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Gene: SLC9A3R1 (SLC9A3 regulator 1) Homo sapiens
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Symbol: SLC9A3R1
Name: SLC9A3 regulator 1
Description: Exhibits several functions, including PDZ domain binding activity; beta-catenin binding activity; and signaling receptor binding activity. Involved in several processes, including establishment of Golgi localization; regulation of signal transduction; and renal phosphate ion absorption. Localizes to the apical plasma membrane; microvillus; and perinuclear region of cytoplasm. Implicated in hypophosphatemic nephrolithiasis/osteoporosis 2.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EBP50; ezrin-radixin-moesin binding phosphoprotein-50; ezrin-radixin-moesin-binding phosphoprotein 50; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Na+/H+ exchange regulatory co-factor; NHERF; NHERF-1; NHERF1; NPHLOP2; regulatory cofactor of Na(+)/H(+) exchanger; sodium-hydrogen exchanger regulatory factor 1; sodium/hydrogen exchanger regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1; solute carrier family 9 isoform A3 regulatory factor 1; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
Orthologs:
Mus musculus (house mouse) : Slc9a3r1 (solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc9a3r1 (SLC9A3 regulator 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc9a3r1 (SLC9A3 regulator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC9A3R1 (SLC9A3 regulator 1)
Canis lupus familiaris (dog) : SLC9A3R1 (SLC9A3 regulator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc9a3r1 (SLC9A3 regulator 1)
Sus scrofa (pig) : SLC9A3R1 (SLC9A3 regulator 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381774,748,628 - 74,769,353 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371772,744,751 - 72,765,499 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361770,256,373 - 70,277,089 (+)NCBINCBI36hg18NCBI36
Build 341770,256,378 - 70,277,089NCBI
Celera1769,337,944 - 69,358,679 (+)NCBI
Cytogenetic Map17q25.1NCBI
HuRef1768,155,124 - 68,175,866 (+)NCBIHuRef
CHM1_11772,809,571 - 72,830,338 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC9A3R1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1342625
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.