Ldlrap1 (low density lipoprotein receptor adaptor protein 1) - Rat Genome Database

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Gene: Ldlrap1 (low density lipoprotein receptor adaptor protein 1) Heterocephalus glaber
Analyze
Symbol: Ldlrap1
Name: low density lipoprotein receptor adaptor protein 1
RGD ID: 18924400
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); AP-1 adaptor complex binding (ortholog); AP-2 adaptor complex binding (ortholog); INVOLVED IN amyloid precursor protein metabolic process (ortholog); cellular response to cytokine stimulus (ortholog); cholesterol homeostasis (ortholog); ASSOCIATED WITH autosomal recessive hypercholesterolemia (ortholog); familial hypercholesterolemia (ortholog); genetic disease (ortholog); FOUND IN axon (ortholog); basal plasma membrane (ortholog); cytoplasmic side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Low density lipoprotein receptor adapter protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247649,675,845 - 9,699,597 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247649,675,917 - 9,699,597 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Ldlrap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247649,675,845 - 9,699,597 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247649,675,917 - 9,699,597 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LDLRAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38125,543,606 - 25,590,400 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl125,543,606 - 25,568,886 (+)EnsemblGRCh38hg38GRCh38
GRCh37125,870,097 - 25,895,377 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36125,742,663 - 25,767,964 (+)NCBINCBI36Build 36hg18NCBI36
Celera124,265,963 - 24,291,423 (+)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef124,124,497 - 24,149,801 (+)NCBIHuRef
CHM1_1125,983,497 - 26,008,795 (+)NCBICHM1_1
T2T-CHM13v2.0125,380,944 - 25,427,735 (+)NCBIT2T-CHM13v2.0
Ldlrap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394134,468,865 - 134,495,342 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4134,468,865 - 134,495,335 (-)EnsemblGRCm39 Ensembl
GRCm384134,741,554 - 134,768,032 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,741,554 - 134,768,024 (-)EnsemblGRCm38mm10GRCm38
MGSCv374134,301,327 - 134,323,919 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364134,017,498 - 134,040,023 (-)NCBIMGSCv36mm8
Celera4132,929,656 - 132,952,236 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map467.09NCBI
Ldlrap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85152,239,296 - 152,262,290 (-)NCBIGRCr8
mRatBN7.25146,955,607 - 146,978,601 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,955,607 - 146,978,601 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5149,656,442 - 149,679,565 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05151,427,752 - 151,450,746 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05151,412,689 - 151,435,812 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,964,294 - 152,987,286 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,966,591 - 152,987,211 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05156,742,863 - 156,765,855 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45153,504,535 - 153,527,523 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5145,368,945 - 145,391,939 (-)NCBICelera
Cytogenetic Map5q36NCBI
Ldlrap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,081,556 - 5,095,182 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,081,919 - 5,102,349 (+)NCBIChiLan1.0ChiLan1.0
LDLRAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21201,263,219 - 201,336,642 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11200,376,406 - 200,434,513 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0124,809,535 - 24,852,394 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1125,871,874 - 25,920,550 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl125,878,358 - 25,903,336 (+)Ensemblpanpan1.1panPan2
LDLRAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,340,272 - 74,363,929 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,341,036 - 74,364,162 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,914,328 - 70,937,998 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,901,453 - 74,925,396 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,901,458 - 74,925,371 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,724,767 - 71,748,432 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,731,525 - 72,755,221 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,735,844 - 73,759,564 (-)NCBIUU_Cfam_GSD_1.0
Ldlrap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505844,371,440 - 44,395,584 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647410,196,211 - 10,221,777 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647410,196,228 - 10,219,137 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LDLRAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,030,702 - 83,054,377 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,030,629 - 83,054,387 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2676,601,373 - 76,625,132 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LDLRAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120107,207,363 - 107,232,237 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20107,207,334 - 107,229,210 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660339,131,295 - 9,155,884 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000017187   ⟹   ENSHGLP00000017016
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247649,675,845 - 9,699,597 (+)Ensembl
RefSeq Acc Id: XM_004850611   ⟹   XP_004850668
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247649,675,917 - 9,699,597 (+)NCBI
RefSeq Acc Id: XM_004850612   ⟹   XP_004850669
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247649,675,917 - 9,699,597 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004850668 (Get FASTA)   NCBI Sequence Viewer  
  XP_004850669 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB08873 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017016
GenBank Protein JAO01200 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004850668   ⟸   XM_004850611
- Peptide Label: isoform X1
- UniProtKB: G5BHW2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004850669   ⟸   XM_004850612
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000017016   ⟸   ENSHGLT00000017187


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012177 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000017187 ENTREZGENE
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/TrEMBL
KEGG Report hgl:101699111 UniProtKB/TrEMBL
NCBI Gene Ldlrap1 ENTREZGENE
PANTHER LOW DENSITY LIPOPROTEIN RECEPTOR ADAPTER PROTEIN 1 UniProtKB/TrEMBL
  PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER UniProtKB/TrEMBL
Pfam PID UniProtKB/TrEMBL
PROSITE PID UniProtKB/TrEMBL
SMART PTB UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt G5BHW2 ENTREZGENE, UniProtKB/TrEMBL