Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing post-transcriptional repressor activity. Involved in several processes, including cellular response to mechanical stimulus; negative regulation of programmed cell death; and positive regulation of NLRP3 inflammasome complex assembly. Located in extracellular vesicle. Used to study glioblastoma; status epilepticus; and thyroid gland cancer. Biomarker of several diseases, including cerebral infarction; diabetic retinopathy; liver cirrhosis; pulmonary hypertension; and status epilepticus. Orthologous to human MIR21 (microRNA 21); INTERACTS WITH (R)-lipoic acid; 17beta-estradiol; 2,5-hexanedione.
Cyclosporine inhibits the reaction [Thioctic Acid promotes the reaction [Acetic Acid results in increased expression of MIR21 mRNA]], Thioctic Acid promotes the reaction [Acetic Acid results in increased expression of MIR21 mRNA]
[Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3, 3-bis(2-aminoethyl)-1-triazene] results in increased expression of MIR21 mRNA
[Dronabinol inhibits the reaction [Antigens results in increased expression of MIR21A mRNA]] which results in decreased expression of IFNG mRNA, Dronabinol inhibits the reaction [Antigens results in increased expression of MIR21A mRNA]
MIR21 mRNA promotes the reaction [Arsenic Trioxide results in decreased expression of KCNH2 protein], MIR21 mRNA promotes the reaction [Arsenic Trioxide results in decreased expression of SP1 protein]
baicalein inhibits the reaction [TGFB1 protein results in increased expression of MIR21 mRNA], MIR21 mRNA inhibits the reaction [baicalein inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]
[Air Pollutants results in increased abundance of [Carbon co-treated with Particulate Matter]] which results in increased expression of MIR21 mRNA more ...
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR21 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[MIR21 mRNA results in decreased susceptibility to Cisplatin] which results in increased phosphorylation of AKT1 protein] more ...
Cyclosporine inhibits the reaction [Thioctic Acid promotes the reaction [Acetic Acid results in increased expression of MIR21 mRNA]], Cyclosporine promotes the reaction [Acetic Acid results in increased expression of MIR21 mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dehydroepiandrosterone results in increased expression of MIR21 mRNA] more ...
MIR21 mRNA promotes the reaction [Arsenic Trioxide results in decreased expression of KCNH2 protein], MIR21 mRNA promotes the reaction [Arsenic Trioxide results in decreased expression of SP1 protein]
[Air Pollutants results in increased abundance of [Carbon co-treated with Particulate Matter]] which results in increased expression of MIR21 mRNA more ...
[Resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased expression of MIR21 mRNA, ferulic acid inhibits the reaction [Thioacetamide results in increased expression of MIR21 mRNA]
Cyclosporine inhibits the reaction [Thioctic Acid promotes the reaction [Acetic Acid results in increased expression of MIR21 mRNA]], Thioctic Acid promotes the reaction [Acetic Acid results in increased expression of MIR21 mRNA]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[MIR21 mRNA results in decreased susceptibility to Cisplatin] which results in increased phosphorylation of AKT1 protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [MIR21 mRNA results in decreased susceptibility to Cisplatin]
Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of MIR21 mRNA], Acetylcysteine inhibits the reaction [Vehicle Emissions affects the expression of MIR21 mRNA]
[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MIR21 mRNA
MIR21 mRNA affects the reaction [sporidesmin affects the expression of CYP2C8 mRNA], MIR21 mRNA affects the reaction [sporidesmin results in increased expression of CYP2C18 mRNA]
[Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides co-treated with Carbon Monoxide]] which results in increased expression of MIR21 mRNA, [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of MIR21 mRNA
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MIR21 mRNA