Bw125 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bw125 (Body weight QTL 125) Rattus norvegicus

Symbol: Bw125
Name: Body weight QTL 125
RGD ID: 7387312
Trait: retroperitoneal fat pad mass   (VT:0010430)    
Measurement Type: retroperitoneal fat pad weight   (CMO:0000356)    
LOD Score: 3.0
P Value: 0.0047
Variance: Not Available
Inheritance Type: additive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21064,890,616 - 107,211,142RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01067,880,046 - 112,626,471RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01067,668,577 - 112,200,500RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41069,039,078 - 110,718,848RGD_MAPPER_PIPELINERGSC3.4
Cross Type: backcross
Strains Crossed: ZUC-LeprfaSte-/- BN/Crl 




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw125Ratobesity  IAGP 7365117 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw125Ratincreased retroperitoneal fat pad weight  IAGP 7365117 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw125Ratretroperitoneal fat pad weight  IEP 7365117 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw125Ratcontrol condition  IEP 7365117 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw125Ratpost excision weight measurement  IEP 7365117 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw125RatBN/Crl  IEA 7365117 RGD 
Bw125RatZUC-LeprfaSte-/-  IEA 7365117 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw125Ratretroperitoneal fat pad mass  IEP 7365117 RGD 


#
Reference Title
Reference Citation
1. Genes unlinked to the leptin receptor influence urinary albumin excretion in obese Zucker rats. Kim K, etal., Physiol Genomics. 2010 Feb 16.


1 to 20 of 1103 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1311017Utp6UTP6 small subunit processome component106489732164927997Rat
41337556LOC12009527060S ribosomal protein L12-like106494388064944475Rat
9259038Rpl12-ps8ribosomal protein L12, pseudogene 8106495466764955263Rat
1593621Suz12SUZ12 polycomb repressive complex 2 subunit106496703565012916Rat
621517Crlf3cytokine receptor-like factor 3106502422865060746Rat
7655392Rpl12-ps6ribosomal protein L12, pseudogene 6106503209765033557Rat
1561464Atad5ATPase family, AAA domain containing 5106507068265118489Rat
1306595Tefmtranscription elongation factor, mitochondrial106511965765124233Rat
7558326Pgam1-ps3phosphoglycerate mutase 1, pseudogene 3106512448665130349Rat
41337742LOC120095424small nucleolar RNA SNORA43106513290865133055Rat
1586597Nme1-ps3NME/NM23 nucleoside diphosphate kinase 1, pseudogene 3106513688465137365Rat
708487Adap2ArfGAP with dual PH domains 2106513800665166147Rat
41310478Trnaa-cgctransfer RNA alanine (anticodon CGC)106516743865167510Rat
1305252Rnf135ring finger protein 135106517056065189791Rat
1307023Rhot1ras homolog family member T1106519870065262807Rat
1311901Rhbdl3rhomboid like 3106529925065354099Rat
1310429C10h17orf75similar to human chromosome 17 open reading frame 75106536092465373864Rat
2325479Mir632microRNA 632106538575765385834Rat
1308121Zfp207zinc finger protein 207106538580765398086Rat
1306450Psmd11proteasome 26S subunit, non-ATPase 11106543385365479774Rat

1 to 20 of 1103 rows
1 to 20 of 1669 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
5050230RH133936206106497292364973128Ratregion
5053937RH142937137106497548764975624Ratregion
5500555RH135952645106500820865008853Ratregion
5063032BF398270195106501048565010680Ratregion
5500085UniSTS:236667204106501244665012650Ratregion
5034087RH141316204106502378565023989Ratregion
5053239RH142534253106507576365076016Ratregion
5063392BE107606195106511368065113875Ratregion
5079370RH140957187106511990165120088Ratregion
5074412RH138002171106512667165126842Ratregion
1639492D10Got406213106513903865139251Ratregion
5049136RH133306192106516685665167048Ratregion
5085754BM383586150106517888465179034Ratregion
5046588RH131840201106526246065262661Ratregion
5075460RH138606228106530139365301621Ratregion
5059886AI072008201106535377365353974Ratregion
5051507AI847581107106535386565353972Ratregion
5030771AW535144214106538508965385303Ratregion
5501932MARC_17513-17514:1016473117:11431106539381765395248Ratregion
5083007BF390612185106539598565396170Ratregion
1 to 20 of 1669 rows

Peak: (rs8163932)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21087,390,616 - 87,390,616RGD
Rnor_6.01090,380,046 - 90,380,046RGD
Celera1086,099,526 - 86,099,526RGD


1 to 10 of 164 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631565Hcuc4Hepatic copper content QTL 44.15liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106694181373452992Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
631555Bp134Blood pressure QTL 1340.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)108051528791230079Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
631558Bp137Blood pressure QTL 1370.013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)109472486096836268Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
12902615Bw185Body weight QTL 1850.01body mass (VT:0001259)body weight (CMO:0000012)107111521772606468Rat

1 to 10 of 164 rows


Note Type Note Reference
qtl_cross_type backcross 7365117
qtl_general number of animals used: 104 males; all were homozygous for the Lepr mutation and were obese 7365117
qtl_general measurement method: retroperitoneal fat depots of 15 wk old obese female rats was removed and weighed 7365117
qtl_general software used: R package; R/qtl and R/bqtl; Statistical analysis by ANOVA 7365117