Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Mpo (myeloperoxidase) Rattus norvegicus
Analyze
Symbol: Mpo
Name: myeloperoxidase
RGD ID: 1592081
Description: Exhibits peroxidase activity. Involved in several processes, including response to food; response to gold nanoparticle; and response to lipopolysaccharide. Localizes to extracellular space. Used to study acute kidney failure. Biomarker of chronic obstructive pulmonary disease; cystitis; and renovascular hypertension. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 1; cystic fibrosis; kidney failure (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MPO (myeloperoxidase); PARTICIPATES IN etoposide pharmacodynamics pathway; etoposide pharmacokinetics pathway; interleukin-23 signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (R)-carnitine; (S)-colchicine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Mpo_mapped; myeloperoxidase (mapped)
Orthologs:
Homo sapiens (human) : MPO (myeloperoxidase)  HGNC  Alliance
Mus musculus (house mouse) : Mpo (myeloperoxidase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mpo (myeloperoxidase)
Pan paniscus (bonobo/pygmy chimpanzee) : MPO (myeloperoxidase)
Canis lupus familiaris (dog) : MPO (myeloperoxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpo (myeloperoxidase)
Sus scrofa (pig) : MPO (myeloperoxidase)
Chlorocebus sabaeus (African green monkey) : MPO (myeloperoxidase)
Heterocephalus glaber (naked mole-rat) : Mpo (myeloperoxidase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01075,087,892 - 75,098,260 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1075,087,892 - 75,098,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01075,004,128 - 75,014,496 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,085,872 - 76,097,012 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1071,507,771 - 71,517,382 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mpo
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1592081
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-08-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.