Cia28 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Cia28 (Collagen induced arthritis QTL 28) Rattus norvegicus

Symbol: Cia28
Name: Collagen induced arthritis QTL 28
RGD ID: 1576307
Previously known as: Cia5a
Trait: joint integrity trait   (VT:0010548)    
Measurement Type: joint inflammation composite score   (CMO:0000919)    
LOD Score: Not Available
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21096,120,911 - 104,060,283RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01099,492,217 - 107,857,673RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01099,184,058 - 107,484,761RGDRnor5.0
RGSC_v3.410100,633,512 - 110,718,848RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.110100,648,024 - 110,733,352RGD
Cross Type: Not Available
Strains Crossed: DA.F344-(D10Rat204-D10Arb22)/Arb 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Cia28Ratjoint inflammation composite score  IDA 1359065 RGD 

Experimental Condition
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Cia28RatFreund's incomplete adjuvant  IDA 1359065 RGD 
Cia28Rattype II collagen  IDA 1359065 RGD 

Measurement Method
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Cia28Ratin vivo visual assessment  IDA 1359065 RGD 

Rat Strain
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Cia28RatDA.F344-(D10Rat204-D10Arb22)/Arb  IEA 1359065 RGD 

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
Cia28Ratjoint integrity trait  IDA 1359065 RGD 

Disease Annotations     Click to see Annotation Detail View

Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. The non-MHC quantitative trait locus Cia5 contains three major arthritis genes that differentially regulate disease severity, pannus formation, and joint damage in collagen- and pristane-induced arthritis. Brenner M, etal., J Immunol 2005 Jun 15;174(12):7894-903.
2. Genetic regulation of T regulatory, CD4, and CD8 cell numbers by the arthritis severity loci Cia5a, Cia5d, and the MHC/Cia1 in the rat. Brenner M, etal., Mol Med. 2007 May-Jun;13(5-6):277-87.
3. The complexity in hunting for candidate genes within QTL that determine susceptibility to arthritis in rats. Xiong Q, etal., Crit Rev Immunol. 2008;28(2):127-57.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
11396194LOC108352153uncharacterized LOC108352153109631197996366541Rat
11358786LOC108352154uncharacterized LOC108352154109636815996380190Rat
2323140Fcf1-ps2Fcf1 rRNA-processing protein, pseudogene 2109670907896709724Rat
1565086Ube2c-ps1ubiquitin-conjugating enzyme E2C, pseudogene 1109707829097079160Rat
41145218LOC120095207uncharacterized LOC120095207109717843497201392Rat
41357600LOC120095209uncharacterized LOC120095209109745199197464219Rat
7737388LOC102547123uncharacterized LOC102547123109763351897648796Rat
11422283LOC108352188high mobility group protein B3 pseudogene109765561197657071Rat
9136714LOC103693474uncharacterized LOC103693474109775472397756670Rat
620474Sox9SRY-box transcription factor 9109780648597811994Rat
7566917LOC102549521uncharacterized LOC102549521109801374198022561Rat
7611149LOC102549596uncharacterized LOC102549596109804971498085007Rat
7734651LOC102549836uncharacterized LOC102549836109807489798232243Rat
11366916LOC108352157uncharacterized LOC108352157109813640098152364Rat
9685629Mir297microRNA 297109821647998216544Rat
1311981Slc39a11solute carrier family 39, member 11109827595898697042Rat
41378255LOC120095210uncharacterized LOC120095210109839472598400326Rat
41106371Trnaa-ugc10transfer RNA alanine (anticodon UGC) 10109848991898489992Rat
3763Sstr2somatostatin receptor 2109866420498671370Rat
1304594Cog1component of oligomeric golgi complex 1109869548198708495Rat
1563409Vcf1VCP nuclear cofactor family member 1109870740498728486Rat
