The genetic association database. |
Authors: |
Becker, Kevin G Barnes, Kathleen C Bright, Tiffani J Wang, S Alex
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Citation: |
Becker KG, etal., Nat Genet. 2004 May;36(5):431-2. |
RGD ID: |
1331525 |
Pubmed: |
PMID:15118671 (View Abstract at PubMed) |
DOI: |
DOI:10.1038/ng0504-431 (Journal Full-text) |
Abstract for this paper unavailable
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Imported Disease Annotations - GAD
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acquired immunodeficiency syndrome (IEA,ISO) | Addison's disease (IEA,ISO) | adult respiratory distress syndrome (IEA,ISO) | adult T-cell leukemia/lymphoma (IEA,ISO) | Albuminuria (IEA,ISO) | alcohol use disorder (IEA) | alcoholic cardiomyopathy (IEA,ISO) | Alzheimer's disease (IEA,ISO) | arteriosclerosis (IEA,ISO) | asthma (IEA,ISO) | atopic dermatitis (IEA,ISO) | autoimmune hepatitis (IEA,ISO) | bipolar disorder (IEA,ISO) | Brain Injuries (IEA,ISO) | Breast Neoplasms (IEA,ISO) | Bronchial Hyperreactivity (IEA,ISO) | cardiovascular system disease (IEA,ISO) | carotid artery disease (IEA,ISO) | cerebral amyloid angiopathy (IEA,ISO) | chronic obstructive pulmonary disease (IEA,ISO) | Colorectal Neoplasms (IEA,ISO) | coronary artery disease (IEA,ISO) | Coronary Disease (IEA,ISO) | Crohn's disease (IEA,ISO) | cystic fibrosis (IEA,ISO) | dementia (IEA,ISO) | depressive disorder (IEA) | Diabetic Nephropathies (IEA,ISO) | diabetic retinopathy (IEA,ISO) | end stage renal disease (IEA,ISO) | familial adenomatous polyposis (IEA,ISO) | Familial Amyloid Polyneuropathies (IEA,ISO) | Familial Amyloidosis (IEA,ISO) |
| familial hyperlipidemia (IEA,ISO) | focal epilepsy (IEA,ISO) | glaucoma (IEA,ISO) | glycogen storage disease III (IEA,ISO) | Graves' disease (IEA,ISO) | hepatocellular carcinoma (IEA,ISO) | Hypercholesterolemia (IEA,ISO) | Hyperlipoproteinemia Type II (IEA,ISO) | hyperlipoproteinemia type III (IEA,ISO) | Hyperlipoproteinemias (IEA,ISO) | hypertension (IEA,ISO) | Hypertriglyceridemia (IEA,ISO) | IgA glomerulonephritis (IEA,ISO) | Insulin Resistance (IEA,ISO) | Intervertebral Disc Displacement (IEA,ISO) | intracranial aneurysm (IEA,ISO) | Kaposi's sarcoma (IEA,ISO) | Knee Osteoarthritis (IEA,ISO) | Left Ventricular Hypertrophy (IEA,ISO) | lepromatous leprosy (IEA,ISO) | Lung Neoplasms (IEA,ISO) | macular degeneration (IEA,ISO) | marginal zone lymphoma (IEA,ISO) | melanoma (IEA,ISO) | Memory Disorders (IEA,ISO) | Metabolic Syndrome (IEA,ISO) | mitral valve prolapse (IEA,ISO) | multiple sclerosis (IEA,ISO,TAS) | myocardial infarction (IEA,ISO) | Nasopharyngeal Neoplasms (IEA,ISO) | Neoplasm Metastasis (IEA,ISO) | nephroblastoma (IEA,ISO) | neural tube defect (IEA,ISO) |
| obesity (IEA,ISO) | Ovarian Neoplasms (IEA,ISO) | panic disorder (IEA,ISO) | Parkinson's disease (IEA,ISO) | periodontitis (IEA,ISO) | peripheral vascular disease (IEA,ISO) | Postmenopausal Osteoporosis (IEA,ISO) | Presbycusis (IEA,ISO) | primary biliary cholangitis (IEA,ISO) | Prostatic Neoplasms (IEA,ISO) | psoriasis (IEA,ISO) | renal cell carcinoma (IEA,ISO) | rheumatoid arthritis (IEA,ISO) | sarcoidosis (IEA,ISO) | sarcoma (IEA,ISO) | schizophrenia (IEA,ISO) | sleep apnea (IEA,ISO) | Stroke (IEA,ISO) | Subarachnoid Hemorrhage (IEA,ISO) | systemic lupus erythematosus (IEA,ISO) | systemic scleroderma (IEA,ISO) | Thyroid Neoplasms (IEA,ISO) | tuberculoid leprosy (IEA,ISO) | tuberculosis (IEA,ISO) | type 1 diabetes mellitus (IEA,ISO) | type 2 diabetes mellitus (IEA,ISO) | ulcerative colitis (IEA,ISO) | Urinary Calculi (IEA,ISO) | von Willebrand's disease (IEA,ISO) | WAGR syndrome (IEA,ISO) | xeroderma pigmentosum (IEA,ISO) |
