Strain Report - Rat Genome Database

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Strain: SS-Nox4em2Mcwi-/+

Symbol: SS-Nox4em2Mcwi-/+
Strain: SS-Nox4em2-/Nox4em2+
Substrain: Mcwi
Full Name: SS-Nox4em2Mcwi-/Nox4em2Mcwi+
RGD ID: 5688080
Citation ID: RRID:RGD_5688080
Ontology ID: RS:0003128
Alleles: Nox4em2Mcwi
Also Known As: SS-Nox4em2Mcwi-/+; SS-Nox4em2Mcwi/2Mcwi; SS-Nox4em2Mcwi/2Mcwi; SS-Nox4em2Mcwi-/Nox4em2Mcwi+; SS-Nox4^[em2Mcwi-/+]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Genetic Status: Heterozygous
Last Known Status: Live Animals; Cryopreserved Sperm (as of 2019-07-26)
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21140,900,886 - 141,078,844RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01150,861,996 - 150,862,003RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01157,106,652 - 157,285,107RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41143,415,816 - 143,603,554RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Nox4em2Mcwi-var1 chr1 150861996 150862003 ACCTATGC - deletion Rnor_6.0

Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-31 SS-Nox4em2Mcwi-/+  SS-Nox4em2Mcwi-/Nox4em2Mcwi+  SS-Nox4em2Mcwi-/+  SS-Nox4em2Mcwi-/Nox4em2Mcwi+  Symbol and/or name change 68913 APPROVED