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Gene: Sfn (stratifin) Rattus norvegicus
Symbol: Sfn
Name: stratifin
Description: Predicted to have identical protein binding activity; phosphoprotein binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of cellular protein metabolic process; and skin development. Predicted to localize to cytosol and nucleus. Human ortholog(s) of this gene implicated in transitional cell carcinoma and vulva squamous cell carcinoma. Orthologous to human SFN (stratifin); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2-acetamidofluorene; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: 14-3-3 protein sigma; LOC313017
Homo sapiens (human) : SFN (stratifin)  HGNC  Alliance
Mus musculus (house mouse) : Sfn (stratifin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sfn (stratifin)
Pan paniscus (bonobo/pygmy chimpanzee) : SFN (stratifin)
Canis lupus familiaris (dog) : SFN (stratifin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sfn (stratifin)
Chlorocebus sabaeus (African green monkey) : SFN (stratifin)
Heterocephalus glaber (naked mole-rat) : Sfn (stratifin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05151,823,422 - 151,824,937 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5151,823,887 - 151,824,633 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05155,512,802 - 155,514,320 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45151,475,395 - 151,479,996 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15151,485,433 - 151,490,434 (+)NCBI
Celera5144,247,261 - 144,248,776 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Sfn
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304729
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.