(1->4)-beta-D-glucan multiple interactions ISO RGD:1331936 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of AKR1A1 mRNA CTD PMID:36331819 (S)-nicotine multiple interactions ISO RGD:1331936 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 1,2-dimethylhydrazine multiple interactions ISO RGD:1331936 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of AKR1A1 mRNA] CTD PMID:22206623 1,2-dimethylhydrazine increases expression ISO RGD:1331936 6480464 1, 2-Dimethylhydrazine results in increased expression of AKR1A1 mRNA CTD PMID:22206623 1,2-naphthoquinone increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of 1, 2-naphthoquinone CTD PMID:10510318 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO RGD:1331936 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:1331936 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 13-dihydrodaunorubicin multiple interactions ISO RGD:68486 6480464 [AKR1A1 results in increased metabolism of Daunorubicin] which results in increased chemical synthesis of daunorubicinol CTD PMID:18276838 16-Ketoestrone increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of 16-ketoestrone CTD PMID:10510318 17alpha-ethynylestradiol increases expression ISO RGD:1331936 6480464 Ethinyl Estradiol results in increased expression of AKR1A1 mRNA CTD PMID:17942748 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:68486 6480464 Metribolone results in increased expression of AKR1A1 protein CTD PMID:17152098 1H-pyrazole multiple interactions ISO RGD:1331936 6480464 pyrazole inhibits the reaction [AKR1A1 protein results in increased reduction of muconaldehyde] CTD PMID:16289176 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:68486 6480464 2 more ... CTD PMID:31675489 2,2,2-tetramine multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in increased expression of AKR1A1 protein] CTD PMID:19634143 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1331936 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of AKR1A1 mRNA CTD PMID:16214954 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of AKR1A1 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR1A1 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1331936 6480464 Tetrachlorodibenzodioxin affects the expression of AKR1A1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1331936 6480464 Tetrachlorodibenzodioxin results in increased expression of AKR1A1 mRNA CTD PMID:18796159 2,4,6-trinitrotoluene affects expression EXP 6480464 Trinitrotoluene affects the expression of AKR1A1 mRNA CTD PMID:21346803 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:19954255 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of AKR1A1 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of AKR1A1 mRNA CTD PMID:21346803 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin analog results in decreased expression of AKR1A1 protein, alpha-Chlorohydrin results in decreased expression of AKR1A1 protein CTD PMID:26597043 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:68486 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AKR1A1 mRNA CTD PMID:28628672 3-methylcholanthrene increases expression ISO RGD:68486 6480464 Methylcholanthrene results in increased expression of AKR1A1 mRNA CTD PMID:9973208 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1, 2-dithiol-3-thione results in increased expression of AKR1A1 mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol increases expression ISO RGD:68486 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of AKR1A1 protein CTD PMID:34186270 4-formylbenzoic acid increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of 4-carboxybenzaladehyde CTD PMID:10510318 4-hydroxynon-2-enal increases expression ISO RGD:1331936 6480464 4-hydroxy-2-nonenal results in increased expression of AKR1A1 mRNA CTD PMID:19191707 4-hydroxynon-2-enal increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of 4-hydroxy-2-nonenal CTD PMID:10510318 4-nitrobenzaldehyde increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of 4-nitrobenzaldehyde CTD PMID:10510318 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of AKR1A1 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of AKR1A1 mRNA CTD PMID:19483382 9,10-phenanthroquinone multiple interactions ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of and affects the activity of 9, 10-phenanthrenequinone CTD PMID:21910479 acrolein increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of Acrolein CTD PMID:10510318 acrolein affects reduction EXP 6480464 AKR1A1 protein affects the reduction of Acrolein CTD PMID:12604195 aflatoxin B1 decreases expression ISO RGD:68486 6480464 Aflatoxin B1 results in decreased expression of