(-)-gambogic acid decreases activity ISO RGD:731644 6480464 gambogic acid results in decreased activity of RPS6KB1 protein CTD PMID:19433130 (S)-nicotine multiple interactions ISO RGD:731644 6480464 [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:30259641 , PMID:31926917 (S)-nicotine multiple interactions ISO RGD:731645 6480464 Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:31926917 (S)-nicotine increases phosphorylation ISO RGD:731644 6480464 Nicotine results in increased phosphorylation of RPS6KB1 protein CTD PMID:30259641 1,1'-azobis(N,N-dimethylformamide) increases phosphorylation ISO RGD:731644 6480464 Diamide results in increased phosphorylation of RPS6KB1 protein CTD PMID:16183647 1,1'-azobis(N,N-dimethylformamide) multiple interactions ISO RGD:731644 6480464 [Diamide results in increased activity of MTOR protein] which results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:16183647 1,2-dichloroethane decreases expression ISO RGD:731645 6480464 ethylene dichloride results in decreased expression of RPS6KB1 mRNA CTD PMID:28960355 1,2-dimethylhydrazine affects expression ISO RGD:731645 6480464 1, 2-Dimethylhydrazine affects the expression of RPS6KB1 mRNA CTD PMID:22206623 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation ISO RGD:731644 6480464 lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein CTD PMID:17919812 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation EXP 6480464 lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein CTD PMID:14769825 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO RGD:731644 6480464 resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein] CTD PMID:17919812 1-octadec-9-enoylglycero-3-phosphate multiple interactions EXP 6480464 1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:14769825 14,15-EET increases phosphorylation ISO RGD:731644 6480464 14 more ... CTD PMID:16286479 14-Deoxy-11,12-didehydroandrographolide multiple interactions ISO RGD:731645 6480464 14-deoxy-11 more ... CTD PMID:30248417 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO RGD:731645 6480464 [15-deoxy-delta(12 more ... CTD PMID:16611854 17beta-estradiol increases phosphorylation ISO RGD:731644 6480464 Estradiol results in increased phosphorylation of RPS6KB1 protein CTD PMID:16033851 , PMID:31614463 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of RPS6KB1 protein CTD PMID:22465879 17beta-estradiol multiple interactions ISO RGD:731644 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:16033851 more ... 17beta-hydroxy-5alpha-androstan-3-one multiple interactions EXP 6480464 Dihydrotestosterone inhibits the reaction [FSHB protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:17510244 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:731645 6480464 2 more ... CTD PMID:29264491 2,2',4,4'-Tetrabromodiphenyl ether increases phosphorylation ISO RGD:731645 6480464 2 more ... CTD PMID:29264491 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:731645 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of RPS6KB1 mRNA CTD PMID:33387578 2-amino-2-deoxy-D-glucopyranose decreases phosphorylation ISO RGD:731644 6480464 Glucosamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19254699 2-deoxy-D-glucose decreases phosphorylation ISO RGD:731644 6480464 Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16183647 2-deoxy-D-glucose multiple interactions ISO RGD:731644 6480464 Deoxyglucose results in increased phosphorylation of and results in increased activity of RPS6KB1 protein, oxophenylarsine inhibits the reaction [Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:16183647 , PMID:23041229 2-hydroxypropanoic acid decreases expression ISO RGD:731644 6480464 Lactic Acid results in decreased expression of RPS6KB1 mRNA CTD PMID:30851411 3,3',5-triiodo-L-thyronine decreases phosphorylation ISO RGD:731645 6480464 Triiodothyronine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30209975 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:731645 6480464 6-chloro-2 more ... CTD PMID:30209975 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [Phenylephrine results in increased activity of RPS6KB1 protein] CTD PMID:12720544 3-bromopyruvic acid increases expression ISO RGD:731644 6480464 bromopyruvate results in increased expression of RPS6KB1 protein modified form CTD PMID:24307199 3-chloropropane-1,2-diol decreases expression ISO RGD:731645 6480464 alpha-Chlorohydrin results in decreased expression of RPS6KB1 protein CTD PMID:33171136 3-chloropropane-1,2-diol multiple interactions ISO RGD:731644 6480464 3-methyladenine inhibits the reaction [[Diosgenin co-treated with alpha-Chlorohydrin] results in decreased phosphorylation of RPS6KB1 protein], [Diosgenin co-treated with alpha-Chlorohydrin] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35149085 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:731645 6480464 14-deoxy-11 more ... CTD PMID:30248417 3-methyladenine decreases phosphorylation EXP 6480464 3-methyladenine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:26804764 3-methyladenine increases phosphorylation ISO RGD:731644 6480464 3-methyladenine results in increased phosphorylation of RPS6KB1 protein CTD PMID:35149085 3-methyladenine multiple interactions ISO RGD:731644 6480464 3-methyladenine inhibits the reaction [[Diosgenin co-treated with alpha-Chlorohydrin] results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:35149085 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of RPS6KB1 mRNA CTD PMID:19162173 4'-epidoxorubicin multiple interactions ISO RGD:731644 6480464 Gossypol inhibits the reaction [Epirubicin results in increased phosphorylation of RPS6KB1 protein], MK 2206 inhibits the reaction [Epirubicin results in increased phosphorylation of RPS6KB1 protein] CTD PMID:35872041 4'-epidoxorubicin increases phosphorylation ISO RGD:731644 6480464 Epirubicin results in increased phosphorylation of RPS6KB1 protein CTD PMID:35872041 4,4'-diaminodiphenylmethane decreases expression ISO RGD:731645 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of RPS6KB1 mRNA CTD PMID:18648102 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of RPS6KB1 mRNA CTD PMID:30723492 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:731644 6480464 [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of RPS6KB1 protein CTD PMID:30259641 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases phosphorylation ISO RGD:731644 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of RPS6KB1 protein CTD PMID:30259641 4-hydroxynon-2-enal increases phosphorylation EXP 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of RPS6KB1 protein CTD PMID:19289642 4-hydroxyphenyl retinamide decreases expression ISO RGD:731645 6480464 Fenretinide results in decreased expression of RPS6KB1 mRNA CTD PMID:28973697 4-nonylphenol multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of RPS6KB1 protein] more ... CTD PMID:26804764 , PMID:28041982 4-nonylphenol decreases phosphorylation EXP 6480464 4-nonylphenol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:26804764 , PMID:28041982 4-tert-Octylphenol increases phosphorylation ISO RGD:731644 6480464 4-tert-octylphenol results in increased phosphorylation of RPS6KB1 protein CTD PMID:32466334 5-aza-2'-deoxycytidine multiple interactions ISO RGD:731644 6480464 Decitabine inhibits the reaction [sodium arsenite results in increased phosphorylation of RPS6KB1 protein] CTD PMID:26432159 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO RGD:731645 6480464 6-chloro-2 more ... CTD PMID:30209975 9-cis-retinoic acid multiple interactions ISO RGD:731645 6480464 [15-deoxy-delta(12 more ... CTD PMID:16611854 acadesine multiple interactions ISO RGD:731645 6480464 acadesine promotes the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:31982503 acetaldehyde increases activity ISO RGD:731644 6480464 Acetaldehyde results in increased activity of RPS6KB1 protein CTD PMID:16962100 acetaldehyde multiple interactions ISO RGD:731644 6480464 Sirolimus inhibits the reaction [Acetaldehyde results in increased activity of RPS6KB1 protein] CTD PMID:16962100 acetylsalicylic acid multiple interactions ISO RGD:731645 6480464 Aspirin results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein CTD PMID:10993886 aconitine increases expression EXP 6480464 Aconitine results in increased expression of RPS6KB1 mRNA CTD PMID:28099878 acrolein decreases expression ISO RGD:731644 6480464 Acrolein results in decreased expression of RPS6KB1 protein modified form CTD PMID:21742783 actinomycin D multiple interactions ISO RGD:731644 6480464 PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:14640974 actinomycin D multiple interactions ISO RGD:731645 6480464 PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:14640974 AICA ribonucleotide multiple interactions EXP 6480464 AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein], naringin inhibits the reaction [AICA ribonucleotide results in increased phosphorylation of RPS6KB1 protein] CTD PMID:15342961 , PMID:21195169 AICA ribonucleotide decreases phosphorylation EXP 6480464 AICA ribonucleotide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:28041982 AICA ribonucleotide increases phosphorylation EXP 6480464 AICA ribonucleotide results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 aldehydo-D-glucosamine decreases phosphorylation ISO RGD:731644 6480464 Glucosamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19254699 aldehydo-D-glucose increases phosphorylation ISO RGD:731645 6480464 Glucose results in increased phosphorylation of RPS6KB1 protein CTD PMID:30459625 aldehydo-D-glucose multiple interactions ISO RGD:731645 6480464 HU 308 inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein], Sirolimus inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30459625 , PMID:35445903 all-trans-retinoic acid decreases expression ISO RGD:731644 6480464 Tretinoin results in decreased expression of RPS6KB1 mRNA, Tretinoin results in decreased expression of RPS6KB1 protein modified form CTD PMID:15498508 more ... alpha,alpha-trehalose multiple interactions ISO RGD:731645 6480464 Trehalose inhibits the reaction [Cholesterol inhibits the reaction [Cadmium Chloride results in increased cleavage of RPS6KB1 protein]] more ... CTD PMID:29486218 , PMID:32773031 alpha,alpha-trehalose decreases phosphorylation ISO RGD:731645 6480464 Trehalose results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29486218 alpha-(methylamino)isobutyric acid multiple interactions ISO RGD:731644 6480464 2-(methylamino)isobutyric acid inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein] CTD PMID:22215663 alternariol decreases phosphorylation ISO RGD:731645 6480464 alternariol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25456271 amino acid multiple interactions ISO RGD:731645 6480464 [EIF2AK4 gene mutant form affects the susceptibility to Amino Acids deficiency] which results in increased phosphorylation of RPS6KB1 protein, Tunicamycin inhibits the reaction [[EIF2AK4 gene mutant form affects the susceptibility to Amino Acids deficiency] which results in increased phosphorylation of RPS6KB1 protein] CTD PMID:29449374 amiodarone decreases phosphorylation ISO RGD:731644 6480464 Amiodarone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:23912912 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of RPS6KB1 mRNA CTD PMID:16483693 ammonium chloride decreases phosphorylation ISO RGD:731645 6480464 Ammonium Chloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31310755 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:731645 6480464 pyrazolanthrone affects the reaction [flufenoxuron results in decreased phosphorylation of RPS6KB1 protein] more ... CTD PMID:20589738 more ... anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:731644 6480464 pyrazolanthrone inhibits the reaction [Ketoglutaric Acids results in increased phosphorylation of RPS6KB1 protein] CTD PMID:31051157 anthra[1,9-cd]pyrazol-6(2H)-one decreases activity ISO RGD:731644 6480464 pyrazolanthrone results in decreased activity of RPS6KB1 protein CTD PMID:12534346 ANTIMYCIN multiple interactions ISO RGD:731644 6480464 oxophenylarsine inhibits the reaction [antimycin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:16183647 ANTIMYCIN decreases phosphorylation ISO RGD:731644 6480464 antimycin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16183647 apigenin decreases expression ISO RGD:731644 6480464 Apigenin results in decreased expression of RPS6KB1 protein CTD PMID:15947208 arachidonic acid multiple interactions ISO RGD:731644 6480464 Arachidonic Acid promotes the reaction [Quercetin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:20551291 arsane multiple interactions ISO RGD:731644 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:32802178 arsenic atom multiple interactions ISO RGD:731644 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:32802178 arsenite(3-) increases phosphorylation EXP 6480464 arsenite results in increased phosphorylation of RPS6KB1 protein CTD PMID:17038550 , PMID:20377179 arsenite(3-) increases phosphorylation ISO RGD:731645 6480464 arsenite results in increased phosphorylation of RPS6KB1 protein CTD PMID:22215663 arsenite(3-) decreases phosphorylation ISO RGD:731645 6480464 arsenite results in decreased phosphorylation of RPS6KB1 protein CTD PMID:20589738 arsenite(3-) multiple interactions ISO RGD:731645 6480464 1 more ... CTD PMID:14516795 more ... arsenite(3-) increases phosphorylation ISO RGD:731644 6480464 arsenite results in increased phosphorylation of RPS6KB1 protein CTD PMID:22215663 arsenite(3-) multiple interactions ISO RGD:731644 6480464 2-(methylamino)isobutyric acid inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:22215663 , PMID:31781319 arsenite(3-) multiple interactions EXP 6480464 Quercetin inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein] CTD PMID:20377179 arsenous acid multiple interactions ISO RGD:731644 6480464 Arsenic Trioxide inhibits the reaction [lonidamine results in increased phosphorylation of RPS6KB1 protein], Arsenic Trioxide inhibits the reaction [Sorafenib results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21889928 , PMID:25416439 arsenous acid decreases expression ISO RGD:731644 6480464 Arsenic Trioxide results in decreased expression of RPS6KB1 protein modified form CTD PMID:20574048 arsenous acid increases phosphorylation ISO RGD:731644 6480464 Arsenic Trioxide results in increased phosphorylation of RPS6KB1 protein, Arsenic Trioxide results in increased phosphorylation of S6K protein CTD PMID:18048359 , PMID:25758096 arsenous acid decreases phosphorylation ISO RGD:731644 6480464 Arsenic Trioxide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21594580 , PMID:25416439 arsenous acid decreases activity ISO RGD:731644 6480464 Arsenic Trioxide results in decreased activity of RPS6KB1 protein CTD PMID:14633726 atrazine decreases expression ISO RGD:731644 6480464 Atrazine results in decreased expression of RPS6KB1 mRNA CTD PMID:22378314 aucubin increases phosphorylation ISO RGD:731644 6480464 aucubin results in increased phosphorylation of RPS6KB1 protein CTD PMID:29408431 avobenzone increases phosphorylation ISO RGD:731644 6480464 avobenzone results in increased phosphorylation of RPS6KB1 protein CTD PMID:29981360 azathioprine increases phosphorylation ISO RGD:731644 6480464 Azathioprine results in increased phosphorylation of RPS6KB1 protein CTD PMID:23958494 azathioprine multiple interactions ISO RGD:731644 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Azathioprine results in increased phosphorylation of RPS6KB1 protein] CTD PMID:23958494 azathioprine decreases phosphorylation ISO RGD:731645 6480464 Azathioprine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:23958494 bafilomycin A1 decreases phosphorylation ISO RGD:731645 6480464 bafilomycin A1 results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31310755 bafilomycin A1 multiple interactions EXP 6480464 bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein], bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:22689575 baicalein multiple interactions ISO RGD:731645 6480464 baicalein results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein CTD PMID:24560969 BAPTA multiple interactions ISO RGD:731644 6480464 oxophenylarsine inhibits the reaction [1 more ... CTD PMID:16183647 BAPTA decreases phosphorylation ISO RGD:731644 6480464 1 more ... CTD PMID:16183647 benzo[a]pyrene multiple interactions ISO RGD:731644 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:32802178 benzo[a]pyrene diol epoxide I increases expression ISO RGD:731644 6480464 7 more ... CTD PMID:26238291 benzofurans multiple interactions ISO RGD:731644 6480464 Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30696844 beta-D-glucosamine decreases phosphorylation ISO RGD:731644 6480464 Glucosamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19254699 beta-thujaplicin decreases phosphorylation ISO RGD:731645 6480464 beta-thujaplicin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25044443 bicalutamide multiple interactions ISO RGD:731644 6480464 [bicalutamide co-treated with Testosterone] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21036700 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:731644 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Diethylhexyl Phthalate results in increased expression of RPS6KB1 mRNA], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Diethylhexyl Phthalate results in increased expression of RPS6KB1 protein] CTD PMID:23793038 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:731644 6480464 Diethylhexyl Phthalate results in decreased expression of RPS6KB1 protein CTD PMID:31163220 bis(2-ethylhexyl) phthalate increases expression ISO RGD:731644 6480464 Diethylhexyl Phthalate results in increased expression of RPS6KB1 mRNA, Diethylhexyl Phthalate results in increased expression of RPS6KB1 protein CTD PMID:23793038 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of RPS6KB1 mRNA CTD PMID:25181051 more ... bisphenol A increases phosphorylation ISO RGD:731644 6480464 bisphenol A results in increased phosphorylation of RPS6KB1 protein CTD PMID:32466334 bisphenol A decreases expression ISO RGD:731645 6480464 bisphenol A results in decreased expression of RPS6KB1 mRNA CTD PMID:33221593 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of RPS6KB1 mRNA CTD PMID:27539358 bisphenol A decreases phosphorylation EXP 6480464 bisphenol A results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27296223 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of RPS6KB1 mRNA CTD PMID:27296223 BMS-754807 decreases phosphorylation ISO RGD:731644 6480464 BMS 754807 results in decreased phosphorylation of RPS6KB1 protein CTD PMID:24986516 BMS-754807 multiple interactions ISO RGD:731644 6480464 [[CDK4 mutant form co-treated with CDK6 mutant form] results in increased susceptibility to BMS 754807] which results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:24986516 bortezomib increases expression ISO RGD:731644 6480464 Bortezomib results in increased expression of RPS6KB1 mRNA CTD PMID:20977926 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of RPS6KB1 mRNA CTD PMID:15056800 bucladesine multiple interactions ISO RGD:731644 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RPS6KB1 mRNA CTD PMID:20823114 