Heyl (hes-related family bHLH transcription factor with YRPW motif-like) - Rat Genome Database

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Gene: Heyl (hes-related family bHLH transcription factor with YRPW motif-like) Rattus norvegicus
Analyze
Symbol: Heyl
Name: hes-related family bHLH transcription factor with YRPW motif-like
RGD ID: 1305022
Description: Predicted to enable several functions, including AF-1 domain binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and protein homodimerization activity. Predicted to be involved in several processes, including heart development; nephron development; and regulation of DNA-templated transcription. Predicted to act upstream of or within epithelial to mesenchymal transition involved in endocardial cushion formation; negative regulation of gene expression; and skeletal muscle cell differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human HEYL (hes related family bHLH transcription factor with YRPW motif like); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hairy/enhancer-of-split related with YRPW motif-like; LOC313575
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85140,793,271 - 140,810,262 (+)NCBIGRCr8
GRCr8 Ensembl5140,793,271 - 140,810,262 (+)EnsemblGRCr8 Ensembl
mRatBN7.25135,508,160 - 135,525,152 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5135,508,160 - 135,525,152 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5138,214,573 - 138,231,698 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05139,984,540 - 140,001,666 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05139,991,677 - 140,008,802 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05140,923,914 - 140,940,905 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5140,923,914 - 140,940,905 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05144,713,817 - 144,730,808 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45142,544,185 - 142,561,176 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5134,047,073 - 134,064,064 (+)NCBICelera
RGSC_v3.15142,549,721 - 142,563,036 (+)NCBI
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Delta-Notch--and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Fischer A and Gessler M, Nucleic Acids Res. 2007;35(14):4583-96. Epub 2007 Jun 22.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Coordinate Notch3-hairy-related transcription factor pathway regulation in response to arterial injury. Mediator role of platelet-derived growth factor and ERK. Wang W, etal., J Biol Chem 2002 Jun 28;277(26):23165-71.
Additional References at PubMed
PMID:10964718   PMID:15485867   PMID:15821257   PMID:16199874   PMID:17303760   PMID:19631204   PMID:21259317   PMID:21290414   PMID:21454491   PMID:22147266   PMID:22615585  


Genomics

Comparative Map Data
Heyl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85140,793,271 - 140,810,262 (+)NCBIGRCr8
GRCr8 Ensembl5140,793,271 - 140,810,262 (+)EnsemblGRCr8 Ensembl
mRatBN7.25135,508,160 - 135,525,152 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5135,508,160 - 135,525,152 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5138,214,573 - 138,231,698 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05139,984,540 - 140,001,666 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05139,991,677 - 140,008,802 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05140,923,914 - 140,940,905 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5140,923,914 - 140,940,905 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05144,713,817 - 144,730,808 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45142,544,185 - 142,561,176 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5134,047,073 - 134,064,064 (+)NCBICelera
RGSC_v3.15142,549,721 - 142,563,036 (+)NCBI
Cytogenetic Map5q36NCBI
HEYL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38139,623,435 - 39,639,643 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl139,623,435 - 39,639,643 (-)EnsemblGRCh38hg38GRCh38
GRCh37140,089,107 - 40,105,315 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36139,861,690 - 39,877,935 (-)NCBINCBI36Build 36hg18NCBI36
Build 34139,758,917 - 39,774,411NCBI
