PPIH (peptidylprolyl isomerase H) - Rat Genome Database

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Gene: PPIH (peptidylprolyl isomerase H) Chlorocebus sabaeus
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Symbol: PPIH
Name: peptidylprolyl isomerase H
RGD ID: 18391190
Description: ENCODES a protein that exhibits ribonucleoprotein complex binding (ortholog); INVOLVED IN positive regulation of viral genome replication (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); nuclear speck (ortholog); U4/U6 snRNP (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peptidyl-prolyl cis-trans isomerase H
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12090,250,959 - 90,275,275 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2090,256,081 - 90,274,751 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603326,635,055 - 26,659,466 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PPIH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12090,250,959 - 90,275,275 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2090,256,081 - 90,274,751 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603326,635,055 - 26,659,466 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PPIH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38142,658,423 - 42,681,654 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl142,658,335 - 42,676,758 (+)EnsemblGRCh38hg38GRCh38
GRCh37143,124,094 - 43,142,429 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36142,896,635 - 42,915,016 (+)NCBINCBI36Build 36hg18NCBI36
Build 34142,793,140 - 42,811,521NCBI
Celera141,405,975 - 41,424,356 (+)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef141,244,218 - 41,262,600 (+)NCBIHuRef
CHM1_1143,240,906 - 43,259,287 (+)NCBICHM1_1
T2T-CHM13v2.0142,528,918 - 42,552,149 (+)NCBIT2T-CHM13v2.0
Ppih
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394119,157,207 - 119,177,720 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4119,157,207 - 119,177,743 (-)EnsemblGRCm39 Ensembl
GRCm384119,300,010 - 119,320,523 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4119,300,010 - 119,320,546 (-)EnsemblGRCm38mm10GRCm38
MGSCv374118,972,615 - 118,993,128 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364118,797,947 - 118,818,411 (-)NCBIMGSCv36mm8
Celera4118,027,842 - 118,048,366 (-)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map455.34NCBI
Ppih
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85138,191,624 - 138,209,625 (-)NCBIGRCr8
mRatBN7.25132,906,324 - 132,924,341 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5132,906,328 - 132,924,267 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5135,633,875 - 135,652,694 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05137,390,334 - 137,409,153 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05137,410,930 - 137,429,749 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05138,343,934 - 138,361,743 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5138,352,916 - 138,361,702 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05142,160,007 - 142,178,024 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45139,959,365 - 139,969,320 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5131,431,800 - 131,449,612 (-)NCBICelera
Cytogenetic Map5q36NCBI
Ppih
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555372,211,410 - 2,230,452 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555372,211,566 - 2,229,444 (+)NCBIChiLan1.0ChiLan1.0
PPIH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21184,130,421 - 184,153,502 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11183,272,085 - 183,295,157 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,958,260 - 41,981,598 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1143,336,039 - 43,354,609 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl143,336,039 - 43,353,898 (+)Ensemblpanpan1.1panPan2
PPIH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.115671,323 - 689,627 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl15671,324 - 689,544 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha15926,045 - 944,371 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.015752,681 - 771,039 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl15752,682 - 770,962 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.115662,128 - 680,381 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.015723,569 - 741,836 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.015738,714 - 757,011 (-)NCBIUU_Cfam_GSD_1.0
Ppih
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505858,179,131 - 58,200,103 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647424,003,827 - 24,024,922 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647424,003,963 - 24,024,885 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPIH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6168,742,005 - 168,760,286 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16168,741,999 - 168,760,350 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26156,223,015 - 156,241,360 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ppih
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248921,916,912 - 1,935,875 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248921,916,873 - 1,935,458 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 35 9 39
Low 1 11 21
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000017366   ⟹   ENSCSAP00000016847
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2090,256,081 - 90,274,751 (-)Ensembl
RefSeq Acc Id: XM_007979150   ⟹   XP_007977341
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12090,256,417 - 90,275,273 (-)NCBI
Vero_WHO_p1.0NW_02366603326,635,055 - 26,654,001 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007979151   ⟹   XP_007977342
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12090,257,275 - 90,275,275 (-)NCBI
Vero_WHO_p1.0NW_02366603326,635,055 - 26,653,261 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007979152   ⟹   XP_007977343
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12090,257,275 - 90,275,275 (-)NCBI
Vero_WHO_p1.0NW_02366603326,635,055 - 26,653,261 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007979153   ⟹   XP_007977344
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12090,250,959 - 90,275,275 (-)NCBI
Vero_WHO_p1.0NW_02366603326,635,055 - 26,659,466 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007977341 (Get FASTA)   NCBI Sequence Viewer  
  XP_007977342 (Get FASTA)   NCBI Sequence Viewer  
  XP_007977343 (Get FASTA)   NCBI Sequence Viewer  
  XP_007977344 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000016847
  ENSCSAP00000016847.1
RefSeq Acc Id: XP_007977344   ⟸   XM_007979153
- UniProtKB: A0A0D9S7K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007977341   ⟸   XM_007979150
- UniProtKB: A0A0D9S7K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007977343   ⟸   XM_007979152
- UniProtKB: A0A0D9S7K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007977342   ⟸   XM_007979151
- UniProtKB: A0A0D9S7K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000016847   ⟸   ENSCSAT00000017366


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000001167 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000017366.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.100.10 UniProtKB/TrEMBL
InterPro Cyclophilin-like_dom_sf UniProtKB/TrEMBL
  Cyclophilin-type_PPIase UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_CS UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_dom UniProtKB/TrEMBL
KEGG Report csab:103225001 UniProtKB/TrEMBL
NCBI Gene PPIH ENTREZGENE
PANTHER PEPTIDYL-PROLYL CIS-TRANS ISOMERASE UniProtKB/TrEMBL
  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED UniProtKB/TrEMBL
Pfam Pro_isomerase UniProtKB/TrEMBL
PIRSF Peptidylpro_ismrse UniProtKB/TrEMBL
PRINTS CSAPPISMRASE UniProtKB/TrEMBL
PROSITE CSA_PPIASE_1 UniProtKB/TrEMBL
  CSA_PPIASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50891 UniProtKB/TrEMBL
UniProt A0A0D9S7K8 ENTREZGENE, UniProtKB/TrEMBL