1359207Mtnap1mitochondrial nucleoid associated protein 1109872866198738693Rat
1306397Cpsf4lcleavage and polyadenylation specific factor 4-like109874181698756069Rat
1311567Cdc42ep4CDC42 effector protein 4109877261398797924Rat
1310397Sdk2sidekick cell adhesion molecule 2109882491699102590Rat
7689502LOC102547853uncharacterized LOC102547853109890697998941230Rat
7593118LOC102547687uncharacterized LOC102547687109906304999071550Rat
41006281LOC120095211uncharacterized LOC120095211109912871999139667Rat
7658394LOC102548022uncharacterized LOC102548022109923331399267271Rat
40948865LOC120095337uncharacterized LOC120095337109930475999312501Rat
41116026LOC120095212uncharacterized LOC120095212109937129899400738Rat
1305573Rpl38ribosomal protein L38109970133099705004Rat
1562969Ttyh2tweety family member 2109970906399753449Rat
1359602Dnai2dynein, axonemal, intermediate chain 2109975996699793379Rat
41400420LOC120095402small nucleolar RNA SNORA67109977276499772893Rat
1559936Kif19kinesin family member 19109980018599826546Rat
1563331Btbd17BTB domain containing 17109982613299832624Rat
1559926Gpr142G protein-coupled receptor 142109984006999843410Rat
1311408Gprc5cG protein-coupled receptor, class C, group 5, member C109988690099908928Rat
1583719Cd300aCd300a molecule109992980199942674Rat
1583718Cd300lbCD300 molecule-like family member b109996480199974790Rat
1559458CD300c-ps1CD300c molecule, pseudogene 110100004943100010110Rat
1562156Cd300ldl1Cd300 molecule-like family member D like 110100056712100078276Rat
2319739Cd300ldCd300 molecule-like family member D10100082957100115853Rat
6502330Cd300cl1CD300c molecule like 110100117788100126304Rat
1562667Cd300c2l1CD300C molecule 2 like 110100136144100140607Rat
41394609Slc25a5-ps13solute carrier family 25 member 5, pseudogene 1310100153609100154533Rat
1592119Igsf7immunoglobulin superfamily, member 710100153767100161589Rat
1564512Slc25a5-ps5solute carrier family 25 member 5, pseudogene 510100174797100175737Rat
1559482Igsf7l1immunoglobulin superfamily, member 7 like 110100174955100182713Rat
9443602Cd300ld-ps1Cd300 molecule-like family member D, pseudogene 110100188157100192555Rat
1563057CD300c-ps2CD300c molecule, pseudogene 210100198793100203759Rat
1565161Cd300cCD300c molecule10100228254100233207Rat
1561778Cd300c2CD300C molecule 210100253312100258553Rat
1586269Slc25a5-ps8solute carrier family 25 member 5, pseudogene 810100260249100261714Rat
1305426Cd300leCd300 molecule-like family member E10100271076100280400Rat
1585137Cd300eCd300e molecule10100289729100309996Rat
1586145Rpl6-ps9ribosomal protein L6, pseudogene 910100299625100302548Rat
9228340LOC103693477uncharacterized LOC10369347710100312410100321685Rat
41341585Trnaa-agc73transfer RNA alanine (anticodon AGC) 7310100332749100332832Rat
2319982Rab37RAB37, member RAS oncogene family10100334639100401974Rat
1309733Cd300lfCd300 molecule-like family member F10100359942100376130Rat
708538Nherf1NHERF family PDZ scaffold protein 110100403189100420290Rat
1307096Nat9N-acetyltransferase 910100422326100427510Rat
1307953Tmem104transmembrane protein 10410100427244100485890Rat
2739Grin2cglutamate ionotropic receptor NMDA type subunit 2C10100488430100507083Rat
621648Fdxrferredoxin reductase10100507863100516649Rat
1311950Fads6fatty acid desaturase 610100522981100538181Rat
1304551Ush1gUSH1 protein network component sans10100559721100563590Rat
1304830Otop2otopetrin 210100564727100574298Rat
1306663Otop3otopetrin 310100577346100588729Rat
1311422Hid1HID1 domain containing10100589555100610050Rat
1306881Cdr2lcerebellar degeneration-related protein 2-like10100625150100638669Rat
1307942Mrpl58mitochondrial ribosomal protein L5810100646374100652871Rat
11407049Trnar-ccu7transfer RNA arginine (anticodon CCU) 710100654877100654949Rat
