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Gene: Cltc (clathrin heavy chain) Rattus norvegicus
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Symbol: Cltc
Name: clathrin heavy chain
Description: Exhibits several functions, including ankyrin binding activity; heat shock protein binding activity; and protein C-terminus binding activity. Involved in Golgi organization; endocytosis; and mitotic cell cycle. Localizes to the T-tubule; cytoplasm; and spindle. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 56. Orthologous to human CLTC (clathrin heavy chain); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; FasL mediated signaling pathway; endocytosis pathway; INTERACTS WITH 2,4-dinitrotoluene; 2-ethoxyethanol; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: clathrin heavy chain 1; clathrin, heavy chain (Hc); clathrin, heavy polypeptide (Hc)
Orthologs:
Homo sapiens (human) : CLTC (clathrin heavy chain)  HGNC  Alliance
Mus musculus (house mouse) : Cltc (clathrin, heavy polypeptide (Hc))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cltc (clathrin heavy chain)
Pan paniscus (bonobo/pygmy chimpanzee) : CLTC (clathrin heavy chain)
Canis lupus familiaris (dog) : CLTC (clathrin heavy chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cltc (clathrin heavy chain)
Sus scrofa (pig) : CLTC (clathrin heavy chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01074,014,560 - 74,070,578 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01076,029,919 - 76,085,924 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41074,976,825 - 75,032,529 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11074,991,194 - 75,046,899 (-)NCBI
Celera1070,438,273 - 70,493,354 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cltc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2364
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.