AKR1A1 mRNA CTD PMID:27153756 aldehydo-D-glucose multiple interactions ISO RGD:1331936 6480464 fidarestat inhibits the reaction [Glucose results in decreased expression of AKR1A1 mRNA] CTD PMID:16805838 aldehydo-D-glucose decreases expression ISO RGD:1331936 6480464 Glucose results in decreased expression of AKR1A1 mRNA CTD PMID:16805838 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of AKR1A1 mRNA CTD PMID:19483382 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of AKR1A1 mRNA CTD PMID:16483693 antirheumatic drug decreases expression ISO RGD:68486 6480464 Antirheumatic Agents results in decreased expression of AKR1A1 mRNA CTD PMID:24449571 arecoline decreases expression ISO RGD:68486 6480464 Arecoline results in decreased expression of AKR1A1 mRNA CTD PMID:17682004 aristolochic acid A increases expression ISO RGD:68486 6480464 aristolochic acid I results in increased expression of AKR1A1 protein CTD PMID:33212167 arsenous acid multiple interactions ISO RGD:68486 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1A1 protein] CTD PMID:26598702 atrazine increases expression ISO RGD:68486 6480464 Atrazine results in increased expression of AKR1A1 mRNA CTD PMID:22378314 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of AKR1A1 mRNA CTD PMID:19483382 benzo[a]pyrene affects methylation ISO RGD:68486 6480464 Benzo(a)pyrene affects the methylation of AKR1A1 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:68486 6480464 Benzo(a)pyrene results in decreased expression of AKR1A1 mRNA CTD PMID:32234424 benzo[a]pyrene diol epoxide I increases expression ISO RGD:68486 6480464 7 more ... CTD PMID:19150397 Benzo[a]pyrene-7,8-diol multiple interactions ISO RGD:68486 6480464 [AKR1A1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 more ... CTD PMID:15720144 more ... Benzo[a]pyrene-7,8-diol decreases response to substance ISO RGD:68486 6480464 AKR1A1 protein results in decreased susceptibility to benzo(a)pyrene 7, 8-dihydrodiol CTD PMID:22053912 benzo[a]pyrene-7,8-dione multiple interactions ISO RGD:68486 6480464 [AKR1A1 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7 more ... CTD PMID:15720144 , PMID:21910479 benzo[a]pyrene-7,8-dione increases expression ISO RGD:68486 6480464 benzo(a)pyrene-7, 8-dione results in increased expression of AKR1A1 mRNA CTD PMID:9973208 benzo[a]pyrene-7,8-dione increases chemical synthesis ISO RGD:68486 6480464 AKR1A1 protein results in increased chemical synthesis of benzo(a)pyrene-7, 8-dione CTD PMID:16411658 benzo[a]pyrene-7,8-dione affects chemical synthesis ISO RGD:68486 6480464 AKR1A1 protein affects the chemical synthesis of benzo(a)pyrene-7, 8-dione CTD PMID:15720144 beta-naphthoflavone increases expression ISO RGD:68486 6480464 beta-Naphthoflavone results in increased expression of AKR1A1 mRNA CTD PMID:9973208 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of AKR1A1 mRNA CTD PMID:25181051 more ... bisphenol A decreases expression ISO RGD:68486 6480464 bisphenol A results in decreased expression of AKR1A1 protein CTD PMID:34186270 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of AKR1A1 gene CTD PMID:28505145 bisphenol F multiple interactions ISO RGD:68486 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AKR1A1 mRNA CTD PMID:28628672 bisphenol F increases expression ISO RGD:68486 6480464 bisphenol F results in increased expression of AKR1A1 protein CTD PMID:34186270 cadmium atom multiple interactions ISO RGD:68486 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR1A1 mRNA CTD PMID:35301059 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of AKR1A1 protein CTD PMID:21699967 cadmium dichloride multiple interactions ISO RGD:68486 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR1A1 mRNA CTD PMID:35301059 cadmium dichloride increases expression ISO RGD:68486 6480464 Cadmium Chloride results in increased expression of AKR1A1 protein CTD PMID:24527689 caffeine multiple interactions ISO RGD:1331936 6480464 [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 capsaicin multiple interactions EXP 6480464 Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of AKR1A1 protein] CTD PMID:20359164 carbamazepine affects expression ISO RGD:68486 6480464 Carbamazepine affects the expression of AKR1A1 mRNA CTD PMID:25979313 chenodeoxycholic acid multiple interactions ISO RGD:68486 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR1A1 mRNA CTD PMID:32152650 chlorpyrifos increases expression ISO RGD:1331936 6480464 Chlorpyrifos results in increased expression of AKR1A1 mRNA CTD PMID:37019170 cisplatin multiple interactions ISO RGD:68486 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of AKR1A1 mRNA CTD PMID:27392435 