Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ppih | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Ppih (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of PPIH mRNA | CTD | PMID:17555576 | Ppih | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Ppih (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPIH mRNA | CTD | PMID:17942748 | Ppih | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Ppih (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of PPIH mRNA | CTD | PMID:17942748 | Ppih | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Ppih | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ppih (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPIH mRNA | CTD | PMID:17942748 | Ppih | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ppih (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PPIH mRNA | CTD | PMID:21570461 | Ppih | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ppih (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PPIH mRNA | CTD | PMID:25270620 | Ppih | Rat | 2,3-dimethoxynaphthalene-1,4-dione | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:17547211 | Ppih | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Ppih (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of PPIH mRNA | CTD | PMID:20188158 | Ppih | Rat | 3-methylcholanthrene | increases expression | ISO | Ppih (Mus musculus) | 6480464 | Methylcholanthrene results in increased expression of PPIH mRNA | CTD | PMID:20713471 | Ppih | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Ppih (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of PPIH mRNA | CTD | PMID:18648102 | Ppih | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of PPIH mRNA | CTD | PMID:36041667 | Ppih | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Ppih (Mus musculus) | 6480464 | Fenretinide results in decreased expression of PPIH mRNA | CTD | PMID:28973697 | Ppih | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of PPIH mRNA | CTD | PMID:24780913 | Ppih | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PPIH mRNA | CTD | PMID:35163327 | Ppih | Rat | antimony(0) | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | Antimony results in increased expression of PPIH mRNA | CTD | PMID:17547211 | Ppih | Rat | arsenous acid | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PPIH mRNA | CTD | PMID:17547211 | Ppih | Rat | benzo[a]pyrene | decreases methylation | ISO | PPIH (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PPIH promoter | CTD | PMID:27901495 | Ppih | Rat | beta-lapachone | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of PPIH mRNA | CTD | PMID:38218311 | Ppih | Rat | bis(2-chloroethyl) sulfide | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | Mustard Gas results in decreased expression of PPIH mRNA | CTD | PMID:25102026 | Ppih | Rat | bisphenol A | increases expression | ISO | Ppih (Mus musculus) | 6480464 | bisphenol A results in increased expression of PPIH mRNA | CTD | PMID:25594700 | Ppih | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of PPIH mRNA | CTD | PMID:36041667 | Ppih | Rat | bisphenol A | affects expression | ISO | PPIH (Homo sapiens) | 6480464 | bisphenol A affects the expression of PPIH mRNA | CTD | PMID:30903817 | Ppih | Rat | bisphenol A | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PPIH mRNA and bisphenol A results in decreased expression of PPIH protein | CTD | PMID:29275510 and PMID:31675489 | Ppih | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of PPIH mRNA | CTD | PMID:36041667 | Ppih | Rat | cadmium dichloride | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of PPIH mRNA | CTD | PMID:38382870 | Ppih | Rat | calcitriol | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of PPIH mRNA | CTD | PMID:21592394 | Ppih | Rat | calcitriol | multiple interactions | ISO | PPIH (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of PPIH mRNA | CTD | PMID:21592394 | Ppih | Rat | carbon nanotube | increases expression | ISO | Ppih (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Ppih | Rat | CGP 52608 | multiple interactions | ISO | PPIH (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PPIH gene] | CTD | PMID:28238834 | Ppih | Rat | chlorpyrifos | decreases expression | ISO | Ppih (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of PPIH mRNA | CTD | PMID:37019170 | Ppih | Rat | chromium atom | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | Chromium results in increased expression of PPIH mRNA | CTD | PMID:17547211 | Ppih | Rat | clofibrate | decreases expression | ISO | Ppih (Mus musculus) | 6480464 | Clofibrate results in decreased expression of PPIH mRNA | CTD | PMID:25270620 | Ppih | Rat | cobalt dichloride | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of PPIH mRNA | CTD | PMID:19376846 | Ppih | Rat | cyclosporin A | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PPIH mRNA | CTD | PMID:25562108 | Ppih | Rat | decabromodiphenyl ether | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of PPIH protein | CTD | PMID:31675489 | Ppih | Rat | dextran sulfate | decreases expression | ISO | Ppih (Mus musculus) | 6480464 | Dextran Sulfate results in decreased expression of PPIH protein | CTD | PMID:32272095 | Ppih | Rat | dextran sulfate | increases expression | ISO | Ppih (Mus musculus) | 6480464 | Dextran Sulfate results in increased expression of PPIH protein | CTD | PMID:35362542 | Ppih | Rat | dextran sulfate | multiple interactions | ISO | Ppih (Mus musculus) | 6480464 | Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PPIH protein] and evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PPIH protein] | CTD | PMID:32272095 and PMID:35362542 | Ppih | Rat | diarsenic trioxide | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PPIH mRNA | CTD | PMID:17547211 | Ppih | Rat | dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | Antimony Potassium Tartrate results in increased expression of PPIH mRNA | CTD | PMID:17547211 | Ppih | Rat | doxorubicin | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PPIH mRNA | CTD | PMID:29803840 | Ppih | Rat | Evodiamine | multiple interactions | ISO | Ppih (Mus musculus) | 6480464 | evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PPIH protein] | CTD | PMID:35362542 | Ppih | Rat | ivermectin | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PPIH protein | CTD | PMID:32959892 | Ppih | Rat | mercury atom | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | Mercury results in increased expression of PPIH mRNA | CTD | PMID:17547211 | Ppih | Rat | mercury(0) | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | Mercury results in increased expression of PPIH mRNA | CTD | PMID:17547211 | Ppih | Rat | methamphetamine | decreases methylation | ISO | Ppih (Mus musculus) | 6480464 | Methamphetamine results in decreased methylation of PPIH promoter | CTD | PMID:26307267 | Ppih | Rat | methotrexate | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | Methotrexate results in decreased expression of PPIH mRNA | CTD | PMID:24449571 | Ppih | Rat | methyl methanesulfonate | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of PPIH mRNA | CTD | PMID:23649840 | Ppih | Rat | ozone | multiple interactions | ISO | Ppih (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of PPIH mRNA | CTD | PMID:34911549 | Ppih | Rat | paracetamol | affects expression | ISO | Ppih (Mus musculus) | 6480464 | Acetaminophen affects the expression of PPIH mRNA | CTD | PMID:17562736 | Ppih | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PPIH mRNA | CTD | PMID:35163327 | Ppih | Rat | phenethyl isothiocyanate | decreases expression | EXP | | 6480464 | phenethyl isothiocyanate results in decreased expression of PPIH mRNA | CTD | PMID:17616710 | Ppih | Rat | phenobarbital | decreases expression | ISO | Ppih (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of PPIH mRNA | CTD | PMID:25270620 | Ppih | Rat | pirinixic acid | multiple interactions | ISO | Ppih (Mus musculus) | 6480464 | PPARA protein affects the reaction [pirinixic acid results in increased expression of PPIH mRNA] | CTD | PMID:21318169 | Ppih | Rat | pirinixic acid | increases expression | ISO | Ppih (Mus musculus) | 6480464 | pirinixic acid results in increased expression of PPIH mRNA | CTD | PMID:18301758 and PMID:21318169 | Ppih | Rat | potassium dichromate | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | Potassium Dichromate results in increased expression of PPIH mRNA | CTD | PMID:17547211 | Ppih | Rat | sodium arsenite | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PPIH mRNA | CTD | PMID:28595984 and PMID:34032870 | Ppih | Rat | sodium arsenite | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PPIH mRNA | CTD | PMID:38568856 | Ppih | Rat | sunitinib | increases expression | ISO | PPIH (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PPIH mRNA | CTD | PMID:31533062 | Ppih | Rat | tamoxifen | affects expression | ISO | Ppih (Mus musculus) | 6480464 | Tamoxifen affects the expression of PPIH mRNA | CTD | PMID:17555576 | Ppih | Rat | testosterone | multiple interactions | ISO | PPIH (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of PPIH mRNA | CTD | PMID:21592394 | Ppih | Rat | testosterone | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | Testosterone results in decreased expression of PPIH mRNA | CTD | PMID:21592394 | Ppih | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of PPIH mRNA | CTD | PMID:33387578 | Ppih | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PPIH mRNA | CTD | PMID:34492290 | Ppih | Rat | titanium dioxide | decreases methylation | ISO | Ppih (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of PPIH promoter | CTD | PMID:35295148 | Ppih | Rat | Tributyltin oxide | decreases expression | ISO | Ppih (Mus musculus) | 6480464 | bis(tri-n-butyltin)oxide results in decreased expression of PPIH mRNA | CTD | PMID:25270620 | Ppih | Rat | trimellitic anhydride | increases expression | ISO | Ppih (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of PPIH mRNA | CTD | PMID:19042947 | Ppih | Rat | triptonide | increases expression | ISO | Ppih (Mus musculus) | 6480464 | triptonide results in increased expression of PPIH mRNA | CTD | PMID:33045310 | Ppih | Rat | troglitazone | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | troglitazone results in decreased expression of PPIH mRNA | CTD | PMID:19140230 | Ppih | Rat | valproic acid | increases methylation | ISO | PPIH (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of PPIH gene | CTD | PMID:29154799 | Ppih | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of PPIH mRNA | CTD | PMID:23555832 | Ppih | Rat | Yessotoxin | decreases expression | ISO | PPIH (Homo sapiens) | 6480464 | yessotoxin analog results in decreased expression of PPIH mRNA | CTD | PMID:30679557 | |