Celera138,370,855 - 38,387,100 (-)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef138,207,488 - 38,223,733 (-)NCBIHuRef
CHM1_1140,204,476 - 40,220,725 (-)NCBICHM1_1
T2T-CHM13v2.0139,487,908 - 39,508,063 (-)NCBIT2T-CHM13v2.0
Heyl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394123,127,349 - 123,143,663 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4123,127,349 - 123,143,668 (+)EnsemblGRCm39 Ensembl
GRCm384123,233,556 - 123,249,870 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4123,233,556 - 123,249,875 (+)EnsemblGRCm38mm10GRCm38
MGSCv374122,910,799 - 122,927,113 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364122,736,156 - 122,752,173 (+)NCBIMGSCv36mm8
Celera4121,565,928 - 121,582,239 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map457.41NCBI
Heyl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545217,134,770 - 17,152,924 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545217,137,066 - 17,152,714 (-)NCBIChiLan1.0ChiLan1.0
HEYL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21187,182,481 - 187,198,009 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11186,320,121 - 186,335,647 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0138,913,549 - 38,929,798 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1140,240,114 - 40,256,300 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl140,240,118 - 40,256,933 (-)Ensemblpanpan1.1panPan2
Heyl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505855,678,981 - 55,688,610 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647421,505,149 - 21,510,624 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647421,503,763 - 21,513,392 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HEYL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl695,442,661 - 95,459,575 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1695,442,655 - 95,459,597 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2688,532,056 - 88,547,809 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HEYL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12093,230,189 - 93,246,549 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603323,571,967 - 23,587,587 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Heyl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476422,122,079 - 22,135,252 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476422,118,995 - 22,135,280 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Heyl
68 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:746
Count of miRNA genes:284
Interacting mature miRNAs:378
Transcripts:ENSRNOT00000020929
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5130678987145274255Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5134369218156289444Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125969677156302135Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
7411722Strs6Sensitivity to stroke QTL 63.9cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)5140258140143398122Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
D4Mit11  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8492,690,519 - 92,690,793 (+)Marker Load Pipeline
mRatBN7.2491,360,527 - 91,360,801 (+)MAPPERmRatBN7.2
Rnor_6.0492,484,039 - 92,484,312NCBIRnor6.0
Rnor_5.04157,291,086 - 157,291,359UniSTSRnor5.0
RGSC_v3.4491,330,582 - 91,330,856RGDRGSC3.4
RGSC_v3.4491,330,583 - 91,330,856UniSTSRGSC3.4
Celera486,134,746 - 86,135,019UniSTS
RGSC_v3.1491,575,008 - 91,575,281RGD
RH 3.4 Map4577.9RGD
RH 3.4 Map4577.9UniSTS
RH 2.0 Map4591.5RGD
Cytogenetic Map5q36UniSTS
RH137535  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85140,802,653 - 140,802,806 (+)Marker Load Pipeline
mRatBN7.25135,517,542 - 135,517,695 (+)MAPPERmRatBN7.2
Rnor_6.05140,933,297 - 140,933,449NCBIRnor6.0
Rnor_5.05144,723,200 - 144,723,352UniSTSRnor5.0
RGSC_v3.45142,553,568 - 142,553,720UniSTSRGSC3.4
Celera5134,056,456 - 134,056,608UniSTS
Cytogenetic Map5q36UniSTS
RH143142  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25135,516,105 - 135,516,206 (+)MAPPERmRatBN7.2
Rnor_6.05140,931,860 - 140,931,960NCBIRnor6.0
Rnor_5.05144,721,763 - 144,721,863UniSTSRnor5.0
RGSC_v3.45142,552,131 - 142,552,231UniSTSRGSC3.4