11507218Trnar-ccu8transfer RNA arginine (anticodon CCU) 810100655228100655300Rat
11494208Trnar-ucg2transfer RNA arginine (anticodon UCG) 210100655695100655767Rat
620083Atp5pdATP synthase peripheral stalk subunit d10100657700100662960Rat
1566063Kctd2potassium channel tetramerization domain containing 210100663013100674756Rat
1311352Trim80tripartite motif protein 8010100682826100691152Rat
1582896Slc16a5solute carrier family 16 member 510100707434100721338Rat
1310043Armc7armadillo repeat containing 710100723080100739636Rat
2321875Nt5c5', 3'-nucleotidase, cytosolic10100739591100742276Rat
1359325Jpt1Jupiter microtubule associated homolog 110100744468100762504Rat
41132968LOC120093044small nucleolar RNA SNORA1910100770794100770925Rat
621761Sumo2small ubiquitin-like modifier 210100771941100784503Rat
40961797Ftl1-ps10ferritin light chain 1, pseudogene 1010100802981100803581Rat
1311942Nup85nucleoporin 8510100806482100825029Rat
1309553Gga3golgi associated, gamma adaptin ear containing, ARF binding protein 310100825427100843422Rat
41126172LOC120095367U6 spliceosomal RNA10100841109100841219Rat
1309164Mrps7mitochondrial ribosomal protein S710100843691100846838Rat
1309685Mif4gdMIF4G domain containing10100847168100852166Rat
1359554Slc25a19solute carrier family 25 member 1910100853554100867517Rat
619758Grb2growth factor receptor bound protein 210100881404100949193Rat
41119811LOC120095390small nucleolar RNA SNORA7010100964850100964982Rat
41200060LOC120095355U6 spliceosomal RNA10100984804100984906Rat
7685108Tmem94transmembrane protein 9410100991523101027046Rat
41070056Dppa2l-ps3developmental pluripotency-associated 2 like, pseudogene 310100994741100999028Rat
4888579Mir3577microRNA 357710101023869101023981Rat
1309738Caskin2cask-interacting protein 210101027196101041429Rat
1597379Tsen54tRNA splicing endonuclease subunit 5410101041607101050088Rat
1560307Llgl2LLGL scribble cell polarity complex component 210101050978101086527Rat
1597365Myo15bmyosin XVB10101088734101126159Rat
1310823Recql5RecQ like helicase 510101126544101165739Rat
1586374Smim5small integral membrane protein 510101134033101139814Rat
7720946Erlnendoregulin10101144577101147160Rat
1565537Sap30bpSAP30 binding protein10101165777101198503Rat
2321678Rps18l1ribosomal protein S18-like 110101204519101205067Rat
2928Itgb4integrin subunit beta 410101206657101243012Rat
1305375Galk1galactokinase 110101243146101247323Rat
621095H3f3bH3.3 histone B10101256484101258716Rat
1309224Unkunk zinc finger10101265732101295950Rat
628593Unc13dunc-13 homolog D10101296755101311513Rat
620032Wbp2WW domain binding protein 210101312476101320775Rat
7503996LOC102552044uncharacterized LOC10255204410101320917101341100Rat
1597317Trim47tripartite motif-containing 4710101337573101342044Rat
40942668LOC120093105uncharacterized LOC12009310510101343364101364468Rat
1559497Trim65tripartite motif-containing 6510101357937101364036Rat
1311180Mrpl38mitochondrial ribosomal protein L3810101365353101372159Rat
1310662Fbf1Fas binding factor 110101375769101401624Rat
619757Acox1acyl-CoA oxidase 110101406197101431252Rat
1311078Ten1TEN1 subunit of CST complex10101431328101455105Rat
1306141Evplenvoplakin10101458227101474778Rat
1305376Srp68signal recognition particle 6810101481213101508035Rat
41131801LOC120095213uncharacterized LOC12009521310101490110101491580Rat
2657Galr2galanin receptor 210101513689101517176Rat
620236Exoc7exocyst complex component 710101521630101540425Rat
621764Foxj1forkhead box J110101566299101570370Rat
11506243LOC108352160uncharacterized LOC10835216010101571155101586495Rat
1591154Rnf157ring finger protein 15710101571972101639874Rat
1311298Ubald2UBA-like domain containing 210101662507101667089Rat
1562974Qrich2glutamine rich 210101669240101697643Rat
