Mad2l2 (mitotic arrest deficient 2 like 2) - Rat Genome Database

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Gene: Mad2l2 (mitotic arrest deficient 2 like 2) Rattus norvegicus
Analyze
Symbol: Mad2l2
Name: mitotic arrest deficient 2 like 2
RGD ID: 1307499
Description: Predicted to enable JUN kinase binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in several processes, including DNA repair; regulation of nucleobase-containing compound metabolic process; and regulation of protein metabolic process. Predicted to be located in cytosol; nucleolus; and spindle. Predicted to be part of zeta DNA polymerase complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group V. Orthologous to human MAD2L2 (mitotic arrest deficient 2 like 2); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC313702; MAD2 mitotic arrest deficient-like 2; MAD2 mitotic arrest deficient-like 2 (yeast); MAD2-like protein 2; mitotic arrest deficient 2-like protein 2; mitotic spindle assembly checkpoint protein MAD2B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25158,563,545 - 158,576,698 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl5158,563,567 - 158,576,693 (+)Ensembl
Rnor_6.05164,943,183 - 164,956,255 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,950,917 - 164,956,255 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05168,601,233 - 168,614,293 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45165,218,362 - 165,222,828 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15165,228,549 - 165,233,014 (+)NCBI
Celera5156,851,516 - 156,855,981 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
anaphase-promoting complex  (ISO,ISS)
cytosol  (IEA,ISO)
nucleolus  (IEA,ISO)
nucleus  (ISO,ISS)
spindle  (ISO,ISS)
zeta DNA polymerase complex  (IBA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2. Tang H, etal., J Mol Med (Berl). 2016 Nov;94(11):1297-1307. doi: 10.1007/s00109-016-1448-6. Epub 2016 Aug 3.
Additional References at PubMed
PMID:11459825   PMID:11459826   PMID:12477932   PMID:15988022   PMID:17296730   PMID:17541814   PMID:19443654   PMID:20164194   PMID:21063390   PMID:24444371   PMID:25651564   PMID:27957796  
PMID:29656893  


