Bw185 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bw185 (Body weight QTL 185) Rattus norvegicus

Symbol: Bw185
Name: Body weight QTL 185
RGD ID: 12902615
Previously known as: BpcakmC10QTL1; C10QTL1
Trait: body mass   (VT:0001259)    
Measurement Type: body weight   (CMO:0000012)    
LOD Score: Not Available
P Value: 0.01
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21071,115,217 - 72,606,468RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01073,727,917 - 75,099,909RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01073,626,664 - 75,002,634RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41074,524,802 - 76,098,661RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SS.LEW-(D10Chm224-D10Chm6)/Ayd 




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw185Rathypertension  IAGP 1599557 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw185Ratabnormal body weight  IAGP 1599557 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw185Ratbody weight  IDA 1599557 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw185Ratcontrolled sodium content diet  IDA 1599557 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw185Ratscale  IDA 1599557 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw185RatSS.LEW-(D10Chm224-D10Chm6)/Ayd  IEA 1599557 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw185Ratbody mass  IDA 1599557 RGD 


#
Reference Title
Reference Citation
1. Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension. Charron S, etal., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14.
2. Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Duong C, etal., Mamm Genome. 2006 Dec;17(12):1147-61. Epub 2006 Dec 1.


1 to 20 of 47 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1304829Med13mediator complex subunit 13107108697871176535Rat
41033403LOC120095332uncharacterized LOC120095332107124763471250157Rat
41293538LOC120095364U6 spliceosomal RNA107126266271262766Rat
1562411Rnft1ring finger protein, transmembrane 1107131005271322507Rat
620683Rps6kb1ribosomal protein S6 kinase B1107132377771367908Rat
1311967Tubd1tubulin, delta 1107136793671391387Rat
70367Vmp1vacuole membrane protein 1107140505871505045Rat
2325598Mir21microRNA 21107140525771405348Rat
1306819Ptrh2peptidyl-tRNA hydrolase 2107150511371515297Rat
2364Cltcclathrin heavy chain107151766171574591Rat
1359618Dhx40DEAH-box helicase 40107158454671621479Rat
41062475LOC120095163uncharacterized LOC120095163107165620171659142Rat
9226275LOC103693408uncharacterized LOC103693408107165917271663392Rat
41089124LOC120095164uncharacterized LOC120095164107169038771708506Rat
1311564Ypel2yippee-like 2107174630871803843Rat
1311813Gdpd1glycerophosphodiester phosphodiesterase domain containing 1107184049771883936Rat
7748685Ifitm1-ps1interferon induced transmembrane protein 1, pseudogene 1107185252571854443Rat
41161246LOC120095167uncharacterized LOC120095167107188412771892284Rat
1306862Smg8SMG8 nonsense mediated mRNA decay factor107188674271895776Rat
1561541Prr11proline rich 11107189885871943325Rat

1 to 20 of 47 rows
1 to 20 of 97 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
39908D10Rat194243107221929472219541Ratregion
38372D10Rat152213107174710171747314Ratregion
39114D10Rat87199107255221772552416Ratregion
44768D10Got95182107112789071128073Ratregion
44770D10Got100187107192754471927731Ratregion
44773D10Wox5153107172764071728178Ratregion
44773D10Wox5153107172802471728178Ratregion
1578825D10Chm6194107250882572509024Ratregion
1578832D10Chm42165107245620872456373Ratregion
1578839D10Chm79222107111521771115441Ratregion
1578841D10Chm73238107240197972402216Ratregion
1578843D10Chm243249107259009072590339Ratregion
1578858D10Chm123205107255225972552464Ratregion
1578859D10Chm194243107257046172570704Ratregion
1578866D10Chm259227107183175671831983Ratregion
1578891D10Chm29156107260631272606468Ratregion
1578901D10Chm214221107139761571397836Ratregion
1578939D10Chm69216107118921771189433Ratregion
1578942D10Chm5239107203097072031209Ratregion
1578951D10Chm70216107143130771431523Ratregion
1 to 20 of 97 rows

Flank 1: (D10Chm79)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21071,115,217 - 71,115,441 (+)MAPPER
Rnor_6.01073,727,917 - 73,728,138NCBI
Rnor_5.01073,626,664 - 73,626,885UniSTS
RGSC_v3.41074,524,802 - 74,525,023UniSTS
Celera1070,037,717 - 70,037,938UniSTS
Cytogenetic Map10q26UniSTS
Flank 2: (D10Chm29)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21072,606,312 - 72,606,468 (+)MAPPER
Rnor_6.01075,099,754 - 75,099,909NCBI
Rnor_5.01075,002,479 - 75,002,634UniSTS
RGSC_v3.41076,098,506 - 76,098,661UniSTS
Celera1071,518,876 - 71,519,031UniSTS
Cytogenetic Map10 RGD


1 to 10 of 94 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631565Hcuc4Hepatic copper content QTL 44.15liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106694181373452992Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105166340575085664Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
12903245Cm110Cardiac mass QTL 1100.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)107111521772606468Rat
12903246Cm111Cardiac mass QTL 1110.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)107111521772606468Rat

1 to 10 of 94 rows


Note Type Note Reference
qtl_general number of animals used: 11 gender: male 1599557
qtl_general also affects cardiac mass, heart right and left ventricle mass, aortic mass, kidney mass and blood pressure 1599557
qtl_statistics_details software package used: ANOVA followed by Dunnett test in the SYSTAT 9 program 1599557
qtl_trait_method measurement method: selected males were weaned at 21 days of age, then fed a 2% NaCl diet starting from 35 days of age; at 14 weeks animals were weighed 1599557