Celera5134,055,019 - 134,055,119UniSTS
RH 3.4 Map5889.8UniSTS
Cytogenetic Map5q36UniSTS
RH143336  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25135,523,274 - 135,523,417 (+)MAPPERmRatBN7.2
Rnor_6.05140,939,029 - 140,939,171NCBIRnor6.0
Rnor_5.05144,728,932 - 144,729,074UniSTSRnor5.0
RGSC_v3.45142,559,300 - 142,559,442UniSTSRGSC3.4
Celera5134,062,188 - 134,062,330UniSTS
RH 3.4 Map5889.8UniSTS
Cytogenetic Map5q36UniSTS
BG378118  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25135,524,668 - 135,524,848 (+)MAPPERmRatBN7.2
Rnor_6.05140,940,422 - 140,940,601NCBIRnor6.0
Rnor_5.05144,730,325 - 144,730,504UniSTSRnor5.0
RGSC_v3.45142,560,693 - 142,560,872UniSTSRGSC3.4
Celera5134,063,581 - 134,063,760UniSTS
RH 3.4 Map5875.6UniSTS
Cytogenetic Map5q36UniSTS
BE100438  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25135,521,935 - 135,522,102 (+)MAPPERmRatBN7.2
Rnor_6.05140,937,690 - 140,937,856NCBIRnor6.0
Rnor_5.05144,727,593 - 144,727,759UniSTSRnor5.0
RGSC_v3.45142,557,961 - 142,558,127UniSTSRGSC3.4
Celera5134,060,849 - 134,061,015UniSTS
RH 3.4 Map5889.8UniSTS
Cytogenetic Map5q36UniSTS
D4Mit11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25135,507,899 - 135,508,022 (+)MAPPERmRatBN7.2
Rnor_6.05140,923,654 - 140,923,776NCBIRnor6.0
Rnor_5.05144,713,557 - 144,713,679UniSTSRnor5.0
RGSC_v3.45142,543,925 - 142,544,047UniSTSRGSC3.4
Celera5134,046,813 - 134,046,935UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 49 113 91 90 59 25 59 6 218 97 11 93 45 60 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020929   ⟹   ENSRNOP00000020928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5140,793,271 - 140,810,262 (+)Ensembl
mRatBN7.2 Ensembl5135,508,160 - 135,525,152 (+)Ensembl
Rnor_6.0 Ensembl5140,923,914 - 140,940,905 (+)Ensembl
RefSeq Acc Id: NM_001107977   ⟹   NP_001101447
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85140,793,271 - 140,810,262 (+)NCBI
mRatBN7.25135,508,160 - 135,525,152 (+)NCBI
Rnor_6.05140,923,914 - 140,940,905 (+)NCBI
Rnor_5.05144,713,817 - 144,730,808 (+)NCBI
RGSC_v3.45142,544,185 - 142,561,176 (+)RGD
Celera5134,047,073 - 134,064,064 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001101447 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL80374 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020928
  ENSRNOP00000020928.2
RefSeq Acc Id: NP_001101447   ⟸   NM_001107977
- UniProtKB: D3ZIH3 (UniProtKB/TrEMBL),   A6IS23 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020928   ⟸   ENSRNOT00000020929
Protein Domains
bHLH   Orange

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIH3-F1-model_v2 AlphaFold D3ZIH3 1-326 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305022 AgrOrtholog
BioCyc Gene G2FUF-40014 BioCyc
Ensembl Genes ENSRNOG00000015318 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020929 ENTREZGENE
  ENSRNOT00000020929.4 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
  6.10.250.980 UniProtKB/TrEMBL
InterPro HES_HEY UniProtKB/TrEMBL
  HLH_DNA-bd UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  Orange UniProtKB/TrEMBL
KEGG Report rno:313575 UniProtKB/TrEMBL
NCBI Gene 313575 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED UniProtKB/TrEMBL
Pfam Hairy_orange UniProtKB/TrEMBL
  HLH UniProtKB/TrEMBL
PhenoGen Heyl PhenoGen
PROSITE HLH UniProtKB/TrEMBL
  ORANGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015318 RatGTEx
SMART HLH UniProtKB/TrEMBL
  ORANGE UniProtKB/TrEMBL
Superfamily-SCOP HLH_basic UniProtKB/TrEMBL
  Orange domain-like UniProtKB/TrEMBL
UniProt A6IS23 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIH3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-11 Heyl  hes-related family bHLH transcription factor with YRPW motif-like  Heyl  hairy/enhancer-of-split related with YRPW motif-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Heyl  hairy/enhancer-of-split related with YRPW motif-like   Heyl_predicted  hairy/enhancer-of-split related with YRPW motif-like (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Heyl_predicted  hairy/enhancer-of-split related with YRPW motif-like (predicted)      Symbol and Name status set to approved 70820 APPROVED