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Gene: Vamp2 (vesicle-associated membrane protein 2) Rattus norvegicus
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Symbol: Vamp2
Name: vesicle-associated membrane protein 2
Description: Exhibits several functions, including ion channel binding activity; protein C-terminus binding activity; and syntaxin-1 binding activity. Involved in several processes, including SNARE complex assembly; exocytosis; and regulation of vesicle-mediated transport. Localizes to several cellular components, including the cytoplasm; neuron projection terminus; and plasma membrane. Colocalizes with the voltage-gated potassium channel complex. Orthologous to human VAMP2 (vesicle associated membrane protein 2); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; insulin secretion pathway; vasopressin signaling pathway; INTERACTS WITH 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: RATVAMPB; RATVAMPIR; SYB; Syb2; synaptobrevin 2; Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2); synaptobrevin-2; VAMP-2; Vesicle-associated membrane protein (synaptobrevin 2)
Orthologs:
Homo sapiens (human) : VAMP2 (vesicle associated membrane protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Vamp2 (vesicle-associated membrane protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vamp2 (vesicle associated membrane protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : VAMP2 (vesicle associated membrane protein 2)
Canis lupus familiaris (dog) : VAMP2 (vesicle associated membrane protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vamp2 (vesicle associated membrane protein 2)
Sus scrofa (pig) : VAMP2 (vesicle associated membrane protein 2)
more info ...
Is Marker For: Strains:   WKY.SHRSP-(Asgr1-Vamp2)/Bbb   SS.MNS-(D10Mit11-Vamp2)/Mco   SS.MNS-(Vamp2-D10M11Mit84)/Mco  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01055,675,171 - 55,679,405 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01055,418,231 - 55,422,465 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,848,264 - 55,852,132 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11055,861,886 - 55,865,753 (+)NCBI
Celera1052,959,486 - 52,963,354 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Vamp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3949
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.