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Gene: Sfn (stratifin) Rattus norvegicus
Symbol: Sfn
Name: stratifin
Description: Predicted to have identical protein binding activity; phosphoprotein binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of cellular protein metabolic process; and skin development. Predicted to localize to the cytosol and nucleus. Human ortholog(s) of this gene implicated in transitional cell carcinoma and vulva squamous cell carcinoma. Orthologous to human SFN (stratifin); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2-acetamidofluorene; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: 14-3-3 protein sigma; LOC313017
Homo sapiens (human) : SFN (stratifin)  HGNC  Alliance
Mus musculus (house mouse) : Sfn (stratifin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sfn (stratifin)
Pan paniscus (bonobo/pygmy chimpanzee) : SFN (stratifin)
Canis lupus familiaris (dog) : SFN (stratifin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sfn (stratifin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05151,823,422 - 151,824,937 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05155,512,802 - 155,514,320 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45151,475,395 - 151,479,996 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15151,485,433 - 151,490,434 (+)NCBI
Celera5144,247,261 - 144,248,776 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Sfn
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304729
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.