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Gene: Slc9a3r1 (solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1) Mus musculus
Symbol: Slc9a3r1
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
Description: Exhibits dopamine receptor binding activity and phosphatase binding activity. Involved in several processes, including dopamine receptor signaling pathway; negative regulation of signal transduction; and organic anion transport. Localizes to several cellular components, including the brush border membrane; sperm midpiece; and stereocilium tip. Human ortholog(s) of this gene implicated in hypophosphatemic nephrolithiasis/osteoporosis 2. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; pleura; and sensory organ. Orthologous to human SLC9A3R1 (SLC9A3 regulator 1); PARTICIPATES IN eicosanoid signaling pathway; parathyroid hormone signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 1,2-dibromoethane; 1,4-dioxane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EBP-50; EBP50; ezrin-radixin-moesin-binding phosphoprotein 50; MGC95776; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; NHE-RF; NHERF-1; NHERF1; regulatory cofactor of Na(+)/H(+) exchanger; sodium-hydrogen exchanger regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1; solute carrier family 9 isoform A3 regulatory factor 1
Homo sapiens (human) : SLC9A3R1 (SLC9A3 regulator 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc9a3r1 (SLC9A3 regulator 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc9a3r1 (SLC9A3 regulator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC9A3R1 (SLC9A3 regulator 1)
Canis lupus familiaris (dog) : SLC9A3R1 (SLC9A3 regulator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc9a3r1 (SLC9A3 regulator 1)
Sus scrofa (pig) : SLC9A3R1 (SLC9A3 regulator 1)
Chlorocebus sabaeus (green monkey) : SLC9A3R1 (SLC9A3 regulator 1)
Heterocephalus glaber (naked mole-rat) : Slc9a3r1 (SLC9A3 regulator 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl11115,163,341 - 115,181,181 (+)Ensembl
GRCm3811115,163,341 - 115,181,178 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711115,024,655 - 115,042,492 (+)NCBIGRCm37mm9NCBIm37
MGSCv3611114,979,493 - 115,014,684 (+)NCBImm8
Celera11126,928,560 - 126,946,416 (+)NCBICelera
Cytogenetic Map11 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Slc9a3r1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732281
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.