620206Prpsap1phosphoribosyl pyrophosphate synthetase-associated protein 110101701094101750753Rat
10412358Khps1asphk1a antisense transcript10101758466101759755Rat
620048Sphk1sphingosine kinase 110101758567101764240Rat
1310297Ube2oubiquitin-conjugating enzyme E2O10101765572101812736Rat
41380343LOC120095357U6 spliceosomal RNA10101808139101808246Rat
1559519Rpl14-ps1ribosomal protein L14, pseudogene 110101823987101824649Rat
2006Aanataralkylamine N-acetyltransferase10101827072101831805Rat
1309699Rhbdf2rhomboid 5 homolog 210101833157101860283Rat
69415Cygbcytoglobin10101877675101887442Rat
6488422Prcdphotoreceptor disc component10101887192101907647Rat
41259286Snord1csmall nucleolar RNA, C/D box 1C10101905797101905872Rat
41268363LOC120095397small nucleolar RNA R3810101907729101907804Rat
11391163LOC108352161uncharacterized LOC10835216110101907879101909302Rat
1560747St6galnac2ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 210101910220101928412Rat
1562048St6galnac1ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 110101972656101983053Rat
1594666Mxra7matrix remodeling associated 710102003034102031428Rat
1305395Jmjd6jumonji domain containing 6, arginine demethylase and lysine hydroxylase10102041131102047182Rat
1306284Mettl23methyltransferase 23, arginine10102047090102053379Rat
1359422Srsf2serine and arginine rich splicing factor 210102052158102055365Rat
1307394Mfsd11major facilitator superfamily domain containing 1110102055516102075064Rat
1305188Mgat5balpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B10102120757102190235Rat
6489294LOC100912002uncharacterized LOC10091200210102275964102278092Rat
41249041Scarna16small Cajal body-specific RNA 1610102276365102276548Rat
1563123Sec14l1SEC14-like lipid binding 110102319920102367070Rat
40973997Rpl12-ps9ribosomal protein L12, pseudogene 910102335984102342705Rat
7606875LOC102547461uncharacterized LOC10254746110102365521102371047Rat
708523Septin9septin 910102409798102579056Rat
40962635LOC120095338uncharacterized LOC12009533810102679056102679709Rat
41339413LOC120095215uncharacterized LOC12009521510102700854102711178Rat
41047789LOC120095216uncharacterized LOC12009521610102709185102716649Rat
40962029LOC120095218uncharacterized LOC12009521810102722060102756134Rat
41374005LOC120095217uncharacterized LOC12009521710102722625102723996Rat
7555371LOC102546977uncharacterized LOC10254697710102767337102772610Rat
6487731LOC100912319uncharacterized LOC10091231910102797707102845427Rat
1310027Tnrc6ctrinucleotide repeat containing adaptor 6C10102908958102979543Rat
1591146Tmc6transmembrane channel like 610102982059102999509Rat
1591150Tmc8transmembrane channel-like 810103000038103010601Rat
1591144C10h17orf99smilar to human chromosome 17 open reading frame 9910103015371103027407Rat
41212192LOC120095354U6 spliceosomal RNA10103024725103024828Rat
621334Syngr2synaptogyrin 210103029903103034473Rat
621014Tk1thymidine kinase 110103034755103046125Rat
1591143Afmidarylformamidase10103046129103061718Rat
7539496LOC102548046uncharacterized LOC10254804610103055865103057531Rat
70499Birc5baculoviral IAP repeat-containing 510103072530103081382Rat
1591141Tmem235transmembrane protein 23510103081716103092187Rat
1591140Tha1threonine aldolase 110103094681103100169Rat
41243579LOC120095219uncharacterized LOC12009521910103113533103115901Rat
41242416LOC120095220uncharacterized LOC12009522010103115944103119116Rat
41366572LOC120095340uncharacterized LOC12009534010103119236103123667Rat
621087Socs3suppressor of cytokine signaling 310103193909103197322Rat
1305052Pgs1phosphatidylglycerophosphate synthase 110103214635103250254Rat
1563805Dnah17dynein, axonemal, heavy chain 1710103244144103364953Rat
41163197LOC120095221uncharacterized LOC12009522110103262366103264333Rat
620397Cyth1cytohesin 110103402727103485826Rat
1309937Usp36ubiquitin specific peptidase 3610103497349103528877Rat
61312Timp2TIMP metallopeptidase inhibitor 210103541199103590611Rat
1597046Cep295nlCEP295 N-terminal like10103562190103581183Rat
620837Lgals3bpgalectin 3 binding protein10103619912103629251Rat
628743Cant1calcium activated nucleotidase 110103637079103650240Rat
7683659LOC102548791uncharacterized LOC10254879110103655144103658176Rat
1359204C1qtnf1C1q and TNF related 110103660319103681662Rat
1310868Engaseendo-beta-N-acetylglucosaminidase10103707169103719833Rat
1560070Rbfox3RNA binding fox-1 homolog 310103720355104157277Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34202D10Mgh1613410102359683102359817Ratregion
35256D10Rat11191109612091196121100Ratregion
35364D10Rat614610101435864101436010Ratregion
35386D10Rat8157109940697199407128Ratregion
36494D10Rat517210103349037103349209Ratregion
34941D10Rat717310101012337101012510Ratregion
35665D10Rat415610102134116102134272Ratregion
40488D10Rat201162109827943498279596Ratregion
38542D10Rat132238109670304396703281Ratregion
40070D10Rat188130109672505096725180Ratregion
38844D10Rat101211109821135998211570Ratregion
39358D10Rat88211109802573698025938Ratregion
41382D10Rat136166109789809697898372Ratregion
41382D10Rat136166109789820697898372Ratregion
42935D10Rat232197109662147796621674Ratregion
42936D10Rat231237109855410198554338Ratregion
42937D10Rat229209109888103598881244Ratregion
42938D10Rat228115109902101699021131Ratregion
42939D10Rat268158109952612899526290Ratregion
42940D10Rat227238109938417899384416Ratregion
42373D10Rat267129109677281196772940Ratregion
41042D10Rat13420710103784905103785112Ratregion
41860D10Rat230208109833495198335153Ratregion
44836D10Got154107109701014797010254Ratregion
44837D10Got152142109773056397730705Ratregion
44837D10Got152142109773056397730821Ratregion
44838D10Got153111109645978696459897Ratregion
44839D10Wox7115109895262698952741Ratregion
44840D10Got156154109924882999248983Ratregion
44841D10Got15820610100308669100308873Ratregion
59973D10Got15517110100299840100300011Ratregion
59974D10Got15713010100604759100604889Ratregion
61275D10Arb2215010104060133104060283Ratregion
66415D10Mco44255109792435797924612Ratregion
66520D10Mco70260109683600696836268Ratregion
66521D10Mco71261109908049599080758Ratregion
66563D10Mco6186109800301998003205Ratregion
1630499D10Wox5227410101827515101827789Ratregion
1578893D10Chm84250109797137297971624Ratregion
1578908D10Chm83177109762834897628527Ratregion
1579012D10Chm86246109758650797586753Ratregion
1579089D10Chm82205109764399997644206Ratregion
1626942Galr223010101514753101514983Ratregion
1626975Aanat23010101831462101831692Ratregion
1627187Srp6817910101481406101481585Ratregion
1628621D10Wox3218610104060093104060279Ratregion
1632738D10Got24917410100278016100278190Ratregion
1635021D10Cebr220010101545465101545665Ratregion
1635341D10Got219179109978608799786266Ratregion
7192936Sox9396109778676197787157Ratregion
7193029Sox90109780822597809532Ratregion
7191222D10MIT11213109730789597308109Ratregion
5038788RH127333218109870743698707654Ratregion
5036161D11Bwg0554e21210103637078103637290Ratregion
5036169D11Wsu175e22410102052252102052476Ratregion
5038992RH12745018810101910284101910472Ratregion
5036462Ppicap21810103620024103620242Ratregion
5039056RH127487193109975324099753433Ratregion
5039084RH12750318410101365444101365628Ratregion
5036869AU04946514810101572087101572235Ratregion
5036877AU04948927710100438726100439003Ratregion
5036949AU049721264109700996897010232Ratregion
5037117D4S2570E10710102055017102055124Ratregion
5031342PMC148819P151310103195568103196081Ratregion
7205792RH4709611110101257662101257861Ratregion
7206096Timp213010103590354103590484Ratregion
