Mpo (myeloperoxidase) - Rat Genome Database
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Gene: Mpo (myeloperoxidase) Rattus norvegicus
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Symbol: Mpo
Name: myeloperoxidase
RGD ID: 1592081
Description: Exhibits peroxidase activity. Involved in several processes, including response to food; response to gold nanoparticle; and response to lipopolysaccharide. Localizes to extracellular space. Used to study acute kidney failure. Biomarker of chronic obstructive pulmonary disease; cystitis; and renovascular hypertension. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 1; cystic fibrosis; kidney failure (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MPO (myeloperoxidase); PARTICIPATES IN etoposide pharmacodynamics pathway; etoposide pharmacokinetics pathway; interleukin-23 signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (R)-carnitine; (S)-colchicine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Mpo_mapped; myeloperoxidase (mapped)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21072,594,458 - 72,608,862 (+)NCBI
Rnor_6.0 Ensembl1075,087,892 - 75,098,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01075,087,892 - 75,098,260 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01075,004,128 - 75,014,496 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,085,872 - 76,097,012 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1071,507,771 - 71,517,382 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (IDA,ISO)
Acute Lung Injury  (ISO)
alcoholic liver cirrhosis  (ISO)
Alzheimer's disease  (ISO)
Alzheimer's disease 1  (ISO)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISO)
asthma  (ISO)
bacterial pneumonia  (ISO)
brain disease  (ISO)
Brain Injuries  (ISO)
Brain Injuries, Traumatic  (ISO)
brain ischemia  (ISO)
Burns  (IEP,ISO)
cardiovascular system disease  (ISO)
Chronic Bronchitis  (IEP)
chronic obstructive pulmonary disease  (IEP,ISO)
colitis  (ISO)
Contrast-Induced Nephropathy  (IDA)
cystic fibrosis  (ISO)
cystitis  (IEP)
Drug Eruptions  (ISO)
end stage renal disease  (ISO)
Enteritis  (IEP)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (IEP,ISO)
extrahepatic cholestasis  (ISO)
glomerulonephritis  (ISO)
Hemorrhagic Shock  (ISO)
hepatocellular carcinoma  (ISO)
Hypoxia  (ISO)
Inflammation  (ISO)
interstitial lung disease  (ISO)
keratosis  (ISO)
Kidney Calculi  (ISO)
kidney disease  (ISO)
Kidney Reperfusion Injury  (IEP,ISO)
liver cirrhosis  (ISO)
lung cancer  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lupus nephritis  (ISO)
major depressive disorder  (ISO)
Myeloperoxidase Deficiency  (ISO)
Myocardial Ischemia  (ISO)
Occupational Diseases  (ISO)
pancreatic cancer  (ISO)
pancreatitis  (ISO)
pleurisy  (ISO)
pre-malignant neoplasm  (ISO)
Prostatic Neoplasms  (ISO)
renovascular hypertension  (IEP)
Reperfusion Injury  (IEP,ISO)
rheumatoid arthritis  (ISO)
Sepsis  (ISO)
Spinal Cord Injuries  (IEP)
status asthmaticus  (ISO)
Systemic Candidiasis  (ISO)
trichuriasis  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
urticaria  (ISO)
vasculitis  (ISO)
Viral Bronchiolitis  (ISO)
Wounds and Injuries  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (EXP)
(+)-catechin  (ISO)
