Strain Report - Rat Genome Database

Name: LE- Scn2a em1Mcwi
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: LE-Scn2a^em1Mcwi

Symbol:

LE-Scn2a^em1Mcwi

Strain:

LE-Scn2a^em1

Substrain:

Mcwi

RGD ID:

25394530

Citation ID:

RRID:RGD_25394530

Ontology ID:

RS:0004785

Alleles:

Scn2a^em1Mcwi

Type:

mutant

Source:

MCW Gene Editing Rat Resource Center

Origin:

The rat strain was produced by injecting CRISPR/Cas9 targeting rat Scn2a into Crl:LE embryos. The mutant allele was produced by injecting CRISPR/Cas9 targeting rat Scn2a into Crl:LE embryos. The resulting mutation is net 4-bp deletion in exon 5 comprising a 10-bp deletion (shown in lower case: CTACGGGATccctggaattGGTTGGATTTCACAGTCATT ) and a 6-bp insertion (TTCACT).

Last Known Status:

Live Animals (as of 2021-11-03)

Genotyping Protocol

Download Genotyping Protocol

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	50,302,781 - 50,437,504	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	3	51,687,910 - 51,822,008	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	3	58,322,640 - 58,456,658	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	3	47,588,413 - 47,722,800	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

References

Region

Additional Information

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: LE-Scn2aem1Mcwi

Strain: LE-Scn2a^em1Mcwi