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of AKR1A1 mRNA CTD PMID:19483382 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of AKR1A1 mRNA CTD PMID:17602206 cobalt dichloride decreases expression ISO RGD:68486 6480464 cobaltous chloride results in decreased expression of AKR1A1 mRNA CTD PMID:19376846 copper atom decreases expression EXP 6480464 Copper results in decreased expression of AKR1A1 mRNA CTD PMID:22465980 copper atom affects binding ISO RGD:68486 6480464 AKR1A1 protein binds to Copper CTD PMID:15359738 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of AKR1A1 mRNA CTD PMID:22465980 copper(0) affects binding ISO RGD:68486 6480464 AKR1A1 protein binds to Copper CTD PMID:15359738 copper(II) chloride increases expression ISO RGD:1331936 6480464 cupric chloride results in increased expression of AKR1A1 protein CTD PMID:29617964 copper(II) sulfate decreases expression ISO RGD:68486 6480464 Copper Sulfate results in decreased expression of AKR1A1 mRNA CTD PMID:19549813 crotonaldehyde affects reduction EXP 6480464 AKR1A1 protein affects the reduction of 2-butenal CTD PMID:12604195 cyclosporin A multiple interactions ISO RGD:68486 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR1A1 mRNA CTD PMID:32152650 D-glucose multiple interactions ISO RGD:1331936 6480464 fidarestat inhibits the reaction [Glucose results in decreased expression of AKR1A1 mRNA] CTD PMID:16805838 D-glucose decreases expression ISO RGD:1331936 6480464 Glucose results in decreased expression of AKR1A1 mRNA CTD PMID:16805838 daunorubicin increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of Daunorubicin CTD PMID:18322072 daunorubicin affects metabolic processing ISO RGD:68486 6480464 AKR1A1 SNP affects the metabolism of Daunorubicin CTD PMID:18276838 daunorubicin multiple interactions ISO RGD:68486 6480464 [AKR1A1 results in increased metabolism of Daunorubicin] which results in increased chemical synthesis of daunorubicinol CTD PMID:18276838 daunorubicin increases metabolic processing ISO RGD:68486 6480464 AKR1A1 results in increased metabolism of Daunorubicin CTD PMID:18276838 deoxycholic acid multiple interactions ISO RGD:68486 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR1A1 mRNA CTD PMID:32152650 dexamethasone multiple interactions ISO RGD:68486 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AKR1A1 mRNA CTD PMID:28628672 Diallyl sulfide affects expression EXP 6480464 allyl sulfide affects the expression of AKR1A1 mRNA CTD PMID:19768707 diarsenic trioxide multiple interactions ISO RGD:68486 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1A1 protein] CTD PMID:26598702 dichlorine increases expression EXP 6480464 Chlorine results in increased expression of AKR1A1 mRNA CTD PMID:18636392 dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of AKR1A1 mRNA CTD PMID:18636392 diethyl maleate increases expression EXP 6480464 diethyl maleate results in increased expression of AKR1A1 protein CTD PMID:21161181 diuron decreases expression ISO RGD:68486 6480464 Diuron results in decreased expression of AKR1A1 mRNA CTD PMID:35967413 doxorubicin increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of Doxorubicin CTD PMID:18322072 doxorubicin affects metabolic processing ISO RGD:68486 6480464 AKR1A1 SNP affects the metabolism of Doxorubicin CTD PMID:18276838 doxorubicin multiple interactions ISO RGD:68486 6480464 [AKR1A1 results in increased metabolism of Doxorubicin] which results in increased chemical synthesis of adriamycinol CTD PMID:18276838 doxorubicin increases metabolic processing ISO RGD:68486 6480464 AKR1A1 results in increased metabolism of Doxorubicin CTD PMID:18276838 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of AKR1A1 mRNA CTD PMID:29391264 enzyme inhibitor multiple interactions ISO RGD:68486 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of AKR1A1 protein CTD PMID:23301498 ethanol affects splicing ISO RGD:1331936 6480464 Ethanol affects the splicing of AKR1A1 mRNA CTD PMID:30319688 Fidarestat multiple interactions ISO RGD:1331936 6480464 fidarestat inhibits the reaction [Glucose results in decreased expression of AKR1A1 mRNA] CTD PMID:16805838 flutamide increases expression EXP 6480464 Flutamide results in increased expression of AKR1A1 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:1331936 6480464 Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in increased expression of AKR1A1 mRNA] CTD PMID:22206623 fumonisin B1 increases expression ISO RGD:1331936 6480464 fumonisin B1 results in increased expression of AKR1A1 mRNA CTD PMID:16221962 furan increases expression EXP 6480464 furan results in increased expression of AKR1A1 mRNA CTD PMID:25539665 , PMID:26194646 