butan-1-ol multiple interactions ISO RGD:731644 6480464 1-Butanol inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of RPS6KB1 protein], 1-Butanol inhibits the reaction [PDGFB protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:15255942 , PMID:15919668 butan-1-ol multiple interactions EXP 6480464 1-Butanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of RPS6KB1 protein], 1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein] CTD PMID:14769825 , PMID:15705590 butanal decreases expression ISO RGD:731644 6480464 butyraldehyde results in decreased expression of RPS6KB1 mRNA CTD PMID:26079696 Butylparaben decreases phosphorylation ISO RGD:731644 6480464 butylparaben results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29319206 Butylparaben multiple interactions ISO RGD:731644 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [butylparaben results in decreased phosphorylation of RPS6KB1 protein], U 0126 inhibits the reaction [butylparaben results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:29319206 C.I. Natural Red 20 multiple interactions ISO RGD:731644 6480464 shikonin promotes the reaction [Oxygen deficiency results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:28684144 cadmium atom increases phosphorylation ISO RGD:731644 6480464 Cadmium results in increased phosphorylation of RPS6KB1 protein CTD PMID:14499349 cadmium atom decreases phosphorylation EXP 6480464 Cadmium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:32693121 cadmium atom decreases phosphorylation ISO RGD:731645 6480464 Cadmium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21767558 cadmium atom multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Cadmium results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21933187 cadmium dichloride multiple interactions ISO RGD:731644 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:21195169 more ... cadmium dichloride decreases expression ISO RGD:731645 6480464 Cadmium Chloride results in decreased expression of RPS6KB1 mRNA CTD PMID:35843418 cadmium dichloride decreases phosphorylation ISO RGD:731645 6480464 Cadmium Chloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35843418 cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:18021293 more ... cadmium dichloride increases phosphorylation ISO RGD:731645 6480464 Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:21544200 , PMID:24299490 cadmium dichloride increases phosphorylation ISO RGD:731644 6480464 Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:18021293 more ... cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of RPS6KB1 mRNA CTD PMID:33453195 cadmium dichloride multiple interactions ISO RGD:731645 6480464 1 more ... CTD PMID:21544200 more ... cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of RPS6KB1 mRNA CTD PMID:21297351 cadmium dichloride multiple interactions EXP 6480464 1 more ... CTD PMID:18021293 more ... caffeine decreases expression ISO RGD:731644 6480464 Caffeine results in decreased expression of RPS6KB1 protein modified form CTD PMID:21081844 caffeine decreases phosphorylation ISO RGD:731644 6480464 Caffeine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35688186 caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of RPS6KB1 protein modified form CTD PMID:21081844 calciol decreases phosphorylation ISO RGD:731644 6480464 Cholecalciferol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:18628207 calcium atom multiple interactions EXP 6480464 Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein] CTD PMID:12935885 calcium atom multiple interactions ISO RGD:731644 6480464 [Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form, dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form] CTD PMID:23680031 calcium(0) multiple interactions EXP 6480464 Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein] CTD PMID:12935885 calcium(0) multiple interactions ISO RGD:731644 6480464 [Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form, dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form] CTD PMID:23680031 calyculin a increases phosphorylation EXP 6480464 calyculin A results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 cannabidiol multiple interactions ISO RGD:731644 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of RPS6KB1 mRNA CTD PMID:30096889 cantharidin increases phosphorylation EXP 6480464 Cantharidin results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 capsaicin decreases phosphorylation ISO RGD:731644 6480464 Capsaicin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22226932 capsaicin increases phosphorylation ISO RGD:731644 6480464 Capsaicin results in increased phosphorylation of RPS6KB1 mRNA CTD PMID:36044967 carbachol multiple interactions ISO RGD:731644 6480464 1-Butanol inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of RPS6KB1 protein], Carbachol results in increased phosphorylation of and results in increased activity of RPS6KB1 protein CTD PMID:15255942 carbon disulfide affects phosphorylation EXP 6480464 Carbon Disulfide affects the phosphorylation of RPS6KB1 protein CTD PMID:27530093 celastrol multiple interactions EXP 6480464 celastrol inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein], PTEN protein promotes the reaction [celastrol inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein]] CTD PMID:24111524 chloroquine decreases phosphorylation ISO RGD:731645 6480464 Chloroquine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31310755 chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:22689575 chloroquine increases expression ISO RGD:731645 6480464 Chloroquine results in increased expression of RPS6KB1 protein modified form CTD PMID:25884947 cholesterol multiple interactions ISO RGD:731645 6480464 Trehalose inhibits the reaction [Cholesterol inhibits the reaction [Cadmium Chloride results in increased cleavage of RPS6KB1 protein]], Trehalose inhibits the reaction [Cholesterol results in increased phosphorylation of RPS6KB1 protein] CTD PMID:29486218 cholesterol increases phosphorylation ISO RGD:731645 6480464 Cholesterol results in increased phosphorylation of RPS6KB1 protein CTD PMID:29486218 chromium atom multiple interactions ISO RGD:731645 6480464 Acetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:18569013 chromium atom decreases phosphorylation ISO RGD:731645 6480464 Chromium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:18569013 chromium(6+) increases phosphorylation EXP 6480464 chromium hexavalent ion results in increased phosphorylation of RPS6KB1 protein CTD PMID:30236763 chromium(6+) multiple interactions EXP 6480464 Sirolimus inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30236763 chromium(6+) increases phosphorylation ISO RGD:731644 6480464 chromium hexavalent ion results in increased phosphorylation of RPS6KB1 protein CTD PMID:30236763 chromium(6+) multiple interactions ISO RGD:731644 6480464 Sirolimus inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30236763 chrysophanol decreases phosphorylation ISO RGD:731644 6480464 chrysophanic acid results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30300626 cisplatin increases expression ISO RGD:731645 6480464 Cisplatin results in increased expression of RPS6KB1 mRNA CTD PMID:21151649 cisplatin decreases phosphorylation EXP 6480464 Cisplatin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29476062 cisplatin multiple interactions EXP 6480464 trichostatin A promotes the reaction [Cisplatin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:29476062 cisplatin decreases phosphorylation ISO RGD:731645 6480464 Cisplatin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29476062 cisplatin multiple interactions ISO RGD:731645 6480464 trichostatin A promotes the reaction [Cisplatin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:29476062 clofibrate affects phosphorylation EXP 6480464 Clofibrate affects the phosphorylation of RPS6KB1 protein CTD PMID:16616211 cobalt dichloride increases phosphorylation ISO RGD:731644 6480464 cobaltous chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:25446852 cobalt dichloride multiple interactions EXP 6480464 [cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:24989011 cobalt dichloride multiple interactions ISO RGD:731644 6480464 Flavanones inhibits the reaction [cobaltous chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:25446852 copper atom multiple interactions ISO RGD:731644 6480464 [Chelating Agents binds to Copper] which results in increased expression of RPS6KB1 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO RGD:731644 6480464 [Chelating Agents binds to Copper] which results in increased expression of RPS6KB1 mRNA CTD PMID:30911355 copper(II) chloride increases phosphorylation ISO RGD:731645 6480464 cupric chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:32512069 copper(II) sulfate increases expression ISO RGD:731644 6480464 Copper Sulfate results in increased expression of RPS6KB1 mRNA CTD PMID:19549813 Corynoxine B multiple interactions ISO RGD:731644 6480464 corynoxine B promotes the reaction [manganese chloride results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:30578841 Corynoxine B decreases phosphorylation ISO RGD:731644 6480464 corynoxine B results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30578841 coumarin decreases phosphorylation ISO RGD:731644 6480464 coumarin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35688186 crocidolite asbestos decreases expression ISO RGD:731644 6480464 Asbestos, Crocidolite results in decreased expression of RPS6KB1 protein modified form CTD PMID:21570478 cucurbitacin E multiple interactions ISO RGD:731645 6480464 cucurbitacin