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Objects Annotated
Genes (Rattus norvegicus) |
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A2m (alpha-2-macroglobulin) | Abca1 (ATP binding cassette subfamily A member 1) | Abcc6 (ATP binding cassette subfamily C member 6) | Ace (angiotensin I converting enzyme) | Actg1 (actin, gamma 1) | Actg1l1 (actin, gamma 1 like 1) | Adam33 (ADAM metallopeptidase domain 33) | Add1 (adducin 1) | Add2 (adducin 2) | Adora1 (adenosine A1 receptor) | Adora2a (adenosine A2a receptor) | Adra2a (adrenoceptor alpha 2A) | Adrb1 (adrenoceptor beta 1) | Adrb2 (adrenoceptor beta 2) | Adrb3 (adrenoceptor beta 3) | Ager (advanced glycosylation end product-specific receptor) | Agl (amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase) | Agrp (agouti related neuropeptide) | Agt (angiotensinogen) | Agtr1a (angiotensin II receptor, type 1a) | Aldh2 (aldehyde dehydrogenase 2 family member) | Alox5 (arachidonate 5-lipoxygenase) | Alox5ap (arachidonate 5-lipoxygenase activating protein) | Apc (APC regulator of WNT signaling pathway) | Apoa1 (apolipoprotein A1) | Apoa4 (apolipoprotein A4) | Apoa5 (apolipoprotein A5) |
| Apob (apolipoprotein B) | Apoc3 (apolipoprotein C3) | Apoe (apolipoprotein E) | Ar (androgen receptor) | Bche (butyrylcholinesterase) | Bdkrb2 (bradykinin receptor B2) | Bdnf (brain-derived neurotrophic factor) | Cyba (cytochrome b-245 alpha chain) | Dpp10 (dipeptidyl peptidase like 10) | Drd2 (dopamine receptor D2) | Drd4 (dopamine receptor D4) | Ercc2 (ERCC excision repair 2, TFIIH core complex helicase subunit) | Esr1 (estrogen receptor 1) | Fgb (fibrinogen beta chain) | Gc (GC, vitamin D binding protein) | Gnas (GNAS complex locus) | Gstm1 (glutathione S-transferase mu 1) | Gstm2 (glutathione S-transferase mu 2) | Gstp1 (glutathione S-transferase pi 1) | Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1) | Htr2a (5-hydroxytryptamine receptor 2A) | Ifng (interferon gamma) | Irs2 (insulin receptor substrate 2) | Ldlr (low density lipoprotein receptor) | Lep (leptin) | Lepr (leptin receptor) | Lipc (lipase C, hepatic type) |
| Mc3r (melanocortin 3 receptor) | Mc4r (melanocortin 4 receptor) | Npy5r (neuropeptide Y receptor Y5) | Nr3c1 (nuclear receptor subfamily 3, group C, member 1) | Pparg (peroxisome proliferator-activated receptor gamma) | Psen1 (presenilin 1) | Psmb8 (proteasome 20S subunit beta 8) | Slc11a1 (solute carrier family 11 member 1) | Srd5a2 (steroid 5 alpha-reductase 2) | Tap1 (transporter 1, ATP binding cassette subfamily B member) | Tbxa2r (thromboxane A2 receptor) | Tgfb1 (transforming growth factor, beta 1) | Tp53 (tumor protein p53) | Ttr (transthyretin) | Ucp3 (uncoupling protein 3) | Vdr (vitamin D receptor) | Vwf (von Willebrand factor) | Wt1 (WT1 transcription factor) | Xpa (XPA, DNA damage recognition and repair factor) | Xrcc1 (X-ray repair cross complementing 1) | Xrcc3 (X-ray repair cross complementing 3) | Ywhab (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta) | Ywhah (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta) | Zdhhc8 (zinc finger DHHC-type palmitoyltransferase 8) | Zic2 (Zic family member 2) |
