Hes5 (hes family bHLH transcription factor 5)

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Gene: Hes5 (hes family bHLH transcription factor 5) Rattus norvegicus

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Symbol:

Hes5

Name:

hes family bHLH transcription factor 5

RGD ID:

621340

Description:

Exhibits chromatin binding activity and double-stranded DNA binding activity. Involved in several processes, including generation of neurons; negative regulation of pro-B cell differentiation; and neuronal stem cell population maintenance. Predicted to localize to nucleus. Orthologous to human HES5 (hes family bHLH transcription factor 5); PARTICIPATES IN Notch signaling pathway; Notch signaling pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

hairy and enhancer of split 5; hairy and enhancer of split 5 (Drosophila); transcription factor HES-5

Orthologs:

Homo sapiens (human) : HES5 (hes family bHLH transcription factor 5) HGNC Alliance
Mus musculus (house mouse) : Hes5 (hes family bHLH transcription factor 5) MGI Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hes5 (hes family bHLH transcription factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : HES5 (hes family bHLH transcription factor 5)
Canis lupus familiaris (dog) : HES5 (hes family bHLH transcription factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hes5 (hes family bHLH transcription factor 5)
Sus scrofa (pig) : HES5 (hes family bHLH transcription factor 5)
Chlorocebus sabaeus (African green monkey) : HES5 (hes family bHLH transcription factor 5)
Heterocephalus glaber (naked mole-rat) : Hes5 (hes family bHLH transcription factor 5)

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	5	172,364,421 - 172,365,188 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	172,364,421 - 172,365,188 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	175,820,392 - 175,821,159 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	171,763,869 - 171,764,636 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	5	171,774,363 - 171,775,131 (+)	NCBI
Celera	5	163,728,713 - 163,729,480 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

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QTLs in Region (Rnor_6.0)

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RNA-SEQ Expression

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Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

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Nomenclature History

RGD Curation Notes

More on Hes5
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: rn5 rn6
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	621340
Created:	2002-08-06
Species:	Rattus norvegicus
Last Modified:	2020-08-20
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Annotations - ClinVar

Imported Annotations - CTD

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Imported Annotations - KEGG (archival)