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Strain Registration

Strain: T2DN-Sirt3em35Mcwi

Symbol: T2DN-Sirt3em35Mcwi
Strain: T2DN-Sirt3em35
Substrain: Mcwi
RGD ID: 10054456
Citation ID: RRID:RGD_10054456
Ontology ID: RS:0004015
Alleles: Sirt3em35Mcwi
Also Known As: Strain00289; T2DN-Sirt3em35Mcwi; T2DN-Sirt3^[em35Mcwi]
Type: mutant
Available Source: Contact MCW rat distribution at mcwcustomrats@mcw.edu
Origination: MCW Gene Editing Rat Resource Center
Description: CRISPR/Cas9 system was used to introduce a mutation in the Sirt3 gene of T2DN/Mcwi rat embryos. The resulting mutation is a 82-bp deletion of exon 3 in the Sirt3 gene.
Last Known Status: Cryopreserved Sperm (as of 2018-10-22)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21195,955,280 - 195,955,361RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01213,613,502 - 213,636,061RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01220,539,132 - 220,561,380RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41201,021,391 - 201,043,756RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Data registered by Dr. Melinda Dwinell’s group Personal communication between Dr. Melinda Dwinell’s group and the RGD curators

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Sirt3em35Mcwi-var1 chr1 195955280 195955361 GTGTGTAGAGCCGCAGAAGCAGCTCCTTGTCGTGAAGCAGCCGAAGGAAGTAGTGAGCGACATTGGGCCTGTAGTGCCCAGG - deletion mRatBN7.2

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-05 T2DN-Sirt3em35Mcwi    T2DN-Sirt3em25Mcwi    Symbol updated 68687 APPROVED
2016-10-05 T2DN-Sirt3em35Mcwi    T2DN-Sirt3em25Mcwi    Symbol updated 68687 APPROVED
2016-03-16 T2DN-Sirt3em25Mcwi    T2DN-Sirt3em25Mcwi    Symbol updated 68687 APPROVED
2016-03-16 T2DN-Sirt3em25Mcwi    T2DN-Sirt3em25Mcwi    Symbol updated 68687 APPROVED
2016-03-16 T2DN-Sirt3em25Mcwi    T2DN-Sirt3em25Mcwi    Name updated 68913 APPROVED
2016-03-16 T2DN-Sirt3em25Mcwi    T2DN-Sirt3em25Mcwi    Name updated 68913 APPROVED
2015-08-26 T2DN-Sirt3em25Mcwi    T2DN-Sirt35em25Mcwi    Name updated 68913 APPROVED
2015-08-26 T2DN-Sirt3em25Mcwi    T2DN-Sirt35em25Mcwi    Name updated 68913 APPROVED
2015-08-26 T2DN-Sirt3em25Mcwi    T2DN-Sirt35em25Mcwi    Symbol updated 68687 APPROVED
2015-08-26 T2DN-Sirt3em25Mcwi    T2DN-Sirt35em25Mcwi    Symbol updated 68687 APPROVED
2015-08-06 T2DN-Sirt35em25Mcwi    SS-Sirt35em25Mcwi    Symbol updated 68687 APPROVED
2015-08-06 T2DN-Sirt35em25Mcwi    SS-Sirt35em25Mcwi    Name updated 68913 APPROVED
2015-08-06 T2DN-Sirt35em25Mcwi    SS-Sirt35em25Mcwi    Symbol updated 68687 APPROVED
2015-08-06 T2DN-Sirt35em25Mcwi    SS-Sirt35em25Mcwi    Name updated 68913 APPROVED