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of AKR1A1 mRNA CTD PMID:22061828 glafenine increases expression EXP 6480464 Glafenine results in increased expression of AKR1A1 mRNA CTD PMID:24136188 glucose multiple interactions ISO RGD:1331936 6480464 fidarestat inhibits the reaction [Glucose results in decreased expression of AKR1A1 mRNA] CTD PMID:16805838 glucose decreases expression ISO RGD:1331936 6480464 Glucose results in decreased expression of AKR1A1 mRNA CTD PMID:16805838 glucuronic acid increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of Glucuronic Acid CTD PMID:10510318 glucuronic acid increases reduction EXP 6480464 AKR1A1 protein results in increased reduction of Glucuronic Acid CTD PMID:29763686 glycidyl methacrylate decreases expression ISO RGD:68486 6480464 glycidyl methacrylate results in decreased expression of AKR1A1 protein CTD PMID:36641056 glycochenodeoxycholic acid multiple interactions ISO RGD:68486 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR1A1 mRNA CTD PMID:32152650 glycocholic acid multiple interactions ISO RGD:68486 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR1A1 mRNA CTD PMID:32152650 glycodeoxycholic acid multiple interactions ISO RGD:68486 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR1A1 mRNA CTD PMID:32152650 hexane-2,3-dione increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of 2, 3-hexanedione CTD PMID:10510318 hydralazine multiple interactions ISO RGD:68486 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of AKR1A1 mRNA CTD PMID:17183730 hypochlorous acid increases expression ISO RGD:1331936 6480464 Hypochlorous Acid results in increased expression of AKR1A1 mRNA CTD PMID:19376150 indometacin multiple interactions ISO RGD:68486 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AKR1A1 mRNA CTD PMID:28628672 indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of AKR1A1 mRNA CTD PMID:36868495 inulin multiple interactions ISO RGD:1331936 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of AKR1A1 mRNA CTD PMID:36331819 isotretinoin decreases expression ISO RGD:68486 6480464 Isotretinoin results in decreased expression of AKR1A1 mRNA CTD PMID:20436886 ivermectin decreases expression ISO RGD:68486 6480464 Ivermectin results in decreased expression of AKR1A1 protein CTD PMID:32959892 L-ascorbic acid decreases abundance ISO RGD:1331936 6480464 AKR1A1 gene mutant form results in decreased abundance of Ascorbic Acid CTD PMID:32805337 L-ascorbic acid multiple interactions ISO RGD:1331936 6480464 [AKR1A1 gene mutant form results in increased susceptibility to Diethylnitrosamine] which results in decreased abundance of Ascorbic Acid, AKR1A1 gene mutant form promotes the reaction [Diethylnitrosamine results in decreased abundance of Ascorbic Acid] CTD PMID:32805337 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of AKR1A1 mRNA CTD PMID:19483382 methidathion increases expression ISO RGD:1331936 6480464 methidathion results in increased expression of AKR1A1 mRNA CTD PMID:34813904 methylglyoxal increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of Pyruvaldehyde CTD PMID:10510318 methylglyoxal increases reduction EXP 6480464 AKR1A1 protein results in increased reduction of Pyruvaldehyde CTD PMID:29763686 monosodium L-glutamate increases expression ISO RGD:1331936 6480464 Sodium Glutamate results in increased expression of AKR1A1 mRNA, Sodium Glutamate results in increased expression of AKR1A1 protein CTD PMID:25473020 Muconic dialdehyde increases reduction ISO RGD:1331936 6480464 AKR1A1 protein results in increased reduction of muconaldehyde CTD PMID:16289176 Muconic dialdehyde multiple interactions ISO RGD:1331936 6480464 pyrazole inhibits the reaction [AKR1A1 protein results in increased reduction of muconaldehyde] CTD PMID:16289176 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of AKR1A1 mRNA CTD PMID:17602206 N-nitrosodiethylamine increases response to substance ISO RGD:1331936 6480464 AKR1A1 gene mutant form results in increased susceptibility to Diethylnitrosamine CTD PMID:32805337 N-nitrosodiethylamine multiple interactions ISO RGD:1331936 6480464 [AKR1A1 gene mutant form results in increased susceptibility to Diethylnitrosamine] which results in decreased abundance of Ascorbic Acid, AKR1A1 gene mutant form promotes the reaction [Diethylnitrosamine results in decreased abundance of Ascorbic Acid] CTD PMID:32805337 NAD zwitterion multiple interactions ISO RGD:68486 6480464 NAD promotes the reaction [AKR1A1 protein affects the chemical synthesis of benzo(a)pyrene-7 more ... CTD PMID:15720144 NAD(+) multiple interactions ISO RGD:68486 6480464 NAD promotes the reaction [AKR1A1 protein affects the chemical synthesis of