Gene: Clcnka (chloride voltage-gated channel Ka) Rattus norvegicus
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Symbol: Clcnka
Name: chloride voltage-gated channel Ka
Description: ENCODES a protein that exhibits chloride channel activity; voltage-gated ion channel activity; identical protein binding (ortholog); INVOLVED IN body fluid secretion; kidney development; response to calcium ion; PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH Bartter disease type 3 (ortholog); Bartter disease type 4b (ortholog); Deafness (ortholog); FOUND IN apical plasma membrane; basolateral plasma membrane; endoplasmic reticulum; INTERACTS WITH (4-chloro-2-methylphenoxy)acetic acid; 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: chloride channel K1; chloride channel Ka; chloride channel protein ClC-Ka; chloride channel, voltage-sensitive Ka; clC-K1; Clcnk1; MGC93313
Orthologs:
Homo sapiens (human) : CLCNKA (chloride voltage-gated channel Ka)  HGNC  Alliance
Mus musculus (house mouse) : Clcnka (chloride channel, voltage-sensitive Ka)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CLCNKA (chloride voltage-gated channel Ka)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcnka (chloride voltage-gated channel Ka)
Sus scrofa (pig) : CLCNKA (chloride channel protein ClC-Ka)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05159,931,497 - 159,946,483 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05163,651,964 - 163,667,008 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45160,274,377 - 160,290,369 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15160,284,564 - 160,300,557 (-)NCBI
Celera5152,055,371 - 152,067,986 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Clcnka
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68435
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE