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Gene: Serpinf2 (serpin family F member 2) Rattus norvegicus
Symbol: Serpinf2
Name: serpin family F member 2
Description: Exhibits serine-type endopeptidase inhibitor activity. Involved in negative regulation of fibrinolysis and response to organic substance. Localizes to extracellular space. Biomarker of familial hyperlipidemia. Human ortholog(s) of this gene implicated in alpha-2-plasmin inhibitor deficiency. Orthologous to human SERPINF2 (serpin family F member 2); PARTICIPATES IN fibrinolysis pathway; coagulation cascade pathway; complement system pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
Also known as: alpha-2-antiplasmin; LOC287527; serine (or cysteine) peptidase inhibitor, clade F, member 2; serine (or cysteine) proteinase inhibitor, clade F, member 2; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
Homo sapiens (human) : SERPINF2 (serpin family F member 2)  HGNC  Alliance
Mus musculus (house mouse) : Serpinf2 (serine (or cysteine) peptidase inhibitor, clade F, member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpinf2 (serpin family F member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINF2 (serpin family F member 2)
Canis lupus familiaris (dog) : SERPINF2 (serpin family F member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpinf2 (serpin family F member 2)
Sus scrofa (pig) : SERPINF2 (serpin family F member 2)
Chlorocebus sabaeus (African green monkey) : SERPINF2 (serpin family F member 2)
Heterocephalus glaber (naked mole-rat) : Serpinf2 (serpin family F member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01062,264,247 - 62,272,353 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,264,788 - 62,273,119 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,978,965 - 61,987,194 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,748,116 - 62,756,200 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11062,761,738 - 62,769,823 (-)NCBI
Celera1059,300,854 - 59,308,938 (-)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Serpinf2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306692
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.