(+)-epicatechin-3-O-gallate  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid  (ISO)
(R)-camphor  (ISO)
(R)-carnitine  (EXP)
(S)-colchicine  (EXP)
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (ISO)
1,2-phenylenediamine  (ISO)
1,4-benzoquinone  (ISO)
1,7-dimethylxanthine  (ISO)
1-chloro-2,4,6-trinitrobenzene  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
16,16-dimethylprostaglandin E2  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2,4-dichloroaniline  (ISO)
2,4-dimethylaniline  (ISO)
2,6-dihydroxybenzoic acid  (ISO)
2,6-dimethylaniline  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (EXP)
2-amino-2-deoxy-D-galactopyranose  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-arachidonoylglycerol  (ISO)
2-bromohexadecanoic acid  (ISO)
2-naphthylamine  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3,4-dichloroaniline  (ISO)
3,4-dihydroxybenzoic acid  (EXP,ISO)
3,4-dimethylaniline  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-Amino-1-methyl-5H-pyrido[4,3-b]indole  (ISO)
3-aminobenzamide  (ISO)
3-phenylprop-2-enal  (ISO)
4'-hydroxydiclofenac  (ISO)
4,4'-methylene-bis-(2-chloroaniline)  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP,ISO)
4-chloroaniline  (ISO)
4-fluoroaniline  (ISO)
4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester  (ISO)
4-nitroaniline  (ISO)
5,5-dimethyl-1-pyrroline N-oxide  (ISO)
5-(1,4-diazepane-1-sulfonyl)isoquinoline  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-hydroxydiclofenac  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
6-(2,5-dichlorophenyl)-1,3,5-triazine-2,4-diamine  (EXP)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (EXP,ISO)
7,12-dimethyltetraphene  (ISO)
abacavir  (ISO)
acetaldehyde  (ISO)
acetic acid  (EXP,ISO)
acetohydrazide  (ISO)
acetylsalicylic acid  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
albuterol  (ISO)
aldehydo-D-glucosamine  (EXP)
aldehydo-D-glucose  (EXP)
Alkannin  (ISO)
all-trans-retinoic acid  (ISO)
allopurinol  (EXP)
alloxan  (EXP)
alpha-amanitin  (ISO)
aluminium atom  (ISO)
aluminium oxide  (ISO)
aluminium(0)  (ISO)
ambroxol  (EXP)
amifostine  (ISO)
aminoglutethimide  (ISO)
aminoguanidine  (EXP)
amiodarone  (EXP)
ammonia  (ISO)
ammonium chloride  (EXP)
amodiaquine  (ISO)
amphetamine  (EXP)
ampicillin  (EXP)
andrographolide  (EXP)
aniline  (ISO)
anthocyanin  (EXP)
apocynin  (EXP,ISO)
arachidonic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
artesunate  (EXP)
asbestos  (ISO)
astragaloside IV  (EXP)
atorvastatin calcium  (EXP)
baicalein  (ISO)
balsalazide  (ISO)
benzene  (ISO)
benzidine  (ISO)
benzo[a]pyrene  (ISO)
benzohydrazide  (ISO)
benzoic acid  (ISO)
Benzoyl peroxide  (ISO)
beraprost  (ISO)
berberine  (ISO)
Bergenin  (EXP)
beta-carotene  (EXP)
beta-D-glucosamine  (EXP)
biphenyl-4-amine  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP)
Bisphenol A diglycidyl ether  (EXP,ISO)
bivalirudin  (ISO)
bleomycin A2  (EXP,ISO)
Boldine  (ISO)
budesonide  (EXP)
buta-1,3-diene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
Calcimycin  (EXP,ISO)
camphor  (ISO)
candesartan  (EXP)
capsaicin  (EXP)
capsazepine  (EXP,ISO)
CARBENOXOLONE  (ISO)
carbon nanotube  (ISO)
carboplatin  (EXP)
carnosine  (ISO)
carrageenan  (EXP)
carvacrol  (ISO)
carvedilol  (EXP,ISO)
celastrol  (EXP,ISO)
celecoxib  (EXP)
