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Gene: Slc9a3r1 (SLC9A3 regulator 1) Rattus norvegicus
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Symbol: Slc9a3r1
Name: SLC9A3 regulator 1
Description: Exhibits several functions, including PDZ domain binding activity; myosin II binding activity; and protein N-terminus binding activity. Involved in positive regulation of ion transmembrane transport. Localizes to several cellular components, including the apical plasma membrane; membrane raft; and microvillus membrane. Biomarker of hypertension. Human ortholog(s) of this gene implicated in hypophosphatemic nephrolithiasis/osteoporosis 2. Orthologous to human SLC9A3R1 (SLC9A3 regulator 1); PARTICIPATES IN eicosanoid signaling pathway; parathyroid hormone signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: EBP50; ERM-binding phosphoprotein; ezrin-radixin-moesin-binding phosphoprotein 50; LOC59114; na(+)/H(+) exchange regulatory cofactor NHE-RF1; NHERF-1; regulatory cofactor of Na(+)/H(+) exchanger; sodium-hydrogen exchanger regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1; solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1; solute carrier family 9 isoform A3 regulatory factor 1; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
Orthologs:
Homo sapiens (human) : SLC9A3R1 (SLC9A3 regulator 1)  HGNC  Alliance
Mus musculus (house mouse) : Slc9a3r1 (solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc9a3r1 (SLC9A3 regulator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC9A3R1 (SLC9A3 regulator 1)
Canis lupus familiaris (dog) : SLC9A3R1 (SLC9A3 regulator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc9a3r1 (SLC9A3 regulator 1)
Sus scrofa (pig) : SLC9A3R1 (SLC9A3 regulator 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010103,713,045 - 103,730,145 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010104,573,624 - 104,590,426 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410105,237,637 - 105,254,750 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110105,252,140 - 105,269,254 (+)NCBI
Celera1098,979,637 - 98,995,900 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc9a3r1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 708538
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.