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Genes (Mus musculus) |
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A2m (alpha-2-macroglobulin) | Abca1 (ATP-binding cassette, sub-family A member 1) | Abcc6 (ATP-binding cassette, sub-family C member 6) | Ace (angiotensin I converting enzyme) | Actg1 (actin, gamma, cytoplasmic 1) | Adam33 (a disintegrin and metallopeptidase domain 33) | Add1 (adducin 1) | Add2 (adducin 2) | Adora1 (adenosine A1 receptor) | Adora2a (adenosine A2a receptor) | Adra2a (adrenergic receptor, alpha 2a) | Adrb1 (adrenergic receptor, beta 1) | Adrb2 (adrenergic receptor, beta 2) | Adrb3 (adrenergic receptor, beta 3) | Ager (advanced glycosylation end product-specific receptor) | Agl (amylo-1,6-glucosidase, 4-alpha-glucanotransferase) | Agrp (agouti related neuropeptide) | Agt (angiotensinogen) | Agtr1a (angiotensin II receptor, type 1a) | Aldh2 (aldehyde dehydrogenase 2, mitochondrial) | Alox5 (arachidonate 5-lipoxygenase) | Alox5ap (arachidonate 5-lipoxygenase activating protein) | Apc (APC, WNT signaling pathway regulator) | Apoa1 (apolipoprotein A-I) | Apoa4 (apolipoprotein A-IV) | Apoa5 (apolipoprotein A-V) |
| Apob (apolipoprotein B) | Apoc3 (apolipoprotein C-III) | Apoe (apolipoprotein E) | Ar (androgen receptor) | Bche (butyrylcholinesterase) | Bdkrb2 (bradykinin receptor, beta 2) | Bdnf (brain derived neurotrophic factor) | Cyba (cytochrome b-245, alpha polypeptide) | Dpp10 (dipeptidylpeptidase 10) | Drd2 (dopamine receptor D2) | Drd4 (dopamine receptor D4) | Ercc2 (excision repair cross-complementing rodent repair deficiency, complementation group 2) | Esr1 (estrogen receptor 1 (alpha)) | Fgb (fibrinogen beta chain) | Gc (vitamin D binding protein) | Gnas (GNAS complex locus) | Gstm1 (glutathione S-transferase, mu 1) | Gstm2 (glutathione S-transferase, mu 2) | Gstp1 (glutathione S-transferase, pi 1) | Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1) | Htr2a (5-hydroxytryptamine (serotonin) receptor 2A) | Ifng (interferon gamma) | Irs2 (insulin receptor substrate 2) | Ldlr (low density lipoprotein receptor) | Lep (leptin) | Lepr (leptin receptor) |
| Lipc (lipase, hepatic) | Mc3r (melanocortin 3 receptor) | Mc4r (melanocortin 4 receptor) | Npy5r (neuropeptide Y receptor Y5) | Nr3c1 (nuclear receptor subfamily 3, group C, member 1) | Pparg (peroxisome proliferator activated receptor gamma) | Psen1 (presenilin 1) | Psmb8 (proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)) | Slc11a1 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1) | Srd5a2 (steroid 5 alpha-reductase 2) | Tap1 (transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)) | Tbxa2r (thromboxane A2 receptor) | Tgfb1 (transforming growth factor, beta 1) | Trp53 (transformation related protein 53) | Ttr (transthyretin) | Ucp3 (uncoupling protein 3 (mitochondrial, proton carrier)) | Vdr (vitamin D (1,25-dihydroxyvitamin D3) receptor) | Vwf (Von Willebrand factor) | Wt1 (WT1 transcription factor) | Xpa (xeroderma pigmentosum, complementation group A) | Xrcc1 (X-ray repair complementing defective repair in Chinese hamster cells 1) | Xrcc3 (X-ray repair complementing defective repair in Chinese hamster cells 3) | Ywhab (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide) | Ywhah (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide) | Zic2 (zinc finger protein of the cerebellum 2) |
