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Gene: Csf1r (colony stimulating factor 1 receptor) Rattus norvegicus
Symbol: Csf1r
Name: colony stimulating factor 1 receptor
Description: Predicted to have several functions, including macrophage colony-stimulating factor receptor activity; protein homodimerization activity; and protein phosphatase binding activity. Involved in several processes, including positive regulation of osteoclast differentiation; regulation of bone resorption; and skeletal muscle tissue development. Predicted to localize to several cellular components, including CSF1-CSF1R complex; cell surface; and nucleoplasm. Used to study anti-basement membrane glomerulonephritis. Human ortholog(s) of this gene implicated in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia and renal cell carcinoma. Orthologous to human CSF1R (colony stimulating factor 1 receptor); PARTICIPATES IN cytokine mediated signaling pathway; endocytosis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
Also known as: c-fms; CSF-1 receptor; CSF-1-R; CSF-1R; fms proto-oncogene; M-CSF-R; macrophage colony-stimulating factor 1 receptor; MGC125014; mrfms; proto-oncogene c-Fms; proto-oncogene fms
Homo sapiens (human) : CSF1R (colony stimulating factor 1 receptor)  HGNC  Alliance
Mus musculus (house mouse) : Csf1r (colony stimulating factor 1 receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf1r (colony stimulating factor 1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF1R (colony stimulating factor 1 receptor)
Canis lupus familiaris (dog) : CSF1R (colony stimulating factor 1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf1r (colony stimulating factor 1 receptor)
Sus scrofa (pig) : CSF1R (colony stimulating factor 1 receptor)
Chlorocebus sabaeus (African green monkey) : CSF1R (colony stimulating factor 1 receptor)
Heterocephalus glaber (naked mole-rat) : Csf1r (colony stimulating factor 1 receptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01856,414,493 - 56,458,300 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1856,414,488 - 56,458,300 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01855,662,670 - 55,689,297 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41857,080,324 - 57,107,295 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1852,716,221 - 52,742,736 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Csf1r
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2425
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.