ceric oxide  (EXP,ISO)
cerium trichloride  (ISO)
ceruletide  (ISO)
chalcones  (EXP)
chelerythrine  (ISO)
Chloralose  (ISO)
chlorogenic acid  (ISO)
chlorphenamine  (EXP)
chlorpyrifos  (EXP)
chondroitin sulfate  (EXP)
chrysin  (EXP)
ciprofloxacin  (EXP)
cis-caffeic acid  (ISO)
cisplatin  (EXP,ISO)
clopidogrel  (ISO)
clozapine  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
coumarins  (ISO)
crocidolite asbestos  (EXP,ISO)
crocin-1  (EXP)
cumene hydroperoxide  (ISO)
curcumin  (EXP,ISO)
cyanides  (ISO)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
cypermethrin  (ISO)
cysteamine  (EXP)
D-glucose  (EXP)
D-penicillamine  (ISO)
deoxynivalenol  (ISO)
desmethylnaproxen  (ISO)
dexamethasone  (EXP,ISO)
dextran  (ISO)
dextran sulfate  (EXP,ISO)
diarsenic trioxide  (EXP,ISO)
dibenziodolium  (ISO)
Dibromoacetonitrile  (ISO)
dichlorine  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (EXP,ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (EXP)
diquat  (EXP)
disodium selenite  (EXP)
docebenone  (ISO)
domperidone  (ISO)
donepezil hydrochloride  (ISO)
doxorubicin  (EXP)
edaravone  (EXP)
emodin  (EXP)
enalapril  (EXP)
erdosteine  (EXP)
ethanol  (EXP,ISO)
etoposide  (ISO)
eugenol  (EXP)
famotidine  (EXP,ISO)
fasudil hydrochloride  (ISO)
fenoterol  (ISO)
ferroheme b  (EXP)
fisetin  (EXP)
flucloxacillin  (ISO)
fluconazole  (EXP)
folic acid  (ISO)
formaldehyde  (EXP)
fucoidan  (EXP,ISO)
fulvestrant  (EXP)
gadolinium trichloride  (EXP)
gallic acid  (EXP,ISO)
gallocatechin  (ISO)
gamma-hexachlorocyclohexane  (EXP)
gemcitabine  (ISO)
genistein  (EXP)
gentamycin  (EXP)
geraniol  (EXP,ISO)
gingerol  (EXP,ISO)
ginsenoside Re  (ISO)
gliclazide  (EXP)
glucose  (EXP)
glutathione  (ISO)
glutathione disulfide  (ISO)
glyburide  (EXP)
GR 113808  (ISO)
granisetron  (ISO)
halothane  (EXP)
heme b  (EXP)
hemin  (EXP)
hesperetin  (ISO)
hesperidin  (EXP)
hyaluronic acid  (EXP)
hydrazine  (ISO)
hydrogen chloride  (EXP,ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxamic acid  (EXP)
hypochlorous acid  (ISO)
ibuprofen  (EXP)
imiquimod  (ISO)
IMP  (EXP)
indole-3-butyric acid  (EXP)
indometacin  (EXP,ISO)
irinotecan  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
isatin  (EXP)
isoflurane  (EXP)
isoniazide  (ISO)
isoorientin  (EXP)
isoprenaline  (EXP)
ketoprofen  (EXP)
ketorolac  (EXP)
L-arginine  (EXP)
L-ascorbic acid  (EXP,ISO)
L-cysteine  (ISO)
L-leucine  (ISO)
L-threonine  (ISO)
Lafutidine  (EXP)
lansoprazole  (EXP)
lipopolysaccharide  (EXP,ISO)
lipoxin A4  (ISO)
liquiritigenin  (EXP)
liquiritin  (EXP)
lisinopril dihydrate  (ISO)
loxoprofen  (EXP)
lupeol  (ISO)
malathion  (EXP)
manganese atom  (EXP)
manganese(0)  (EXP)
manganese(II) chloride  (EXP,ISO)
mangiferin  (ISO)
mechlorethamine  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
mesalamine  (EXP,ISO)
Mesna  (ISO)
metacetamol  (ISO)
metformin  (ISO)
methimazole  (EXP)
methotrexate  (EXP)
methylene blue  (EXP)
metoclopramide  (ISO)
mirtazapine  (EXP)
MK 571  (ISO)
ML-7  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monocrotaline  (EXP,ISO)
monotropein  (ISO)
montelukast  (EXP)
N'-acetylisoniazid  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N,N-dimethylformamide  (ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
N-[3-(aminomethyl)benzyl]acetamidine  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-ethyl-N-nitrosourea  (ISO)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
n-propyl gallate  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
naproxen  (ISO)
naringin  (EXP)
nickel atom  (EXP)
nickel dichloride  (EXP)
nickel sulfate  (ISO)
nicorandil  (EXP)
nicotine  (EXP)
nimesulide  (EXP,ISO)
nitric oxide  (EXP)
nitroflurbiprofen  (EXP)
nitrogen dioxide  (ISO)
nitroglycerin  (EXP)
nitrososulfamethoxazole  (ISO)
notoginsenoside R1  (EXP,ISO)
NSC 23766  (ISO)
o-anisidine  (ISO)
o-toluidine  (ISO)
octadecanoic acid  (ISO)
olaparib  (ISO)
olmesartan  (EXP)
Olmesartan medoxomil  (EXP)
omeprazole  (EXP,ISO)
oxaliplatin  (ISO)
p-toluidine  (ISO)
pantoprazole  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentobarbital  (EXP)
Pentoxifylline  (EXP)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenethyl caffeate  (EXP)
phenol  (ISO)
phenol red  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (EXP)
platycodin D  (EXP)
polymyxin B2  (ISO)
Potassium 2,6-dihydroxytriazinecarboxylate  (EXP)
potassium chloride  (ISO)
potassium cyanide  (ISO)
prednisolone  (EXP,ISO)
probenecid  (ISO)
procainamide  (ISO)
procyanidin B2  (EXP)
progesterone  (ISO)
prostaglandin E2  (EXP)
pyridaben  (ISO)
Pyridostigmine bromide  (EXP)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (EXP,ISO)
raloxifene  (EXP)
ranitidine  (EXP)
Rebamipide  (EXP,ISO)
resolvin D1  (ISO)
resolvin D2  (ISO)
resorcinol  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (EXP)
rifaximin  (ISO)
rolipram  (EXP,ISO)
rosmarinic acid  (EXP)
rotenone  (EXP,ISO)
ruthenium red  (ISO)
S-allylcysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
salicylic acid  (ISO)
saxagliptin  (EXP)
SB 203580  (EXP,ISO)
Scalaradial  (ISO)
serotonin  (ISO)
serpentine asbestos  (ISO)
sevoflurane  (EXP)
sildenafil citrate  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP,ISO)
Sinomenine  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium azide  (ISO)
sodium cyanide  (ISO)
sodium fluoride  (EXP)
sodium hypochlorite  (ISO)
sodium nitrate  (EXP)
spironolactone  (EXP)
stattic  (ISO)
streptozocin  (EXP,ISO)
sulfamethoxazole  (ISO)
sulfasalazine  (EXP,ISO)
sulfur dioxide  (EXP)
superoxide  (ISO)
synephrine  (ISO)
syringic acid  (ISO)
T-2 toxin  (ISO)
tacrolimus hydrate  (EXP)
taurine  (EXP,ISO)
taurocholic acid  (EXP)
telmisartan  (EXP,ISO)
terbufos  (ISO)
terbutaline  (ISO)
tetrachloromethane  (EXP,ISO)
tetramethylpyrazine  (ISO)
thalidomide  (ISO)
theophylline  (EXP,ISO)
thiabendazole  (ISO)
thiazolidines  (EXP)
thioacetamide  (EXP,ISO)
thiophenes  (ISO)
thymoquinone  (EXP)
tiquizium bromide  (EXP)
titanium dioxide  (ISO)
trans-caffeic acid  (ISO)
tributylstannane  (EXP)
trichloroacetic acid  (ISO)
trichostatin A  (ISO)
Triptolide  (ISO)
troglitazone  (ISO)
tropisetron  (EXP,ISO)
tungsten  (ISO)
umbelliferone  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
usnic acid  (EXP)
valproic acid  (ISO)
verapamil  (EXP)
vinclozolin  (EXP)
Vinpocetine  (ISO)
vitamin E  (EXP)
warfarin  (EXP)
WIN 55212-2  (ISO)
wortmannin  (EXP,ISO)
zafirlukast  (EXP)
zearalenone  (ISO)
zileuton  (EXP,ISO)
zinc atom  (EXP)
zinc oxide  (ISO)
zinc protoporphyrin  (EXP)
zinc sulfate  (EXP)
zinc(0)  (EXP)

References