7206098Ddc841510103568065103568480Ratregion
7206100Timp210710103553466103553573Ratregion
7206102Timp210510103556030103556135Ratregion
7206104Timp212010103545903103546023Ratregion
7206106Timp217210103543868103544040Ratregion
5028725AFMa071ze921910101802958101803177Ratregion
5031494AU048139145109846648698466631Ratregion
5034173RH14164621510102275350102275565Ratregion
5031816AU047058180109684101696841196Ratregion
5026472RH132341189109996279899962987Ratregion
5026492RH13241920010100488625100488825Ratregion
5026734RH13333218310101877700101877883Ratregion
5032036AU02895214210103121575103121717Ratregion
5032299AV220920120109781023597810355Ratregion
5035082Cda0wb1114710100824847100824994Ratregion
5026970RH13422820010101198267101198467Ratregion
5032753RH13517520410100742847100743051Ratregion
5025244RH12757019010100847211100847401Ratregion
5025274RH12768821410101701122101701336Ratregion
5030425BF397540187109768370897683895Ratregion
5028123D11Mit10215210101826812101826964Ratregion
5025628RH12904918010103681377103681557Ratregion
5025780RH129637150109994289199943041Ratregion
5053611RH14274915310100853609100853762Ratregion
5051731RH9462516210101242819101242981Ratregion
5056569RH144454297109882793498828231Ratregion
5057063D7Arb609a967109830246798303434Ratregion
5056501RH14441523210100589776100590008Ratregion
5056501RH14441523210100589776100590008Ratregion
5055637RH14391610510101341842101341947Ratregion
5049848RH133716192109870725398708433Ratregion
5050034RH13382419310100882910100883103Ratregion
5050128RH13387820710101307291101307498Ratregion
5050968RH13436218910103250012103250201Ratregion
5050154RH13389321510103542146103542361Ratregion
5053013RH14240416610101196330101196496Ratregion
5053153RH14248412110101164535101164656Ratregion
5043410RH130010199109877269298772891Ratregion
5043592RH13011322010102009405102010773Ratregion
5041400RH12883519310100310416100310609Ratregion
5046106RH13156118010101516894101517074Ratregion
5044616RH130706150109990550899905658Ratregion
5048688RH13304821710103637140103637357Ratregion
5044382RH13057018010101764046101764226Ratregion
5044900RH13086819810101242714101242912Ratregion
5045098RH13098218010101049740101049920Ratregion
5048838RH13313522010103347056103347276Ratregion
5045874RH13142820110102041227102041428Ratregion
5049138RH13330736710102051347102051714Ratregion
5049124RH13329919610102074320102074516Ratregion
5046836RH13198221110101358040101358251Ratregion
5046868RH13200119810101026820101027018Ratregion
5048018RH13266118410100485562100485746Ratregion
5048142RH13273218010101295574101295754Ratregion
5049332RH13342020310101312455101312658Ratregion
5049464RH133496220109807585898076078Ratregion
5047252RH13222119610102805250102805446Ratregion
5047386RH13229720110103055929103057382Ratregion
5048350RH13285220210100401733100401935Ratregion
5048432RH13290020310102979127102979330Ratregion
5042466RH12945120110102003070102003271Ratregion
5048516RH132948181109926391999264100Ratregion
5042776RH129639193109994267699942869Ratregion
5042812RH12966018010100739629100739809Ratregion
5040632RH12839419010101126624101126814Ratregion
5040116RH12809819310100657809100659111Ratregion
5041162RH12869818010103541216103541396Ratregion
5043764RH130214181109870910098709281Ratregion
5042890RH12970618310102006688102006871Ratregion
5041322RH12879018410101406255101406439Ratregion
5075420RH138583146109818524198185387Ratregion
5079684RH14114318910101086237101086426Ratregion
5077260RH13965421610102051833102052049Ratregion
5077980RH14007220010101521253101521453Ratregion
5078426RH14033617110100596161100596332Ratregion
5078592RH140433797109873597798736774Ratregion
5070754RH13468521010101458302101458512Ratregion
5070800RH134713201109781174097811941Ratregion