benzo(a)pyrene-7 more ... CTD PMID:15720144 NADP zwitterion multiple interactions ISO RGD:68486 6480464 [AKR1A1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 more ... CTD PMID:15720144 , PMID:21910479 NADP(+) multiple interactions ISO RGD:68486 6480464 [AKR1A1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 more ... CTD PMID:15720144 , PMID:21910479 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of AKR1A1 mRNA CTD PMID:24136188 nicotine multiple interactions ISO RGD:1331936 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of AKR1A1 mRNA CTD PMID:24136188 ochratoxin A decreases expression ISO RGD:68486 6480464 ochratoxin A results in decreased expression of AKR1A1 mRNA CTD PMID:32905824 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of AKR1A1 mRNA CTD PMID:19483382 ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of AKR1A1 mRNA CTD PMID:18636392 pentachlorophenol increases expression ISO RGD:1331936 6480464 Pentachlorophenol results in increased expression of AKR1A1 mRNA CTD PMID:23892564 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:1331936 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of AKR1A1 mRNA more ... CTD PMID:36331819 perfluorooctanoic acid affects expression ISO RGD:1331936 6480464 perfluorooctanoic acid affects the expression of AKR1A1 mRNA CTD PMID:18281256 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of AKR1A1 mRNA CTD PMID:19768707 phenobarbital affects expression ISO RGD:68486 6480464 Phenobarbital affects the expression of AKR1A1 mRNA CTD PMID:19159669 Phenylglyoxal increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of Phenylglyoxal CTD PMID:10510318 phlorizin decreases expression ISO RGD:1331936 6480464 Phlorhizin results in decreased expression of AKR1A1 mRNA CTD PMID:22538082 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of AKR1A1 mRNA CTD PMID:19483382 pyrogallol increases expression ISO RGD:1331936 6480464 Pyrogallol results in increased expression of AKR1A1 mRNA CTD PMID:20362636 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of AKR1A1 mRNA CTD PMID:19072884 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of AKR1A1 protein CTD PMID:29459688 sodium dichromate increases expression ISO RGD:1331936 6480464 sodium bichromate results in increased expression of AKR1A1 mRNA CTD PMID:22155349 sodium dichromate decreases expression ISO RGD:68486 6480464 sodium bichromate results in decreased expression of AKR1A1 mRNA CTD PMID:17685462 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of AKR1A1 mRNA CTD PMID:22561333 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of AKR1A1 protein CTD PMID:19634143 streptozocin multiple interactions EXP 6480464 Trientine inhibits the reaction [Streptozocin results in increased expression of AKR1A1 protein] CTD PMID:19634143 succinic semialdehyde increases reduction ISO RGD:68486 6480464 AKR1A1 protein results in increased reduction of succinic semialdehyde CTD PMID:10510318 , PMID:21276435 tetrachloroethene decreases expression ISO RGD:1331936 6480464 Tetrachloroethylene results in decreased expression of AKR1A1 mRNA CTD PMID:28973375 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of AKR1A1 mRNA CTD PMID:19483382 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of AKR1A1 mRNA CTD PMID:34492290 thioacetamide multiple interactions ISO RGD:1331936 6480464 AKR1A1 protein affects the reaction [Thioacetamide results in increased activity of GPT protein], AKR1A1 protein affects the reaction [Thioacetamide results in increased expression of DDIT3 protein] CTD PMID:29763686 thioacetamide increases response to substance ISO RGD:1331936 6480464 AKR1A1 protein results in increased susceptibility to Thioacetamide CTD PMID:29763686 urethane decreases expression ISO RGD:68486 6480464 Urethane results in decreased expression of AKR1A1 mRNA CTD PMID:28818685 valproic acid multiple interactions ISO RGD:68486 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of AKR1A1 mRNA CTD PMID:17183730 valproic acid affects expression ISO RGD:68486 6480464 Valproic Acid affects the expression of AKR1A1 mRNA CTD PMID:25979313 valproic acid affects expression ISO RGD:1331936 6480464 Valproic Acid affects the expression of AKR1A1 mRNA CTD PMID:17292431 Yessotoxin increases expression ISO RGD:68486 6480464 yessotoxin analog results in increased expression of AKR1A1 mRNA CTD PMID:30679557 zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of AKR1A1 mRNA CTD PMID:11717422 zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of AKR1A1 mRNA CTD PMID:11717422 zoledronic acid increases expression ISO RGD:68486 6480464 zoledronic acid results in increased expression of AKR1A1 mRNA CTD PMID:24714768