Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Htr6 (5-hydroxytryptamine receptor 6) Rattus norvegicus
Symbol: Htr6
Name: 5-hydroxytryptamine receptor 6
Description: Exhibits G protein-coupled serotonin receptor activity. Involved in several processes, including long-term synaptic potentiation; regulation of amine transport; and response to estradiol. Localizes to dendrite and plasma membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human HTR6 (5-hydroxytryptamine receptor 6); PARTICIPATES IN serotonin signaling pathway via receptors engaging G alphas protein family; calcium/calcium-mediated signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5-HT-6; 5-HT6; 5-hydroxytryptamine (serotonin) receptor 6; 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled; serotonin receptor 6; ST-B17
Homo sapiens (human) : HTR6 (5-hydroxytryptamine receptor 6)  HGNC  Alliance
Mus musculus (house mouse) : Htr6 (5-hydroxytryptamine (serotonin) receptor 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr6 (5-hydroxytryptamine receptor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR6 (5-hydroxytryptamine receptor 6)
Canis lupus familiaris (dog) : HTR6 (5-hydroxytryptamine receptor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htr6 (5-hydroxytryptamine receptor 6)
Sus scrofa (pig) : HTR6 (5-hydroxytryptamine receptor 6)
Chlorocebus sabaeus (African green monkey) : HTR6 (5-hydroxytryptamine receptor 6)
Heterocephalus glaber (naked mole-rat) : Htr6 (5-hydroxytryptamine receptor 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05157,501,202 - 157,518,870 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,503,040 - 157,518,631 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05161,242,331 - 161,257,707 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5149,681,578 - 149,696,742 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Htr6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62044
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.