Mrpl20 (mitochondrial ribosomal protein L20) - Rat Genome Database

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Gene: Mrpl20 (mitochondrial ribosomal protein L20) Rattus norvegicus
Analyze
Symbol: Mrpl20
Name: mitochondrial ribosomal protein L20
RGD ID: 1588219
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrial ribosome. Orthologous to human MRPL20 (mitochondrial ribosomal protein L20); INTERACTS WITH acetamide; aconitine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 39S ribosomal protein L20, mitochondrial; large ribosomal subunit protein bL20m; LOC680747; similar to mitochondrial ribosomal protein L20
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,690,664 - 171,695,728 (+)NCBIGRCr8
mRatBN7.25166,408,962 - 166,413,492 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,408,962 - 166,413,492 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5169,113,837 - 169,118,373 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05170,935,256 - 170,939,792 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05170,897,787 - 170,902,323 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,248,245 - 173,252,775 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,248,245 - 173,252,775 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05176,723,859 - 176,728,389 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,657,923 - 172,662,453 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5164,609,698 - 164,614,228 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
translation  (IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:18614015   PMID:20601428   PMID:22681889   PMID:25278503   PMID:28892042  


Genomics

Comparative Map Data
Mrpl20
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,690,664 - 171,695,728 (+)NCBIGRCr8
mRatBN7.25166,408,962 - 166,413,492 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,408,962 - 166,413,492 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5169,113,837 - 169,118,373 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05170,935,256 - 170,939,792 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05170,897,787 - 170,902,323 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,248,245 - 173,252,775 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,248,245 - 173,252,775 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05176,723,859 - 176,728,389 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,657,923 - 172,662,453 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5164,609,698 - 164,614,228 (+)NCBICelera
Cytogenetic Map5q36NCBI
MRPL20
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811,401,909 - 1,407,293 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11,401,909 - 1,407,293 (-)EnsemblGRCh38hg38GRCh38
GRCh3711,337,289 - 1,342,673 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,327,159 - 1,332,524 (-)NCBINCBI36Build 36hg18NCBI36
Celera11,238,564 - 1,243,981 (+)NCBICelera
Cytogenetic Map1p36.33NCBI
HuRef1609,481 - 614,898 (-)NCBIHuRef
CHM1_111,324,690 - 1,330,107 (-)NCBICHM1_1
T2T-CHM13v2.01833,839 - 839,223 (-)NCBIT2T-CHM13v2.0
Mrpl20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,887,335 - 155,893,288 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4155,887,335 - 155,894,432 (+)EnsemblGRCm39 Ensembl
GRCm384155,802,878 - 155,808,831 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,802,878 - 155,809,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv374155,177,727 - 155,182,938 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364154,647,418 - 154,652,629 (+)NCBIMGSCv36mm8
Celera4158,074,686 - 158,080,132 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map487.44NCBI
Mrpl20
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554869,417,925 - 9,420,789 (+)NCBIChiLan1.0ChiLan1.0
MRPL20
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21226,817,684 - 226,823,585 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,515,726 - 225,521,152 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01157,984 - 163,411 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111,358,009 - 1,363,012 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11,358,009 - 1,363,014 (-)Ensemblpanpan1.1panPan2
MRPL20
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,553,326 - 56,558,182 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,553,331 - 56,558,136 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,629,506 - 56,634,365 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,755,633 - 56,760,741 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,755,638 - 56,760,692 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,746,132 - 56,750,989 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,638,398 - 56,643,257 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0557,028,682 - 57,033,572 (-)NCBIUU_Cfam_GSD_1.0
Mrpl20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,702,757 - 27,705,717 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049367371,760,236 - 1,761,776 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRPL20
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,670,755 - 63,675,839 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1663,670,750 - 63,675,834 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2658,274,566 - 58,279,667 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MRPL20
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120130,042,502 - 130,047,019 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605434,584,210 - 34,588,291 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrpl20
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248188,228,005 - 8,231,009 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248188,227,947 - 8,231,006 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mrpl20
19 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:98
Count of miRNA genes:86
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000025213
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat

Markers in Region
RH133343  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map4419.82UniSTS
Cytogenetic Map5q36UniSTS
RH135074  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,408,786 - 166,408,980 (+)MAPPERmRatBN7.2
Rnor_6.05173,248,070 - 173,248,263NCBIRnor6.0
Rnor_5.05176,723,684 - 176,723,877UniSTSRnor5.0
RGSC_v3.45172,657,748 - 172,657,941UniSTSRGSC3.4
Celera5164,609,523 - 164,609,716UniSTS
RH 3.4 Map51174.7UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000025213   ⟹   ENSRNOP00000025213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5166,408,962 - 166,413,492 (+)Ensembl
Rnor_6.0 Ensembl5173,248,245 - 173,252,775 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116054   ⟹   ENSRNOP00000085470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5166,409,090 - 166,413,492 (+)Ensembl
RefSeq Acc Id: NM_001109428   ⟹   NP_001102898
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,691,198 - 171,695,728 (+)NCBI
mRatBN7.25166,408,962 - 166,413,492 (+)NCBI
Rnor_6.05173,248,245 - 173,252,775 (+)NCBI
Rnor_5.05176,723,859 - 176,728,389 (+)NCBI
RGSC_v3.45172,657,923 - 172,662,453 (+)RGD
Celera5164,609,698 - 164,614,228 (+)RGD
Sequence:
RefSeq Acc Id: XM_063288394   ⟹   XP_063144464
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,690,664 - 171,695,728 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001102898 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144464 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66541 (Get FASTA)   NCBI Sequence Viewer  
  EDL81326 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025213
  ENSRNOP00000025213.4
  ENSRNOP00000085470.1
RefSeq Acc Id: NP_001102898   ⟸   NM_001109428
- UniProtKB: B2GV62 (UniProtKB/TrEMBL),   A6IUS6 (UniProtKB/TrEMBL),   F7ELM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000025213   ⟸   ENSRNOT00000025213
RefSeq Acc Id: ENSRNOP00000085470   ⟸   ENSRNOT00000116054
RefSeq Acc Id: XP_063144464   ⟸   XM_063288394
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2GV62-F1-model_v2 AlphaFold B2GV62 1-149 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694330
Promoter ID:EPDNEW_R4855
Type:initiation region
Name:Mrpl20_1
Description:mitochondrial ribosomal protein L20
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05173,248,341 - 173,248,401EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1588219 AgrOrtholog
BioCyc Gene G2FUF-38897 BioCyc
Ensembl Genes ENSRNOG00000018647 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025213 ENTREZGENE
  ENSRNOT00000025213.6 UniProtKB/TrEMBL
  ENSRNOT00000116054.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1900.20 UniProtKB/TrEMBL
  6.10.160.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7192827 IMAGE-MGC_LOAD
InterPro Ribosomal_L20 UniProtKB/TrEMBL
  Ribosomal_protein_L20_C-ter UniProtKB/TrEMBL
KEGG Report rno:680747 UniProtKB/TrEMBL
MGC_CLONE MGC:188136 IMAGE-MGC_LOAD
NCBI Gene 680747 ENTREZGENE
PANTHER 39S RIBOSOMAL PROTEIN L20, MITOCHONDRIAL UniProtKB/TrEMBL
  Ribosomal_L20 UniProtKB/TrEMBL
Pfam Ribosomal_L20 UniProtKB/TrEMBL
PhenoGen Mrpl20 PhenoGen
PRINTS RIBOSOMALL20 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018647 RatGTEx
Superfamily-SCOP SSF74731 UniProtKB/TrEMBL
UniProt A0A8I6A063_RAT UniProtKB/TrEMBL
  A6IUS6 ENTREZGENE, UniProtKB/TrEMBL
  B2GV62 ENTREZGENE
  F7ELM1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B2GV62 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-05 Mrpl20  mitochondrial ribosomal protein L20  LOC680747  similar to mitochondrial ribosomal protein L20  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC680747  similar to mitochondrial ribosomal protein L20  LOC687253  similar to mitochondrial ribosomal protein L20  Data merged from RGD:1587725 1643240 APPROVED
2006-11-19 LOC680747  similar to mitochondrial ribosomal protein L20      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC687253  similar to mitochondrial ribosomal protein L20      Symbol and Name status set to provisional 70820 PROVISIONAL