Hcuc4 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Hcuc4 (Hepatic copper content QTL 4) Rattus norvegicus

Symbol: Hcuc4
Name: Hepatic copper content QTL 4
RGD ID: 631565
Trait: liver copper amount   (VT:0003065)    
Measurement Type: liver copper weight to liver dry weight ratio   (CMO:0001512)    
LOD Score: 4.15
P Value: Not Available
Variance: Not Available
Inheritance Type: recessive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81067,439,473 - 73,950,209RGD_MAPPER_PIPELINE
mRatBN7.21066,941,813 - 73,452,992RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01069,348,459 - 75,983,662RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01068,983,854 - 74,127,825RGDRnor5.0
RGSC_v3.41070,191,595 - 77,091,834RGDRGSC3.4
RGSC_v3.11070,205,218 - 77,106,262RGD
Cross Type: Not Available
Strains Crossed: BC/CpbU LEW/OlaHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Atox1 is a candidate Gene for Hcuc4


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hcuc4Ratliver disease  IAGP 629572 RGD 
Hcuc4RatWilson disease  IAGP 629572 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hcuc4Ratincreased liver copper level  QTM 629572 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hcuc4Ratliver copper weight to liver dry weight ratio  IDA 629572 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hcuc4Ratcontrolled cholesterol content diet  IDA 629572 RGD 
Hcuc4Ratcontrolled olive oil content diet  IDA 629572 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hcuc4Ratflame atomic absorption spectrometry  IDA 629572 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hcuc4RatBC/CpbU  IEA 629572 RGD 
Hcuc4RatLEW/OlaHsd  IEA 629572 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Hcuc4Ratliver copper amount  IDA 629572 RGD 


#
Reference Title
Reference Citation
1. Quantitative trait loci influencing hepatic copper in rats. de Wolf ID, etal., Exp Biol Med (Maywood) 2002 Jul;227(7):529-34.

Related QTL Description Reference
Hcuc1 maps to same region RGD:629572



1 to 20 of 154 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
11435226LOC108352208uncharacterized LOC108352208106694046266956291Rat
3645Ccl2C-C motif chemokine ligand 2106700542467007222Rat
1359152Ccl7C-C motif chemokine ligand 7106701644667018296Rat
3644Ccl11C-C motif chemokine ligand 11106702832867032929Rat
1309255Ccl12C-C motif chemokine ligand 12106707023067071780Rat
1586495Ccl1C-C motif chemokine ligand 1106712833167131109Rat
1565522Tmem132etransmembrane protein 132E106733086367386790Rat
41176308LOC120095155uncharacterized LOC120095155106750811867610797Rat
1359453Cct6bchaperonin containing TCP1 subunit 6B106765246167701385Rat
11472642LOC108352113transcription factor BTF3 homolog 4 pseudogene106766269967670029Rat
1562573Zfp830zinc finger protein 830106770134067702804Rat
7607868LOC102547954uncharacterized LOC102547954106771659967717654Rat
1309875Lig3DNA ligase 3106771780867741141Rat
727916Rfflring finger and FYVE-like domain containing E3 ubiquitin protein ligase106774071167803669Rat
1306944Rad51dRAD51 paralog D106780572067824452Rat
1310708Fndc8fibronectin type III domain containing 8106782595267834090Rat
41195735LOC120095352U6 spliceosomal RNA106782724167827353Rat
1308301Nle1notchless homolog 1106783405967844771Rat
1305666Unc45bunc-45 myosin chaperone B106784546467873143Rat
1312025Slfn5schlafen family member 5106788106867895013Rat

1 to 20 of 154 rows
1 to 20 of 369 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
38936D10Rat98227106694158666941813Ratregion
41468D10Rat155173106697895566979128Ratregion
1579193D10Chm165194106700019867000394Ratregion
5036486Scya274106700593967006013Ratregion
5031338PMC145384P1658106700627067006928Ratregion
5071072RH134870195106700691367007108Ratregion
5048888RH133164218106701797567018193Ratregion
2308866D10Kini1178106702283267023010Ratregion
5088092Scya11102106703176367031865Ratregion
1578900D10Chm166237106705855267058789Ratregion
5028003M23501186106712838467128570Ratregion
1578907D10Chm129225106719003067190253Ratregion
5035044D11Pas4281106720959967209680Ratregion
1579015D10Chm128172106723239867232568Ratregion
5085074D11Pas39563106727398667274549Ratregion
5085076D11Pas45157106728274467282901Ratregion
1579051D10Chm130245106729321667293461Ratregion
1578847D10Chm131164106730023567300399Ratregion
505219122.MMHAP6FLH1.seq153106732978767329940Ratregion
1578918D10Chm167245106733546567335710Ratregion
1 to 20 of 369 rows

Flank 1: (D10Rat27)
Rat AssemblyChrPosition (strand)Source
GRCr81073,950,209 - 73,950,353 (+)Marker Load Pipeline
mRatBN7.21073,452,992 - 73,453,136 (+)MAPPER
Rnor_6.01075,983,662 - 75,983,805NCBI
Rnor_5.01074,127,825 - 74,127,968UniSTS
RGSC_v3.41077,091,834 - 77,092,169RGD
RGSC_v3.41077,091,892 - 77,092,035UniSTS
RGSC_v3.11077,106,262 - 77,106,405RGD
Celera1072,360,629 - 72,360,772UniSTS
RH 3.4 Map10681.99RGD
RH 3.4 Map10681.99UniSTS
RH 2.0 Map10766.2RGD
SHRSP x BN Map1050.9999RGD
FHH x ACI Map1059.2399RGD
Cytogenetic Map10q26UniSTS
Flank 2: (D10Rat98)
Rat AssemblyChrPosition (strand)Source
GRCr81067,439,246 - 67,439,473 (+)Marker Load Pipeline
mRatBN7.21066,941,586 - 66,941,813 (+)MAPPER
Rnor_6.01069,348,233 - 69,348,459NCBI
Rnor_5.01068,983,628 - 68,983,854UniSTS
RGSC_v3.41070,191,139 - 70,191,595RGD
RGSC_v3.41070,191,315 - 70,191,541UniSTS
RGSC_v3.11070,204,762 - 70,205,218RGD
Celera1065,889,346 - 65,889,572UniSTS
RH 2.0 Map10664.3RGD
SHRSP x BN Map1047.6099RGD
FHH x ACI Map1054.8199RGD
Cytogenetic Map10q26UniSTS


1 to 10 of 114 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631565Hcuc4Hepatic copper content QTL 44.15liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106694181373452992Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
12902615Bw185Body weight QTL 1850.01body mass (VT:0001259)body weight (CMO:0000012)107111521772606468Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat

1 to 10 of 114 rows


Database
Acc Id
Source(s)
NCBI Gene Hcuc4

Note Type Note Reference