References - curated
1. Abul H, etal., Mol Cell Biochem. 2001 Jan;217(1-2):107-12.
2. Ahsan H, etal., Cancer Lett. 2003 Nov 10;201(1):57-65.
3. Andersen GN, etal., Respir Med. 2007 Oct;101(10):2199-206. Epub 2007 Jul 20.
4. Aratani Y, etal., J Infect Dis. 2002 Jun 15;185(12):1833-7. doi: 10.1086/340635. Epub 2002 May 16.
5. Barlak A, etal., Ren Fail. 2010;32(8):992-9.
6. Bouali H, etal., J Rheumatol. 2007 Oct;34(10):2028-34. Epub 2007 Sep 15.
7. Brovkovych V, etal., Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L96-103. Epub 2008 Apr 18.
8. Cevik O, etal., Burns. 2012 Sep;38(6):861-71. doi: 10.1016/j.burns.2012.01.006. Epub 2012 Feb 20.
9. Clifton MS, etal., Am J Physiol Gastrointest Liver Physiol. 2007 Mar 15;.
10. Edwards ML, etal., J Med Chem. 1994 Dec 9;37(25):4357-62.
11. El Kebir D, etal., Am J Respir Crit Care Med. 2009 Aug 15;180(4):311-9. Epub 2009 May 29.
12. Ersahin M, etal., J Pineal Res. 2009 Aug;47(1):97-106. Epub 2009 Jun 22.
13. Ersahin M, etal., Prostaglandins Other Lipid Mediat. 2012 Sep 15. pii: S1098-8823(12)00119-0. doi: 10.1016/j.prostaglandins.2012.09.002.
14. Fiorini G, etal., Biomed Pharmacother. 2000 Jun;54(5):274-8.
15. Frode TS and Medeiros YS, Mediators Inflamm. 2001 Aug;10(4):223-7.
16. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
17. Gu J, etal., Acta Anaesthesiol Scand. 2011 Nov;55(10):1272-8. doi: 10.1111/j.1399-6576.2011.02526.x. Epub 2011 Sep 26.
18. Guilpain P, etal., Eur Respir J. 2010 Nov 11.
19. Kalayci O, etal., Turk J Pediatr. 2000 Jan-Mar;42(1):9-16.
20. Kantarci OH, etal., J Neuroimmunol 2000 Jun 26;105(2):189-94.
21. Karakoyun B, etal., Drug Chem Toxicol. 2009;32(4):312-8.
22. Kawashima S, etal., Nihon Jinzo Gakkai Shi. 2009;51(1):56-67.
23. Linares-Fernandez B and Alfieri AB, Invest Clin. 2009 Mar;50(1):23-33.
24. Ma N, etal., Zhonghua Nei Ke Za Zhi. 1999 Aug;38(8):523-6.
25. Matthijsen RA, etal., Am J Pathol. 2007 Dec;171(6):1743-52. Epub 2007 Nov 30.
26. Menozzi A, etal., Eur J Pharmacol. 2011 Jan 10;650(1):378-83. Epub 2010 Oct 13.
27. Miles RR, etal., J Cell Biochem. 1998 Mar 1;68(3):355-65.
28. Misaka S, etal., Eur J Pharm Sci. 2009 Jun 28;37(3-4):469-76. Epub 2009 Apr 10.
29. Nahon P, etal., Hepatology. 2009 Nov;50(5):1484-93. doi: 10.1002/hep.23187.
30. Nahon P, etal., J Hepatol. 2012 Feb;56(2):426-32. doi: 10.1016/j.jhep.2011.08.010. Epub 2011 Sep 8.
31. Narasaraju TA, etal., Am J Physiol Lung Cell Mol Physiol 2003 Nov;285(5):L1037-45. Epub 2003 Aug 15.
32. Odobasic D, etal., J Am Soc Nephrol. 2007 Mar;18(3):760-70. Epub 2007 Jan 31.
33. OMIM Disease Annotation Pipeline
34. Pecoits-Filho R, etal., Kidney Int Suppl. 2003 May;(84):S172-6.
35. Pereira DV, etal., Invest Ophthalmol Vis Sci. 2012 Dec 7;53(13):8036-41. doi: 10.1167/iovs.12-10743.
36. Perianayagam MC, etal., Kidney Int. 2012 Oct;82(8):909-19. doi: 10.1038/ki.2012.235. Epub 2012 Jun 27.
37. Pipeline to import KEGG annotations from KEGG into RGD
38. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
39. Pipeline to import SMPDB annotations from SMPDB into RGD
40. Polonikov AV, etal., J Asthma. 2009 Jun;46(5):523-8.
41. Reynolds WF, etal., Mediators Inflamm. 2006;2006(2):36735.
42. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
43. RGD automated import pipeline for gene-chemical interactions
44. Sawicki M, etal., Eur J Clin Invest. 2011 Jan 12. doi: 10.1111/j.1365-2362.2010.02457.x.
45. Schabath MB, etal., Am J Epidemiol. 2005 Mar 1;161(5):412-22.
46. Sigurs N, etal., Acta Paediatr. 1994 Nov;83(11):1151-5.
47. Sommer SP, etal., J Heart Lung Transplant. 2011 Apr 4.
48. Son TG, etal., Free Radic Res. 2005 Mar;39(3):283-9.
49. Tasdemir C, etal., Ren Fail. 2012;34(9):1144-9. doi: 10.3109/0886022X.2012.717490. Epub 2012 Sep 6.
50. Tsao KC, etal., J Clin Lab Anal. 2007;21(6):426-31.
51. Uluoglu C, etal., Gen Physiol Biophys. 2008 Mar;27(1):25-31.
52. Vasu VT, etal., Free Radic Res. 2011 Feb;45(2):165-76. Epub 2010 Oct 18.
53. Wang AY, etal., Am J Kidney Dis. 2010 Nov;56(5):937-46. Epub 2010 Jul 16.
54. Wheatley-Price P, etal., Cancer. 2008 Mar 1;112(5):1037-42.
55. Yamanishi Y, etal., Mod Rheumatol. 2012 Oct 21.
Additional References at PubMed
PMID:2981589   PMID:10085024   PMID:10772654   PMID:11792727   PMID:11907569   PMID:11980719   PMID:12089442   PMID:14613914   PMID:14651853   PMID:15159534   PMID:15878909   PMID:16502470  
PMID:17072967   PMID:17950080   PMID:18283562   PMID:18617697   PMID:19056867   PMID:19301098   PMID:19330621   PMID:20228064   PMID:21327394   PMID:21630459   PMID:21704008   PMID:23376485  
PMID:23533145   PMID:23691142   PMID:24035742   PMID:25404055   PMID:25645918   PMID:26474698   PMID:28131839   PMID:28466093   PMID:29270751   PMID:31132398   PMID:32762560  


Genomics

Candidate Gene Status
Mpo is a candidate Gene for QTL Bp308
Comparative Map Data
Mpo
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21072,594,458 - 72,608,862 (+)NCBI
Rnor_6.0 Ensembl1075,087,892 - 75,098,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01075,087,892 - 75,098,260 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01075,004,128 - 75,014,496 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,085,872 - 76,097,012 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1071,507,771 - 71,517,382 (+)NCBICelera
Cytogenetic Map10q26NCBI
MPO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1758,269,855 - 58,280,935 (-)EnsemblGRCh38hg38GRCh38
GRCh381758,269,855 - 58,280,935 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371756,347,216 - 56,358,296 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361753,702,216 - 53,713,295 (-)NCBINCBI36hg18NCBI36
Build 341753,702,215 - 53,713,295NCBI
Celera1752,808,995 - 52,820,066 (-)NCBI
Cytogenetic Map17q22NCBI
HuRef1751,708,013 - 51,718,966 (-)NCBIHuRef
CHM1_11756,412,238 - 56,423,315 (-)NCBICHM1_1
Mpo
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391187,684,610 - 87,695,238 (+)NCBIGRCm39mm39
GRCm39 Ensembl1187,684,407 - 87,695,239 (+)Ensembl
GRCm381187,793,784 - 87,804,412 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1187,793,581 - 87,804,413 (+)EnsemblGRCm38mm10GRCm38
MGSCv371187,607,286 - 87,617,914 (+)NCBIGRCm37mm9NCBIm37
MGSCv361187,609,776 - 87,620,592 (+)NCBImm8
Celera1197,389,547 - 97,400,150 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1152.22NCBI
Mpo
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554514,743,744 - 4,753,358 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554514,743,744 - 4,753,358 (+)NCBIChiLan1.0ChiLan1.0
MPO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11757,189,654 - 57,212,111 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1757,201,073 - 57,212,111 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01752,333,882 - 52,357,838 (-)NCBIMhudiblu_PPA_v0panPan3
MPO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl932,927,483 - 32,937,820 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1932,927,483 - 32,938,007 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Mpo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364904,809,773 - 4,819,070 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1234,556,408 - 34,567,904 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11234,557,031 - 34,570,091 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21236,245,391 - 36,256,372 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MPO
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11635,120,194 - 35,130,851 (+)NCBI
ChlSab1.1 Ensembl1635,120,581 - 35,130,671 (+)Ensembl
Mpo
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624871121,026 - 131,433 (-)NCBI

Position Markers
D10Chm35  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01075,090,892 - 75,091,129NCBIRnor6.0
Rnor_5.01075,011,259 - 75,011,496UniSTSRnor5.0
RGSC_v3.41076,088,872 - 76,089,109UniSTSRGSC3.4
Celera1071,510,771 - 71,511,006UniSTS
Cytogenetic Map10q26UniSTS
RH144619  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01075,097,721 - 75,098,258NCBIRnor6.0
Rnor_5.01075,004,130 - 75,004,667UniSTSRnor5.0
RGSC_v3.41076,096,473 - 76,097,010UniSTSRGSC3.4
Celera1071,516,843 - 71,517,380UniSTS
Cytogenetic Map10q26UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10622909575983805Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10642907599492409Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109841807108540162Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101482789492423564Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014827894107857673Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014827894110992275Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)1020170031102897474Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102152390683549467Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12152390690312401Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)12152390690312401Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102152390690312401Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102290149793886300Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1023861015112626471Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1024483076107857673Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)1027237530101482600Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1027237530102427718Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103009990975099909Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103009990975099909Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)103098380575983805Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103191939778343192Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103317903078179030Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103334319278343192Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103513942480139424Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103618592982675365Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103618592995845311Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)104051404485514044Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)104051404485514044Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1041260363106105607Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1041260363107857673Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1041260363107857673Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104318865981042642Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1043289657108540162Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104370495588704955Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104659302198939209Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104684834691848346Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104684834691848346Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104684834691848346Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)105063833795638337Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)105128920384596393Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)105128920384596393Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)105128920384596393Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)105128920384596393Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)105128920384596393Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105310471898104718Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1053621375112626471Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1053621375112626471Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105362581598939209Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105363748594807701Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)1055224855100224855Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1055678976112626471Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)1055679084102427604Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1056698730101698730Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1060450007105450007Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1060875260105875260Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1060875260105875260Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1060875260105875260Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1062096293107096293Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106464817584601269Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)1064648175101691360Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1064648175102149713Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1064648175102149713Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106464831185513822Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1065590122110590122Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1065992275110992275Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1065992275110992275Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1067880046112626471Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1067988218110992091Rat
2298481Eau9Experimental allergic uveoretinitis QTL 90.0169uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)106830503785514044Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1069123603101482600Rat
