Gene: Ace (angiotensin I converting enzyme) Rattus norvegicus
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Symbol: Ace
Name: angiotensin I converting enzyme
Description: ENCODES a protein that exhibits drug binding; metallopeptidase activity; peptidyl-dipeptidase activity; INVOLVED IN aging; angiogenesis involved in coronary vascular morphogenesis; animal organ regeneration; PARTICIPATES IN angiotensin (1-7) signaling pathway; renin-angiotensin cascade pathway; angiotensin II signaling pathway; ASSOCIATED WITH decreased angiotensin I-converting enzyme activity; increased angiotensin I-converting enzyme activity; ASSOCIATED WITH abdominal aortic aneurysm; acute kidney failure; Albuminuria; FOUND IN basal plasma membrane; brush border membrane; extracellular space; INTERACTS WITH (R)-lipoic acid; (S)-colchicine; 14,15-EET
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: angiotensin 1 converting enzyme; angiotensin 1 converting enzyme 1; angiotensin converting enzyme; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I converting enzyme 1; angiotensin I-converting enzyme (Dipeptidyl carboxypeptidase 1); angiotensin-converting enzyme; CD143; Dcp1; Dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase 1 (Angiotensin I-converting enzyme); dipeptidyl carboxypeptidase I; kininase II; StsRR92
Orthologs:
Homo sapiens (human) : ACE (angiotensin I converting enzyme)  HGNC  Alliance
Mus musculus (house mouse) : Ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1)  MGI  Alliance
Canis lupus familiaris (dog) : ACE (angiotensin I converting enzyme)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101968921 (angiotensin-converting enzyme)
Sus scrofa (pig) : ACE (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1)
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Allele / Splice: Aceem1Mcwi   Aceem2Mcwi  
Genetic Models: SS-Aceem1Mcwi SS-Aceem2Mcwi
Is Marker For: Strains:   SD-Tg(Ren2)27   SS.MNS-(D10M11Mit119-D10Mit11)/Jr   LOU.BN-(D10Mgh1-D10Mgh14)/Ins  
QTLs:   Bp9   Bw57   Bp342   Bw102  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01094,170,766 - 94,213,831 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01093,922,062 - 93,965,127 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41095,361,338 - 95,381,455 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1089,588,544 - 89,608,666 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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More on Ace
Alliance Gene
NCBI Gene
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JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 2493
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE



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