Nmnat1 (nicotinamide nucleotide adenylyltransferase 1) - Rat Genome Database
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Gene: Nmnat1 (nicotinamide nucleotide adenylyltransferase 1) Rattus norvegicus
Analyze
Symbol: Nmnat1
Name: nicotinamide nucleotide adenylyltransferase 1
RGD ID: 1310996
Description: Predicted to have identical protein binding activity; nicotinamide-nucleotide adenylyltransferase activity; and nicotinate-nucleotide adenylyltransferase activity. Involved in negative regulation of apoptotic DNA fragmentation; negative regulation of neuron apoptotic process; and positive regulation of MAPK cascade. Localizes to cytoplasm and nucleus. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 9. Orthologous to human NMNAT1 (nicotinamide nucleotide adenylyltransferase 1); PARTICIPATES IN de novo nicotinamide adenine dinucleotide biosynthetic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; monoterpenoid biosynthetic pathway; INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC298653; MGC156478; nicotinamide mononucleotide adenylyl transferase 1; nicotinamide mononucleotide adenylyltransferase 1; nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
Orthologs:
Homo sapiens (human) : NMNAT1 (nicotinamide nucleotide adenylyltransferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Nmnat1 (nicotinamide nucleotide adenylyltransferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nmnat1 (nicotinamide nucleotide adenylyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NMNAT1 (nicotinamide nucleotide adenylyltransferase 1)
Canis lupus familiaris (dog) : NMNAT1 (nicotinamide nucleotide adenylyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nmnat1 (nicotinamide nucleotide adenylyltransferase 1)
Sus scrofa (pig) : NMNAT1 (nicotinamide nucleotide adenylyltransferase 1)
Chlorocebus sabaeus (African green monkey) : NMNAT1 (nicotinamide nucleotide adenylyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Nmnat1 (nicotinamide nucleotide adenylyltransferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05166,409,460 - 166,430,291 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5166,409,461 - 166,430,254 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05170,057,406 - 170,076,545 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45166,548,899 - 166,567,266 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15166,560,236 - 166,569,740 (-)NCBI
Celera5158,179,840 - 158,197,813 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA)
nuclear body  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IDA,ISO)

Molecular Function

References

Additional References at PubMed
PMID:11027696   PMID:11248244   PMID:12477932   PMID:15381699   PMID:16118205   PMID:17074042   PMID:18783366   PMID:21516116   PMID:21630459   PMID:22365601   PMID:25416956   PMID:25502805  
PMID:27257257   PMID:27735788   PMID:31515488  


Genomics

Comparative Map Data
Nmnat1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05166,409,460 - 166,430,291 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5166,409,461 - 166,430,254 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05170,057,406 - 170,076,545 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45166,548,899 - 166,567,266 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15166,560,236 - 166,569,740 (-)NCBI
Celera5158,179,840 - 158,197,813 (-)NCBICelera
Cytogenetic Map5q36NCBI
NMNAT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl19,943,428 - 9,985,501 (+)EnsemblGRCh38hg38GRCh38
GRCh3819,942,923 - 9,996,884 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37110,003,486 - 10,045,556 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619,926,073 - 9,968,143 (+)NCBINCBI36hg18NCBI36
Build 3419,937,752 - 9,977,979NCBI
Celera19,114,519 - 9,156,598 (+)NCBI
Cytogenetic Map1p36.22NCBI
HuRef19,158,939 - 9,200,537 (+)NCBIHuRef
CHM1_119,991,798 - 10,034,914 (+)NCBICHM1_1
Nmnat1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394149,552,026 - 149,569,667 (-)NCBI
GRCm384149,467,569 - 149,485,210 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4149,467,572 - 149,485,202 (-)EnsemblGRCm38mm10GRCm38
MGSCv374148,842,896 - 148,859,251 (-)NCBIGRCm37mm9NCBIm37
MGSCv364148,312,587 - 148,328,942 (-)NCBImm8
Celera4151,732,264 - 151,748,554 (-)NCBICelera
Cytogenetic Map4E2NCBI
Nmnat1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554863,637,794 - 3,655,598 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554863,637,794 - 3,655,744 (-)NCBIChiLan1.0ChiLan1.0
NMNAT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.119,942,491 - 9,982,369 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl19,942,491 - 9,982,364 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v018,712,798 - 8,753,027 (+)NCBIMhudiblu_PPA_v0panPan3
NMNAT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl563,122,498 - 63,151,661 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1563,122,379 - 63,152,078 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Nmnat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366233,862,234 - 3,891,849 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NMNAT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl670,272,030 - 70,310,603 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1670,271,296 - 70,307,403 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2664,326,981 - 64,334,151 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NMNAT1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120121,790,836 - 121,797,043 (-)NCBI
Nmnat1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248182,575,476 - 2,591,423 (-)NCBI