631565Hcuc4Hepatic copper content QTL 44.15hepatic copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106934845975983662Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1069385595112626471Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1069385595112626471Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106991083276109716Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1070166960112626471Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1070800069112626471Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1071692298112626471Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1073008136112626471Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1073008136112626471Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1073008136112626471Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1073467158112626471Rat
1579918Bp279Blood pressure QTL 2790.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107372791775099909Rat
12903245Cm110Cardiac mass QTL 1100.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)107372791775099909Rat
12903246Cm111Cardiac mass QTL 1110.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)107372791775099909Rat
12903247Cm112Cardiac mass QTL 1120.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)107372791775099909Rat
12903248Am14Aortic mass QTL 140.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)107372791775099909Rat
12903249Kidm68Kidney mass QTL 680.02kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)107372791775099909Rat
12902615Bw185Body weight QTL 1850.01body mass (VT:0001259)body weight (CMO:0000012)107372791775099909Rat
2306793Ean5Experimental allergic neuritis QTL 54.7nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)107504539197308358Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:228
Count of miRNA genes:171
Interacting mature miRNAs:187
Transcripts:ENSRNOT00000065910, ENSRNOT00000066474
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 37 24 11 24 2
Low 2 5 5 2 8 2 2 2 3 26 25 8 2
Below cutoff 1 29 10 10 10 6 9 26 8 11 1 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000065910   ⟹   ENSRNOP00000062232
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1075,087,892 - 75,098,260 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000066474   ⟹   ENSRNOP00000059901
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1075,089,928 - 75,097,933 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000081951   ⟹   ENSRNOP00000071759
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1075,088,422 - 75,098,258 (+)Ensembl
RefSeq Acc Id: NM_001107036   ⟹   NP_001100506
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21072,594,458 - 72,604,819 (+)NCBI
Rnor_6.01075,087,892 - 75,098,260 (+)NCBI
Rnor_5.01075,004,128 - 75,014,496 (-)NCBI
RGSC_v3.41076,085,872 - 76,097,012 (+)RGD
Celera1071,507,771 - 71,517,382 (+)RGD
Sequence:
RefSeq Acc Id: XM_006247095   ⟹   XP_006247157
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21072,594,883 - 72,604,819 (+)NCBI
Rnor_6.01075,088,113 - 75,098,260 (+)NCBI
Rnor_5.01075,004,128 - 75,014,496 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247096   ⟹   XP_006247158
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21072,594,883 - 72,604,694 (+)NCBI
Rnor_6.01075,088,112 - 75,098,161 (+)NCBI
Rnor_5.01075,004,128 - 75,014,496 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039086051   ⟹   XP_038941979
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21072,594,883 - 72,608,862 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001100506 (Get FASTA)   NCBI Sequence Viewer  
  XP_006247157 (Get FASTA)   NCBI Sequence Viewer  
  XP_006247158 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941979 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM05612 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001100506   ⟸   NM_001107036
- Peptide Label: precursor
- UniProtKB: D3ZGE2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247157   ⟸   XM_006247095
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K1A2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247158   ⟸   XM_006247096
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K1A2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000062232   ⟸   ENSRNOT00000065910
RefSeq Acc Id: ENSRNOP00000059901   ⟸   ENSRNOT00000066474
RefSeq Acc Id: ENSRNOP00000071759   ⟸   ENSRNOT00000081951
RefSeq Acc Id: XP_038941979   ⟸   XM_039086051
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1592081 AgrOrtholog
Ensembl Genes ENSRNOG00000008310 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000059901 UniProtKB/TrEMBL
  ENSRNOP00000062232 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000071759 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000065910 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000066474 UniProtKB/TrEMBL
  ENSRNOT00000081951 UniProtKB/TrEMBL
Gene3D-CATH 1.10.640.10 UniProtKB/TrEMBL
InterPro Haem_peroxidase UniProtKB/TrEMBL
  Haem_peroxidase_animal_sg UniProtKB/TrEMBL
  Haem_peroxidase_sf UniProtKB/TrEMBL
  MPO UniProtKB/TrEMBL
KEGG Report rno:303413 UniProtKB/TrEMBL
NCBI Gene 303413 ENTREZGENE
PANTHER PTHR11475:SF108 UniProtKB/TrEMBL
Pfam An_peroxidase UniProtKB/TrEMBL
PharmGKB MPO RGD
PhenoGen Mpo PhenoGen
PRINTS ANPEROXIDASE UniProtKB/TrEMBL
PROSITE PEROXIDASE_3 UniProtKB/TrEMBL
Superfamily-SCOP Peroxidase_super UniProtKB/TrEMBL
UniProt A0A0G2K1A2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZGE2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZYH8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2007-04-13   myeloperoxidase  Mpo  myeloperoxidase (mapped)  Name updated 737654 APPROVED
2007-04-11 Mpo  myeloperoxidase (mapped)  Mpo_mapped  myeloperoxidase (mapped)  Data Merged 737654 APPROVED
2006-11-20 Mpo  myeloperoxidase (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Mpo_mapped  myeloperoxidase (mapped)      Symbol and Name updated 1556543 APPROVED
2002-06-10 Mpo  Myeloperoxidase      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease may contribute to hyperoxia-mediated lung injury via nitration of proteins, resulting in reactive nitrogen species 1302251
gene_expression expressed in lung tissue 1302251
gene_function mediates protein nitration during hypoxia 1302251