Genomics

Comparative Map Data
Mad2l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25158,563,545 - 158,576,698 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl5158,563,567 - 158,576,693 (+)Ensembl
Rnor_6.05164,943,183 - 164,956,255 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,950,917 - 164,956,255 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05168,601,233 - 168,614,293 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45165,218,362 - 165,222,828 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15165,228,549 - 165,233,014 (+)NCBI
Celera5156,851,516 - 156,855,981 (+)NCBICelera
Cytogenetic Map5q36NCBI
MAD2L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,674,480 - 11,691,830 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl111,658,918 - 11,691,811 (-)EnsemblGRCh38hg38GRCh38
GRCh37111,734,537 - 11,751,616 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,657,124 - 11,663,780 (-)NCBINCBI36hg18NCBI36
Build 34111,668,802 - 11,675,459NCBI
Celera110,846,601 - 10,863,739 (-)NCBI
Cytogenetic Map1p36.22NCBI
HuRef110,888,642 - 10,905,769 (-)NCBIHuRef
CHM1_1111,722,539 - 11,739,685 (-)NCBICHM1_1
T2T-CHM13v2.0111,218,548 - 11,235,614 (-)NCBI
Mad2l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394148,214,615 - 148,230,161 (+)NCBIGRCm39mm39
GRCm39 Ensembl4148,214,841 - 148,230,156 (+)Ensembl
GRCm384148,130,158 - 148,145,704 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4148,130,384 - 148,145,699 (+)EnsemblGRCm38mm10GRCm38
MGSCv374147,514,599 - 147,519,805 (+)NCBIGRCm37mm9NCBIm37
MGSCv364146,984,290 - 146,989,496 (+)NCBImm8
Celera4150,401,823 - 150,407,027 (+)NCBICelera
Cytogenetic Map4E2NCBI
Mad2l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554862,191,903 - 2,198,538 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554862,191,903 - 2,197,193 (+)NCBIChiLan1.0ChiLan1.0
MAD2L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1111,654,963 - 11,671,364 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,654,963 - 11,661,526 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0110,436,532 - 10,454,023 (-)NCBIMhudiblu_PPA_v0panPan3
MAD2L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1284,539,724 - 84,549,402 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl284,545,226 - 84,549,356 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,076,962 - 81,081,699 (+)NCBI
ROS_Cfam_1.0285,207,730 - 85,212,516 (+)NCBI
ROS_Cfam_1.0 Ensembl285,201,068 - 85,212,508 (+)Ensembl
UMICH_Zoey_3.1281,956,536 - 81,961,266 (+)NCBI
UNSW_CanFamBas_1.0282,957,166 - 82,961,884 (+)NCBI
UU_Cfam_GSD_1.0284,020,037 - 84,024,757 (+)NCBI
Mad2l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505834,713,906 - 34,718,120 (-)NCBI
SpeTri2.0NW_004936474538,703 - 542,901 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAD2L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl671,773,682 - 71,779,183 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1671,773,680 - 71,779,192 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2665,692,635 - 65,698,160 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAD2L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120120,099,928 - 120,115,954 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl20120,110,269 - 120,116,083 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605423,977,591 - 23,984,254 (+)NCBIVero_WHO_p1.0
Mad2l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248181,282,082 - 1,286,997 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248181,274,553 - 1,286,750 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH132073  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25158,576,197 - 158,576,498 (+)MAPPERmRatBN7.2
Rnor_6.05164,955,755 - 164,956,055NCBIRnor6.0
Rnor_5.05168,613,793 - 168,614,093UniSTSRnor5.0
RGSC_v3.45165,222,328 - 165,222,628UniSTSRGSC3.4
Celera5156,855,481 - 156,855,781UniSTS
RH 3.4 Map51107.5UniSTS
Cytogenetic Map5q36UniSTS
RH133258  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25158,576,936 - 158,577,117 (+)MAPPERmRatBN7.2
Rnor_6.05164,956,494 - 164,956,674NCBIRnor6.0
Rnor_5.05168,614,532 - 168,614,712UniSTSRnor5.0
RGSC_v3.45165,223,067 - 165,223,247UniSTSRGSC3.4
Celera5156,856,220 - 156,856,400UniSTS
RH 3.4 Map51104.4UniSTS
Cytogenetic Map5q36UniSTS
Mad2l2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25158,572,165 - 158,572,310 (+)MAPPERmRatBN7.2
Rnor_6.05164,951,723 - 164,951,867NCBIRnor6.0
Rnor_5.05168,609,761 - 168,609,905UniSTSRnor5.0
Celera5156,851,450 - 156,851,594UniSTS
Cytogenetic Map5q36UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:56
Interacting mature miRNAs:60
Transcripts:ENSRNOT00000012193, ENSRNOT00000055658
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 31 27 20 12 20 1 64 27 40 10
Low 12 30 21 7 21 8 10 10 8 1 1 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000012193   ⟹   ENSRNOP00000012193
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5164,951,874 - 164,956,248 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000055658   ⟹   ENSRNOP00000052521
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5158,563,567 - 158,576,677 (+)Ensembl
Rnor_6.0 Ensembl5164,951,789 - 164,956,255 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076305   ⟹   ENSRNOP00000068004
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5164,951,768 - 164,954,766 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083678   ⟹   ENSRNOP00000070808
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5158,563,576 - 158,576,693 (+)Ensembl
Rnor_6.0 Ensembl5164,950,917 - 164,956,147 (+)Ensembl
RefSeq Acc Id: NM_001012106   ⟹   NP_001012106
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25158,572,232 - 158,576,698 (+)NCBI
Rnor_6.05164,951,789 - 164,956,255 (+)NCBI
Rnor_5.05168,601,233 - 168,614,293 (+)NCBI
RGSC_v3.45165,218,362 - 165,222,828 (+)RGD
Celera5156,851,516 - 156,855,981 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239390   ⟹   XP_006239452
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25158,563,566 - 158,576,693 (+)NCBI
Rnor_6.05164,943,183 - 164,956,235 (+)NCBI
Rnor_5.05168,601,233 - 168,614,293 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239391   ⟹   XP_006239453
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25158,571,984 - 158,576,693 (+)NCBI
Rnor_6.05164,951,119 - 164,956,235 (+)NCBI
Rnor_5.05168,601,233 - 168,614,293 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008764256   ⟹   XP_008762478
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25158,571,232 - 158,576,693 (+)NCBI
Rnor_6.05164,950,625 - 164,956,235 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039110094   ⟹   XP_038966022
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25158,567,042 - 158,576,693 (+)NCBI
RefSeq Acc Id: XM_039110095   ⟹   XP_038966023
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25158,563,545 - 158,576,693 (+)NCBI
RefSeq Acc Id: XM_039110096   ⟹   XP_038966024
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25158,571,313 - 158,576,693 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001012106   ⟸   NM_001012106
- UniProtKB: D3Z8D9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006239452   ⟸   XM_006239390
- Peptide Label: isoform X1
- UniProtKB: D3Z8D9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006239453   ⟸   XM_006239391
- Peptide Label: isoform X2
- UniProtKB: D3Z8D9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008762478   ⟸   XM_008764256
- Peptide Label: isoform X1
- UniProtKB: D3Z8D9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000052521   ⟸   ENSRNOT00000055658
RefSeq Acc Id: ENSRNOP00000012193   ⟸   ENSRNOT00000012193
RefSeq Acc Id: ENSRNOP00000070808   ⟸   ENSRNOT00000083678
RefSeq Acc Id: ENSRNOP00000068004   ⟸   ENSRNOT00000076305
RefSeq Acc Id: XP_038966023   ⟸   XM_039110095
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038966022   ⟸   XM_039110094
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038966024   ⟸   XM_039110096
- Peptide Label: isoform X2
Protein Domains
HORMA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z8D9-F1-model_v2 AlphaFold D3Z8D9 1-211 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694264
Promoter ID:EPDNEW_R4782
Type:multiple initiation site
Name:Mad2l2_1
Description:mitotic arrest deficient 2 like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05164,951,770 - 164,951,830EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307499 AgrOrtholog
BioCyc Gene G2FUF-39175 BioCyc
Ensembl Genes ENSRNOG00000009134 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000052521 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000070808 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000055658 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000083678 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.900.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7307981 IMAGE-MGC_LOAD
InterPro HORMA_dom UniProtKB/Swiss-Prot
  HORMA_dom_sf UniProtKB/Swiss-Prot
  Mad2-like UniProtKB/Swiss-Prot
KEGG Report rno:313702 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105558 IMAGE-MGC_LOAD
NCBI Gene 313702 ENTREZGENE
PANTHER PTHR11842 UniProtKB/Swiss-Prot
Pfam HORMA UniProtKB/Swiss-Prot
PhenoGen Mad2l2 PhenoGen
PROSITE HORMA UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56019 UniProtKB/Swiss-Prot
UniProt D3Z8D9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q5PPH8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-29 Mad2l2  mitotic arrest deficient 2 like 2  Mad2l2  MAD2 mitotic arrest deficient-like 2 (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Mad2l2  MAD2 mitotic arrest deficient-like 2 (yeast)  Mad2l2_predicted  MAD2 mitotic arrest deficient-like 2 (yeast) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Mad2l2_predicted  MAD2 mitotic arrest deficient-like 2 (yeast) (predicted)      Symbol and Name status set to approved 70820 APPROVED