E inhibits the reaction [Thioacetamide results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27363783 cucurbitacin E decreases phosphorylation EXP 6480464 cucurbitacin E results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27363783 curcumin decreases phosphorylation ISO RGD:731644 6480464 Curcumin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:18790744 , PMID:34634291 curcumin multiple interactions ISO RGD:731645 6480464 Curcumin inhibits the reaction [Thioacetamide results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27363783 curcumin multiple interactions ISO RGD:731644 6480464 Curcumin analog inhibits the reaction [Oxygen deficiency results in increased phosphorylation of RPS6KB1 protein] CTD PMID:20554536 cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]] CTD PMID:22689575 D-glucose multiple interactions ISO RGD:731645 6480464 HU 308 inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein], Sirolimus inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30459625 , PMID:35445903 D-glucose increases phosphorylation ISO RGD:731645 6480464 Glucose results in increased phosphorylation of RPS6KB1 protein CTD PMID:30459625 dactolisib decreases phosphorylation ISO RGD:731644 6480464 dactolisib results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21464613 daunorubicin increases phosphorylation ISO RGD:731644 6480464 Daunorubicin results in increased phosphorylation of RPS6KB1 protein CTD PMID:21898527 daunorubicin decreases expression EXP 6480464 Daunorubicin results in decreased expression of RPS6KB1 mRNA CTD PMID:28099878 daunorubicin multiple interactions ISO RGD:731644 6480464 Sirolimus inhibits the reaction [Daunorubicin results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21898527 deguelin decreases expression ISO RGD:731644 6480464 deguelin metabolite results in decreased expression of RPS6KB1 protein, deguelin results in decreased expression of RPS6KB1 protein CTD PMID:19139008 deguelin decreases phosphorylation ISO RGD:731644 6480464 deguelin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27255535 deoxynivalenol multiple interactions ISO RGD:731645 6480464 lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:34506767 deoxynivalenol decreases phosphorylation ISO RGD:731645 6480464 deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34506767 dexamethasone multiple interactions ISO RGD:731644 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein more ... CTD PMID:15070696 more ... dexamethasone decreases phosphorylation ISO RGD:731645 6480464 Dexamethasone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22733784 , PMID:22936724 dexamethasone multiple interactions ISO RGD:731645 6480464 14-deoxy-11 more ... CTD PMID:22733784 more ... dexamethasone decreases phosphorylation ISO RGD:731644 6480464 Dexamethasone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:15070696 dextran sulfate increases phosphorylation ISO RGD:731645 6480464 Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein CTD PMID:31676321 dextran sulfate multiple interactions ISO RGD:731644 6480464 dorsomorphin inhibits the reaction [Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein]], Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:31926917 dextran sulfate decreases phosphorylation ISO RGD:731645 6480464 Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27611972 , PMID:31926917 dextran sulfate decreases phosphorylation ISO RGD:731644 6480464 Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31926917 dextran sulfate multiple interactions ISO RGD:731645 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein]] more ... CTD PMID:27611972 more ... diarsenic trioxide decreases phosphorylation ISO RGD:731644 6480464 Arsenic Trioxide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21594580 , PMID:25416439 diarsenic trioxide decreases activity ISO RGD:731644 6480464 Arsenic Trioxide results in decreased activity of RPS6KB1 protein CTD PMID:14633726 diarsenic trioxide increases phosphorylation ISO RGD:731644 6480464 Arsenic Trioxide results in increased phosphorylation of RPS6KB1 protein, Arsenic Trioxide results in increased phosphorylation of S6K protein CTD PMID:18048359 , PMID:25758096 diarsenic trioxide multiple interactions ISO RGD:731644 6480464 Arsenic Trioxide inhibits the reaction [lonidamine results in increased phosphorylation of RPS6KB1 protein], Arsenic Trioxide inhibits the reaction [Sorafenib results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21889928 , PMID:25416439 diarsenic trioxide decreases expression ISO RGD:731644 6480464 Arsenic Trioxide results in decreased expression of RPS6KB1 protein modified form CTD PMID:20574048 dibenziodolium multiple interactions ISO RGD:731644 6480464 diphenyleneiodonium inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:21984483 Dictamnine multiple interactions ISO RGD:731644 6480464 [dictamnine co-treated with Oxygen deficiency] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30266538 dieckol decreases expression ISO RGD:731644 6480464 dieckol results in decreased expression of RPS6KB1 protein CTD PMID:31291034 digitoxin multiple interactions ISO RGD:731644 6480464 [Digitoxin co-treated with Oxygen deficiency] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34717917 digitoxin decreases phosphorylation ISO RGD:731644 6480464 Digitoxin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34717917 dihydrolipoic acid multiple interactions EXP 6480464 dihydrolipoic acid inhibits the reaction [PDGFB protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21251946 Dihydrotanshinone I decreases phosphorylation ISO RGD:731644 6480464 dihydrotanshinone I results in decreased phosphorylation of RPS6KB1 protein CTD PMID:26282490 dimercaprol multiple interactions ISO RGD:731644 6480464 Dimercaprol inhibits the reaction [oxophenylarsine results in increased phosphorylation of RPS6KB1 protein] CTD PMID:16183647 Dinitramine decreases phosphorylation ISO RGD:731645 6480464 dinitramine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:33288293 dioscin decreases expression ISO RGD:731644 6480464 dioscin results in decreased expression of RPS6KB1 mRNA CTD PMID:29990575 diosgenin multiple interactions ISO RGD:731644 6480464 3-methyladenine inhibits the reaction [[Diosgenin co-treated with alpha-Chlorohydrin] results in decreased phosphorylation of RPS6KB1 protein], [Diosgenin co-treated with alpha-Chlorohydrin] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35149085 dioxygen increases phosphorylation ISO RGD:731644 6480464 Oxygen deficiency results in increased phosphorylation of RPS6KB1 protein, Oxygen results in increased phosphorylation of RPS6KB1 protein CTD PMID:19587783 , PMID:20554536 dioxygen decreases phosphorylation ISO RGD:731644 6480464 Oxygen deficiency results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34717917 dioxygen multiple interactions ISO RGD:731644 6480464 [dictamnine co-treated with Oxygen deficiency] results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:20554536 more ... dodecanoic acid multiple interactions ISO RGD:731645 6480464 lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:34506767 dopamine decreases phosphorylation ISO RGD:731644 6480464 Dopamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19410601 dorsomorphin multiple interactions ISO RGD:731644 6480464 dorsomorphin inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein] more ... CTD PMID:23111315 more ... dorsomorphin multiple interactions ISO RGD:731645 6480464 dorsomorphin inhibits the reaction [14-deoxy-11 more ... CTD PMID:29859833 more ... dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [4-nonylphenol results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:28041982 doxorubicin multiple interactions ISO RGD:731645 6480464 NRG1 protein affects the reaction [Doxorubicin affects the phosphorylation of RPS6KB1 protein] CTD PMID:15833803 doxorubicin decreases expression ISO RGD:731644 6480464 Doxorubicin results in decreased expression of RPS6KB1 mRNA CTD PMID:29803840 doxorubicin affects expression EXP 6480464 Doxorubicin affects the expression of RPS6KB1 mRNA CTD PMID:28099878 doxorubicin increases phosphorylation EXP 6480464 Doxorubicin results in increased phosphorylation of RPS6KB1 protein CTD PMID:27666003 enzacamene increases phosphorylation ISO RGD:731644 6480464 enzacamene results in increased phosphorylation of RPS6KB1 protein CTD PMID:30597193 erlotinib hydrochloride multiple interactions ISO RGD:731644 6480464 resveratrol promotes the reaction [Erlotinib Hydrochloride results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:25895606 erlotinib hydrochloride decreases phosphorylation ISO RGD:731644 6480464 Erlotinib Hydrochloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21655094 , PMID:25895606 ethanol multiple interactions EXP 6480464 Ethanol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein] CTD PMID:12935885 ethanol affects splicing ISO RGD:731645 6480464 Ethanol affects the splicing of RPS6KB1 mRNA CTD PMID:30319688 ethanol decreases phosphorylation EXP 6480464 Ethanol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:17685400 ethanol decreases phosphorylation ISO RGD:731645 6480464 Ethanol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:18317950 , PMID:18377926 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions EXP 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21544200 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO RGD:731645 6480464 Egtazic Acid inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein], Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:14516795 , PMID:21544200 everolimus multiple interactions EXP 6480464 Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]] CTD PMID:24989011 everolimus multiple interactions ISO RGD:731644 6480464 Everolimus inhibits the reaction [Estradiol results in increased phosphorylation of RPS6KB1 protein], Everolimus inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:16033851 , PMID:19567381 fasudil decreases activity ISO RGD:731644 6480464 fasudil results in decreased activity of RPS6KB1 protein CTD PMID:10998351 fingolimod hydrochloride decreases phosphorylation ISO RGD:731644 6480464 Fingolimod Hydrochloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25939952 flavanones decreases phosphorylation ISO RGD:731644 6480464 Flavanones results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25446852 flavanones multiple interactions ISO RGD:731644 6480464 Flavanones inhibits the reaction [cobaltous chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:25446852 flavokawain B decreases phosphorylation ISO RGD:731644 6480464 flavokawain B results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30025493 flavokawain B multiple interactions ISO RGD:731644 6480464 TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:30025493 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of RPS6KB1 mRNA CTD PMID:18035473 flufenoxuron multiple interactions ISO RGD:731645 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [flufenoxuron results in decreased phosphorylation of RPS6KB1 protein] more ... CTD PMID:33771252 flufenoxuron decreases phosphorylation ISO RGD:731645 6480464 flufenoxuron results in decreased phosphorylation of RPS6KB1 protein CTD PMID:33771252 flutamide increases expression EXP 6480464 Flutamide results in increased expression of RPS6KB1 mRNA CTD PMID:24136188 formaldehyde decreases expression ISO RGD:731644 6480464 Formaldehyde results in decreased expression of RPS6KB1 mRNA CTD PMID:23649840 frenolicin B decreases phosphorylation ISO RGD:731644 6480464 frenolicin B results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30661989 Fusaric acid increases phosphorylation ISO RGD:731645 6480464 Fusaric Acid results in increased phosphorylation of RPS6KB1 protein CTD PMID:32156565 galangin decreases phosphorylation ISO RGD:731644 6480464 galangin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25450235 gefitinib decreases phosphorylation ISO RGD:731644 6480464 gefitinib results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21655094 genistein decreases expression ISO RGD:731645 6480464 Genistein results in decreased expression of RPS6KB1 mRNA CTD PMID:24967385 gingerol decreases expression ISO RGD:731644 6480464 gingerol results in decreased expression of RPS6KB1 protein modified form CTD PMID:28249781 ginsenoside Re increases phosphorylation ISO RGD:731645 6480464 ginsenoside Re results in increased phosphorylation of RPS6KB1 protein CTD PMID:17885204 glucose multiple interactions ISO RGD:731645 6480464 HU 308 inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein], Sirolimus inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30459625 , PMID:35445903 glucose increases phosphorylation ISO RGD:731645 6480464 Glucose results in increased phosphorylation of RPS6KB1 protein CTD PMID:30459625 glutathione increases expression EXP 6480464 Glutathione deficiency results in increased expression of RPS6KB1 mRNA CTD PMID:15345336 glycerol 2-phosphate multiple interactions ISO RGD:731644 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein more ... CTD PMID:23111315 glyphosate decreases expression ISO RGD:731644 6480464 glyphosate results in decreased expression of RPS6KB1 mRNA CTD PMID:31295307 glyphosate increases expression ISO RGD:731644 6480464 glyphosate results in increased expression of RPS6KB1 mRNA CTD PMID:31874349 gold atom multiple interactions ISO RGD:731644 6480464 [Quercetin analog co-treated with Gold analog] results in decreased expression of RPS6KB1 protein CTD PMID:27470402 gold(0) multiple interactions ISO RGD:731644 6480464 [Quercetin analog co-treated with Gold analog] results in decreased expression of RPS6KB1 protein CTD PMID:27470402 gossypol multiple interactions ISO RGD:731644 6480464 Gossypol inhibits the reaction [Epirubicin results in increased phosphorylation of RPS6KB1 protein] CTD PMID:35872041 hexadecanoic acid decreases phosphorylation ISO RGD:731644 6480464 Palmitic Acid results in decreased phosphorylation of RPS6KB1 protein CTD PMID:28073184 hexadecanoic acid multiple interactions EXP 6480464 [Palmitic Acid co-treated with sodium bisulfide] inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:35577173 HU-308 multiple interactions ISO RGD:731645 6480464 HU 308 inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30459625 hydrogen peroxide increases expression ISO RGD:731644 6480464 Hydrogen Peroxide results in increased expression of RPS6KB1 protein CTD PMID:18603805 hydrogen peroxide multiple interactions EXP 6480464 1-Butanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:15705590 , PMID:25304210 hydrogen peroxide decreases phosphorylation ISO RGD:731644 6480464 Hydrogen Peroxide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19451193 hydrogen sulfide increases phosphorylation ISO RGD:731645 6480464 Hydrogen Sulfide results in increased phosphorylation of RPS6KB1 protein CTD PMID:31843631 IC-87114 decreases phosphorylation ISO RGD:731645 6480464 IC 87114 results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16179367 indometacin increases expression EXP 6480464 Indomethacin results in increased expression of RPS6KB1 mRNA CTD PMID:18299717 irinotecan multiple interactions ISO RGD:731644 6480464 [Irinotecan co-treated with rucaparib] results in decreased expression of RPS6KB1 protein CTD PMID:30612311 isoprenaline increases phosphorylation ISO RGD:731645 6480464 Isoproterenol results in increased phosphorylation of RPS6KB1 protein CTD PMID:18812163 isoprenaline affects expression EXP 6480464 Isoproterenol affects the expression of RPS6KB1 mRNA CTD PMID:28099878 ivermectin decreases expression ISO RGD:731644 6480464 Ivermectin results in decreased expression of RPS6KB1 protein CTD PMID:32959892 KN-93 multiple interactions EXP 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21933187 L-ascorbic acid 2-phosphate multiple interactions ISO RGD:731644 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein more ... CTD PMID:23111315 lead diacetate decreases phosphorylation EXP 6480464 lead acetate results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22811615 , PMID:32879255 lead nitrate increases phosphorylation EXP 6480464 lead nitrate results in increased phosphorylation of RPS6KB1 protein CTD PMID:27762461 lead nitrate multiple interactions EXP 6480464 puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27762461 Licochalcone A decreases expression ISO RGD:731644 6480464 licochalcone A results in decreased expression of RPS6KB1 mRNA CTD PMID:30055311 Licochalcone B decreases phosphorylation ISO RGD:731644 6480464 licochalcone B results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35948134 lonidamine multiple interactions ISO RGD:731644 6480464 arsenic trioxide inhibits the reaction [lonidamine results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21889928 lonidamine increases phosphorylation ISO RGD:731644 6480464 lonidamine results in increased phosphorylation of RPS6KB1 protein CTD PMID:21889928 LY294002 multiple interactions ISO RGD:731644 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:15297429 more ... LY294002 decreases phosphorylation ISO RGD:731645 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16179367 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [EDN1 protein results in increased activity of RPS6KB1 protein] more ... CTD PMID:12411397 , PMID:14769825 LY294002 decreases phosphorylation ISO RGD:731644 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21976531 , PMID:27542212 LY294002 multiple interactions ISO RGD:731645 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:14516795 more ... LY294002 decreases expression ISO RGD:731644 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of RPS6KB1 protein modified form CTD PMID:23255002 manganese(II) chloride increases phosphorylation EXP 6480464 manganese chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342272 manganese(II) chloride decreases phosphorylation ISO RGD:731644 6480464 manganese chloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30578841 manganese(II) chloride multiple interactions ISO RGD:731644 6480464 corynoxine B promotes the reaction [manganese chloride results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:30578841 manganese(II) chloride decreases phosphorylation EXP 6480464 manganese chloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:23604964 medroxyprogesterone acetate multiple interactions ISO RGD:731644 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RPS6KB1 mRNA CTD PMID:20823114 metformin multiple interactions ISO RGD:731645 6480464 3-benzyl-5-((2-nitrophenoxy)methyl)dihydrofuran-2(3H)-one inhibits the reaction [Metformin inhibits the reaction [lipopolysaccharide more ... CTD PMID:29859833 metformin decreases expression ISO RGD:731644 6480464 Metformin results in decreased expression of RPS6KB1 protein modified form CTD PMID:33838154 metformin multiple interactions ISO RGD:731644 6480464 [Paclitaxel co-treated with Metformin] results in decreased expression of RPS6KB1 mRNA, Metformin inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein] CTD PMID:29309887 , PMID:34432352 methamphetamine decreases phosphorylation EXP 6480464 Methamphetamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34374793 methidathion decreases expression ISO