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Strain Registration

Strain: WKY-Jundem1Tja

Symbol: WKY-Jundem1Tja
Strain: WKY-Jundem1
Substrain: Tja
RGD ID: 11084928
Citation ID: RRID:RRRC_00755
Ontology ID: RS:0004190
Alleles: Jundem1Tja
Previously known as: WKY-Jundem1Tja; WKY JunD KO
Type: mutant
Source: Rat Resource and Research Center
Origin: The mutation was generated using zinc finger nuclease technology. The mutation involves insertion of one extra C at position 16:20486368 in the intronless JunD gene (Rat (Rnor_6.0)Ensembl) resulting in a null mutation.
Genetic Status: Heterozygous
Coat Color: white
Last Known Status: Cryopreserved Sperm (as of 2017-01-26)
Research Usage leukemia, breast cancer
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,734,121 - 18,735,799RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01620,485,028 - 20,486,707RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01620,342,096 - 20,343,775RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41619,239,694 - 19,241,529RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Data registered by the Rat Resource & Research Center Personal Communication with Rat Resource & Research Center
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other Jund is a member of the JUN family, and a functional component of the AP1 transcription factor complex. Diseases associated with JUND include human t-cell leukemia virus type 1 and breast cancer. Among its related pathways are MAPK signaling pathway and Akt Signaling. 2292495
strain_other The mutation is a null mutation. Homozygotes do not produce the Jund protein based on Western blot analysis. 2292495
strain_reproduction sib-mating; replace breeding pair after 6 litters or 6 months, whatever comes first. 2292495
Database Acc Id Source(s)
RRRC RRRC:00755 RGD