RGD Reference Report - The genetic association database. - Rat Genome Database

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The genetic association database.

Authors: Becker, Kevin G  Barnes, Kathleen C  Bright, Tiffani J  Wang, S Alex 
Citation: Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
RGD ID: 1331525
Pubmed: (View Article at PubMed) PMID:15118671
DOI: Full-text: DOI:10.1038/ng0504-431

Abstract for this paper unavailable

Annotation

Disease Annotations    
acquired immunodeficiency syndrome  (IEA,ISO)
Addison's disease  (IEA,ISO)
adult respiratory distress syndrome  (IEA,ISO)
adult T-cell leukemia  (IEA,ISO)
Albuminuria  (IEA,ISO)
alcohol use disorder  (IEA)
alcoholic cardiomyopathy  (IEA,ISO)
Alzheimer's disease  (IEA,ISO)
arteriosclerosis  (IEA,ISO)
asthma  (IEA,ISO)
atopic dermatitis  (IEA,ISO)
autoimmune hepatitis  (IEA,ISO)
bipolar disorder  (IEA,ISO)
Brain Injuries  (IEA,ISO)
Breast Neoplasms  (IEA,ISO)
Bronchial Hyperreactivity  (IEA,ISO)
cardiovascular system disease  (IEA,ISO)
carotid artery disease  (IEA,ISO)
cerebral amyloid angiopathy  (IEA,ISO)
chronic obstructive pulmonary disease  (IEA,ISO)
Colorectal Neoplasms  (IEA,ISO)
coronary artery disease  (IEA,ISO)
Coronary Disease  (IEA,ISO)
Crohn's disease  (IEA,ISO)
cystic fibrosis  (IEA,ISO)
dementia  (IEA,ISO)
Diabetic Nephropathies  (IEA,ISO)
diabetic retinopathy  (IEA,ISO)
end stage renal disease  (IEA,ISO)
familial adenomatous polyposis  (IEA,ISO)
Familial Amyloid Polyneuropathies  (IEA,ISO)
Familial Amyloidosis  (IEA,ISO)
familial hyperlipidemia  (IEA,ISO)
focal epilepsy  (IEA,ISO)
glaucoma  (IEA,ISO)
glycogen storage disease III  (IEA,ISO)
Graves' disease  (IEA,ISO)
hepatocellular carcinoma  (IEA,ISO)
Hypercholesterolemia  (IEA,ISO)
Hyperlipoproteinemia Type II  (IEA,ISO)
hyperlipoproteinemia type III  (IEA,ISO)
Hyperlipoproteinemias  (IEA,ISO)
hypertension  (IEA,ISO)
Hypertriglyceridemia  (IEA,ISO)
IgA glomerulonephritis  (IEA,ISO)
Insulin Resistance  (IEA,ISO)
Intervertebral Disc Displacement  (IEA,ISO)
intracranial aneurysm  (IEA,ISO)
Kaposi's sarcoma  (IEA,ISO)
Knee Osteoarthritis  (IEA,ISO)
Left Ventricular Hypertrophy  (IEA,ISO)
lepromatous leprosy  (IEA,ISO)
Lung Neoplasms  (IEA,ISO)
macular degeneration  (IEA,ISO)
marginal zone B-cell lymphoma  (IEA,ISO)
melanoma  (IEA,ISO)
Memory Disorders  (IEA,ISO)
mental depression  (IEA)
Metabolic Syndrome  (IEA,ISO)
mitral valve prolapse  (IEA,ISO)
multiple sclerosis  (IEA,ISO,TAS)
myocardial infarction  (IEA,ISO)
Nasopharyngeal Neoplasms  (IEA,ISO)
Neoplasm Metastasis  (IEA,ISO)
nephroblastoma  (IEA,ISO)
neural tube defect  (IEA,ISO)
obesity  (IEA,ISO)
Ovarian Neoplasms  (IEA,ISO)
panic disorder  (IEA,ISO)
Parkinson's disease  (IEA,ISO)
periodontitis  (IEA,ISO)
peripheral vascular disease  (IEA,ISO)
Postmenopausal Osteoporosis  (IEA,ISO)
Presbycusis  (IEA,ISO)
primary biliary cholangitis  (IEA,ISO)
Prostatic Neoplasms  (IEA,ISO)
psoriasis  (IEA,ISO)
renal cell carcinoma  (IEA,ISO)
rheumatoid arthritis  (IEA,ISO)
sarcoidosis  (IEA,ISO)
sarcoma  (IEA,ISO)
schizophrenia  (IEA,ISO)
sleep apnea  (IEA,ISO)
Stroke  (IEA,ISO)
Subarachnoid Hemorrhage  (IEA,ISO)
systemic lupus erythematosus  (IEA,ISO)
systemic scleroderma  (IEA,ISO)
Thyroid Neoplasms  (IEA,ISO)
tuberculoid leprosy  (IEA,ISO)
tuberculosis  (IEA,ISO)
type 1 diabetes mellitus  (IEA,ISO)
type 2 diabetes mellitus  (IEA,ISO)
ulcerative colitis  (IEA,ISO)
Urinary Calculi  (IEA,ISO)
von Willebrand's disease  (IEA,ISO)
WAGR syndrome  (IEA,ISO)
xeroderma pigmentosum  (IEA,ISO)