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Genes (Homo sapiens) |
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A2M (alpha-2-macroglobulin) | ABCA1 (ATP binding cassette subfamily A member 1) | ABCC6 (ATP binding cassette subfamily C member 6) | ACE (angiotensin I converting enzyme) | ACTG1 (actin gamma 1) | ADAM33 (ADAM metallopeptidase domain 33) | ADD1 (adducin 1) | ADD2 (adducin 2) | ADORA1 (adenosine A1 receptor) | ADORA2A (adenosine A2a receptor) | ADRA2A (adrenoceptor alpha 2A) | ADRB1 (adrenoceptor beta 1) | ADRB2 (adrenoceptor beta 2) | ADRB3 (adrenoceptor beta 3) | AGER (advanced glycosylation end-product specific receptor) | AGL (amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase) | AGRP (agouti related neuropeptide) | AGT (angiotensinogen) | AGTR1 (angiotensin II receptor type 1) | ALDH2 (aldehyde dehydrogenase 2 family member) | ALOX5 (arachidonate 5-lipoxygenase) | ALOX5AP (arachidonate 5-lipoxygenase activating protein) | APC (APC regulator of WNT signaling pathway) | APOA1 (apolipoprotein A1) | APOA4 (apolipoprotein A4) | APOA5 (apolipoprotein A5) | APOB (apolipoprotein B) |
| APOC3 (apolipoprotein C3) | APOE (apolipoprotein E) | AR (androgen receptor) | BCHE (butyrylcholinesterase) | BDKRB2 (bradykinin receptor B2) | BDNF (brain derived neurotrophic factor) | CYBA (cytochrome b-245 alpha chain) | DPP10 (dipeptidyl peptidase like 10) | DRD2 (dopamine receptor D2) | DRD4 (dopamine receptor D4) | ERCC2 (ERCC excision repair 2, TFIIH core complex helicase subunit) | ESR1 (estrogen receptor 1) | FGB (fibrinogen beta chain) | GC (GC vitamin D binding protein) | GNAS (GNAS complex locus) | GSTM1 (glutathione S-transferase mu 1) | GSTM5 (glutathione S-transferase mu 5) | GSTP1 (glutathione S-transferase pi 1) | HSD11B1 (hydroxysteroid 11-beta dehydrogenase 1) | HTR2A (5-hydroxytryptamine receptor 2A) | IFNG (interferon gamma) | IRS2 (insulin receptor substrate 2) | LDLR (low density lipoprotein receptor) | LEP (leptin) | LEPR (leptin receptor) | LIPC (lipase C, hepatic type) | MC3R (melanocortin 3 receptor) |
| MC4R (melanocortin 4 receptor) | NPY5R (neuropeptide Y receptor Y5) | NR3C1 (nuclear receptor subfamily 3 group C member 1) | POTEI (POTE ankyrin domain family member I) | PPARG (peroxisome proliferator activated receptor gamma) | PSEN1 (presenilin 1) | PSMB8 (proteasome 20S subunit beta 8) | SLC11A1 (solute carrier family 11 member 1) | SRD5A2 (steroid 5 alpha-reductase 2) | TAP1 (transporter 1, ATP binding cassette subfamily B member) | TBXA2R (thromboxane A2 receptor) | TGFB1 (transforming growth factor beta 1) | TP53 (tumor protein p53) | TTR (transthyretin) | UCP3 (uncoupling protein 3) | VDR (vitamin D receptor) | VWF (von Willebrand factor) | WT1 (WT1 transcription factor) | XPA (XPA, DNA damage recognition and repair factor) | XRCC1 (X-ray repair cross complementing 1) | XRCC3 (X-ray repair cross complementing 3) | YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) | YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta) | ZDHHC8 (zinc finger DHHC-type palmitoyltransferase 8) | ZIC2 (Zic family member 2) |
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Objects referenced in this article
Gene |
EDN1 |
endothelin 1 |
Homo sapiens |
Gene |
Edn1 |
endothelin 1 |
Rattus norvegicus |
Gene |
Lypd8l1 |
LY6/PLAUR domain containing 8 like 1 |
Rattus norvegicus |
Additional Information
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