5072948RH13714619710101337739101337936Ratregion
5080310RH141506180109845625398456433Ratregion
5072958RH137152189109877274498772933Ratregion
5073960RH137738146109982623599826381Ratregion
5073258RH13733221210101196214101196426Ratregion
5071454RH13509121510100854515100854730Ratregion
5071546RH13514518310102632184102632367Ratregion
5072204RH13671314410100821969100822113Ratregion
5074772RH13820916610103498793103498959Ratregion
5071902RH13535120410101574034101574238Ratregion
5067086AU04797316710102378945102379112Ratregion
5067098AU047965246109866523698665482Ratregion
5067216AU04789115010102235509102235659Ratregion
5067226AU04788525910102999096102999355Ratregion
5067228AU04788414510101240329101240474Ratregion
5067434AU047748130109730787097308000Ratregion
5067556AU04767415810102676230102676388Ratregion
5067794AU04753229710102019712102020006Ratregion
5067794AU04753229710102019712102020095Ratregion
5068302AU047226174109971240499712880Ratregion
5070257RH9456319210100488555100488747Ratregion
5066060BE116687156109806103098061186Ratregion
5066304PMC148819P213710103195944103196081Ratregion
5087903Grin2c17910100488917100489096Ratregion
5087472PMC199556P19010101412196101412286Ratregion
5087504PMC21059P263510101406415101407050Ratregion
5088116Sox9207109780926897809475Ratregion
5089615AU049260123109909855599098677Ratregion
5087580PMC34415P1297109780679897807095Ratregion
5085070Foxj126110101567503101567764Ratregion
5088659AU04870017610100299865100300041Ratregion
5090013AU049498216109774712497747338Ratregion
5080844RH14181566010100422577100423237Ratregion
5081282RH142070200109871971098719910Ratregion
5084746AI22853024910103835819103836072Ratregion
5085776BQ211419153109807496098075113Ratregion
5503885SSTR2404109866993598670339Ratregion
5505338Jmjd6140810102043461102044869Ratregion
5505526D2S147115310103878082103879235Ratregion
5506433UniSTS:47926583410102054314102055148Ratregion
5507049UniSTS:22418015810101256889101257047Ratregion
5506971fc37g07.x10109827953898280010Ratregion
5500103UniSTS:23677925510101196123101196378Ratregion
5501245PMC165604P183810103007528103008366Ratregion
5504736PMC86057P126810103036286103036632Ratregion
5504793UniSTS:27563574410102052885102053630Ratregion
Position Markers

Flank 1: (D10Rat11)
Rat AssemblyChrPosition (strand)Source
GRCr81096,620,293 - 96,620,484 (+)Marker Load Pipeline
mRatBN7.21096,120,911 - 96,121,100 (+)MAPPER
Rnor_6.01099,492,217 - 99,492,409NCBI
Rnor_5.01099,184,058 - 99,184,250UniSTS
RGSC_v3.410100,633,654 - 100,633,848UniSTS
RGSC_v3.410100,633,512 - 100,633,982RGD
RGSC_v3.110100,648,024 - 100,648,218RGD
Celera1094,766,403 - 94,766,596UniSTS
RH 3.4 Map101084.8RGD
RH 3.4 Map101084.8UniSTS
RH 2.0 Map101218.2RGD
SHRSP x BN Map1077.15RGD
FHH x ACI Map1082.4RGD
Flank 2: (D10Arb22)
Rat AssemblyChrPosition (strand)Source
mRatBN7.210104,060,133 - 104,060,283 (+)MAPPER
Rnor_6.010107,857,524 - 107,857,673NCBI
Rnor_5.010107,484,612 - 107,484,761UniSTS
Celera10102,615,292 - 102,615,441UniSTS
Cytogenetic Map10q32.3UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093223816107057807Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
631558Bp137Blood pressure QTL 1370.013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)109472486096836268Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
1579915Bp280Blood pressure QTL 2800.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090404397107211142Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1072224939107211142Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076452683107211142Rat
1300107Rf18Renal function QTL 183.41urine output (VT:0003620)timed urine volume (CMO:0000260)107877551698279596Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1082685200107211142Rat
70168Eae12Experimental allergic encephalomyelitis QTL 120.0009nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1092238497101012337Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
2313856Bp342Blood pressure QTL 3424.40.0001life span trait (VT:0005372)age at time of death (CMO:0001193)108730761796121100Rat
1578672Bmd16Bone mineral density QTL 166.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)1096703043107057807Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2292617Ept18Estrogen-induced pituitary tumorigenesis QTL 183.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107345313696120911Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1069738412107211142Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1069738412107211142Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072224939107211142Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087307617107211142Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106674365598003205Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106134527698211570Rat
724530Bp149Blood pressure QTL 1490.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090627439107211142Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1090627439107057807Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1069738412107211142Rat
1578663Bss18Bone structure and strength QTL 183.6femur width (VT:1000666)femoral neck width (CMO:0001695)1096703043107057807Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1064890616107211142Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
6893357Bw102Body weight QTL 1020.50.36body mass (VT:0001259)body weight (CMO:0000012)1080515287101325465Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)90404397107211142Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)90404397107211142Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1090404397107211142Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1090404397107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
12880395Cm109Cardiac mass QTL 1090.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1090404397107211142Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068420376107211142Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1088539139107211142Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1076748906107211142Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070199100107211142Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
1576313Pia25Pristane induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096120911104060283Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)106134527699703528Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1576307Cia28Collagen induced arthritis QTL 28joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096120911104060283Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)106134527699703528Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1076246085107211142Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1085565469103884409Rat
1358188Ept9Estrogen-induced pituitary tumorigenesis QTL 93.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107345313696120911Rat
631539Oia6Oil induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1097010147104670812Rat
631538Oia5Oil induced arthritis QTL 5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087055121107211142Rat
61436Cia5Collagen induced arthritis QTL 54.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1091228102104060283Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068383129107211142Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_gene 223 known and 36 novel genes were found in an analysis based on PubMed and OMIM data 2307198
qtl_statistics_details region gave protection from CIA and PIA 1359065