Pia10 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Pia10 (Pristane induced arthritis QTL 10) Rattus norvegicus

Symbol: Pia10
Name: Pristane induced arthritis QTL 10
RGD ID: 61354
Trait: joint integrity trait   (VT:0010548)    
Measurement Type: joint inflammation composite score   (CMO:0000919)    
LOD Score: Not Available
P Value: 0.01
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81023,948,641 - 107,713,808RGD_MAPPER_PIPELINE
mRatBN7.21023,444,813 - 104,060,283RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01024,483,076 - 107,857,673RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01024,340,447 - 107,484,761RGDRnor5.0
RGSC_v3.41024,006,429 - 110,718,848RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.11024,007,478 - 110,733,352RGD
Cross Type: Congenic
Strains Crossed: DA.F344-(D10Arb20-D10Arb22)/Arb 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Hsd17b1 is a candidate Gene for Pia10
Prkca is a candidate Gene for Pia10
Stat3 is a candidate Gene for Pia10
Stat5a is a candidate Gene for Pia10
Stat5b is a candidate Gene for Pia10
Tnfaip1 is a candidate Gene for Pia10
Crhr1 is a candidate Gene for Pia10
Trim25 is a candidate Gene for Pia10


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pia10RatExperimental Arthritis  IDA 629569 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pia10Ratjoint swelling  QTM 61519 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pia10Ratjoint inflammation composite score  IDA 629569 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pia10Ratpristane  IDA 629569 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pia10Ratin vivo visual assessment  IDA 629569 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pia10RatDA.F344-(D10Arb20-D10Arb22)/Arb  IEA 629569 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pia10Ratjoint integrity trait  IDA 629569 RGD 


#
Reference Title
Reference Citation
1. COLLAGEN-INDUCED ARTHRITIS SEVERITY LOCI ON RAT CHROMOSOME 10 (RNO10) ALSO REGULATE DISEASE IN THREE OTHER EXPERIMENTALLY INDUCED MODELS OF ARTHRITIS Joe B., etal. 2000 Arthritis Rheum 43:S233
2. Modulation of multiple experimental arthritis models by collagen-induced arthritis quantitative trait loci isolated in congenic rat lines: different effects of non-major histocompatibility complex quantitative trait loci in males and females. Remmers EF, etal., Arthritis Rheum 2002 Aug;46(8):2225-34.
3. Identification of genomic regions controlling experimental autoimmune uveoretinitis in rats. Sun SH, etal., Int Immunol 1999 Apr;11(4):529-34

Related QTL Description Reference
Oia3 interacts with RGD:61519
Eau3 interacts with RGD:61073
Cia5 maps to same region RGD:61519
Aia5 interacts with RGD:61519



1 to 20 of 2033 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
41091800Trnaa-agc92transfer RNA alanine (anticodon AGC) 92102359142323591504Rat
41205966LOC120095254uncharacterized LOC120095254102407336024087187Rat
1588526Tpm1-ps1tropomyosin 1, pseudogene 1102420778924208973Rat
7728583LOC102547722uncharacterized LOC102547722102438651124410174Rat
2319678Snu13-ps1small nuclear ribonucleoprotein 13, pseudogene 1102441155924412088Rat
41238863Phb1-ps7prohibitin 1, pseudogene 7102465927924670076Rat
41252066LOC120095069uncharacterized LOC120095069102467030324672817Rat
9095316LOC10369330760S ribosomal protein L22-like 1 pseudogene102508838125095191Rat
1593534Mat2bmethionine adenosyltransferase 2 non-catalytic beta subunit102510692825122982Rat
2805Hmmrhyaluronan-mediated motility receptor102513293325163029Rat
1307203Nudcd2NudC domain containing 2102516324725168738Rat
41079045LOC120095494U4 spliceosomal RNA102516745825167624Rat
2295Ccng1cyclin G1102517623125182604Rat
41181179LOC120095070uncharacterized LOC120095070102521099925243816Rat
41332417Rpl32-ps12ribosomal protein L32, pseudogene 12102527599025278299Rat
1592316Api5-ps2apoptosis inhibitor 5, pseudogene 2102547255025474210Rat
9408823LOC103693305uncharacterized LOC103693305102607664326090717Rat
1591123Rps19-ps17ribosomal protein S19, pseudogene 17102609697226097422Rat
7615022LOC102548672uncharacterized LOC102548672102632406226428093Rat
61966Gabrg2gamma-aminobutyric acid type A receptor subunit gamma 2102637469326463937Rat