Objects Annotated

Genes (Rattus norvegicus)
A2m  (alpha-2-macroglobulin)
Abca1  (ATP binding cassette subfamily A member 1)
Abcc6  (ATP binding cassette subfamily C member 6)
Ace  (angiotensin I converting enzyme)
Actg1  (actin, gamma 1)
Adam33  (ADAM metallopeptidase domain 33)
Add1  (adducin 1)
Add2  (adducin 2)
Adora1  (adenosine A1 receptor)
Adora2a  (adenosine A2a receptor)
Adra2a  (adrenoceptor alpha 2A)
Adrb1  (adrenoceptor beta 1)
Adrb2  (adrenoceptor beta 2)
Adrb3  (adrenoceptor beta 3)
Ager  (advanced glycosylation end product-specific receptor)
Agl  (amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase)
Agrp  (agouti related neuropeptide)
Agt  (angiotensinogen)
Agtr1a  (angiotensin II receptor, type 1a)
Aldh2  (aldehyde dehydrogenase 2 family member)
Alox5  (arachidonate 5-lipoxygenase)
Alox5ap  (arachidonate 5-lipoxygenase activating protein)
Apc  (APC regulator of WNT signaling pathway)
Apoa1  (apolipoprotein A1)
Apoa4  (apolipoprotein A4)
Apoa5  (apolipoprotein A5)
Apob  (apolipoprotein B)
Apoc3  (apolipoprotein C3)
Apoe  (apolipoprotein E)
Ar  (androgen receptor)
Bche  (butyrylcholinesterase)
Bdkrb2  (bradykinin receptor B2)
Bdnf  (brain-derived neurotrophic factor)
Cyba  (cytochrome b-245 alpha chain)
Dpp10  (dipeptidyl peptidase like 10)
Drd2  (dopamine receptor D2)
Drd4  (dopamine receptor D4)
Ercc2  (ERCC excision repair 2, TFIIH core complex helicase subunit)
Esr1  (estrogen receptor 1)
Fgb  (fibrinogen beta chain)
Gc  (GC, vitamin D binding protein)
Gnas  (GNAS complex locus)
Gstm1  (glutathione S-transferase mu 1)
Gstm2  (glutathione S-transferase mu 2)
Gstp1  (glutathione S-transferase pi 1)
Hsd11b1  (hydroxysteroid 11-beta dehydrogenase 1)
Htr2a  (5-hydroxytryptamine receptor 2A)
Ifng  (interferon gamma)
Irs2  (insulin receptor substrate 2)
Ldlr  (low density lipoprotein receptor)
Lep  (leptin)
Lepr  (leptin receptor)
Lipc  (lipase C, hepatic type)
LOC100361457  (actin, gamma 1 propeptide-like)
Mc3r  (melanocortin 3 receptor)
Mc4r  (melanocortin 4 receptor)
Npy5r  (neuropeptide Y receptor Y5)
Nr3c1  (nuclear receptor subfamily 3, group C, member 1)
Pparg  (peroxisome proliferator-activated receptor gamma)
Psen1  (presenilin 1)
Psmb8  (proteasome 20S subunit beta 8)
Slc11a1  (solute carrier family 11 member 1)
Srd5a2  (steroid 5 alpha-reductase 2)
Tap1  (transporter 1, ATP binding cassette subfamily B member)
Tbxa2r  (thromboxane A2 receptor)
Tgfb1  (transforming growth factor, beta 1)
Tp53  (tumor protein p53)
Ttr  (transthyretin)
Ucp3  (uncoupling protein 3)
Vdr  (vitamin D receptor)
Vwf  (von Willebrand factor)
Wt1  (WT1 transcription factor)
Xpa  (XPA, DNA damage recognition and repair factor)
Xrcc1  (X-ray repair cross complementing 1)
Xrcc3  (X-ray repair cross complementing 3)
Ywhab  (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta)
Ywhah  (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta)
Zdhhc8  (zinc finger DHHC-type palmitoyltransferase 8)
Zic2  (Zic family member 2)

Genes (Mus musculus)
A2m  (alpha-2-macroglobulin)
Abca1  (ATP-binding cassette, sub-family A (ABC1), member 1)
Abcc6  (ATP-binding cassette, sub-family C (CFTR/MRP), member 6)
Ace  (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1)
Actg1  (actin, gamma, cytoplasmic 1)
Adam33  (a disintegrin and metallopeptidase domain 33)
Add1  (adducin 1 (alpha))
Add2  (adducin 2 (beta))
Adora1  (adenosine A1 receptor)
Adora2a  (adenosine A2a receptor)
Adra2a  (adrenergic receptor, alpha 2a)
Adrb1  (adrenergic receptor, beta 1)
Adrb2  (adrenergic receptor, beta 2)
Adrb3  (adrenergic receptor, beta 3)
Ager  (advanced glycosylation end product-specific receptor)
Agl  (amylo-1,6-glucosidase, 4-alpha-glucanotransferase)
Agrp  (agouti related neuropeptide)
Agt  (angiotensinogen (serpin peptidase inhibitor, clade A, member 8))
Agtr1a  (angiotensin II receptor, type 1a)
Aldh2  (aldehyde dehydrogenase 2, mitochondrial)
Alox5  (arachidonate 5-lipoxygenase)
Alox5ap  (arachidonate 5-lipoxygenase activating protein)
Apc  (APC, WNT signaling pathway regulator)
Apoa1  (apolipoprotein A-I)
Apoa4  (apolipoprotein A-IV)
Apoa5  (apolipoprotein A-V)
Apob  (apolipoprotein B)
Apoc3  (apolipoprotein C-III)
Apoe  (apolipoprotein E)
Ar  (androgen receptor)
Bche  (butyrylcholinesterase)
Bdkrb2  (bradykinin receptor, beta 2)
Bdnf  (brain derived neurotrophic factor)
Cyba  (cytochrome b-245, alpha polypeptide)
Dpp10  (dipeptidylpeptidase 10)
Drd2  (dopamine receptor D2)
Drd4  (dopamine receptor D4)
Ercc2  (excision repair cross-complementing rodent repair deficiency, complementation group 2)
Esr1  (estrogen receptor 1 (alpha))
Fgb  (fibrinogen beta chain)
Gc  (vitamin D binding protein)
Gnas  (GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus)
Gstm1  (glutathione S-transferase, mu 1)
Gstm2  (glutathione S-transferase, mu 2)
Gstp1  (glutathione S-transferase, pi 1)
Hsd11b1  (hydroxysteroid 11-beta dehydrogenase 1)
Htr2a  (5-hydroxytryptamine (serotonin) receptor 2A)
Ifng  (interferon gamma)
Irs2  (insulin receptor substrate 2)
Ldlr  (low density lipoprotein receptor)
Lep  (leptin)
Lepr  (leptin receptor)
Lipc  (lipase, hepatic)
Mc3r  (melanocortin 3 receptor)
Mc4r  (melanocortin 4 receptor)
Npy5r  (neuropeptide Y receptor Y5)
Nr3c1  (nuclear receptor subfamily 3, group C, member 1)
Pparg  (peroxisome proliferator activated receptor gamma)
Psen1  (presenilin 1)
Psmb8  (proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7))
Slc11a1  (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1)
Srd5a2  (steroid 5 alpha-reductase 2)
Tap1  (transporter 1, ATP-binding cassette, sub-family B (MDR/TAP))
Tbxa2r  (thromboxane A2 receptor)
Tgfb1  (transforming growth factor, beta 1)
Trp53  (transformation related protein 53)
Ttr  (transthyretin)
Ucp3  (uncoupling protein 3 (mitochondrial, proton carrier))
Vdr  (vitamin D (1,25-dihydroxyvitamin D3) receptor)
Vwf  (Von Willebrand factor)
Wt1  (WT1 transcription factor)
Xpa  (xeroderma pigmentosum, complementation group A)
Xrcc1  (X-ray repair complementing defective repair in Chinese hamster cells 1)
Xrcc3  (X-ray repair complementing defective repair in Chinese hamster cells 3)
Ywhab  (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide)
Ywhah  (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide)
Zic2  (zinc finger protein of the cerebellum 2)