RGD:731645 6480464 methidathion results in decreased expression of RPS6KB1 mRNA CTD PMID:34813904 methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of RPS6KB1 mRNA CTD PMID:15120968 methoxyacetic acid affects expression EXP 6480464 methoxyacetic acid affects the expression of RPS6KB1 mRNA CTD PMID:20864626 metoprolol increases expression EXP 6480464 Metoprolol results in increased expression of RPS6KB1 mRNA CTD PMID:28099878 miconazole decreases expression ISO RGD:731645 6480464 Miconazole results in decreased expression of RPS6KB1 mRNA CTD PMID:27462272 microcystin-LR multiple interactions ISO RGD:731644 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:26506538 more ... microcystin-LR increases phosphorylation ISO RGD:731645 6480464 cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein CTD PMID:31714646 microcystin-LR increases expression ISO RGD:731644 6480464 cyanoginosin LR results in increased expression of RPS6KB1 protein modified form CTD PMID:28984034 microcystin-LR multiple interactions EXP 6480464 naringin inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein] CTD PMID:15342961 microcystin-LR increases phosphorylation EXP 6480464 cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 microcystin-LR increases phosphorylation ISO RGD:731644 6480464 cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein CTD PMID:26506538 , PMID:34432352 MK-2206 multiple interactions ISO RGD:731644 6480464 MK 2206 inhibits the reaction [Epirubicin results in increased phosphorylation of RPS6KB1 protein] CTD PMID:35872041 ML-7 multiple interactions EXP 6480464 ML 7 inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:16799973 morin increases expression ISO RGD:731644 6480464 morin results in increased expression of RPS6KB1 mRNA CTD PMID:28689916 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide decreases activity ISO RGD:731644 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of RPS6KB1 protein CTD PMID:10998351 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of RPS6KB1 protein], Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21195169 , PMID:26804764 N-acetyl-L-cysteine multiple interactions ISO RGD:731645 6480464 Acetylcysteine inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:14516795 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases phosphorylation ISO RGD:731644 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31645432 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein], Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]] CTD PMID:22689575 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:731644 6480464 Sirolimus promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:31645432 N-methyl-4-phenylpyridinium decreases phosphorylation ISO RGD:731644 6480464 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25017139 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:731645 6480464 [ULK1 protein results in decreased phosphorylation of RPS6KB1 protein] which results in increased susceptibility to 1-Methyl-4-phenylpyridinium, ULK1 protein promotes the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:25680463 N-methyl-4-phenylpyridinium decreases phosphorylation ISO RGD:731645 6480464 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25680463 N-methyl-4-phenylpyridinium decreases response to substance ISO RGD:731645 6480464 RPS6KB1 protein modified form results in decreased susceptibility to 1-Methyl-4-phenylpyridinium CTD PMID:25680463 N-methyl-N-nitrosourea multiple interactions EXP 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of RPS6KB1 protein CTD PMID:22465879 N-nitrosodimethylamine multiple interactions EXP 6480464 Dimethylnitrosamine results in increased phosphorylation of and results in increased activity of RPS6KB1 protein CTD PMID:12971962 naringin multiple interactions EXP 6480464 naringin inhibits the reaction [AICA ribonucleotide results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:15342961 , PMID:19810018 neomycin affects phosphorylation ISO RGD:731645 6480464 Neomycin affects the phosphorylation of RPS6KB1 protein CTD PMID:16537399 niclosamide decreases phosphorylation ISO RGD:731644 6480464 Niclosamide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27542212 , PMID:30258081 nicotine increases phosphorylation ISO RGD:731644 6480464 Nicotine results in increased phosphorylation of RPS6KB1 protein CTD PMID:30259641 nicotine multiple interactions ISO RGD:731645 6480464 Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:31926917 nicotine multiple interactions ISO RGD:731644 6480464 [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:30259641 , PMID:31926917 nicotinic acid multiple interactions EXP 6480464 Niacin results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein CTD PMID:12837665 nitric oxide multiple interactions ISO RGD:731644 6480464 [resveratrol results in decreased activity of RPS6KB1 protein] which results in increased abundance of Nitric Oxide, [Sirolimus results in decreased activity of RPS6KB1 protein] which results in increased abundance of Nitric Oxide CTD PMID:21544240 Nodularin increases phosphorylation EXP 6480464 nodularin results in increased phosphorylation of RPS6KB1 protein, nodularin results in increased phosphorylation of RPS6KB1 protein alternative form CTD PMID:25192816 Nonylphenol decreases expression EXP 6480464 nonylphenol results in decreased expression of RPS6KB1 mRNA CTD PMID:27832966 Nonylphenol increases expression EXP 6480464 nonylphenol results in increased expression of RPS6KB1 mRNA CTD PMID:27832966 ochratoxin A increases phosphorylation ISO RGD:731644 6480464 ochratoxin A results in increased phosphorylation of RPS6KB1 protein CTD PMID:31154016 okadaic acid multiple interactions EXP 6480464 naringin inhibits the reaction [Okadaic Acid results in increased phosphorylation of RPS6KB1 protein] CTD PMID:15342961 okadaic acid increases phosphorylation EXP 6480464 Okadaic Acid results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 oligopeptide decreases phosphorylation ISO RGD:731644 6480464 Oligopeptides analog results in decreased phosphorylation of RPS6KB1 protein CTD PMID:24875536 omipalisib decreases phosphorylation ISO RGD:731644 6480464 omipalisib results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21464613 , PMID:22733540 orotic acid increases phosphorylation ISO RGD:731644 6480464 Orotic Acid results in increased phosphorylation of RPS6KB1 protein CTD PMID:22863860 orotic acid multiple interactions ISO RGD:731644 6480464 Orotic Acid inhibits the reaction [STK11 protein results in decreased phosphorylation of RPS6KB1 protein], Sirolimus inhibits the reaction [Orotic Acid results in increased phosphorylation of RPS6KB1 protein] CTD PMID:22863860 ouabain affects expression EXP 6480464 Ouabain affects the expression of RPS6KB1 mRNA CTD PMID:28099878 p-tert-Amylphenol increases phosphorylation ISO RGD:731644 6480464 4-tert-octylphenol results in increased phosphorylation of RPS6KB1 protein CTD PMID:32466334 paclitaxel multiple interactions ISO RGD:731644 6480464 [Paclitaxel co-treated with Metformin] results in decreased expression of RPS6KB1 mRNA CTD PMID:29309887 palbociclib multiple interactions ISO RGD:731644 6480464 palbociclib promotes the reaction [BMS 754807 results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:24986516 paraquat decreases phosphorylation ISO RGD:731644 6480464 Paraquat results in decreased phosphorylation of RPS6KB1 protein CTD PMID:20929985 Parthenin multiple interactions ISO RGD:731644 6480464 benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [parthenin analog results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:25196075 Parthenin decreases phosphorylation ISO RGD:731644 6480464 parthenin analog results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25196075 PD173074 multiple interactions ISO RGD:731644 6480464 [PKI 166 co-treated with PD 173074] results in decreased activity of RPS6KB1 protein CTD PMID:15377668 phenethyl isothiocyanate decreases phosphorylation ISO RGD:731645 6480464 phenethyl isothiocyanate results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27579538 phenethyl isothiocyanate decreases phosphorylation ISO RGD:731644 6480464 phenethyl isothiocyanate results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27579538 phenobarbital affects expression ISO RGD:731644 6480464 Phenobarbital affects the expression of RPS6KB1 mRNA CTD PMID:19159669 phenylarsine oxide multiple interactions ISO RGD:731644 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [oxophenylarsine results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:16183647 phenylarsine oxide increases phosphorylation ISO RGD:731644 6480464 oxophenylarsine results in increased phosphorylation of RPS6KB1 protein CTD PMID:16183647 phenylephrine multiple interactions EXP 6480464 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3 more ... CTD PMID:12411397 more ... phenylephrine increases phosphorylation EXP 6480464 Phenylephrine results in increased phosphorylation of RPS6KB1 protein CTD PMID:15757502 , PMID:15795328 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:731645 6480464 SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:10993886 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:731644 6480464 Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein], Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30696844 phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:731644 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein CTD PMID:30696844 phosphatidic acid multiple interactions ISO RGD:731644 6480464 Phosphatidic Acids results in increased phosphorylation of and results in increased activity of RPS6KB1 protein CTD PMID:15255942 pioglitazone multiple interactions ISO RGD:731644 6480464 pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6KB1 protein] CTD PMID:26643070 pioglitazone decreases phosphorylation ISO RGD:731644 6480464 pioglitazone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:26643070 pirinixic acid decreases expression ISO RGD:731645 6480464 pirinixic acid results in decreased expression of RPS6KB1 mRNA CTD PMID:20813756 platycodin D decreases expression ISO RGD:731644 6480464 platycodin D results in decreased expression of RPS6KB1 protein modified form CTD PMID:26078792 prazosin multiple interactions EXP 6480464 Prazosin inhibits the reaction [Phenylephrine results in increased activity of RPS6KB1 protein] CTD PMID:12720544 progesterone multiple interactions EXP 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of RPS6KB1 protein CTD PMID:22465879 propranolol increases phosphorylation ISO RGD:731645 6480464 Propranolol results in increased phosphorylation of RPS6KB1 protein CTD PMID:16537399 propranolol multiple interactions ISO RGD:731645 6480464 Sirolimus inhibits the reaction [Propranolol results in increased phosphorylation of RPS6KB1 protein] CTD PMID:16537399 puerarin increases phosphorylation ISO RGD:731644 6480464 puerarin results in increased phosphorylation of RPS6KB1 protein CTD PMID:27796870 puerarin multiple interactions EXP 6480464 puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27762461 puerarin multiple interactions ISO RGD:731644 6480464 Sirolimus inhibits the reaction [puerarin results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27796870 pyrvinium decreases phosphorylation ISO RGD:731644 6480464 pyrvinium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27542212 quercetin multiple interactions ISO RGD:731644 6480464 [Quercetin analog co-treated with Gold analog] results in decreased expression of RPS6KB1 protein more ... CTD PMID:20551291 more ... quercetin multiple interactions ISO RGD:731645 6480464 Quercetin inhibits the reaction [IGF1 protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:24353828 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein] CTD PMID:20377179 quercetin decreases phosphorylation ISO RGD:731644 6480464 Quercetin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:20551291 , PMID:23094058 quercetin decreases activity ISO RGD:731644 6480464 Quercetin results in decreased activity of RPS6KB1 protein CTD PMID:10998351 rac-lactic acid decreases expression ISO RGD:731644 6480464 Lactic Acid results in decreased expression of RPS6KB1 mRNA CTD PMID:30851411 resveratrol multiple interactions ISO RGD:731644 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 more ... CTD PMID:15297429 more ... resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of RPS6KB1 protein modified form CTD PMID:25394677 resveratrol decreases phosphorylation ISO RGD:731645 6480464 resveratrol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:24304514 , PMID:26223300 resveratrol decreases phosphorylation ISO RGD:731644 6480464 resveratrol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16979140 more ... resveratrol decreases phosphorylation EXP 6480464 resveratrol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:18562309 , PMID:24304514 resveratrol decreases activity ISO RGD:731644 6480464 resveratrol results in decreased activity of RPS6KB1 protein CTD PMID:15297429 more ... resveratrol decreases expression ISO RGD:731645 6480464 resveratrol results in decreased expression of RPS6KB1 protein modified form CTD PMID:21224254 resveratrol multiple interactions ISO RGD:731645 6480464 [[resveratrol results in increased activity of SIRT1 protein] which results in decreased activity of MTOR protein] which results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:21321189 more ... resveratrol increases phosphorylation ISO RGD:731644 6480464 resveratrol results in increased phosphorylation of RPS6KB1 protein CTD PMID:23680031 resveratrol multiple interactions EXP 6480464 [Sirolimus co-treated with Resveratrol] results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:12237323 more ... resveratrol decreases expression ISO RGD:731644 6480464 resveratrol results in decreased expression of RPS6KB1 protein, resveratrol results in decreased expression of RPS6KB1 protein modified form CTD PMID:17534123 more ... rotenone decreases phosphorylation ISO RGD:731645 6480464 Rotenone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:26031332 rotenone multiple interactions EXP 6480464 [Rotenone results in increased abundance of Hydrogen Peroxide] inhibits the reaction [MTOR protein results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:25304210 rottlerin multiple interactions EXP 6480464 rottlerin inhibits the reaction [Phenylephrine results in increased activity of RPS6KB1 protein] CTD PMID:12720544 rottlerin decreases activity EXP 6480464 rottlerin results in decreased activity of RPS6KB1 protein CTD PMID:12720544 roxarsone increases expression EXP 6480464 Roxarsone results in increased expression of RPS6KB1 mRNA CTD PMID:35985552 roxarsone multiple interactions EXP 6480464 Roxarsone results in increased expression of and results in increased phosphorylation of RPS6KB1 protein, Sirolimus inhibits the reaction [Roxarsone results in increased expression of and results in increased phosphorylation of RPS6KB1 protein] CTD PMID:35985552 rucaparib multiple interactions ISO RGD:731644 6480464 [Irinotecan co-treated with rucaparib] results in decreased expression of RPS6KB1 protein CTD PMID:30612311 Salidroside multiple interactions EXP 6480464 Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]], rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:24989011 SB 203580 multiple interactions ISO RGD:731645 6480464 SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein], Sodium Salicylate inhibits the reaction [SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]] CTD PMID:10993886 SB 415286 multiple interactions ISO RGD:731644 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2, 5-dione inhibits the reaction [resveratrol results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:23292070 serpentine asbestos decreases phosphorylation ISO RGD:731644 6480464 Asbestos, Serpentine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:24735948 sertraline multiple interactions EXP 6480464 Sertraline results in increased phosphorylation of and results in increased activity of RPS6KB1 protein, Sirolimus inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:17728140 Shikonin multiple interactions ISO RGD:731644 6480464 shikonin promotes the reaction [Oxygen deficiency results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:28684144 silicon dioxide decreases phosphorylation EXP 6480464 Silicon Dioxide analog results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27613482 simvastatin multiple interactions ISO RGD:731645 6480464 FST protein inhibits the reaction [Simvastatin results in decreased phosphorylation of RPS6KB1 protein], IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:27734117 , PMID:33034787 simvastatin decreases phosphorylation ISO RGD:731645 6480464 Simvastatin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27734117 , PMID:33034787 sirolimus multiple interactions ISO RGD:731644 6480464 [Dexamethasone co-treated with Sirolimus] inhibits the reaction [IGF1 protein results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:15070696 more ... sirolimus increases expression ISO RGD:731645 6480464 Sirolimus results in increased expression of RPS6KB1 protein modified form CTD PMID:25884947 sirolimus decreases phosphorylation ISO RGD:731645 6480464 Sirolimus results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16537399 more ... sirolimus increases phosphorylation ISO RGD:731644 6480464 Sirolimus results in increased phosphorylation of RPS6KB1 protein CTD PMID:24304514 sirolimus decreases expression ISO RGD:731644 6480464 Sirolimus results in decreased expression of RPS6KB1 protein modified form CTD PMID:23255002 more ... sirolimus decreases phosphorylation EXP 6480464 Sirolimus results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16391472 , PMID:24304514 sirolimus decreases phosphorylation ISO RGD:731644 6480464 Sirolimus results in decreased phosphorylation of RPS6KB1 protein, Sirolimus results in decreased phosphorylation of S6K protein CTD PMID:15070696 more ... sirolimus decreases activity ISO RGD:731645 6480464 Sirolimus results in decreased activity of RPS6KB1 protein CTD PMID:19246562 sirolimus multiple interactions ISO RGD:731645 6480464 [Sirolimus co-treated with Resveratrol] inhibits the reaction [TSC2 gene mutant form results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:14516795 more ... sirolimus multiple interactions EXP 6480464 [Sirolimus co-treated with Resveratrol] results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:12411397 more ... sirolimus decreases activity ISO RGD:731644 6480464 [Sirolimus results in decreased activity of MTOR protein] which results in decreased activity of RPS6KB1 protein, Sirolimus results in decreased activity of RPS6KB1 protein CTD PMID:14673156 more ... sodium arsenite multiple interactions ISO RGD:731644 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:22869613 more ... sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of RPS6KB1 protein CTD PMID:26432159 sodium arsenite increases phosphorylation ISO RGD:731644 6480464 sodium arsenite results in increased phosphorylation of RPS6KB1 protein CTD PMID:26432159 , PMID:33781819 sodium arsenite decreases phosphorylation ISO RGD:731644 6480464 sodium arsenite results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22869613 sodium fluoride decreases expression ISO RGD:731645 6480464 Sodium Fluoride results in decreased expression of RPS6KB1 mRNA CTD PMID:34536393 sodium fluoride decreases phosphorylation EXP 6480464 Sodium Fluoride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34536393 sodium fluoride multiple interactions ISO RGD:731645 6480464 4 more ... CTD PMID:34536393 sodium fluoride decreases phosphorylation ISO RGD:731645 6480464 Sodium Fluoride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34536393 Sodium salicylate multiple interactions ISO RGD:731645 6480464 Sodium Salicylate inhibits the reaction [SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]] more ... CTD PMID:10993886 sorafenib multiple interactions ISO RGD:731644 6480464 arsenic trioxide inhibits the reaction [sorafenib results in increased phosphorylation of RPS6KB1 protein] CTD PMID:25416439 sorafenib decreases phosphorylation ISO RGD:731644 6480464 Sorafenib results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21858812 sorafenib increases phosphorylation ISO RGD:731644 6480464 sorafenib results in increased phosphorylation of RPS6KB1 protein CTD PMID:25416439 stilbenoid decreases phosphorylation ISO RGD:731644 6480464 Stilbenes results in decreased phosphorylation of RPS6KB1 protein CTD PMID:23059970 succimer multiple interactions ISO RGD:731645 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of RPS6KB1 mRNA CTD PMID:21641980 sulfates affects methylation ISO RGD:731644 6480464 Sulfates affects the methylation of RPS6KB1 promoter CTD PMID:25395096 sulfates multiple interactions ISO RGD:731644 6480464 [Soot co-treated with Sulfates] affects the methylation of RPS6KB1 promoter CTD PMID:25395096 sunitinib increases expression ISO RGD:731644 6480464 Sunitinib results in increased expression of RPS6KB1 mRNA CTD PMID:31533062 superoxide multiple interactions ISO RGD:731644 6480464 [resveratrol results in decreased activity of RPS6KB1 protein] which results in decreased abundance of Superoxides, [Sirolimus results in decreased activity of RPS6KB1 protein] which results in decreased abundance of Superoxides CTD PMID:21544240 swainsonine decreases phosphorylation ISO RGD:731645 6480464 Swainsonine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:36402259 tamibarotene affects expression ISO RGD:731644 6480464 tamibarotene affects the expression of RPS6KB1 mRNA CTD PMID:15498508 tamoxifen multiple interactions ISO RGD:731644 6480464 [Tamoxifen results in decreased activity of MTOR protein] which results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19931998 tamoxifen increases activity ISO RGD:731644 6480464 [Tamoxifen results in increased activity of AKT1 protein] which results in increased activity of RPS6KB1 protein CTD PMID:20372086 tamoxifen decreases phosphorylation ISO RGD:731644 6480464 Tamoxifen results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19931998 Tautomycin increases phosphorylation EXP 6480464 tautomycin results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 Temsirolimus multiple interactions ISO RGD:731644 6480464 temsirolimus promotes the reaction [2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:16954435 Temsirolimus multiple interactions ISO RGD:731645 6480464 temsirolimus inhibits the reaction [Dronabinol results in increased phosphorylation of RPS6KB1 protein] CTD PMID:32773031 Temsirolimus decreases phosphorylation ISO RGD:731644 6480464 temsirolimus results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16033649 , PMID:16954435 teriflunomide decreases phosphorylation ISO RGD:731644 6480464 teriflunomide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19174558 testosterone multiple interactions ISO RGD:731644 6480464 [bicalutamide co-treated with Testosterone] results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:21036700 testosterone decreases phosphorylation ISO RGD:731645 6480464 Testosterone deficiency results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21045173 testosterone multiple interactions ISO RGD:731645 6480464 Testosterone inhibits the reaction [Testosterone deficiency results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:21045173 testosterone increases phosphorylation ISO RGD:731644 6480464 Testosterone results in increased phosphorylation of RPS6KB1 protein CTD PMID:21036700 testosterone increases activity ISO RGD:731644 6480464 [Testosterone results in increased activity of RAF1 protein] which results in increased activity of RPS6KB1 protein CTD PMID:20372086 theobromine multiple interactions EXP 127229954 [Theobromine co-treated with Theanine] inhibits the reaction [1 more ... RGD thioacetamide increases phosphorylation ISO RGD:731645 6480464 Thioacetamide results in increased phosphorylation of RPS6KB1 protein CTD PMID:27363783 thioacetamide multiple interactions ISO RGD:731645 6480464 cucurbitacin E inhibits the reaction [Thioacetamide results in increased phosphorylation of RPS6KB1 protein], Curcumin inhibits the reaction [Thioacetamide results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27363783 Thiorphan decreases phosphorylation ISO RGD:731644 6480464 Thiorphan results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31054283 torin 1 decreases phosphorylation ISO RGD:731644 6480464 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1, 6)naphthyridin-2(1H)-one results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21858812 , PMID:25940091 torin 1 decreases phosphorylation ISO RGD:731645 6480464 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1, 6)naphthyridin-2(1H)-one results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29945972 trametinib decreases phosphorylation ISO RGD:731644 6480464 trametinib results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22733540 Tributyltin oxide decreases phosphorylation ISO RGD:731645 6480464 bis(tri-n-butyltin)oxide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22174045 Tributyltin oxide multiple interactions ISO RGD:731645 6480464 bis(tri-n-butyltin)oxide results in decreased expression of and results in decreased phosphorylation of RPS6KB1 protein CTD PMID:24375594 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of RPS6KB1 mRNA CTD PMID:19448997 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of RPS6KB1 mRNA CTD PMID:33387578 trichostatin A decreases phosphorylation EXP 6480464 trichostatin A results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29476062 trichostatin A multiple interactions ISO RGD:731645 6480464 trichostatin A promotes the reaction [Cisplatin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:29476062 trichostatin A multiple interactions EXP 6480464 trichostatin A promotes the reaction [Cisplatin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:29476062 trifluoperazine multiple interactions EXP 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21544200 trifluoperazine multiple interactions ISO RGD:731645 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21544200 troglitazone multiple interactions ISO RGD:731644 6480464 troglitazone results in decreased activity of and results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16825603 trovafloxacin multiple interactions ISO RGD:731644 6480464 [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of RPS6KB1 protein CTD PMID:33609687 tunicamycin increases expression ISO RGD:731645 6480464 Tunicamycin results in increased expression of RPS6KB1 mRNA CTD PMID:17127020 tunicamycin multiple interactions ISO RGD:731645 6480464 Tunicamycin inhibits the reaction [[EIF2AK4 gene mutant form affects the susceptibility to Amino Acids deficiency] which results in increased phosphorylation of RPS6KB1 protein] CTD PMID:29449374 ursolic acid decreases expression ISO RGD:731644 6480464 ursolic acid results in decreased expression of RPS6KB1 protein CTD PMID:24802810 usnic acid decreases phosphorylation ISO RGD:731644 6480464 usnic acid results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25078063 valproic acid increases expression ISO RGD:731644 6480464 Valproic Acid results in increased expression of RPS6KB1 mRNA CTD PMID:29154799 vanadium atom multiple interactions ISO RGD:731645 6480464 PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein], Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein CTD PMID:14971662 vanadium(0) multiple interactions ISO RGD:731645 6480464 PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein], Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein CTD PMID:14971662 wortmannin multiple interactions EXP 6480464 wortmannin inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21195169 wortmannin multiple interactions ISO RGD:731644 6480464 Wortmannin inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of RPS6KB1 protein], Wortmannin inhibits the reaction [INS protein results in increased expression of RPS6KB1 protein modified form] CTD PMID:20936651 , PMID:32802178 wortmannin multiple interactions ISO RGD:731645 6480464 wortmannin inhibits the reaction [arsenite affects the activity of RPS6KB1 protein] CTD PMID:14516795 wortmannin decreases phosphorylation ISO RGD:731644 6480464 wortmannin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25663935 zearalenone multiple interactions ISO RGD:731645 6480464 2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein] more ... CTD PMID:30394307 , PMID:31982503 zearalenone decreases phosphorylation ISO RGD:731645 6480464 Zearalenone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30394307 , PMID:31982503 zotarolimus multiple interactions ISO RGD:731644 6480464 zotarolimus inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:19567381