1 to 20 of 2033 rows
1 to 20 of 2654 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10062D10Wox19230108541268585412915Ratregion
10141D10Wox15254106322103763221291Ratregion
10142D10Arb9129106322109463221223Ratregion
10195D10Wox14158105477580754775965Ratregion
10196D10Mgh22270105477574554776015Ratregion
10662D10Wox23258108097644580976703Ratregion
10664D10Uwm1158105467188954672047Ratregion
10792D10Wox10850103840624038407090Ratregion
10794D10Mgh9130103777589037776020Ratregion
10795D10Wox9188103777583737776025Ratregion
10874D10Rat83173104539382945394002Ratregion
10926D10Wox21130108913584589135975Ratregion
10949D10Wox11150105178628251786432Ratregion
10980D10Wox16125108051612580516250Ratregion
10981D10Arb21199108051614780516346Ratregion
10982D10Mit13165108051613480516299Ratregion
10995D10Wox24138106381361463813752Ratregion
11137D10Wox17153108705512187055282Ratregion
11169D10Mgh21140108853913988539279Ratregion
33846D10Mit2188106364253963642727Ratregion
1 to 20 of 2654 rows

Flank 1: (D10Arb20)
Rat AssemblyChrPosition (strand)Source
GRCr81023,948,641 - 23,948,818 (+)Marker Load Pipeline
mRatBN7.21023,444,813 - 23,444,992 (+)MAPPER
Rnor_6.01024,483,076 - 24,483,258NCBI
Rnor_5.01024,340,447 - 24,340,629UniSTS
RGSC_v3.41024,006,429 - 24,006,612RGD
RGSC_v3.41024,006,430 - 24,006,612UniSTS
RGSC_v3.11024,007,478 - 24,007,661RGD
Celera1023,044,707 - 23,044,873UniSTS
Cytogenetic Map10 RGD
Peak: (D10Mit1)
Rat AssemblyChrPosition (strand)Source
GRCr81091,417,685 - 91,417,879 (+)Marker Load Pipeline
Rnor_5.01093,929,621 - 93,929,812NCBI
RGSC_v3.41095,368,898 - 95,369,088RGD
RGSC_v3.11095,383,268 - 95,383,458RGD
SHRSP x BN Map1068.71RGD
SHRSP x BN Map1068.71UniSTS
FHH x ACI Map1075.81RGD
Cytogenetic Map10q32.1UniSTS
Flank 2: (D10Arb22)
Rat AssemblyChrPosition (strand)Source
mRatBN7.210104,060,133 - 104,060,283 (+)MAPPER
Rnor_6.010107,857,524 - 107,857,673NCBI
Rnor_5.010107,484,612 - 107,484,761UniSTS
Celera10102,615,292 - 102,615,441UniSTS
Cytogenetic Map10q32.3UniSTS


1 to 10 of 204 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129497586Rat
12902615Bw185Body weight QTL 1850.01body mass (VT:0001259)body weight (CMO:0000012)107111521772606468Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
70168Eae12Experimental allergic encephalomyelitis QTL 120.0009nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1092238497101012337Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat

1 to 10 of 204 rows


Database
Acc Id
Source(s)
NCBI Gene Pia10

Note Type Note Reference
qtl_cross_type Congenic