Genes (Homo sapiens)
A2M  (alpha-2-macroglobulin)
ABCA1  (ATP binding cassette subfamily A member 1)
ABCC6  (ATP binding cassette subfamily C member 6)
ACE  (angiotensin I converting enzyme)
ACTG1  (actin gamma 1)
ADAM33  (ADAM metallopeptidase domain 33)
ADD1  (adducin 1)
ADD2  (adducin 2)
ADORA1  (adenosine A1 receptor)
ADORA2A  (adenosine A2a receptor)
ADRA2A  (adrenoceptor alpha 2A)
ADRB1  (adrenoceptor beta 1)
ADRB2  (adrenoceptor beta 2)
ADRB3  (adrenoceptor beta 3)
AGER  (advanced glycosylation end-product specific receptor)
AGL  (amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase)
AGRP  (agouti related neuropeptide)
AGT  (angiotensinogen)
AGTR1  (angiotensin II receptor type 1)
ALDH2  (aldehyde dehydrogenase 2 family member)
ALOX5  (arachidonate 5-lipoxygenase)
ALOX5AP  (arachidonate 5-lipoxygenase activating protein)
APC  (APC regulator of WNT signaling pathway)
APOA1  (apolipoprotein A1)
APOA4  (apolipoprotein A4)
APOA5  (apolipoprotein A5)
APOB  (apolipoprotein B)
APOC3  (apolipoprotein C3)
APOE  (apolipoprotein E)
AR  (androgen receptor)
BCHE  (butyrylcholinesterase)
BDKRB2  (bradykinin receptor B2)
BDNF  (brain derived neurotrophic factor)
CYBA  (cytochrome b-245 alpha chain)
DPP10  (dipeptidyl peptidase like 10)
DRD2  (dopamine receptor D2)
DRD4  (dopamine receptor D4)
ERCC2  (ERCC excision repair 2, TFIIH core complex helicase subunit)
ESR1  (estrogen receptor 1)
FGB  (fibrinogen beta chain)
GC  (GC vitamin D binding protein)
GNAS  (GNAS complex locus)
GSTM1  (glutathione S-transferase mu 1)
GSTM5  (glutathione S-transferase mu 5)
GSTP1  (glutathione S-transferase pi 1)
HSD11B1  (hydroxysteroid 11-beta dehydrogenase 1)
HTR2A  (5-hydroxytryptamine receptor 2A)
IFNG  (interferon gamma)
IRS2  (insulin receptor substrate 2)
LDLR  (low density lipoprotein receptor)
LEP  (leptin)
LEPR  (leptin receptor)
LIPC  (lipase C, hepatic type)
MC3R  (melanocortin 3 receptor)
MC4R  (melanocortin 4 receptor)
NPY5R  (neuropeptide Y receptor Y5)
NR3C1  (nuclear receptor subfamily 3 group C member 1)
POTEI  (POTE ankyrin domain family member I)
PPARG  (peroxisome proliferator activated receptor gamma)
PSEN1  (presenilin 1)
PSMB8  (proteasome 20S subunit beta 8)
SLC11A1  (solute carrier family 11 member 1)
SRD5A2  (steroid 5 alpha-reductase 2)
TAP1  (transporter 1, ATP binding cassette subfamily B member)
TBXA2R  (thromboxane A2 receptor)
TGFB1  (transforming growth factor beta 1)
TP53  (tumor protein p53)
TTR  (transthyretin)
UCP3  (uncoupling protein 3)
VDR  (vitamin D receptor)
VWF  (von Willebrand factor)
WT1  (WT1 transcription factor)
XPA  (XPA, DNA damage recognition and repair factor)
XRCC1  (X-ray repair cross complementing 1)
XRCC3  (X-ray repair cross complementing 3)
YWHAB  (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta)
YWHAH  (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)
ZDHHC8  (zinc finger DHHC-type palmitoyltransferase 8)
ZIC2  (Zic family member 2)

Objects referenced in this article
Gene EDN1 endothelin 1 Homo sapiens
Gene Edn1 endothelin 1 Rattus norvegicus
Gene LOC24906 RoBo-1 Rattus norvegicus

Additional Information