Position Markers
D5Uwm49  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.05166,409,918 - 166,410,170NCBIRnor6.0
Rnor_5.05170,057,864 - 170,058,116UniSTSRnor5.0
RGSC_v3.45166,549,356 - 166,549,609RGDRGSC3.4
RGSC_v3.45166,549,357 - 166,549,609UniSTSRGSC3.4
RGSC_v3.15166,559,544 - 166,559,797RGD
Celera5158,180,298 - 158,180,550UniSTS
Cytogenetic Map5q36UniSTS
RH134246  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.05166,409,544 - 166,409,756NCBIRnor6.0
Rnor_5.05170,057,490 - 170,057,702UniSTSRnor5.0
RGSC_v3.45166,548,983 - 166,549,195UniSTSRGSC3.4
Celera5158,179,924 - 158,180,136UniSTS
Cytogenetic Map5q36UniSTS
RH 3.4 Map51116.8UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5149568588167739697Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5142309061173707219Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132551937173707219Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149029982173687766Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5157212422167739539Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5142307322173707219Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5136354114173707219Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5157319671173707219Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138154677172402610Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)584963058173504662Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5128687766173687766Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133943857173707219Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133943857173707219Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5134197905173707219Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)547745646167946134Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5157319671171194163Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5161084664173707219Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5150360936167946134Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)561612600168109659Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136640731173707219Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5134712342173707219Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5134712342173707219Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5131077716173707219Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:503
Count of miRNA genes:244
Interacting mature miRNAs:294
Transcripts:ENSRNOT00000048914
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 34 20 15 3 15 2 51 24 29 5
Low 9 37 26 16 26 8 9 23 11 12 6 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000048914   ⟹   ENSRNOP00000041982
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5166,409,461 - 166,430,254 (-)Ensembl
RefSeq Acc Id: NM_001037556   ⟹   NP_001032645
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05166,409,460 - 166,430,254 (-)NCBI
Rnor_5.05170,057,406 - 170,076,545 (-)NCBI
RGSC_v3.45166,548,899 - 166,567,266 (-)RGD
Celera5158,179,840 - 158,197,813 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239429   ⟹   XP_006239491
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05166,410,350 - 166,429,735 (-)NCBI
Rnor_5.05170,057,406 - 170,076,545 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239431   ⟹   XP_006239493
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05166,410,350 - 166,430,086 (-)NCBI
Rnor_5.05170,057,406 - 170,076,545 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764237   ⟹   XP_008762459
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05166,410,350 - 166,430,291 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764238   ⟹   XP_008762460
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05166,410,350 - 166,421,965 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593311   ⟹   XP_017448800
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05166,410,350 - 166,423,147 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001032645   ⟸   NM_001037556
- UniProtKB: A0JPJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239493   ⟸   XM_006239431
- Peptide Label: isoform X2
- UniProtKB: A0JPJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239491   ⟸   XM_006239429
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008762459   ⟸   XM_008764237
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008762460   ⟸   XM_008764238
- Peptide Label: isoform X2
- UniProtKB: A0JPJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448800   ⟸   XM_017593311
- Peptide Label: isoform X2
- UniProtKB: A0JPJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000041982   ⟸   ENSRNOT00000048914
Protein Domains
CTP_transf_like

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694272
Promoter ID:EPDNEW_R4797
Type:multiple initiation site
Name:Nmnat1_1
Description:nicotinamide nucleotide adenylyltransferase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05166,430,277 - 166,430,337EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310996 AgrOrtholog
Ensembl Genes ENSRNOG00000015962 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000041982 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048914 ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7383226 IMAGE-MGC_LOAD
InterPro Cyt_trans-like UniProtKB/TrEMBL
  NAMN_adtrnsfrase UniProtKB/TrEMBL
KEGG Report rno:298653 UniProtKB/TrEMBL
MGC_CLONE MGC:156478 IMAGE-MGC_LOAD
NCBI Gene 298653 ENTREZGENE
Pfam CTP_transf_2 UniProtKB/TrEMBL
PhenoGen Nmnat1 PhenoGen
TIGRFAMs TIGR00482 UniProtKB/TrEMBL
UniGene Rn.147523 ENTREZGENE
UniProt A0JPJ0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary E9PSK8 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Nmnat1  nicotinamide nucleotide adenylyltransferase 1  Nmnat1_predicted  nicotinamide nucleotide adenylyltransferase 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Nmnat1_predicted  nicotinamide nucleotide adenylyltransferase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED