 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45164,913,570 - 164,931,588 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5156,548,494 - 156,568,782 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Zfp933
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85163,548,058 - 163,570,132 (-)NCBIGRCr8
mRatBN7.25158,264,875 - 158,285,036 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5158,266,878 - 158,285,000 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.05164,644,438 - 164,665,455 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,646,666 - 164,648,328 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.05168,304,896 - 168,323,445 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45164,913,570 - 164,931,588 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5156,548,494 - 156,568,782 (-)NCBICelera
Cytogenetic Map5q36NCBI
Zfp933
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394147,906,184 - 147,933,583 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4147,907,443 - 147,932,823 (-)EnsemblGRCm39 Ensembl
GRCm384147,822,986 - 147,849,126 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4147,822,986 - 147,848,366 (-)EnsemblGRCm38mm10GRCm38
MGSCv374147,197,095 - 147,222,484 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364146,666,786 - 146,692,166 (-)NCBIMGSCv36mm8
Celera4150,078,377 - 150,084,174 (-)NCBICelera
Cytogenetic Map4E1NCBI
cM Map478.56NCBI

Variants

.
Variants in Zfp933
184 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat

Markers in Region
RH142743  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25158,268,656 - 158,268,757 (+)MAPPERmRatBN7.2
Rnor_6.05164,648,220 - 164,648,320NCBIRnor6.0
Rnor_5.05168,306,927 - 168,307,027UniSTSRnor5.0
RGSC_v3.45164,914,925 - 164,915,025UniSTSRGSC3.4
Celera5156,552,276 - 156,552,376UniSTS
RH 3.4 Map51091.61UniSTS
Cytogenetic Map5q36UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000090811   ⟹   ENSRNOP00000073141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5158,266,878 - 158,284,999 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097026   ⟹   ENSRNOP00000086686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5158,266,878 - 158,285,000 (-)Ensembl
RefSeq Acc Id: NM_001409281   ⟹   NP_001396210
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85163,548,058 - 163,568,166 (-)NCBI
mRatBN7.25158,264,875 - 158,284,985 (-)NCBI
RefSeq Acc Id: XM_017593872   ⟹   XP_017449361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85163,551,500 - 163,570,132 (-)NCBI
mRatBN7.25158,268,560 - 158,285,036 (-)NCBI
Rnor_6.05164,648,123 - 164,665,424 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593873   ⟹   XP_017449362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85163,551,500 - 163,570,132 (-)NCBI
mRatBN7.25158,268,560 - 158,285,034 (-)NCBI
Rnor_6.05164,648,123 - 164,665,414 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001396210 (Get FASTA)   NCBI Sequence Viewer  
  XP_017449361 (Get FASTA)   NCBI Sequence Viewer  
  XP_017449362 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL81077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073141.2
  ENSRNOP00000086686
  ENSRNOP00000086686.1
Reference Protein Sequences
RefSeq Acc Id: XP_017449361   ⟸   XM_017593872
- Peptide Label: isoform X1
- UniProtKB: A6IU26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449362   ⟸   XM_017593873
- Peptide Label: isoform X2
- UniProtKB: A6IU26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000086686   ⟸   ENSRNOT00000097026
RefSeq Acc Id: ENSRNOP00000073141   ⟸   ENSRNOT00000090811
RefSeq Acc Id: NP_001396210   ⟸   NM_001409281
- UniProtKB: A0A0G2K4R3 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K4R3-F1-model_v2 AlphaFold A0A0G2K4R3 1-421 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586231 AgrOrtholog
BioCyc Gene G2FUF-39207 BioCyc
Ensembl Genes ENSRNOG00000056374 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000090811.2 UniProtKB/TrEMBL
  ENSRNOT00000097026 ENTREZGENE
  ENSRNOT00000097026.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report rno:691280 UniProtKB/TrEMBL
NCBI Gene 691280 ENTREZGENE
PANTHER FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED UniProtKB/TrEMBL
  RIKEN CDNA 6720489N17 GENE-RELATED UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 628 UniProtKB/TrEMBL
  ZNF44 PROTEIN UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
  zf-H2C2_2 UniProtKB/TrEMBL
PhenoGen Zfp933 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000056374 RatGTEx
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A0G2K4R3 ENTREZGENE, UniProtKB/TrEMBL
  A6IU26 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-09-08 Zfp933  zinc finger protein 933  LOC691280  similar to Zinc finger protein 180 (HHZ168)  Name and Symbol changed 629549 APPROVED
2022-06-02 LOC691280  similar to Zinc finger protein 180 (HHZ168)  AC097784.1    Data merged from RGD:15010192 737654 PROVISIONAL
2019-11-08 AC097784.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2006-11-19 LOC691280  similar to Zinc finger protein 180 (HHZ168)      Symbol and Name status set to provisional 70820 PROVISIONAL